著者
山田 幸樹 金野 倫子 内山 真
出版者
日本大学医学会
雑誌
日大医学雑誌 (ISSN:00290424)
巻号頁・発行日
vol.72, no.3, pp.137-141, 2013-06-01 (Released:2014-12-20)
参考文献数
13

Gender identity disorder (GID) is defined as a sexual disorder characterized by strong self-identification with the opposite gender, followed by unpleasant feelings due to the birth-given gender. This paper examines the current diagnostic criteria and treatment for GID. While the etiology of GID remains unknown, several hypotheses have been proposed. We describe the evolution of the hypotheses on the etiology of GID. The possible biological pathogenesis of GID is also discussed mainly from the viewpoint of brain science. Similar to animal studies, it has been reported that fetal or neonatal gonadal steroids are responsible for sexual differentiation of the human brain, which might be related to gender identity and sexual orientation. Based upon the findings of investigations into the biological basis of GID, valuable insights into GID are suggested.
著者
山田 幸樹 金野 倫子 内山 真
出版者
NIHON UNIVERSITY MEDICAL ASSOCIATION
雑誌
日大醫學雜誌 (ISSN:00290424)
巻号頁・発行日
vol.72, no.3, pp.137-141, 2013-06-01

Gender identity disorder (GID) is defined as a sexual disorder characterized by strong self-identification with the opposite gender, followed by unpleasant feelings due to the birth-given gender. This paper examines the current diagnostic criteria and treatment for GID. While the etiology of GID remains unknown, several hypotheses have been proposed. We describe the evolution of the hypotheses on the etiology of GID. The possible biological pathogenesis of GID is also discussed mainly from the viewpoint of brain science. Similar to animal studies, it has been reported that fetal or neonatal gonadal steroids are responsible for sexual differentiation of the human brain, which might be related to gender identity and sexual orientation. Based upon the findings of investigations into the biological basis of GID, valuable insights into GID are suggested.
著者
山田 幸樹 金野 倫子 内山 真
出版者
NIHON UNIVERSITY MEDICAL ASSOCIATION
雑誌
日大醫學雜誌 (ISSN:00290424)
巻号頁・発行日
vol.72, no.3, pp.137-141, 2013-06-01
参考文献数
13

Gender identity disorder (GID) is defined as a sexual disorder characterized by strong self-identification with the opposite gender, followed by unpleasant feelings due to the birth-given gender. This paper examines the current diagnostic criteria and treatment for GID. While the etiology of GID remains unknown, several hypotheses have been proposed. We describe the evolution of the hypotheses on the etiology of GID. The possible biological pathogenesis of GID is also discussed mainly from the viewpoint of brain science. Similar to animal studies, it has been reported that fetal or neonatal gonadal steroids are responsible for sexual differentiation of the human brain, which might be related to gender identity and sexual orientation. Based upon the findings of investigations into the biological basis of GID, valuable insights into GID are suggested.
著者
横瀬 宏美 鈴木 正泰 金野 倫子 高橋 栄 石原 金由 土井 由利子 内山 真
出版者
一般社団法人 日本女性心身医学会
雑誌
女性心身医学
巻号頁・発行日
vol.19, no.3, pp.310-321, 2015

背景:月経前不快気分障害(premenstrual dysphoric disorder:以下PMDD)は,黄体期後期に抑うつ症状が出現し,仕事や学業,対人関係などにおける生活上の問題をきたす病態である.PMDDは月経のある女性の3〜8%にみられ,様々な研究が行われてきたが詳細な病態生理学的機序については不明な点が多い.方法:一女子大学において,ある年度に心理学の講義を履修した学生に研究参加を呼びかけ,833名(有効回答率93%)からデータを得た.調査は自記式で行い,調査用紙には 1)月経前不快気分障害診断に関する項目,2)生活習慣,睡眠習慣,朝型・夜型の時間特性などに関する要因,3)月経の状態,婦人科受診歴などの婦人科的要因,4)精神科受診歴および家族歴,性格特性,季節性特徴などの精神医学的要因,5)最近1年間のライフイベント,ストレス対処行動などストレス関連要因,という内容を含めた.PMDDの診断は,精神疾患の診断・統計マニュアル新訂版(DSM-IV-TR)に基づいて行い,PMDDと個々の要因との関連について統計学的に検討した.結果:PMDDは833名中45名(5.4%)にみられた.PMDDの有無を従属変数とし,合計30の要因との間で単変量ロジスティック回帰分析を行ったところ,合計16の有意な関連要因がみいだされた.これら有意な関連要因間の交絡関係を調整するため多変量ロジスティック回帰分析を行ったところ,神経質,身体的不調への過敏,家族との問題,ストレス対処行動としての飲酒がPMDDと有意な正の関連を示した.結語:今回の調査で得られたPMDDの有病率は5.4%と,先行研究における有病率とほぼ同等であった.本研究の結果から,PMDDにはうつ病と共通する性格素因や心理的ストレスなど,精神医学的および心理的要因が強く関与していることが示唆された.