著者
立花 政夫
出版者
一般社団法人日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.47, no.6, pp.355-361, 2007-11-25

Oscillatory synchronized activities are generated among visual neurons in a manner that depends on certain key features of light stimulation. Although these activities are assumed to play an important role in perceptual integration, their functional significance has yet to be elucidated. We performed behavioral tests and multi-electrode recordings from retinas isolated from the frog. Pharmacological manipulation of the oscillatory synchronized activities in a class of retinal ganglion cells (dimming detectors) induced correlated changes in escape behavior. The retinal oscillatory synchronized activities are likely to encode escape-related information in frogs.
著者
中野 修一 杉本 直己
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.46, no.5, pp.251-256, 2006 (Released:2006-09-25)
参考文献数
29
被引用文献数
1

The medium of biomolecules in a living cell differs remarkably from a dilute solution, and many properties of biomolecules that are not observed in vitro are emerged as a result of such intracellular environments. Molecular crowding which is one of the important intracellular environments changes equilibria and rates of biomolecular interactions. Studies with solutions containing high concentration of water-soluble inert cosolutes reveal influences of the molecular crowding on the structures and interactions of proteins and nucleic acids, providing significant insights not only into traditional biology but also bionanotechnology.
著者
林 重彦
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.46, no.2, pp.76-81, 2006 (Released:2006-03-25)
参考文献数
15

Chemical reactions play important roles in biological functions. In order to elucidate molecular mechanism of the chemical reactions in biosystems, so-called hybrid quantum mechanical/molecular mechanical (QM/MM) methods have been developed and applied to many biochemical reactions recently. The methods permit one to calculate electronic states of reaction substrate molecules in protein binding pockets by taking into account molecular interactions with the surrounding protein environment. In this review, we survey our QM/MM studies for chemical reactions in rhodopsin photoreceptor proteins and F1-ATP synthase along with a brief introduction of the methodology.
著者
右田 たい子 吉田 匡
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.44, no.2, pp.81-86, 2004 (Released:2004-03-23)

Plant heme oxygenase (HO), which catalyzes conversion of heme to biliverdin, being further converted to photo-receptive phycobilins, had been known only in the cell extracts of primitive red algae and cyanobacteria for these twenty years. Recent development of gene analysis, however, has shown that HO is ubiquitously contained in variety of living species. We have succeeded for the first time in obtaining recombinant HO protein of cyanobacteria and in characterizing the HO protein and its heme complex by spectroscopic analyses. Here, we review the existence, role, and characteristics of cyanobacterial and plant HOs in comparison with those of mammalian and bacterial HOs.
著者
川端 猛 西川 建
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.40, no.1, pp.52-56, 2000-01-25 (Released:2000-04-12)
参考文献数
7
被引用文献数
1 1 1