著者

Akane Tsuruta Tian Zheng Mari Ogura Masayuki Yagi Wakako Takabe Yoshikazu Yonei

出版者

Society for Glycative Stress Research

雑誌

Glycative Stress Research (ISSN:21883602)

巻号頁・発行日

vol.6, no.1, pp.39-48, 2019 (Released:2019-05-31)

著者

鶴田 涼子 Tsuruta Ryoko

出版者

三重大学人文学部文化学科

雑誌

人文論叢 = Bulletin of the Faculty of Humanities and Social Sciences, Department of Humanities : 三重大学人文学部文化学科研究紀要 (ISSN:02897253)

巻号頁・発行日

no.36, pp.45-55, 2019

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『子どもと家庭のためのメルヒェン集』Kinder- und Hausmärchen gesammelt durch die Brüder Grimmの「踊って擦り切れた靴」Die zertanzten Schuheは、『国際昔話話型カタログ分類と文献目録』のATU306番「踊って擦り切れた靴」(The Danced-out Shoes)に分類される。類話である『ハンガリー民話集』の「靴をはきつぶす王女たち」と『ハンガリーの伝説』の「12人の踊り姫」との比較を行うことで、グリム・メルヒェン「踊って擦り切れた靴」に描かれていない、もしくは伝承される間に変化した物語の背景を知ることができる。姫たちが結ばれることを願う王子たちの過去については、『ハンガリーの伝説』を参考にすることにより、伝承過程で失われたであろう物語の空隙を埋めることが可能となる。また、「踊って擦り切れた靴」においては、タイトルが変更されたことで民話の解釈に新たな可能性が付与されたと考えることができる。

著者

鶴田 智 Tsuruta Satoshi ツルタ サトシ

出版者

大阪大学大学院 人間科学研究科 対人社会心理学研究室

雑誌

対人社会心理学研究 = Japanese journal of interpersonal and social psychology (ISSN:13462857)

巻号頁・発行日

no.18, pp.173-178, 2018-03

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資料近年、インターネットやSNS上で犯罪者を誹謗中傷するなど、誰でも容易に社会的制裁を行うことができるようになった。社会的制裁とは犯罪者への非法的な制裁行為とされ、犯罪者の社会復帰の妨げとして問題視されている。法制度上の刑罰があるにも関わらず、なぜ社会的制裁が起きるのか。先行研究によれば、法的制裁(刑罰)と社会的制裁には相補的な関係性があり、法的制裁が社会的制裁を促進(または抑制する)可能性がある。本研究は、刑事事件の犯罪者に対する法的制裁と社会的制裁の相補性の検証を目的とした2つの実験を行った。その結果、客観的指標(社会的制裁の強さ、法的制裁の重さ)の影響による法的制裁と社会的制裁の相補性は確認されなかったが、主観的評価(社会的制裁の強さ認知、刑の重さ認知)において、法的制裁と社会的制裁の相補性の存在が示唆された。よって、人々の主観的評価に影響を及ぼす事で、客観的な法的制裁と社会的制裁の相補性を実現できると考えられる。社会的制裁が引き起こす問題を解決するために、今後は人々の主観的評価に影響を及ぼす要因を検討する必要がある。

著者

Nobuyuki Katsumata Daisuke Harama Takako Toda Yuto Sunaga Masashi Yoshizawa Yosuke Kono Yohei Hasebe Keiichi Koizumi Minako Hoshiai Tomohiro Saito Sho Hokibara Koji Kobayashi Miwa Goto Tomoaki Sano Makoto Tsuruta Makoto Nakamura Sonoko Mizorogi Masanori Ohta Mie Mochizuki Hiroki Sato Hiroshi Yokomichi Takeshi Inukai

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.31, no.11, pp.573-580, 2021-11-05 (Released:2021-11-05)

