著者
井奈波 良一
出版者
The Japanese Society for Hygiene
雑誌
日本衛生学雑誌 (ISSN:00215082)
巻号頁・発行日
vol.38, no.4, pp.748-757, 1983-10-30 (Released:2009-02-17)
参考文献数
25

In an effort to clarify the mechanism underlying stress-induced hyperuricemia, rises in uric acid in the plasma of rats which had been subjected to immobilization stress were investigated. Two types of stress were investigated-fixation in a supine position for 3mins and immobilization in a Ballman cage for 6mins.Immobilization in a supine position caused immediate increases of up to 400% in uric acid levels. This hyperuricemic response could be enhanced slightly by pre-treatment with propranolol, or depressed to approximately 50% that of the control level with phentolamine, or to 60% by adrenal demedullation. In demedullated rats, although hexamethonium markedly inhibited the rise of uric acid, it did not eliminate it entirely. Neither phentolamine nor atropine had any significant effects. Such results indicate that two different mechanisms are involved in the hyperuricemic response-the adrenal epinephrine-dependent reaction mediated via α-receptors, and the epinephrine-independent reaction in which autonomic nerves other than the adrenal medulla might be involved.The uric acid levels in the liver markedly increased in response to stress, however those in other tissues did not change. As with changes in plasma, increases in liver uric acid went only as far as 60% of the levels of the control group after adrenal demedullation. These results support the view that the stress-induced increases of plasma uric acid levels are due to raised production of uric acid occurring only in the liver.Stress did not cause changes in liver adenine nucleotides-ATP, ADP and AMP. Although tissue lactate levels had increased following stress, they did not parallel changes in tissue uric acid, which may exclude the possibility that increased dproduction of liver uric acid is caused by decreases in adenine nucleotides or by non-specific effects, such as tissue hypoxia.Immobilization in a Ballman cage did not raise the levels of uric acid in plasma. However, after treating rats with phentolamine, the amount of plasma uric acid doubled after stress. Propranolol had no such effects. In demedullated rats, stress failed to cause increases in uric acid even after phentolamine-treatment. It can be concluded therefore that the hyperuricemic response is caused by adrenal epinephrine and that in sharp contrast to the stress caused by immobilization in a prone position, the action of epinephrine is mediated via β-receptors.
著者
井奈波 良一
出版者
日本健康医学会
雑誌
日本健康医学会雑誌 (ISSN:13430025)
巻号頁・発行日
vol.27, no.4, pp.294-302, 2019

<p>女性看護師の主観的幸福度に関連する職業性ストレスを明らかにすることを目的に,A総合病院の経験年数1年以上の女性看護師318名(年齢35.6±11.3歳)の自記式アンケート調査結果について分析した。職業性ストレスの把握には,新職業性ストレス簡易調査票の短縮版を使用した。対象者を主観的幸福度が「高い」,「中庸」,「低い」の3群に分け,多重ロジスティック回帰分析を行った。その結果,主観的幸福度が「高い」は,職業性ストレス要因の指標である「仕事の資源」の中の「仕事の適性」(オッズ比1.83),「同僚からのサポート」(オッズ比1.24),「家族や友人からのサポート」(オッズ比1.30)および「キャリア形成」(オッズ比2.54)の各得点が高いことに有意に関連していた(p<0.01またはp<0.05)。また,主観的幸福度が「高い」は,アウトカムでは,「活気」(オッズ比1.24),「家庭満足度」(オッズ比3.03)および「ワーク・エンゲイジメント尺度」(オッズ比1.05)の各得点が高いことに有意に関連し(p<0.01),「抑うつ感」(オッズ比0.87)得点が低いことに有意に関連していた(p<0.01)。以上のことから,経験年数1年以上の女性看護師の主観的幸福度が「高い」ことは,仕事の資源に有意に関連していることがわかった。</p>
著者
井奈波 良一 岩田 弘敏
出版者
一般社団法人 日本温泉気候物理医学会
雑誌
日本温泉気候物理医学会雑誌 (ISSN:00290343)
巻号頁・発行日
vol.53, no.4, pp.189-194, 1990 (Released:2010-04-30)
参考文献数
9

To clarify the relationship between the occurrence of the attacks of Raynaud's phenomenon and weather, maximum, minimum and mean air temperatures in winter were surveyed on the days in which the attacks of Raynaud's phenomenon occurred in 4 female students with Raynaud's phenomenon in the fingers. The results obtained were as follows:1) In general, the percentages of the days when the attacks of Raynaud's phenomenon occurred was the highest from the end of November to December, compared to the January and February results.2) Minimum and mean air temperatures on the days excluding holidays when the attacks of Raynaud's phenomenon occurred were significantly lower than those on the days when the attacks did not occur for the subject who went to school from her own home; this result was not noticeble for the others who lived at the dormitory. In all subjects there were no differences in the maximum air temperatures between the days when the attacks of Raynaud's phenomenon occurred and the days when the attack did not occur.
著者
足立 はるゑ 井上 眞人 井奈波 良一 岩田 弘敏
出版者
公益社団法人日本産業衛生学会
雑誌
産業衛生学雑誌 (ISSN:13410725)
巻号頁・発行日
vol.41, no.4, pp.79-87, 1999-07-20
被引用文献数
9 6

