著者

Masahiro Iwakura Masahiko Wakasa Kazuki Okura Atsuyoshi Kawagoshi Keiyu Sugawara Hitomi Takahashi Takanobu Shioya

出版者

The Japanese Association of Rehabilitation Medicine

雑誌

Progress in Rehabilitation Medicine (ISSN:24321354)

巻号頁・発行日

vol.6, pp.20210008, 2021 (Released:2021-02-06)

参考文献数

29

被引用文献数

2

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Objectives: We aimed to identify the quadriceps muscle strength (QMS) thresholds below which exercise capacity is compromised in men with chronic obstructive pulmonary disease (COPD).Methods: We measured the quadriceps isometric maximum voluntary contraction (QMVC) and calculated the QMVC values normalized to weight (QMVC-BW), height squared (QMVC-H2), and body mass index (QMVC-BMI) in 113 patients with COPD. The functional exercise capacity was evaluated using the 6-minute walk distance (6MWD), and 6MWD <350 m was defined as functional exercise intolerance. Thresholds were determined for QMVC and its normalized values to achieve high specificity (>0.90) with maximal sensitivity. P-values <0.01 were considered statistically significant.Results: Data from 99 male patients (age, 74 ± 6 years; percentages of predicted forced expiratory volume in 1-s, 56.9 ± 26.4%) were analyzed; 3 women and 11 participants with the missing data were excluded. Multivariate logistic regression models identified significant associations of QMVC and QMVC-H2 with 6MWD, after adjustment for age and dyspnea. C-statistics showed that the area under the curves of all QMVC parameters were comparable. The thresholds of QMVC and QMVC-H2 for predicting compromised exercise capacity were 26.2 kg and 9.6 kg/m2, respectively.Conclusions: QMS thresholds in men with COPD could help clinicians evaluate whether QMS is insufficient to achieve 6MWD ≥350 m and thereby identify patients who should be specifically targeted for muscle strengthening training during their pulmonary rehabilitation program.

著者

Masahiro IWAKURA Kazuki OKURA Mika KUBOTA Keiyu SUGAWARA Atsuyoshi KAWAGOSHI Hitomi TAKAHASHI Takanobu SHIOYA

出版者

Japanese Society of Physical Therapy

雑誌

Physical Therapy Research (ISSN:21898448)

巻号頁・発行日

vol.24, no.1, pp.35-42, 2021-04-20 (Released:2021-04-20)

参考文献数

33

被引用文献数

1 21

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Objective: To estimate the minimal clinically important difference (MCID) of quadriceps and inspiratory muscle strength after a home-based pulmonary rehabilitation program (PRP) in chronic obstructive pulmonary disease (COPD). Method: Eighty-five COPD patients were included. Quadriceps maximal voluntary contraction (QMVC) was measured. We measured maximal inspiratory mouth pressure (PImax), the 6-minute walk distance (6MWD), the chronic respiratory questionnaire (CRQ) and the modified Medical Research Council dyspnoea score (mMRC). All measurements were conducted at baseline and at the end of the PRP. The MCID was calculated using anchor-based (using 6MWD, CRQ, and mMRC as possible anchor variables) and distribution-based (half standard deviation and 1.96 standard error of measurement) approaches. Changes in the five variables were compared in patients with and without changes in QMVC or PImax >MCID for each variable. Results: Sixty-nine COPD patients (age 75±6 years) were analysed. QMVC improved by 2.4 (95%CI 1.1-3.7) kgf, PImax by 5.8 (2.7-8.8) cmH2O, 6MWD by 21 (11-32) meters and CRQ by 3.9 (1.6-6.3) points. The MCID of QMVC and PImax was 3.3-7.5 kgf and 17.2-17.6 cmH2O, respectively. The MCID of QMVC (3.3 kgf) could differentiate individuals with significant improvement in 6MWD and PImax from those without. Conclusion: The MCID of QMVC (3.3 kgf) can identify a meaningful change in quadriceps muscle strength after a PRP. The MCID of PImax (17.2 cmH2O) should be used with careful consideration, because the value is estimated using distributionbased method.