参考文献数

42

被引用文献数

9

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Background: Kawasaki disease is suspected to be triggered by previous infection. The prevention measures for coronavirus disease 2019 (COVID-19) have reportedly reduced transmission of certain infectious diseases. Under these circumstances, the prevention measures for COVID-19 may reduce the incidence of Kawasaki disease.Methods: We conducted a retrospective study using registration datasets of patients with Kawasaki disease who were diagnosed in all 11 inpatient pediatric facilities in Yamanashi Prefecture. The eligible cases were 595 cases that were diagnosed before the COVID-19 pandemic (from January 2015 through February 2020) and 38 cases that were diagnosed during the COVID-19 pandemic (from March through November 2020). Incidence of several infectious disease were evaluated using data from the Infectious Disease Weekly Report conducted by the National Institute of Infectious Diseases.Results: Epidemics of various infectious diseases generally remained at low levels during the first 9 months (March through November 2020) of the COVID-19 pandemic. Moreover, the incidence of COVID-19 was 50–80 times lower than the incidence in European countries and the United States. The total number of 38 cases with Kawasaki disease for the 9 months during the COVID-19 pandemic was 46.3% (−3.5 standard deviations [SDs] of the average [82.0; SD, 12.7 cases] for the corresponding 9 months of the previous 5 years. None of the 38 cases was determined to be triggered by COVID-19 based on their medical histories and negative results of severe acute respiratory syndrome coronavirus 2 testing at admission.Conclusion: These observations provide a new epidemiological evidence for the notion that Kawasaki disease is triggered by major infectious diseases in children.

著者

鶴田 尚美 TSURUTA Naomi

出版者

京都女子大学現代社会学部

雑誌

現代社会研究 (ISSN:18842623)

巻号頁・発行日

vol.16, pp.55-65, 2013-12

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通常わたしたちは、死は人生において最大の悪だと考えており、短い生よりも長い生の方がよりよいと思っている。それでは、不老不死であったとしたなら、わたしたちの人生はよりよいものになるのだろうか。バーナード・ウィリアムズは、不死は本人にとって望ましいものではなく、不死の人間は必然的に人生に退屈すると論じている。本稿は、ウィリアムズの主張の根底にある人格概念をデレク・パーフィットの還元主義的人格概念と比較しつつ、ウィリアムズの議論を批判的に検討する。In 'The Makropulos case: reflections on tedium of immortality', Bernard Williams argued as follows: if death is a misfortune and a longer life is better than a shorter life, then death at any time is evil, and it is better to live than die. Then, it would be not only always better to live but also better to live always, that is, never die. However, an endless life must be meaningless, and we have no reason to want to live till eternity, because eternal life must be a life which is intolerably boring. According to Williams, a person has a certain character and his/her own conception of life and integrity, which is important for us as persons. In contrast, Derek Parfit suggests that personal identity in itself is not important. According to his 'reductionism' account, what really matters to us is not personal identity, but psychological connectedness or continuity (relation R) over time. In this paper, I will examine Williams' supposition that a person must have a fixed character, and then criticize his explanation that an immortal person necessary fails to boredom. Next, I will explain Parfit's theory of personal identity and point out that what matters in my survival is not identity over time, but relation R. Finally, I will conclude that Parfit's concept of person is more plausible to apply to our real human lives.

著者

鶴田 雅昭 Tsuruta Masaaki ツルタ マサアキ

出版者

大阪大学経済学会

雑誌

大阪大学経済学 (ISSN:04734548)

巻号頁・発行日

vol.64, no.2, pp.32-44, 2014-09

著者

Takanori Miyoshi Nobuhiro Misumi Mikako Hiraike Yuki Mihara Takashi Nishino Minako Tsuruta Yosei Kawamata Yoichi Hiraki Aki Kozono Masao Ichiki

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.39, no.12, pp.2009-2014, 2016-12-01 (Released:2016-12-01)

参考文献数

42

被引用文献数

21

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Cisplatin (CDDP) combination chemotherapy is widely administered to patients with advanced lung cancer. The dose depends on multiple factors, including whether the tumor is non-small-cell lung cancer (NSCLC) or small-cell lung cancer (SCLC). Although efficacy is limited by cisplatin-induced nephrotoxicity (CIN), little is known about the risk factors for this complication. The aim of this study was to identify the risk factors for CIN in patients with advanced lung cancer, both NSCLC and SCLC. We retrospectively reviewed clinical data for 148 patients who underwent initial chemotherapy including CDDP ≥50 mg/m2 per patient per day for the first course at Kyushu Medical Center between October 2010 and September 2013. All data were collected from the electronic medical record system. Nephrotoxicity was defined as an increase in serum creatinine concentration of at least grade 2 during the first course of CDDP chemotherapy, as described by the National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0. CIN was observed in nine patients. Univariate analysis revealed that cardiac disease and lower baseline serum albumin (Alb) values conferred a higher risk of nephrotoxicity (p<0.05). The cut-off value of Alb was 3.8 g/dL, calculated by receiver operating characteristics (ROC) curves. Multivariable logistic regression analysis revealed that cardiac disease (odds ratio=11.7; p=0.002) and hypoalbuminemia (odds ratio=6.99 p=0.025 significantly correlated with nephrotoxicity. In conclusion, cardiac disease and low baseline Alb values are possible risk factors for CIN.

