著者

大隈 一裕 松田 功 勝田 康夫 岸本 由香 辻 啓介

出版者

日本応用糖質科学会

雑誌

Journal of Applied Glycoscience (ISSN:13447882)

巻号頁・発行日

vol.53, no.1, pp.65-69, 2006 (Released:2006-04-19)

参考文献数

27

被引用文献数

4 9

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In 1988 we recognized glycosylated components in pyrodextrin and started a study to obtain an amylase-resistant ingredient. We succeeded in establishing a series of processes for industrial-scale separation of the indigestible component with superior appearance and taste by roasting starch (pyrolysis), enzymatic hydrolysis, purification, chromatographic fractionation and spray drying. The component was named indigestible dextrin (ID). In order to utilize ID as a source of dietary fiber, a low-calorie ingredient, and a physiologically active ingredient, we first confirmed that ID is a highly safe ingredient by conducting an acute toxicity study, a mutagenicity study, long-term administration studies in both rats and humans, and a study of diarrhea caused by long-term consumption. A novel determination method using the enzyme-gravimetric method in combination with high performance liquid chromatography (enzyme-HPLC method) was proposed to the Association of Official Analytical Chemists (AOAC) and approved as Final Action Method AOAC 2001. 03 in January 2005. Animal and human studies showed the energy value of 1 kcal/g dietary fiber fraction. Based on these results, ID has been approved in many countries. Moreover, it has been confirmed by both animal and clinical studies that ID has physiological functions such as intestinal regularity, moderating postprandial blood glucose level, lowering serum lipid, and reducing body fat. As for the physicochemical properties of ID, it is similar to DE10 maltodextrin in sweetness and browning property. The properties of not being fermented easily by yeast or lactobacillus impart an interesting characteristic to beer and lactic acid drinks. At present ID is commercially available for use in a wide range of food products not only in Japan but also in many countries around the world.

著者

大隈 一裕 松田 功 勝田 康夫 岸本 由香 辻 啓介

出版者

日本応用糖質科学会

雑誌

Journal of applied glycoscience (ISSN:13447882)

巻号頁・発行日

vol.53, no.1, pp.65-69, 2006-01-20

参考文献数

27

被引用文献数

9

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In 1988 we recognized glycosylated components in pyrodextrin and started a study to obtain an amylase-resistant ingredient. We succeeded in establishing a series of processes for industrial-scale separation of the indigestible component with superior appearance and taste by roasting starch (pyrolysis), enzymatic hydrolysis, purification, chromatographic fractionation and spray drying. The component was named indigestible dextrin (ID). In order to utilize ID as a source of dietary fiber, a low-calorie ingredient, and a physiologically active ingredient, we first confirmed that ID is a highly safe ingredient by conducting an acute toxicity study, a mutagenicity study, long-term administration studies in both rats and humans, and a study of diarrhea caused by long-term consumption. A novel determination method using the enzyme-gravimetric method in combination with high performance liquid chromatography (enzyme-HPLC method) was proposed to the Association of Official Analytical Chemists (AOAC) and approved as Final Action Method AOAC 2001. 03 in January 2005. Animal and human studies showed the energy value of 1 kcal/g dietary fiber fraction. Based on these results, ID has been approved in many countries. Moreover, it has been confirmed by both animal and clinical studies that ID has physiological functions such as intestinal regularity, moderating postprandial blood glucose level, lowering serum lipid, and reducing body fat. As for the physicochemical properties of ID, it is similar to DE10 maltodextrin in sweetness and browning property. The properties of not being fermented easily by yeast or lactobacillus impart an interesting characteristic to beer and lactic acid drinks. At present ID is commercially available for use in a wide range of food products not only in Japan but also in many countries around the world.

