- 著者
- Kiuchi Atsushi Shimegi Satoshi Tanaka Ippei Izumo Nobuo Fukuyama Ryo Nakamuta Hiromichi Koida Masao
- 出版者
- 一般社団法人 日本体育学会
- 雑誌
- International Journal of Sport and Health Science (ISSN:13481509)
- 巻号頁・発行日
- no.4, pp.10-18, 2006
- 被引用文献数
- 3
The purpose of this study was to investigate the effects of different intensities of resistance exercise training on established bone loss in ovariectomized (ovx-ed) rats by densitometry and histomorphometry. Thirty Female Wistar rats were ovx-ed or sham-operated (SHM) at 3 months of age and maintained untreated for 5 months after surgery to establish osteopenia. When they reached 8 months, the ovx-ed rats were divided into four groups in accordance with varying weights applied to a squat-training device: The weight classifications were 1) kept sedentary (OVX); 2) lifted 0 g (LOW); 3) 750 g (MID); and 1500 g (HIGH). The rats in the three training groups performed weight-lifting of 10 reps, performing 2 sets per day, 3 days a week for a ten week period. The Femora and tibiae were removed from each rat and were used for analyses. Ovx induced a significant loss of total BMC in all the bones tested. The ovx-induced femoral BMC loss was observed at all locations tested on the bone (proximal, shaft, and distal), and exercise-intensity dependent restoration was found at the proximal and the distal sites, but not at the shaft. In the tibia, ovx-induced significant bone loss occurred only at the proximal metaphyseal site. The training increased the tibial BMC of all sites in an exercise-intensity dependently, irrespective of the degree of ovx effect. At the tibial shaft, the training increased the cortical bone mass significantly above sham level by the bone apposition at the periosteum. At the proximal tibial metaphysis, exercise had no effect on the cancellous bone volume after ovx-induced bone loss. This finding suggests that the exercise induced bone increase in the ovx-ed rats was from cortical bone, not from cancellous bone, at least in the proximal tibia. These findings indicate that the weight-lifting exercise in rats reversed the ovx-induced bone loss in an exercise-intensity dependent and site-specific manner, even in established osteopenic skeleton 5 mon after ovx.
- 著者
- Shoko FUKUYAMA Minato NAKAZAWA Ryutaro OHTSUKA
- 出版者
- The Japanese Society of Health and Human Ecology
- 雑誌
- 民族衛生 (ISSN:03689395)
- 巻号頁・発行日
- vol.71, no.4, pp.157-167, 2005-07-31 (Released:2010-06-28)
- 参考文献数
- 21
- 著者
- Nakano Takashi Fukuyama Hidetoshi
- 出版者
- 一般社団法人日本物理学会
- 雑誌
- Journal of the Physical Society of Japan (ISSN:00319015)
- 巻号頁・発行日
- vol.50, no.8, pp.2489-2499, 1981-08-15
- 被引用文献数
- 1 111
Our previous calculations of the lattice distortion and the formation energy ofa soliton in the one-dimensional antiferromagnetic Heisenberg spin-Peierlssystems are refined and extended to the case of X Y-Z model. The spin degree offreedom are represented by the phase Hamiltonian with the help of boson repre-sentation of fermions introduced by the Jordan-Wigner transformation. Parame-ters in this phase Hamiltonian are adjusted so that spin wave velocity and exponentof correlation function agree with exact results. This adjustment is shown togive also exact spin susceptibility in the absence of lattice distortion. Based onthis phase Hamiltonian of the X Y-Z model localized excitations (solitons) inthe presence of lattice distortions are examined in details including the width,the formation energy and the magnetic field dependence.