著者

高橋 ひとみ Hitomi Takahashi 桃山学院大学法学部

出版者

桃山学院大学総合研究所

雑誌

桃山学院大学総合研究所紀要 = ST.ANDREW'S UNIVERSITY BULLETIN OF THE RESEARCH INSTITUTE (ISSN:1346048X)

巻号頁・発行日

vol.30, no.2, pp.1-11, 2004-12-20

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Many children in Japan today do not know how to grasp a pencil or use chopsticks properly. Improper pencil grasp and chopstick usage may have a negative impact on one's studying and eating posture. In addition, improper posture potentially leads to poor eyesight. This survey was conducted to examine how pencil grasp and chopstick usage may affect the seated posture among children with the aim of putting a stop to the increasing number of children with poor eyesight. Of all the children surveyed, approximately 30% improperly grasped pencils while approximately 25% improperly used chopsticks. The survey result shows that pencil grasp and chopstick usage are associated with studying (seated) posture. By means of proper pencil grasp and chopstick usage, children were more likely to maintain a distance of 30 cm or more between the eyes and the notebook surface. This is known to impose minimal strain to the eyes. In fact, those children who maintained this optimal posture were less likely to have poor eyesight compared to those who did not. In view of these facts, encouraging efficient pencil grasp and proper chopstick usage among children will contribute to promoting the optimal studying posture that imposes minimal strain on the eyes. Until children are old enough to understand what needs to be done to maintain good eyesight, parents and adults should provide necessary care and support in this respect.

著者

Hitomi Takahashi Yutaka Kodama

出版者

Japanese Society for Plant Biotechnology

雑誌

Plant Biotechnology (ISSN:13424580)

巻号頁・発行日

vol.38, no.4, pp.449-452, 2021-12-25 (Released:2021-12-25)

参考文献数

7

被引用文献数

1

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Ongoing research has generated many important lines of the model liverwort Marchantia polymorpha, including mutants and transgenic lines. To maintain these lines, researchers typically spend a lot of time and effort periodically replanting thalli (e.g., every month). To avoid this routine maintenance, researchers have developed methods for cryopreservation of dried and frozen gemmae. In this study, we developed a culture-based method for preserving gemmalings and thalli without encapsulation, drying, or freezing. The method requires only tissue culture on agar medium supplemented with sucrose in the dark at regular temperature (22°C). These culture conditions severely inhibit growth of gemmalings and thalli; however, these tissues remained alive after more than 1 year of storage. Survival rate of tissues using this method was 100% in all tests. This method thus enables preservation of gemmaling and thallus cultures on medium under regular temperature conditions, thereby relieving researchers of labor-intensive routine maintenance.

著者

Hitomi Takahashi Yutaka Kodama

出版者

Japanese Society for Plant Biotechnology

雑誌

Plant Biotechnology (ISSN:13424580)

巻号頁・発行日

pp.21.0902a, (Released:2021-12-14)

参考文献数

7

被引用文献数

1

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Ongoing research has generated many important lines of the model liverwort Marchantia polymorpha, including mutants and transgenic lines. To maintain these lines, researchers typically spend a lot of time and effort periodically replanting thalli (e.g., every month). To avoid this routine maintenance, researchers have developed methods for cryopreservation of dried and frozen gemmae. In this study, we developed a culture-based method for preserving gemmalings and thalli without encapsulation, drying, or freezing. The method requires only tissue culture on agar medium supplemented with sucrose in the dark at regular temperature (22°C). These culture conditions severely inhibit growth of gemmalings and thalli; however, these tissues remained alive after more than 1 year of storage. Survival rate of tissues using this method was 100% in all tests. This method thus enables preservation of gemmaling and thallus cultures on medium under regular temperature conditions, thereby relieving researchers of labor-intensive routine maintenance.

著者

Atsuyoshi Kawagoshi Masahiro Iwakura Yutaka Furukawa Keiyu Sugawara Hitomi Takahashi Takanobu Shioya

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.32, no.12, pp.804-809, 2020 (Released:2020-12-11)

参考文献数

30

被引用文献数

1

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[Purpose] The effect of physical activity on systemic inflammation remains unclear and might be negative in patients with chronic obstructive pulmonary disease (COPD) and lower weight. We investigated the amount of physical activity as the time spent in posture and movement and its association with systemic inflammation. [Participants and Methods] In this retrospective cross-sectional pilot study, we evaluated 11 patients with COPD (age, 73 ± 7 years; body mass index, 18.9 ± 2.9 kg/m2). A recently developed triaxial accelerometer was used to measure the time spent in posture and movement. We also evaluated body composition, physiological indexes, and serum levels of inflammatory cytokines. Single correlation coefficients were calculated as the association between physical activity and other outcomes. [Results] The walking time was 36 ± 32 min/d, and the standing time was 151 ± 118 min/d. The time spent walking significantly correlated with the fat-free mass index (r=0.73) and interleukin (IL)-8 level (r=0.76). The time spent standing significantly correlated with the C-reactive protein (r=0.80) and IL-6 levels (r=0.74). [Conclusion] These data indicate that increased physical activity is associated with higher systematic inflammation. We should consider that the systemic inflammation may have been affected by the increased physical activity of the patients with COPD and lower weight in this study.

