著者

高市 真一

出版者

日本医科大学医学会

雑誌

日本医科大学医学会雑誌 (ISSN:13498975)

巻号頁・発行日

vol.8, no.4, pp.264-267, 2012 (Released:2012-12-28)

参考文献数

21

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Phototrophic organisms including land plants, algae, and photosynthetic bacteria can synthesize carotenoids for photosynthesis. A part of bacteria and fungi also synthesize carotenoids. On the other hand, animals cannot synthesize carotenoids, and they ingest carotenoids from foods. Most animals can modify the carotenoids, such as oxidation and reduction. Humans contain usually six kinds of carotenoids: β-carotene, α-carotene, lycopene, β-cryptoxanthin, zeaxanthin, and lutein. Furthermore in this paper, functions of carotenoids in animals especially humans are briefly summarized: Carotenoids are essential for organisms living under oxygen to prevent active oxygen. β-Carotene is cleaved into retinal by β-carotene-15,15'-monooxygenase. Retinal is used as photoreceptor in eye. Lutein and zeaxanthin are accumulated in macula of eye for prevent blue light. From epidemiology, carotenoids in vegetables have anticancer activities. Lycopene might prevent prostatic cancer. Some carotenoids have also functions, such as antioxidant, anticancer, and anti-obesity.

著者

広瀬 貞雄

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.37, no.1, pp.1-17, 1970-02-15 (Released:2010-10-14)

参考文献数

89

著者

進藤 久夫

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.62, no.5, pp.439-446, 1995-10-15 (Released:2010-03-01)

参考文献数

18

被引用文献数

11 11

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The lumbar multifidus muscle was dissected with particular reference to its innervation in 10 Japanese adults and 10 fetuses from 5 to 10 months old. The results were as follows:1) The multifidus muscle attached to the spinous process of a lumbar vertebra was segmentally innervated by the medial branch of the dorsal ramus of the lumbar nerve on a level with the spinous process.2) The motor point of the nerve innervating the multifidus muscle in adults was slightly ventro-caudal to that portion of the lumbar spinous process with muscle attached.3) The multifidus muscle in fetuses was thinner and flatter than that in adults. The motor point of the nerve innervating this muscle was slightly caudal at the lateral margin of the muscle to that portion of the lumbar spinous process with the muscle attached. These differences can be attributed to the fact that muscles used to oppose gravity are undeveloped in fetuses.4) There was variation in 5 fascicles in total, in which the medial branch of the dorsal ramus of a lumbar nerve entered the multifidus muscle originating at the spinous process of a lower lumbar vertebra.

著者

柏原 正和

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.22, no.12, pp.1113-1114, 1955

著者

品川 嘉也

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.54, no.3, pp.333-338, 1987-06-15 (Released:2009-07-10)

参考文献数

10

著者

中村 博子 伊勢 雄也 片山 志郎

出版者

日本医科大学医学会

雑誌

日本医科大学医学会雑誌 (ISSN:13498975)

巻号頁・発行日

vol.8, no.3, pp.195-198, 2012 (Released:2012-08-31)

参考文献数

15

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Patients with cancer-related anorexia (CRA) have a lack of appetite, early satiety, taste changes, poor performance status, and diminished quality of life. Megestrol acetate is a standard treatment for CRA. Recently, olanzapine has been reported to be effective for treating refractory nausea and vomiting induced by chemotherapy in patients with cancer. A clinical trial has found that the combination of megestrol acetate and olanzapine is effective for patients with CRA. In this article we describe the treatment of CRA using olanzapine.

著者

大内 望 品川 寿弥 村田 知昭 明樂 重夫 竹下 俊行

出版者

日本医科大学医学会

雑誌

日本医科大学医学会雑誌 (ISSN:13498975)

巻号頁・発行日

vol.3, no.3, pp.147-150, 2007 (Released:2007-07-12)

参考文献数

15

被引用文献数

1 1

---

We present a case of pregnancy complicated by sacroiliitis. The patient complained of lumbar pain, dysbasia, and fever of 37.8°C at 14 weeks' gestation. Sacroiliitis was diagnosed on the basis of magnetic resonance imaging. Treatment included bed rest, antibiotics, and analgesic medications. Complete recovery required 2 months.

著者

村田 朗

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.63, no.5, pp.404-408, 1996-10-15 (Released:2010-03-01)

参考文献数

4

著者

山寺 博史 中村 秀一 鈴木 英朗 遠藤 俊吉

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.64, no.1, pp.53-56, 1997

被引用文献数

1

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We experienced a 49 years old female SAD patient who showed a good response the next day after alprazolam 1.2 mg administration. The back ground EEG of the patient showed a abnormal EEG with slow waves. The personality was colored with histerical features. The nadir of body core temperature from rectum slightly delayed in remission phase compared with depressive phase. The patient became hypomania and calmed down gradually. Alprazolam tratment is seemed to be available for SAD patients. (J Nippon Med Sch 1997; 64: 53-56)

著者

森本 正昭

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.23, no.9, pp.761-762, 1956

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The number of the rhythmical heart beats of the 29 abortives from 6 to 21 mm long early human embryos were in a first minute after birth 40-49 by 9 (31.3%), 20-29 by 6 (20.6%), the mean of all 29 embryos 41.5 per minute.