- 著者
- Votinov Mikhail Mima Tatsuya Aso Toshihiko Abe Mitsunari Sawamoto Nobukatsu Shinozaki Jun Fukuyama Hidenao
- 出版者
- Elsevier Ireland Ltd and the Japan Neuroscience Society
- 雑誌
- Neuroscience research (ISSN:01680102)
- 巻号頁・発行日
- vol.68, no.1, pp.59-65, 2010-09
- 被引用文献数
- 16
People always concern about what they have and what they might lose even it is just imaginary property. According to Prospect Theory, the losses might be weighted by subjects higher than gain, which would cause the disparity between the willingness to accept (WTA) and willingness to pay (WTP) compensation in economic valuation. Using functional MRI, we investigated neural correlates of this inconsistent value estimation, known as the endowment effect, during a simple pricing task without economic transaction. Brain activation associated with this price discrepancy was observed in the right inferior frontal gyrus (IFG), where voxel-based morphometry of MRI revealed the positive correlation between gray matter concentration and WTA/WTP ratio. These findings suggest the functional relevance of IFG in WTA/WTP discrepancy for pricing without any actual gain and loss, where an integration of loss aversion-related signals from insula and expected value signals may occur.
1 0 0 0 OA 帝政前期ローマにおける皇帝名の削除と宗教祭司団記録
- 著者
- 福山 佑子 Yuko FUKUYAMA 早稲田大学ヨーロッパ文明史研究所
- 雑誌
- 史觀 = Shikan : the historical review (ISSN:03869350)
- 巻号頁・発行日
- no.172, pp.65-81, 2015-03-25
- 著者
- Atsushi Kiuchi Satoshi Shimegi Ippei Tanaka Nobuo Izumo Ryo Fukuyama Hiromichi Nakamuta Masao Koida
- 出版者
- Japan Society of Physical Education, Health and Sport Sciences
- 雑誌
- International Journal of Sport and Health Science (ISSN:13481509)
- 巻号頁・発行日
- vol.4, pp.10-18, 2006 (Released:2008-01-25)
- 参考文献数
- 26
- 被引用文献数
- 1 3
The purpose of this study was to investigate the effects of different intensities of resistance exercise training on established bone loss in ovariectomized (ovx-ed) rats by densitometry and histomorphometry. Thirty Female Wistar rats were ovx-ed or sham-operated (SHM) at 3 months of age and maintained untreated for 5 months after surgery to establish osteopenia. When they reached 8 months, the ovx-ed rats were divided into four groups in accordance with varying weights applied to a squat-training device: The weight classifications were 1) kept sedentary (OVX); 2) lifted 0 g (LOW); 3) 750 g (MID); and 1500 g (HIGH). The rats in the three training groups performed weight-lifting of 10 reps, performing 2 sets per day, 3 days a week for a ten week period. The Femora and tibiae were removed from each rat and were used for analyses. Ovx induced a significant loss of total BMC in all the bones tested. The ovx-induced femoral BMC loss was observed at all locations tested on the bone (proximal, shaft, and distal), and exercise-intensity dependent restoration was found at the proximal and the distal sites, but not at the shaft. In the tibia, ovx-induced significant bone loss occurred only at the proximal metaphyseal site. The training increased the tibial BMC of all sites in an exercise-intensity dependently, irrespective of the degree of ovx effect. At the tibial shaft, the training increased the cortical bone mass significantly above sham level by the bone apposition at the periosteum. At the proximal tibial metaphysis, exercise had no effect on the cancellous bone volume after ovx-induced bone loss. This finding suggests that the exercise induced bone increase in the ovx-ed rats was from cortical bone, not from cancellous bone, at least in the proximal tibia. These findings indicate that the weight-lifting exercise in rats reversed the ovx-induced bone loss in an exercise-intensity dependent and site-specific manner, even in established osteopenic skeleton 5 mon after ovx.