著者

Haruo Tsuruta Yasuji Oura Mitsuru Ebihara Yuichi Moriguchi Toshimasa Ohara Teruyuki Nakajima

出版者

GEOCHEMICAL SOCIETY OF JAPAN

雑誌

GEOCHEMICAL JOURNAL (ISSN:00167002)

巻号頁・発行日

vol.52, no.2, pp.103-121, 2018-03-30 (Released:2018-04-19)

参考文献数

35

被引用文献数

42

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Using an hourly-resolution time series of the Fukushima radionuclides collected on used filter-tapes installed in suspended particulate matter (SPM) monitors, we measured the hourly radiocesium values at the SPM monitoring sites of Futaba and Naraha located within 20 km of the Fukushima Daiichi Nuclear Power Plant (FD1NPP) during March 12–25, 2011. The time-series of the 137Cs concentrations at the sites were analyzed and compared with radiation dose rates at the many monitoring posts/points of Fukushima Prefecture and the Tokyo Electric Power Company. At Futaba, nine plumes of high 137Cs concentrations were found on March 12–13, 15–16, 18–20, and 24–25, 2011, when southeasterly winds prevailed. On March 12, the first peak of the 137Cs concentrations was detected at Futaba at 9:00 Japanese Standard Time (JST) due to the first release from reactor Unit 1 (U1) in the early morning. Furthermore, the highest 137Cs concentration, i.e., 13,600 Bq m–3 was observed at 15:00 JST after a vent operation at U1, just before the hydrogen explosion of U1 at 15:36 JST. On the afternoon of March 15, plumes from the FD1NPP were observed at Futaba due to a constant southeasterly wind and were then transported to downwind, resulting in the formation of a highly deposited zone of radionuclides spanning more than 30 km from near the FD1NPP to the northwest. In contrast, seven plumes of high 137Cs concentrations were found at Naraha on March 15–16, 18, 20–21, 2011, when northerly winds prevailed. On March 15, a plume caused by the first release from Unit 2 was observed at Naraha at 1:00 JST, and the highest concentration, i.e., 8,300 Bq m–3, was observed at 3:00 JST, and then were transported southward to the Kantou area. The activity ratios of 134Cs/137Cs in the plumes were divided into two groups. The plumes at Futaba on March 12–13, which had ratios of 0.92–0.94, are identified to be released from U1, compared to its ratio of 0.94, as derived from the inventory data. All other plumes with the ratios of 1.02–1.04 at Futaba and Naraha during March 15–21 have not been determined to be released from U2 and/or Unit 3.

著者

Masako YAJIMA Shin-Ichiro KARAKI Takeshi TSURUTA Shunsuke KIMURA Junko NIO-KOBAYASHI Atsukazu KUWAHARA Takaji YAJIMA

出版者

バイオメディカルリサーチプレス

雑誌

Biomedical Research (ISSN:03886107)

巻号頁・発行日

vol.37, no.5, pp.319-328, 2016-10-01 (Released:2016-10-25)

参考文献数

41

被引用文献数

13

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Non-neuronal and atropine-sensitive ileal contractile responses to short chain fatty acids (SCFAs) are detected in the neonatal stage, and change with age or inflammatory conditions. However, the roles of luminal SCFAs in developmental changes have not yet been elucidated. We examined ileal contractile responses to SCFAs in mice colonized with different SCFA-producing intestinal microbiota under normal and inflammatory conditions. Using conventional (Conv), germ-free (GF), and gnotobiotic mice infected with Bifidobacterium (GB-bif), Propionibacterium (GB-prop), or Lactobacillus (GB-lact), ileal contractions were measured in 1-day-old neonates and 7-week-old mice using an isotonic transducer. Contractions occurred in all 1-day-old neonates, and were significantly desensitized in the adult stage in the Conv, GB-bif, and GB-prop groups, but not in the GF and GB-lact groups. An injection of lipopolysaccharide frequently restored desensitized contractions; however, the contraction rate did not change in the GF and GB-lact groups. The relative mRNA expression of a SCFA receptor (GPR43) or nicotinic acetylcholine receptor α7 was weaker in the GF group (0.3-fold or 0.4-fold expression level, respectively) than in the Conv group. In conclusion, the luminal inhabitation of SCFA-producing bacteria may potentiate the regulation of non-neuronal and atropine-sensitive ileal contractile responses to SCFAs under healthy and inflammatory conditions.

