- 著者
- 
             
             藤浪 得二
             
             相模 成一郎
             
             外山 孟生
             
             阪口 啓一
             
             山本 三郎
             
             山崎 果
             
             畑中 茂
             
             山本 義彦
             
             秋本 祐三
             
          
- 出版者
- Meeting of Osaka Dermatological Association
- 雑誌
- 皮膚 (ISSN:00181390)
- 巻号頁・発行日
- vol.4, no.3-4, pp.193-204, 1962 (Released:2010-08-25)
        The skin irritating effect of various compounds was examined and the following results were obtained.1) Alcohols and esters are, in general, non-irritating effect. Acids, lactones and phenolshave a slight irritating effect. Aldehydes are strongly irritating and halogen compounds have also a strong irritating action.2) The greater the degree of unsaturation, the stronger is the irritating effect. Double bond compounds, especially, have a strong irritating action.3) Ketones are slightly irritating but those which are readily enolized have a strong irritating action.4) The irritability of aromatic aldehydes differs according to the type and position of the substituting radical.5) Water soluble but fat insoluble and water insoluble compounds are non-irritating. Skin irritants have the property of being both water and fat soluble in a certain ratio.