著者

若林 茂 岸本 由香 南部 征喜 松岡 瑛

出版者

Japanese Association for Dietary Fiber Research

雑誌

日本食物繊維研究会誌 (ISSN:13431994)

巻号頁・発行日

vol.3, no.1, pp.13-19, 1999-06-30 (Released:2011-02-23)

参考文献数

25

被引用文献数

1

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健常成人を対象として,各種糖質負荷後の血糖およびインスリン分泌応答に及ぼす難消化性デキストリンの影響について検討した。さらに,食事負荷試験により,食後の血糖上昇に及ぼす影響について検討した。(1)10gの難消化性デキストリン摂取ではショ糖100g負荷後の血糖およびインスリン分泌応答を抑制し,頂値のレベルを非添加の88および69%に低下させた。また,グルコース509およびマルトデキストリン50g負荷に対して,難消化性デキストリンはインスリン分泌のみを抑制し,頂値のレベルは非添加のそれぞれ52および60%に低下した。(2)うどん定食(糖質104.2g,565kcal)摂取後の血糖応答は全般に急峻であり頂値は183.9mg/dlに達した。これに対し,菓子パン(糖質137.2g,553kcal)摂取時の頂値は145.3mg/dlであり,血糖応答は緩やかであった。これらの試験食負荷において難消化性デキストリンを緑茶あるいはコーヒーに添加して摂取させたところ,いずれも有意な血糖上昇抑制効果が認められ,頂値は88および84%に低下した。 以上の結果から,難消化性デキストリンは健常成人において食後の血糖上昇に対して一定の抑制効果が期待できるものと考えられた。

著者

岸本 由香 若林 茂 徳永 勝人

出版者

Japanese Association for Dietary Fiber Research

雑誌

日本食物繊維研究会誌 (ISSN:13431994)

巻号頁・発行日

vol.4, no.2, pp.59-65, 2000-12-28 (Released:2010-06-28)

参考文献数

29

被引用文献数

1

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We conducted a clinical trial in order to evaluate the effects of continual ingestion of indigestible dextrin on both glucose and lipid metabolism, and fat accumulation and its distribution in human subjects. There were twelve male subjects with either serum total-cholesterol level more than 220 mg/dl or triacylglycerol level more than 150 mg/dl. Subjects were concurrently ingested l0g of indigestible dextrin with meal (3 times/day) for three month. Each was subjected to a glucose tolerance test and CT scan at umbilical level, and also taken blood sample to measure the clinical laboratory data before and after the test period. Compared to the starting levels, percent body fat in all the subjects and the area of visceral fat in subjects with obesity were significantly decreased. Although the average peak level of serum glucose was more than 200 mg/dl at 60 min after 75 g glucose administration, glucose tolerance was improved and the average levels of serum glucose at 30, 60, and 120 min were significantly reduced after the test period. Likewise, serum total-cholesterol and triacylglycerol levels were significantly reduced. No adverse event such as diarrhea was observed through the test period. In conclusion, continual ingestion of indigestible dextrin is useful for reducing the body fat accumulation, especially visceral fat.

著者

山田 貴子 新谷 知也 飯田 哲郎 岸本 由香 大隈 一裕

出版者

Japan Society of Nutrition and Food Science

雑誌

日本栄養・食糧学会誌 (ISSN:02873516)

巻号頁・発行日

vol.70, no.6, pp.271-278, 2017 (Released:2017-12-26)

参考文献数

39

被引用文献数

1 8

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ブドウ糖果糖液糖のアルカリ異性化である希少糖含有シロップ摂取による血糖応答に及ぼす影響をヒト試験で評価した。グリセミック・インデックス (GI) 試験を行った結果, 希少糖含有シロップのGI値は49であった。次に, 空腹時血糖値126 mg/dL未満の成人50名を対象にランダム化二重盲検プラセボ対照クロスオーバーによる低用量単回試験を行った。ショ糖6 gまたは希少糖含有シロップ8.8 g (同量のブドウ糖含有量) をコーヒーに溶解し摂取させ, 120分までの血糖値およびインスリン値を観察した。希少糖含有シロップはショ糖に比べて血糖AUC (曲線下面積) およびインスリンAUCが有意に低下し, 低下率は血糖1.8% (p<0.01) , インスリン6.1% (p<0.05) であった。以上の結果, 希少糖含有シロップはショ糖に比べ血糖応答およびインスリン値の上昇が低い低GI甘味料であることが示された。低用量単回試験は倫理委員会の承認後, 臨床試験登録システムUMIN-CTRに登録し実施した (UMIN000018120) 。