著者

北條 達也 井口 順太 高橋 仁美 小川 博之 Tatsuya Hojo Junta Iguchi Hitomi Takahashi Hiroyuki Ogawa

出版者

同志社大学スポーツ健康科学会

雑誌

同志社スポーツ健康科学 = Doshisha Journal of Health and Sports Science (ISSN:18834132)

巻号頁・発行日

no.4, pp.51-55, 2012-03-01

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肋骨の疲労骨折は,ゴルフなどで生じる中位から下位の肋骨骨折がよく知られているが,第一肋骨の疲労骨折の報告は比較的少ない。われわれは,大学生チアリーダーに発生した第一肋骨の疲労骨折を経験した。左肩甲部痛で発症し,さらに左上肢尺側のしびれと痛みを自覚した。安静および低出力パルス超音波治療によって加療するも骨癒合は得られなかったが,1年後には競技に復帰できた。X線検査では評価が困難な同部位の評価に3DCTは,有用であった。

著者

Masahiro IWAKURA Kazuki OKURA Mika KUBOTA Keiyu SUGAWARA Atsuyoshi KAWAGOSHI Hitomi TAKAHASHI Takanobu SHIOYA

出版者

Japanese Society of Physical Therapy

雑誌

Physical Therapy Research (ISSN:21898448)

巻号頁・発行日

pp.E10049, (Released:2020-10-12)

参考文献数

33

被引用文献数

21

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Objective: To estimate the minimal clinically important difference (MCID) of quadriceps and inspiratory muscle strength after a home-based pulmonary rehabilitation program (PRP) in chronic obstructive pulmonary disease (COPD). Method: Eighty-five COPD patients were included. Quadriceps maximal voluntary contraction (QMVC) was measured. We measured maximal inspiratory mouth pressure (PImax), the 6-minute walk distance (6MWD), the chronic respiratory questionnaire (CRQ) and the modified Medical Research Council dyspnoea score (mMRC). All measurements were conducted at baseline and at the end of the PRP. The MCID was calculated using anchor-based (using 6MWD, CRQ, and mMRC as possible anchor variables) and distribution-based (half standard deviation and 1.96 standard error of measurement) approaches. Changes in the five variables were compared in patients with and without changes in QMVC or PImax >MCID for each variable. Results: Sixty-nine COPD patients (age 75±6 years) were analysed. QMVC improved by 2.4 (95%CI 1.1-3.7) kgf, PImax by 5.8 (2.7-8.8) cmH2O, 6MWD by 21 (11-32) meters and CRQ by 3.9 (1.6-6.3) points. The MCID of QMVC and PImax was 3.3-7.5 kgf and 17.2-17.6 cmH2O, respectively. The MCID of QMVC (3.3 kgf) could differentiate individuals with significant improvement in 6MWD and PImax from those without. Conclusion: The MCID of QMVC (3.3 kgf) can identify a meaningful change in quadriceps muscle strength after a PRP. The MCID of PImax (17.2 cmH2O) should be used with careful consideration, because the value is estimated using distributionbased method.

著者

高橋 ひとみ 衞藤 隆 Hitomi Takahashi Takashi Eto 桃山学院大学法学部 東京大学教育学研究科

雑誌

桃山学院大学人間科学 = HUMAN SCIENCES REVIEW, St. Andrew's University (ISSN:09170227)

巻号頁・発行日

no.37, pp.35-61, 2009-10-20

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In February 2009, we tested the far-vision visual acuity and near-vision visual acuity of school children at "A" elementary school, a municipal school. The purpose of the test was to examine whether the present far visual acuity test could also identify the children whose near visual acuity is bad. Based on the past study, we set the standard of near visual acuity at 0.8. We recommended that children whose near visual acuity was under0.8 see an ophthalmologist. There were many children whose far visual acuity was under 1.0, more than half of all children, especially in the upper grades. This result shows that there is concern with the control of children's eyesight after the test.On the other hand, more than ten percent of the children of each grade scored less than 0.8 in uncorrected vision. We found children who have trouble seeing near objects who are overlooked in the present far visual acuity test. We have to check children's near visual acuity in order to find children who have trouble with near visual acuity.