著者

Yudai Takarada Tomomi Tsuruta Naokata Ishii

出版者

日本生理学会

雑誌

The Japanese Journal of Physiology (ISSN:0021521X)

巻号頁・発行日

vol.54, no.6, pp.585-592, 2004 (Released:2005-03-12)

参考文献数

36

被引用文献数

56 120

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To obtain insight into the relative contributions of exercise and occlusive stimuli to these muscular adaptations, the present study investigated the short- and long-term effects of varied combinations of low- intensity exercise and vascular occlusion. The subjects were separated into 3 groups (n = 6 for each group): low- intensity with vascular occlusion (LIO), low-intensity without vascular occlusion (LI), and vascular occlusion without exercise (VO). LIO and LI groups performed bilateral knee extension exercises in seated positions with an isotonic extension machine. In the LIO group, both sides of the thigh were pressure-occluded at the proximal end by means of a tourniquet during the entire session of exercise (˜10 min), whereas only the occlusion with the same pressure and duration was given in the VO group. The mean occlusion pressure was 218 ± 8.1 mmHg (mean ± SE). The exercise session consisted of five sets of exercise at an intensity of 10-20% 1RM and was performed twice a week for 8 wk. After the period of exercise training, isometric and isokinetic strengths at all velocities examined increased significantly in the LIO group (p < 0.05), whereas no significant change in strength was seen in the LI and VO groups. The increase in muscular strength in LIO was associated with a significant increase in the cross-sectional area of knee extensor muscles by 10.3 ± 1.6%. The plasma growth hormone concentration measured 15 min after the session of exercise showed a marked increase only in LIO. The results showed that the low-intensity exercise and occlusive stimuli have cooperative effects in the long-term adaptation of muscle and an acute response to growth hormone.

著者

Mitsue Ishisaka Kenichi Kakefuda Mika Yamauchi Kazuhiro Tsuruma Masamitsu Shimazawa Akifumi Tsuruta Hideaki Hara

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.34, no.9, pp.1481-1486, 2011-09-01 (Released:2011-09-01)

参考文献数

34

被引用文献数

18 71

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Depression is a significant public health problem and some reports indicate an association between depression and endoplasmic reticulum stress. Luteolin is a flavonoid contained in many plants and with a variety of known pharmacological properties such as anti-inflammatory, anti-anxiety, and memory-improving effects, suggesting that luteolin penetrates into the brain. In the present study, we investigated the effects of luteolin on endoplasmic reticulum stress-induced neuronal cell death. Luteolin significantly suppressed tunicamycin-induced cell death at 1 to 10 μM in human neuroblastoma cells. Luteolin increased in the expression of the 78 kDa glucose-regulated protein and 94 kDa glucose-regulated protein and decreased in the cleavage activation of caspase-3. Additionally, to investigate whether chronic luteolin treatment has an antidepression effect, we performed some behavioral tests. Chronic luteolin treatment showed antidepressant-like effects in behavioral tests and, luteolin attenuated the expression of endoplasmic reticulum stress-related proteins in the hippocampus of corticosterone-treated depression model mice. These findings indicate that luteolin has antidepressant-like effects, partly due to the suppression of endoplasmic reticulum stress.

著者

Yoshinobu Tsuruta Yushi Katsuyama Yuri Okano Toshiyuki Ozawa Satoshi Yoshimoto Hideya Ando Hitoshi Masaki Masamitsu Ichihashi

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.46, no.5, pp.725-729, 2023-05-01 (Released:2023-05-01)

参考文献数

28

被引用文献数

3

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Epidermal keratinocytes protect themselves by cooperating with neighboring cells against internal and external stresses, which leads not only to the maintenance of cell homeostasis but also to the prevention of skin aging. Although it is known that nuclear factor (NF)-E2-related factor 2 (Nrf2) signaling plays a pivotal role in ameliorating oxidative stress and inflammatory responses under stress situations, it is unclear whether Nrf2 signaling in keratinocytes cooperates with neighboring cells such as dermal fibroblasts. Thus, this study was conducted to examine the influence of dermal fibroblasts on Nrf2 signaling in epidermal keratinocytes using a co-culture system. The results show that expression levels of Nrf2-regulated antioxidant factors, such as glutathione and heme oxygenase-1, in HaCaT keratinocytes (HaCaT KCs) are up-regulated in the presence of normal human dermal fibroblasts (NHDFs). In addition, the secretion of pro-inflammatory molecules, including interleukin-1α (IL-1α) and prostaglandin E2 (PGE2), is suppressed in co-cultures of NHDFs and UVB-irradiated HaCaT KCs. Interestingly, the localization of Nrf2 protein in HaCaT KCs was immediately translocated from the cytoplasm to the nucleus after the co-culture with NHDFs. These results suggest the possibility that Nrf2 signaling in keratinocytes is regulated in cooperation with dermal fibroblasts.

