文献一覧: 0006386X (ISSN) - Ceek.jp Altmetrics

1 0 0 0 2.チロシンアミノ転移酵素の誘導現象と環状ヌクレオチド(ビタミンB研究委員会 : 第242回会議研究発表要旨)

著者: 西塚泰美
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.52, no.3, pp.150-151, 1978

2020-09-03 11:34:16
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1 0 0 0 血小板活性化反応とイノシトール-リン脂質 : 第283回会議研究発表要旨

著者: 西塚泰美
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.59, no.2, pp.76-77, 1985

2020-09-03 11:34:16
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1 0 0 0 OA (3)アスコルビン酸の新機能についての考察 : サイトカイン系との相互作用について(生命システムにおけるビタミンC)

著者: 山本格
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.77, no.7, pp.383-395, 2003-07-25 (Released:2017-12-26)
参考文献数: 44
被引用文献数: 1

In 1989, we have developed a novel vitamin C derivative, 2-O-α-D-glucopyranosyl-L-ascorbic acid (AA-2G), which is highly stable to heat and oxidative stress. This stable form of ascorbate, of which hydroxy moiety at the C-2 position is regiospecifically substituted with glucose, was enzymatically synthesizes with mammalian intestinal and rice seed α-glucosidase, and cyclodextrin glucanotans-ferase from Bachillus stearothermophylus. In 1999, we have also reported a series of 6-acylated forms of AA-2G, 6-Acyl-AA-2Gs, of which hydroxy moiety at the C-6 position of AA-2G is substituted with fatty acids having a different length of carbon chains. Exposure both of AA-2G and 6-Acyl-AA-2G to the mammalian biomembrance results in the formation of active vitamin C by α-glucosidase and/or esterase. AA-2G has been admitted as a medicinal additive for whitening and is widely used in domestic and foreign countries for years. Our of the various acylated derivatives, 6-O-dodecanoyl-2-O-α-D-glucopyranosyl-L-ascorbic acid is considered to be the most expected candidate in application for medicinal use, for examples, preservation solution for the grafts, whitening ingredient, food additives and medicines, because it is the most prominent one in terms of the stability, effectiveness and skin permeability. The two types of ascorbate derivatives are very useful vitamin C source, especially in the tissue culture experiments and contribute the finding of unknown physiological action, and to the clarification of the mode of action of ascorbate. It has been found that vitamin C stimulates the cytokine generation and enhances the cytokine-induced biological activity in immune and neurological responses, although ascorbate alone is without effect. These findings suggest that AA-2G and 6-Acyl-AA-2G not only may serve as useful agents for the medicinal and cosmetic use, but also contributes to shed some light on a new aspect of the biological activity of ascorbate.

2020-08-21 13:44:22
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1 0 0 0 OA 脚気の臨床試験,過去から学ぶこと(<特集>ビタミンB研究委員会平成24年度シンポジウム「B群ビタミンによる疾患の治療」)

著者: 中村重信
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.87, no.11, pp.621-628, 2013-11-25 (Released:2017-08-10)

In 1882-3, many Japanese sailors suffered from beriberi and some died in warships. Japanese government started a committee to prevent beriberi. A parallel controlled trial for beriberi was carried out in 1884 by Kanehiro Takagi who had studied at St Thomas Hospital in London and noticed a remarkable difference in the frequency of beriberi between Japan and London. He determined the ratio of nitrogen to carbon content of food taken by the crew of warship Rhujo which sailed from Japan to Hawaii via Chile and resulted in a miserable occurrence of beriberi. Carbon content in the food was higher during the voyage from Chile to Hawaii than that from Hawaii to Japan, the latter of which brought about beriberi much less frequently. These data prompted Dr. Takagi a trial voyage under similar conditions except partially replacing polished rice with meat in crew's diet. Dr. Takagi postulated the Emperor on importance of diet during the trial voyage. Warship Tsukuba set out on the trial voyage in February, 1884 and arrived at Hawaii without any beriberi patient. The success in preventing beriberi led to taking food without polished rice in Japanese navy, while Japanese army and professors in Tokyo Imperial University neglected these data due to an erroneous assumption that beriberi might be infectious. A mistaken trust in polished rice had prevailed in Japan until 1923 when vitamin B_1 deficiency derived from polished rice was revealed as a cause of beriberi. Thereafter, the incidence of beriberi has decreased dramatically.

