著者

濃沼 政美 瀬尾 誠 高瀬 知永 西澤 光代 平野 公晟 荒川 秀俊 前田 昌子

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.29, no.2, pp.203-209, 2003-04-10 (Released:2011-03-04)

参考文献数

11

被引用文献数

2 2

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In hospitals oil based ink is occasionally used to write the patient's name, his room number, and names of the drugs that are used in a mixture on the plastic containers used for infusion. This is done to prevent medication errors. In the current study, the effect of an oil-based ink on the infusion fluid was investigated.Using an oil-based ink containing xylene, letters and other characters were written on an infusion fluid container that was made of Polypropylene·Polyethylene·Ethylene vinyl acetate. It was confirmed that some xylene had been transported to the interior of the container (air phase). Furthermore, the xylene concentration in the air phase rose with repetitive writing and erasing, using the same oil-based ink. But no xylene was dissolved in the solution that was in the container (liquid phase).This observation convinced us that it is highly unlikely that the xylene in the ink can be infused directly into a patient's body. However, to assure the quality of the medication that is in liquid form, it is not desirable for a substance that does not normally exist as a component of the medication to move through its container. In the present experiment, physiological saline was used as a solution (liquid phase). Our findings showed that xylene had a high possibility of dissolving in solutions known for high xylene solubility (e. g., solutions with a large amount of amino acids or surfactants). Therefore, it is necessary to design a method to prevent ink from entering a container when an oil-based ink is applied to the outside of it.

著者

菅谷 量俊 川瀬 晴子 西澤 健司 平野 公晟 福生 吉裕

出版者

日本未病システム学会

雑誌

日本未病システム学会雑誌 (ISSN:13475541)

巻号頁・発行日

vol.5, no.1, pp.86-88, 1999-08-31 (Released:2010-09-09)

著者

伊勢 雄也 萩原 研 齋藤 節生 本城 和義 宋 静香 加藤 あゆみ 片山 志郎 西澤 健司 平野 公晟 吉行 俊郎 木山 輝郎 三橋 恭子 亀井 美和子 白神 誠

出版者

公益社団法人日本薬学会

雑誌

藥學雜誌 (ISSN:00316903)

巻号頁・発行日

vol.124, no.11, pp.815-824, 2004-11-01

被引用文献数

1 1

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米国では1983年よりMedicareの入院医療費の支払い方法として,医療費の診断群別定額支払い制度(Diagnosis Related Group/Prospective Payment System;DRG/PPS)が導入されているが,わが国でも平成15年4月より診断群分類(Diagnosis Procedure Combination;DPC)に基づく包括支払い制度が大学病院,国立がんセンター,国立循環器病センターなどの特定機能病院計82施設での入院医療において開始された.その結果,入院患者の在院期間の短縮と入院費用の削減並びに患者満足度の向上などを目的として,クリニカルパス(Clinical Pathway;CP)が日本の医療においてさらに注目されるようになった.日本医科大学付属病院(以下「当院」という)では1998年に「CP研究会」が設立され,患者ケアを医療スタッフがチームとなって行うシステムの構築を検討してきた.1)薬剤部では,その中でも胃癌の切除術患者CPに積極的に携わり,同CPに薬剤管理指導業務を導入することによる有用性並びにその費用対効果についての検討を行い,数多くの知見を得ている.

著者

濃沼 政美 瀬尾 誠 高瀬 知永 西澤 光代 平野 公晟 荒川 秀俊 前田 昌子

出版者

日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.29, no.2, pp.203-209, 2003-04-10

参考文献数

11

被引用文献数

2

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In hospitals oil-based ink is occasionally used to write the patient's name, his room number, and names of the drugs that are used in a mixture on the plastic containers used for infusion. This is done to prevent medication errors. In the current study, the effect of an oil-based ink on the infusion fluid was investigated. Using an oil-bused ink containing xylene, letters and other characters were written on an infusion fluid container that was made of Polypropylene・Polyethylene・Ethylene vinyl acetate. It was confirmed that some xylene had been transported to the interior of the container (air phase). Furthermore, the xylene concentration in the air phase rose with repetitive writing and erasing, using the same oil-based ink. But no xylene was dissolved in the solution that was in the container (Iiquid phase). This observation convinced us that it is highly unlikely that the xylene in the ink can be infused directly into a patient's body. However, to assure the quality of the medication that is in liquid form, it is not desirable for a substance that does not normally exist as a component of the medication to move through its container. In the present experiment, physiological saline was used as a solution (liquid phase). Our findings showed that xylene had a high possibility of dissolving in solutions known for high xylene solubility (e.g., solutions with a large amount of amino acids or surfactants). Therefore, it is necessary to design a method to prevent ink from centering a container when an oil-based ink is applied to the outside of it.

著者

濃沼 政美 西澤 光代 瀬尾 誠 高瀬 知永 平野 公晟 伊藤 克敏 荒川 秀俊 前田 昌子

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.6, pp.541-550, 2002-12-10 (Released:2011-03-04)

参考文献数

5

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The most important aspect of an indwelling inter vascular catheters is to maintain the patency of the catheter. We recently developed a Heparin Lock Flush Solution Kit for use with center vein catheters (only in use at our Hospital). The kit consists of a syringe filled with 9 mL of normal saline (NS) and 1 mL of heparin (1000 IU/mL). We performed the following tests to evaluate the stability, sterility, seal, and dust identification in the preparation. The stability and sterility data indicated that heparin maintained its potency and had no bacterial contamination for 3 months. Testing the seal of the syringe indicated that the seal remained patent at a temperature range of 5°C to 60°C. We also found that even if we sterilized a syringe made of polypropylene using ethylene oxide gas (EOG), no toxins (i.e., ethylene oxide, ethylene chlorohydrin, ethylene glycol) were produced. Next, we examined the preparation time and cost to evaluate the practical benefit of developing the kit. According to our results, the estimated preparation time and cost were 43% and 29% less than for previous methods, respectively. Finally, we put a label on the medicine kit to prevent any misuse by the medical staff.

著者

平田 清貴 松本 宜明 篠崎 聡 清水 万紀子 花田 有里子 原田 尚重 小川 太志 志賀 尚子 野口 裕幸 平野 公晟 山本 保博

出版者

一般社団法人 日本臨床薬理学会

雑誌

臨床薬理 (ISSN:03881601)

巻号頁・発行日

vol.35, no.1, pp.171S, 2004-01-31 (Released:2010-06-28)

参考文献数

1

著者

菅谷 量俊 平野 公晟 福生 吉裕

出版者

日本未病システム学会

雑誌

日本未病システム学会雑誌 (ISSN:13475541)

巻号頁・発行日

vol.7, no.1, pp.111-113, 2001-08-15 (Released:2010-09-09)

参考文献数

2