著者

鶴田 達成 Tatsunari Tsuruta

雑誌

紀要 = Journal of Kyoritsu Women's Junior College

巻号頁・発行日

vol.61, pp.1-10, 2018-01

著者

Takao KOISO Yoji KOMATSU Daisuke WATANABE Go IKEDA Hisayuki HOSOO Masayuki SATO Yoshiro ITO Tomoji TAKIGAWA Mikito HAYAKAWA Aiki MARUSHIMA Wataro TSURUTA Noriyuki KATO Kazuya UEMURA Kensuke SUZUKI Akio HYODO Eichi ISHIKAWA Yuji MATSUMARU

出版者

The Japan Neurosurgical Society

雑誌

Neurologia medico-chirurgica (ISSN:04708105)

巻号頁・発行日

pp.2022-0253, (Released:2023-01-05)

参考文献数

15

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The influence of aneurysm size on the outcomes of endovascular management (EM) for aneurysmal subarachnoid hemorrhages (aSAH) is poorly understood. To evaluate the outcomes of EM for ruptured large cerebral aneurysms, we retrospectively analyzed the medical records of patients with aSAH that were treated with coiling between 2013 and 2020 and compared the differences in outcomes depending on aneurysm size. A total of 469 patients with aSAH were included; 73 patients had aneurysms measuring ≥10 mm in diameter (group L), and 396 had aneurysms measuring <10 mm in diameter (group S). The median age; the percentage of patients that were classified as World Federation of Neurological Surgeons grade 1, 2, or 3; and the frequency of intracerebral hemorrhages differed significantly between group L and group S (p = 0.0105, p = 0.0075, and p = 0.0458, respectively). There were no significant differences in the frequencies of periprocedural hemorrhagic or ischemic events. Conversely, rebleeding after the initial treatment was significantly more common in group L than in group S (6.8% vs. 2.0%; p = 0.0372). The frequency of a modified Rankin Scale score of 0-2 at discharge was significantly lower (p = 0.0012) and the mortality rate was significantly higher (p = 0.0023) in group L than in group S. After propensity-score matching, there were no significant differences in complications and outcomes between the two groups. Rebleeding was more common in large aneurysm cases. However, propensity-score matching indicated that the outcomes of EM for aSAH may not be affected markedly by aneurysm size.

著者

鶴田 真紀 ツルタ マキ Maki Tsuruta

雑誌

立教大学教育学科研究年報

巻号頁・発行日

vol.54, pp.51-62, 2011-03-15

著者

K. Tsuruta

出版者

THE PHYSICAL SOCIETY OF JAPAN , The Mathematical Society of Japan

雑誌

Tokyo Sugaku-Butsurigaku Kwai Kiji (ISSN:21852669)

巻号頁・発行日

vol.8, no.4, pp.135-151, 1896 (Released:2010-03-16)

参考文献数

7

著者

K. Tsuruta

出版者

THE PHYSICAL SOCIETY OF JAPAN , The Mathematical Society of Japan

雑誌

Tokyo Sugaku-Butsurigaku Kwai Kiji (ISSN:21852669)

巻号頁・発行日

vol.8, no.4, pp.153-161, 1896 (Released:2010-03-16)

参考文献数

3

著者

K. Tsuruta

出版者

THE PHYSICAL SOCIETY OF JAPAN , The Mathematical Society of Japan

雑誌

Tokyo Sugaku-Butsurigaku Kwai Kiji (ISSN:21852669)

巻号頁・発行日

vol.7, no.6, pp.118-122_1, 1896 (Released:2010-03-16)

参考文献数

2

著者

K. Tsuruta

出版者

THE PHYSICAL SOCIETY OF JAPAN , The Mathematical Society of Japan

雑誌

Tokyo Sugaku-Butsurigaku Kwai Kiji (ISSN:21852669)

巻号頁・発行日

vol.7, no.4, pp.57-59, 1896 (Released:2010-03-16)

著者

K. Tsuruta

出版者

THE PHYSICAL SOCIETY OF JAPAN , The Mathematical Society of Japan

雑誌

Tokyo Sugaku-Butsurigaku Kwai Kiji (ISSN:21852669)

巻号頁・発行日

vol.7, no.3, pp.39-46, 1896 (Released:2010-03-16)