- 著者
- Atsushi Usami Takuya Sasaki Nobuhiro Satoh Takahiro Akiba Satoshi Yokoshima Tohru Fukuyama Kenzo Yamatsugu Motomu Kanai Masakatsu Shibasaki Norio Matsuki Yuji Ikegaya
- 出版者
- (公社)日本薬理学会
- 雑誌
- Journal of Pharmacological Sciences (ISSN:13478613)
- 巻号頁・発行日
- vol.106, no.4, pp.659-662, 2008 (Released:2008-04-19)
- 参考文献数
- 15
- 被引用文献数
- 24 33
Oseltamivir, a widely used anti-influenza drug, inhibits virus neuraminidase. A mammalian homologue of this enzyme is expressed in the brain, yet the effect of oseltamivir on central neurons is largely unknown. Patch-clamp recordings ex vivo revealed that oseltamivir enhanced spike synchronization between hippocampal CA3 pyramidal cells. Time-lapse multineuron calcium imaging revealed that oseltamivir and its active metabolite evoked synchronized population bursts that recruited virtually all neurons in the network. This unique, so-far-unknown, event was attenuated by muscarinic receptor antagonist. Thus, oseltamivir is a useful tool for investigating a new aspect of neural circuit operation.
- 著者
- Kazuo Kurihara Koji Ishihara Hidetaka Sasaki Yukio Fukuyama Hitomi Saitou Izuru Takayabu Kazuyo Murazaki Yasuo Sato Seiji Yukimoto Akira Noda
- 出版者
- (公社)日本気象学会
- 雑誌
- SOLA (ISSN:13496476)
- 巻号頁・発行日
- vol.1, pp.97-100, 2005 (Released:2005-09-14)
- 参考文献数
- 14
- 被引用文献数
- 36 48
The Meteorological Research Institute (MRI) and the Japan Meteorological Agency (JMA) projected climate change over Japan due to global warming using a high-resolution Regional Climate Model of 20 km mesh size (RCM20) developed in MRI. Projection was made for 2081 to 2100 following a SRES-A2 scenario. Precipitation projected by RCM20 indicated that increased daily precipitation will be seen during the warm season from June to September. Except for this period, the precipitation amount will not change much or will slightly decrease around Japan. The increase during the warm season will be seen only in the western part of Japan. A possible cause of the increase is an El Niño-like SST pattern in the future. Due to the future increased summer SST in the eastern equatorial Pacific, anti-cyclonic circulation to the south of Japan will intensify and will induce a strong water vapor flux along the rim of the anti-cyclonic anomaly. The intensified flux will converge over the western part of Japan and may increase precipitation. Surface air temperature is projected to increase more than 2°C around Japan in January. In summer, the temperature increase will be lower by about 1°C than in winter.
- 著者
- Hajime Fukuyama Tadashi Ishida Hiromasa Tachibana Hiroaki Nakagawa Masahiro Iwasaku Mika Saigusa Hiroshige Yoshioka Machiko Arita Toru Hashimoto
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.50, no.18, pp.1917-1922, 2011 (Released:2011-09-15)
- 参考文献数
- 22
- 被引用文献数
- 3 12
Objective Several scoring systems have been derived to identify patients with severe community-acquired pneumonia (CAP). Recently, España et al (Am J Respir Crit Care Med 174:1249-1256, 2006) developed a clinical prediction rule that predicts hospital mortality, the need for mechanical ventilation, and risk for septic shock. We assessed the performance of this rule and compared it with other published scoring systems. Methods A prospective study was conducted of patients with CAP who were hospitalized at our hospital from April 2007 till May 2009. Clinical and laboratory features at presentation were recorded and used in order to calculate España rule, the pneumonia severity index (PSI), CURB-65, A-DROP, the 2007 Infectious Diseases Society of America/American Thoracic Society (IDSA/ATS) prediction rule and SMART-COP. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were compared for adverse outcomes. We also assessed the association of the España rule criteria and adverse outcomes. Results A total of 505 patients were enrolled in the study. The overall in-hospital mortality rate was 6.5%, and 6.3% of patients were admitted to the intensive care unit (ICU). Sixty-two (12.3%) patients were defined as having severe CAP (in-hospital death or need for mechanical ventilation or septic shock). España rule achieved highest sensitivity and NPV in predicting severe CAP. When ICU admission was the outcome measure, the IDSA/ATS rule and SMART-COP were regarded to be good predictors. Conclusion España rule performed well in identifying patients with severe CAP. As a result, each of the severity scores has advantages and limitations for predicting adverse outcomes.