2020-08-16 00:31:37
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1 0 0 0 OA 講演5 : 脚気に勝利したビタミン : 高木兼寛が脚気栄養説のために用いた研究方法(『主役はやはりビタミン?!』-知って得するビタミンの新知識-,公益社団法人ビタミン・バイオファクター協会平成23年度「ビタミンの日」記念講演会)

著者: 松田誠
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.86, no.2, pp.128, 2012-02-25 (Released:2017-10-10)

2020-08-16 00:14:17
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1 0 0 0 世界遺産厳島神社と石見銀山(文化講演,日本ビタミン学会第63回大会講演要旨)

著者: 秋山伸隆
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.85, no.4, pp.198-199, 2011

2020-08-05 06:10:23
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1 0 0 0 OA 葉酸代謝関連遺伝子多型と片頭痛 (シンポジウムⅡ「わが国におけるビタミン摂取の現状と課題」)

著者: 古和久典
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.93, no.4, pp.176-177, 2019-04-25 (Released:2020-04-30)

2020-07-29 15:31:55
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1 0 0 0 OA 栄養機能食品と美肌

著者: 梶原伸子
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.77, no.9, pp.549-551, 2003-09-25 (Released:2017-12-26)
参考文献数: 6

2020-07-23 14:57:38
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1 0 0 0 OA 中国製干しカキおよびオイスターソースのビタミンB12含有量の測定と同定

著者: Fei Teng
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.90, no.7, pp.341, 2016 (Released:2017-12-26)

緒言ビタミンB12

2020-07-02 12:24:19
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1 0 0 0 OA 壊血病は過去の病気ではない

著者: 佐藤安訓石神昭人
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.82, no.11, pp.609-611, 2008-11-25 (Released:2017-10-10)
参考文献数: 31
被引用文献数: 2

2020-06-30 22:27:06
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1 0 0 0 OA 第69回大会一般演題要旨(ポスター発表)

出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.91, no.4, pp.293-310, 2017-04-25 (Released:2019-11-25)

2020-05-26 23:33:30
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1 0 0 0 ライナス・ポーリングの「ビタミンCとかぜ, インフルエンザ」, 村田晃訳, 共立出版, B6判, 218ページ

著者: 稲垣長典
出版者: 日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.51, no.8, 1977-08-25

2020-05-02 05:37:39
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https://ci.nii.ac.jp/naid/110002846479

1 0 0 0 OA ビタミンCに与えたポーリングのインパクト(随想のページ)

著者: 村田晃
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.81, no.3, pp.81-82, 2007-03-25 (Released:2017-10-10)

2020-04-29 21:56:37
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1 0 0 0 メンデル無作為化解析を用いた統合失調症と血中ホモシステイン濃度との関連の検討(<特集>ビタミンB研究委員会平成25年度シンポジウム「ビタミンB群が担う脳内アミノ酸代謝と疾患をターゲットにした次世代学術研究-ビタミン研究が切り拓く疾患生命科学のフロンティア」)

著者: 沼田周助
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.88, no.8, pp.413-418, 2014

Previous meta-analyses of studies on the association between blood homocysteine concentration and schizophrenia suggest that elevated blood homocysteine concentration is a risk factor for schizophrenia. However, observational studies on this association have potential problems such as confounding and reverse causation. Mendelian randomization analysis is a method to analyze instrumental variables using genetic variants and can be used for assessing causal relationships. Therefore, we used this Mendelian randomization analysis to investigate the association between blood homocysteine concentration and schizophrenia. As a result, we demonstrated that increased blood homocysteine concentration might be associated with an increased risk of schizophrenia in the Japanese population. This result will offer important insight into the pathophysiology and treatments of schizophrenia.