某公立病院看護婦の精神健康状態とストレス対処行動の問題を検討するために230名の看護婦を対象に自記式質問紙調査をおこなった. GHQ 60及びSSCQによる評価ではストレッサー及びストレス評価尺度での高得点者が多くいることがわかった. GHQでは卆後1-2年の看護婦, 婦長, 手術室及び外来勤務の看護婦の精神健康度が低い傾向を示した. SSCQでの高得点者は卆後5年未満と当院で仕事の中心的な存在となっている卆後10年以上の者に多かった. 本調査で特徴的なことはGHQ調査で精神健康度が高い者のなかにもストレス対処行動等において高得点者, つまりストレス予備群を発見できたことである. 以上より, 職場の健康管理において, 職場環境及び労働条件, 勤務配置, 卆後教育等の配慮が必要であると共に看護婦自身が自らの健康状態やストレスを自覚し, 主体的な健康行動をとることが重要であると考えられた.
著者
井奈波 良一 井上 眞人
出版者
岐阜大学
雑誌
基盤研究(C)
巻号頁・発行日
2009

1年目研修医、研修医以外の病院勤務医および病院看護師を対象に職業性ストレス、勤務状況、日常生活習慣、燃え尽き度、仕事満足度、健康支援策等に関するアンケート調査を行い、職業性ストレス、燃え尽き、過度の眠気の要因を分析し、対策を立案・実施した。さらに再度、アンケート調査を行い、対策の効果を評価した。また、病院看護師を対象にフルオーダリングシステム導入前後でアンケート調査を行い、その健康影響を評価した。
著者
村田 公一 井奈波 良一 岩田 弘敏
出版者
日本衛生学会
雑誌
日本衞生學雜誌 (ISSN:00215082)
巻号頁・発行日
vol.52, no.3, pp.562-566, 1997-10-15
参考文献数
5
被引用文献数
1

The researches of masking made it clear that there is a bandpass like a filter in the auditory system. This is called the auditory filter and its central frequency is thought to be the frequency of an acoustic signal. If there exist this kind of filter, the authors expected that the noise image which is perceived when pure tone and noise simultaneously presented is different from the one which is perceived when noise is presented independently. The authors chose an interrupted pure tone as an acoustic signal and continuous white noise as noise, and experimented to investigate the pure tone effect on perception of white noise. As a result, two stimulus tones induced three sound images, which are sound images of continuous noise, a pure tone and pulsed noise. The sound image which listeners did not expect to hear was the pulsed noise image. This phenomenon was thought to be an auditory induction; the inducer is the sound image of the white noise presented with the silent part of pure tone of interrupted pure tone and the inducee is that of the white noise presented with pure tone part of interrupted pure tone. This pulse phenomenon suggests that pure tone change the loudness of white noise. This finding is interesting for researches of auditory mechanism and for the field of hygienics with protecting the auditory system and improving hearing under the noisy environment.
著者
杉浦 春雄 前野 浩子 植屋 悦男 井奈波 良一 岩田 弘敏 西田 弘之
出版者
日本衛生学会
雑誌
日本衛生学雑誌 (ISSN:00215082)
巻号頁・発行日
vol.49, no.5, pp.914-923, 1994-12-15 (Released:2009-03-31)
参考文献数
39
被引用文献数
3 3 1

A study was carried out to examine the effects of ingestion of “BON-NARINE” (BN) on mice immune functions. Mice aged 12 weeks were divided into 4 groups. The first group was given BN at 30mg/kg (BN-30 group), the second group was given BN at 90mg/kg (BN-90 group), the third group was given zymosan at 50mg/kg (Zy group) and the fourth group was a control receiving no treatment. The mice of groups BN-30 and BN-90 were given BN p. o. at doses of 30mg/kg and 90mg/kg per day for 20 consecutive days, respectively. The mice of group Zy were given zymosan i. p. at a dose of 50mg/kg per day for 2 consecutive days.The results obtained were as follows:1) Potentiation of phagocytic function of the reticuloendothelial system, examined by the carbon clearance method, was seen in the BN-30, BN-90 and Zy groups.2) The glucose consumption of peritoneal macrophages (Mφ) increased significantly in the BN-30 and Zy groups, but not in the BN-90 group.3) Superoxide anion (O2-) production of peritoneal Mφ significantly increased in the BN-30 and Zy groups compared with the control group, but an increasing tendency was observed in the BN-90 group.4) The acid phosphatase (APH), β-glucuronidase (GLU) and lactate dehydrogenase (LDH) activities of peritoneal Mφ increased significantly in the BN-30, BN-90 and Zy groups.5) The proliferation of splenocytes induced by Con A in the BN-30, BN-90 and Zy groups significantly increased compared with the control group.These results demonstrated that the ingestion of “BON-NARINE” promotes phagocytic activity in the reticuloendothelial system in mice and has a stimulatory effect on Mφ because of increases in glucose consumption, O2- prodction, APH, GLU and LDH activities in the peritoneal Mφ of mice. BN also intensified the T-cell function represented by Con A-induced splenocyte proliferation.