著者
松田 健
出版者
日本医科大学医学会
雑誌
Journal of Nippon Medical School (ISSN:13454676)
巻号頁・発行日
vol.69, no.5, pp.508, 2002 (Released:2002-10-25)
参考文献数
2
著者
小澤 一史 松崎 利行
出版者
日本医科大学医学会
雑誌
日本医科大学医学会雑誌 (ISSN:13498975)
巻号頁・発行日
vol.5, no.4, pp.215-220, 2009 (Released:2009-11-17)
参考文献数
9
被引用文献数
1 1

Immunohistochemistry is concerned with the detection of specific biological substances at the light and electron microscopic levels with antibodies labeled with visible markers, such as horseradish peroxidase and colloidal gold. In particular, the immunohistochemistry of electron microscopy has provided much morphological and biological information. Immunoelectron microscopy can be classified into three methods, i.e., pre-embedding, postembedding, and nonembedding methods, on the basis of the step during which the immunoreaction is applied to the biological specimens. Each method has both advantages and disadvantages, so we should select the method according to the biological purpose. An overview of immunoelectron microscopy is given, and several electron micrographs using immunohistochemical techniques are shown.
著者
吉田 寛 真々田 裕宏 谷合 信彦 山下 精彦 田尻 孝
出版者
日本医科大学医学会
雑誌
日本医科大学医学会雑誌 (ISSN:13498975)
巻号頁・発行日
vol.1, no.4, pp.161-167, 2005 (Released:2005-11-09)
参考文献数
67

Bleeding from esophagogastric varices is a catastrophic complication of chronic liver disease. We have been attempted surgery, embolization, and endoscopic treatment for the treatment of esophagogastric varices. Endoscopic injection sclerotherapy (EIS) is an established treatment for esophageal varices. EIS is associated with a high incidence of local and systemic complications. Endoscopic variceal ligation (EVL) is increasingly used because of its safety and simplicity and because no sclerosant is used. Nevertheless, EVL is not always effective, and early recurrences have been reported. Furthermore, most patients with esophageal varices treated endoscopically require treatment for recurrent varices. We invented that EVL performed three times at bimonthly intervals. EVL performed at bimonthly intervals for the treatment of esophageal varices attained a higher complete eradication rate, a lower recurrence rate, and a lower additional treatment rate. It is generally believed that bleeding from gastric varices is more severe than bleeding from esophageal varices, but bleeding from gastric varices occurs less commonly than from esophageal varices. The endoscopic risk factors for bleeding from esophageal varices include presence of raised red markings, cherry-red spots, blue color, and large size. However the risk factors for bleeding from gastric varices have yet to be characterized. Once gastric variceal hemorrhage did occur, bleeding from these varices was successfully stopped in all cases. Therefore, prophylactic treatment of gastric varices is not recommended.
著者
石川 信克
出版者
日本医科大学医学会
雑誌
Journal of Nippon Medical School (ISSN:13454676)
巻号頁・発行日
vol.67, no.5, pp.367-370, 2000 (Released:2001-11-15)
参考文献数
10
被引用文献数
2 2
著者
福永 慶隆
出版者
日本医科大学医学会
雑誌
Journal of Nippon Medical School (ISSN:13454676)
巻号頁・発行日
vol.67, no.2, pp.83-91, 2000 (Released:2001-09-25)
参考文献数
34
被引用文献数
1