著者

及川 眞一

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:13454676)

巻号頁・発行日

vol.68, no.2, pp.194-197, 2001

被引用文献数

1

著者

池田 良吉

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.19, no.2, pp.271-283, 1952-02-15 (Released:2010-10-14)

参考文献数

10

著者

洲鎌 盛吉

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.27, no.1, pp.172-173, 1960

著者

伊藤 保彦

出版者

日本医科大学医学会

雑誌

日本医科大学医学会雑誌 (ISSN:13498975)

巻号頁・発行日

vol.6, no.1, pp.40, 2010 (Released:2010-03-05)

著者

守屋 高恒

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.26, no.2, pp.186-188, 1959-02-15 (Released:2010-10-14)

著者

街 智

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.27, no.6, pp.1193-1195, 1960-06-15 (Released:2010-10-14)

参考文献数

3

著者

元文 芳和 伊藤 博元

出版者

日本医科大学医学会

雑誌

日本医科大学医学会雑誌 (ISSN:13498975)

巻号頁・発行日

vol.2, no.1, pp.42-46, 2006 (Released:2006-03-10)

参考文献数

8

被引用文献数

1 1

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Many patients require a medical check-up as an outpatient with the chief complaint of low back pain, because the morbidity of low back pain is high. Many cases of acute lumbago resolve spontaneously, but some cases shift to chronic lumbago. Low back pain is classified as somatic pain and radicular pain resulting from the lumbar area, and other pain originating in the abdomen and pelvic viscera. We describe it mainly as low back pain and inter vertebral disc herniation. At the time of diagnosing inter vertebral disc herniation, the straight leg raising test is a very useful physical examination and MRI is the best examination for imaging studies. The therapeutic principle is conservative treatment, because symptoms of inter vertebral disc herniation may improve naturally. Surgical treatment is chosen when severe nerve damage, such as bladder problems or dropfoot, is present and patients are in significant pain.

著者

清行 緒方

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.54, no.1, pp.17-26, 1987-02-15 (Released:2009-12-04)

参考文献数

30

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A new unstable hemoglobin variant, Hb Sendagi (β42Phe→Val), was found in a Japanese male and his daughter both suffering from moderate hemolytic anemia. The structure of the variant was determined and the functional properties were studied. The results obtained are as follows.1) The variant was electrophoretically silent, but the abnormal β-chain was found to emerge ahead of the normal, 6-chain when the hemolysates from the patients were applied to a reverse-phase HPLC.2) The tryptic peptides were prepared with the variant β-chain enriched by isopropanol precipitation and column chromatography on CM-cellulose. The abnormal peptide, βTx-5, was separated by fingerprint mapping or by reverse-phase HPLC of the tryptic peptides.3) Sequence analyses of the abnormal peptide revealed that the phenylalanine in position 42 (CD1) of the β-chain was replaced by valine. The variant was named as Hb Sendagi according to the place where it was discovered.4) Hb Sendagi showed a decreased stability upon heat denaturation and isopropanol precipitation tests, and was oxidized faster than Hb A by atmospheric oxygen in the presence and absence of sodium benzoate.5) The oxygen equilibrium curves of the hemolysates from the propositus also indicated that Hb Sendagi had a lowered oxygen affinity and a normal response to 2, 3-diphosphoglycerate.

著者

大中道 淳

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.38, no.3, pp.131-137, 1971 (Released:2010-10-14)

参考文献数

20

著者

松浦 究

出版者

日本医科大学医学会

雑誌

日本医科大学雑誌 (ISSN:00480444)

巻号頁・発行日

vol.47, no.4, pp.429-437, 1980-08-15 (Released:2010-10-14)

参考文献数

27

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The inferelatia of the fecal E. coli in the mother and child attracts much attention of the investigators and the importance of this interaction has been documented in the literature.However, investigated cases are rather limited and the detailed patho-physiological significance should await further elucidation in future. In this viewpoint the author has isolated the E. coli from the fecal materials of mother and newborn infant chronologically and subtyped serologically. Moreover, concerning infection with reference to the mother-child relationship, circumstantial factors and infulence of the E. coli on mother and child have been investigated in this study.The study also has attempted to elucidate the mechanism how the E. coli settle in human intestine as normal flora.(1) The E. coli in newborn infant was isolated within 24 hours as the rate of 9.2%, 40.8% within 48 hours, and 61.8% within 72 hours.(2) Related to the relationship between delivery time and detection rate of E. coli in newborn intestine, it is very interesting to note that majority of the cases of prolonged delivery time beyond 18 hours disclosed detection of the E. coli within 48 hours.Contrary, in cases which showed delivery time within 18 hours, only detection rate of 35.8% was noted.(3) No significant correlation was observed in detection rate of E. coli and time interval of rupture of membrane and delivery of the babies.(4) Of 561 strains of E. coli separated from mothers and children, 194 strains (34.1%) could be identified serologically.(5) Serological typing disclosed 14 subtypes, namely, 0-1, 2, 18, 6, 13, 4, 8, 14, 15, 25, 12, 21, 23 and 36.(6) Out of 54 cases, 8 cases disclosed identical subtyped E. coli between the mother and child.(7) Among newborns admitted at about the same time, 24 cases (44.4%) of 54 showedidenticalserum types.Based on these observations, it is concluded that the highly probable presence of horizontal dissemination of the E. coli in newborn infants in virtue of circumstantial factors, although vertical dissemination in a mode of the mother to child relation should be present to a lesser extent.