3 0 0 0 OA IgA腎症に対する扁摘効果と予後予測因子
- 著者
- 赤木 博文 小坂 道也 福島 邦博 土井 彰 笹木 牧 小川 晃弘 西崎 和則 増田 游 松田 充浩 四方 賢一 槇野 博史 清水 順子 杉山 信義
- 出版者
- 日本口腔・咽頭科学会
- 雑誌
- 口腔・咽頭科 (ISSN:09175105)
- 巻号頁・発行日
- vol.9, no.2, pp.253-260, 1997-02-28 (Released:2010-06-28)
- 参考文献数
- 26
- 被引用文献数
- 3
口蓋扁桃摘出術を施行し, 6ヵ月以上経過観察できたIgA腎症47例を対象に, 治療成績と予後予測因子を検討し, 次の結果をえた.1. 扁摘後の最終観察時点での寛解率は, 尿蛋白61.7%, 尿潜血44.7%で, 尿蛋白・尿潜血ともに, 観察期間が長いほど低下傾向にあった.2. 腎病理組織所見の軽症例は, 重症例よりも尿蛋白の寛解率が高かった.3. 扁桃誘発試験陽1生例は, 陰性例よりも尿蛋白の寛解率が低かった.4. IgA腎症の発症年齢, IgA腎症発症から扁摘までの期間, Ccrは, 尿蛋白寛解例と非寛解例の間で有意差を認めなかった.
2 0 0 0 先天性疾患における内耳形態異常
- 著者
- 折田 頼尚 山藤 勇 長谷部 誠司 三浦 誠 西崎 和則
- 雑誌
- Otology Japan (ISSN:09172025)
- 巻号頁・発行日
- vol.13, no.4, 2003-09-12
1 0 0 0 OA 異嗅症のアンケート調査結果から -分類試案と将来展望-
- 著者
- 小川 晃弘 岡野 光博 土井 彰 前田 幸英 西崎 和則 久保田 聡 古川 仭
- 出版者
- Japan Rhinologic Society
- 雑誌
- 日本鼻科学会会誌 (ISSN:09109153)
- 巻号頁・発行日
- vol.42, no.1, pp.23-27, 2003-04-01 (Released:2010-03-11)
- 参考文献数
- 11
- 被引用文献数
- 1 1
Changes in the sense of smell may be quantitative and qualitative, or possibly even a combination. Quantitative changes may manifest themselves partly as hyperosmia and partly as hyposmia, although hyposmia is much more common. Qualitative changes are segignated a parosmia. Disosmia is a condition in which stimulation of the sense of smell does not result in an adequate olfactory impression, but rather in a distorted sensation, usually unpleasant. The precise mechanism and etiology of parosmia remain to be classified.Recent molecular biological advances enable us to a more accurately assess the prognosis for parosmia or suggest more successful treatment. We present an overview of modern classification or definition of parosmia and related clinical issues requiring greater discussion. We collected 94 parosmic patients from 9 dysosmia clinics and discussed them in this reports.Women over 40 years old are most susceptible to parosmia. Upper respiratory viral disease including common cold, head trauma and also zinc deficiency, are conditions that put patients at high risk for parosmia. About 6% of all patients seen at dysosmia clinics have parosmia. We classified parosmia patients by sites, etiology, and severity.Sites are usually the site of responsible for hyposmia or anosmia. Parosmia patients were divided into organic and functional. The organic type was divided into peripheral, central and mixed peripheral and central. The functional type includes the psychological disorder such as illusions of smell, olfactory hallucination, and the uncinates fits. Etiology was classified as sinonasal disease, upper respiratory disease, head injury, other or miscellaneous. Other categories includes zinc-deficient and drug-inducced. We classified severity as slight, moderate, or severe. Twelve factors, including gender, age, and duration, affect the prognosis of parosmia. We summed up the score for these factors and judged severity. For sever parosmic patients, medical treatment such as medication, local treatment, or surgery must be considered. Major tranquiraizer and surgery should be selected for patients with severe or intractable parosmia.
1 0 0 0 OA ビタミンAの催奇形性に及ぼすアルカロイドの効果
- 著者
- 増田 游 上田 節夫 西崎 和則 木口 真樹 岡本 宏司 小倉 義郎 永井 廣 鈴木 一憲
- 出版者
- THE JAPAN OTOLOGICAL SOCIETY
- 雑誌
- Ear Research Japan (ISSN:02889781)
- 巻号頁・発行日
- vol.17, no.1, pp.478-481, 1986 (Released:2011-08-11)
- 参考文献数
- 5
Authors showed the inhibitory effect of Cepharanthin, a kind of Alkaloid, on the teratogenicity of maternal hypervitaminosis A in the rat in the previous report. At the present study, besides, the effect to the internal malformations induced by maternal hypervitaminosis A were investigated using the same materials of the previous study. Twenty-four fetuses from 2 mothers treated with excessive vitamin A and 31 from 3 mothers treated with both of excessive vitamin A and Cepharanthin were stained with Inouye's bone and cartilage staining method and the findings of their middle ear region were observed under the light stereoscopic microscope. Difference of middle ear findings between 2 groups suggested that the inhibitory effect of Cepharanthin to the teratogenic activity of excessive vitamin A acts even on the internal malformations of middle ear region by the membrane stabilizing effect of Cepharanthin.
1 0 0 0 OA 元ハンセン病患者の鼓膜、耳管咽頭口所見
- 著者
- 大島 昭夫 中井 栄一 西崎 和則 結縁 晃治
- 出版者
- 日本耳科学会
- 雑誌
- Otology Japan (ISSN:09172025)
- 巻号頁・発行日
- vol.10, no.5, pp.571-577, 2000-12-25 (Released:2011-06-17)
- 参考文献数
- 21
The tympanic membrane and nasopharyngeal orifice of the Eustachian tube of 40 former leprosy patients were reported.There were 16 cases of secretory otitis media, 20 ears, in 40 patients.13 cases in these 16 cases have deformity of the nasal cavity, especially a large perforation or defect of the nasal septum, and remarkable atrophy of the nasal conchae.They have a large nasal cavity. In 9 cases, the nasopharyngeal orifice of the Eustachian tube might be deformed due to leprosy.The patients of patent tube are observed in 16 cases, also they are aged.They have little deformity of their nasal cavity and the nasopharyngeal orifice of the Eustachian tube, but their mucous membrane and submucous tissue of the nasopharyngeal orifice of the Eustachian tube is remarkably atrophic.