著者

山崎 隆廣 吉位 尚 黒木 栄司 宮井 大介 林 徹 西村 栄高 吉川 朋宏 吉岡 歩 古土井 春吾 竹野々 巌 市来 浩司 大塚 芳基 中尾 薫 古森 孝英

出版者

一般社団法人 日本歯科薬物療法学会

雑誌

歯科薬物療法 (ISSN:02881012)

巻号頁・発行日

vol.18, no.2, pp.54-58, 1999-08-01 (Released:2010-06-08)

参考文献数

24

被引用文献数

2

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Cases with postoperative infections following teeth extraction are experienced occasionally, however, there have been few reports about the problems following teeth extraction. The purpose of this study was to investigate the influence of general and local background of cases with infections following teeth extraction. The results were as follows:1) The infections following teeth extraction occurred in 11 (2.1%) out of 517 cases.2) There was no relationship between age or underlying disease and the postoperative infection rate.3) The incidence of the infection was the highest after mandibular third molar surgery, however, the relationship between the surgical procedure such as incision or removal of the bone and the infection rate was not found.4) The infection rate of cases with acute inflammation before surgery was higher than that of the cases without any inflammatory signs.5) Prophylactic antibiotic administration was performed on 282 (54.5%) out of 517 cases. The incidence of the infections of the cases with prophylaxis was almost the same as the cases without prophylaxis.6) The postoperative pain in infection cases tends to last longer than the normal course. Therefore, it is important to observe carefully the course of pain to make a diagnosis of postoperative infection.

著者

王 宝禮 今村 泰弘 藤井 健男 音琴 淳一 太田 紀雄 大浦 清

出版者

一般社団法人 日本歯科薬物療法学会

雑誌

歯科薬物療法 (ISSN:02881012)

巻号頁・発行日

vol.23, no.3, pp.101-107, 2004-12-01 (Released:2010-06-08)

参考文献数

29

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本研究では, ヒスタチンを用いて歯肉組織中に最も多く存在するヒト歯肉線維芽細胞に対する影響について検討を行った.ヒスタチンは新鮮ヒト耳下腺唾液を用いてハイドロキシアパタイトクロマトグラフィーによって分離, 精製された.ヒト歯肉線維芽細胞は, インフォームドコンセントのもと抜歯後の歯に付着する歯肉組織から摘出した.ヒト歯肉線維芽細胞は, ヒスタチンを添加し培養された.細胞増殖はMTT分析, DNA合成はBrdU法, Ki-67タンパク質の検出はウエスタンブロット法で行われた.結合分析はオプティカルバイオセンサーによって行われた.ヒスタチンは, ヒト歯肉線維芽細胞に対して増殖率, DNA合成率, Ki-67タンパク質量を増加させた.ヒスタチンとヒト歯肉線維芽細胞の結合が確認できた.以上の結果から, ヒスタチンがヒト歯肉線維芽細胞の増殖を誘導したことを示唆した.将来的に, ヒスタチンが歯周病患者における歯肉線維芽細胞の再生を誘導する可能性があるかもしれない.

著者

影向 範昭 山本 加代子 高橋 美枝子 岡田 道子 遠藤 泰 千葉 智子 遠藤 初恵 鬼頭 健二 鈴木 恵美子 森塚 光子 吉田 紀昭 遠山 邦子 大久保 幸子 大橋 恵 上中 清隆

出版者

一般社団法人 日本歯科薬物療法学会

雑誌

歯科薬物療法 (ISSN:02881012)

巻号頁・発行日

vol.27, no.1, pp.36-44, 2008-04-01 (Released:2010-06-08)

参考文献数

10

被引用文献数

2

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The present study surveyed the application of antimicrobials in dental practice in 17 private dental college or university hospitals in Japan, in order to investigate the actual conditions of using antimicrobials.According to the medicinal virtues, a drug list with percentage was prepared depending upon the number of actual use of internal medicine, injections provided in the prescription or instructions for the 10-day period from September 4 to 15, 2006. Furthermore, a survey of the kind of antimicrobials with consumption for each hospital was also done for the six-month period from April 1, 2006 to September 30, 2006.Classified by medicinal virtues by internal use medicines, the proportion of antibacterial and anti-inflammatory analgesic drugs accounted for 32% each, and gargle and gastrointestinal medicine for 12% and 10% respectively. Among the internal use antimicrobials, usage of the cephem system was 54% whereas penicillin and macrolide system were 23% and 21%, respectively. The largest consumption was cefcapene pivoxil hydrochloride for antibacterial medicines. This drug was widely used in 10 out of 17 hospitals. Erythromycin ethylsuccinate was in second position, followed by cefdinir, rifampicin and ampicillin.The method of marking order of each hospital and order of the total consumption were analyzed and some differences in consumption of different drugs were observed. Many hospitals suggested the use of clarithromycin, cefaclor and amoxicillin although consumption was low.According to the medicinal virtues of injectable medicines, the frequency of use of antimicrobials was the highest (34%) . Among the injectable antimicrobials, the cephem based system (60%) and penicillin system (33%) accounted for more than 90% of the total use. Cefazolin was the most consumed drug, followed by asoxicillin, flomoxef sodium and ceftriaxone.

著者

榎本 鈴代 長畠 駿一郎 鶴田 敬司 貞森 平樹 三宅 実 合田 恵子

出版者

一般社団法人 日本歯科薬物療法学会

雑誌

歯科薬物療法 (ISSN:02881012)

巻号頁・発行日

vol.10, no.1, pp.74-80, 1991-04-01 (Released:2010-06-08)

参考文献数

20

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The effects of eperisone hydrochloride (Myonal®) on 40 patients with temporomandibular arthrosis are evaluated.The results of improvement are as follows : Out of 40 patients, overall improvement was found to be 65 %, pain in improvement was 75.7 %, trismus improvement was 76.2 %, articu-larprocess noises improvement was 27.8 %. Myonal was effective for patients with type I (damage in muscle of mastication), and type II (chronic traumato-disease) was significantly more superior than type III (internal derangements) . The side effects were noted tobe 17.5 %, but there was no specifically serious case, and the cause-and-effect relationship with Myonal was unpredictable.

著者

神谷 洋子 浅田 洸一 栃原 しほみ 山近 重生 石橋 克禮

出版者

一般社団法人 日本歯科薬物療法学会

雑誌

歯科薬物療法 (ISSN:02881012)

巻号頁・発行日

vol.22, no.1, pp.32-35, 2003-04-01 (Released:2010-06-08)

参考文献数

18

被引用文献数

1

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Recently, the use of angiotensin converting enzyme (ACE) inhibitors has increased and so angioedema as a side effect of ACE inhibitor administration is probably increasing. However, angioedema induced by ACE inhibitors has rarely been reported. We reported a case of angioedema (Quincke's edema) of the face that recurred following the administration of a double dose of ACE inhibitor.