著者
HIDEAKI KANZAWA-KIRIYAMA TIMOTHY A. JINAM YOSUKE KAWAI TAKEHIRO SATO KAZUYOSHI HOSOMICHI ATSUSHI TAJIMA NOBORU ADACHI HIROFUMI MATSUMURA KIRILL KRYUKOV NARUYA SAITOU KEN-ICHI SHINODA
出版者
日本人類学会
雑誌
Anthropological Science (ISSN:09187960)
巻号頁・発行日
pp.190415, (Released:2019-05-29)
被引用文献数
3 29

The Funadomari Jomon people were hunter-gatherers living on Rebun Island, Hokkaido, Japan c. 3500–3800 years ago. In this study, we determined the high-depth and low-depth nuclear genome sequences from a Funadomari Jomon female (F23) and male (F5), respectively. We genotyped the nuclear DNA of F23 and determined the human leukocyte antigen (HLA) class-I genotypes and the phenotypic traits. Moreover, a pathogenic mutation in the CPT1A gene was identified in both F23 and F5. The mutation provides metabolic advantages for consumption of a high-fat diet, and its allele frequency is more than 70% in Arctic populations, but is absent elsewhere. This variant may be related to the lifestyle of the Funadomari Jomon people, who fished and hunted land and marine animals. We observed high homozygosity by descent (HBD) in F23, but HBD tracts longer than 10 cM were very limited, suggesting that the population size of Northern Jomon populations were small. Our analysis suggested that population size of the Jomon people started to decrease c. 50000 years ago. The phylogenetic relationship among F23, modern/ancient Eurasians, and Native Americans showed a deep divergence of F23 in East Eurasia, probably before the split of the ancestor of Native Americans from East Eurasians, but after the split of 40000-year-old Tianyuan, indicating that the Northern Jomon people were genetically isolated from continental East Eurasians for a long period. Intriguingly, we found that modern Japanese as well as Ulchi, Korean, aboriginal Taiwanese, and Philippine populations were genetically closer to F23 than to Han Chinese. Moreover, the Y chromosome of F5 belonged to haplogroup D1b2b, which is rare in modern Japanese populations. These findings provided insights into the history and reconstructions of the ancient human population structures in East Eurasia, and the F23 genome data can be considered as the Jomon Reference Genome for future studies.

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@nobutake_Ishii Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan https://t.co/flimGHLNks the Y chromosome of F5 belonged to haplogroup D1b2b, which is rare in modern Japanese populations. この論文の結論は アイヌが縄文人の祖先をより多く保持しています https://t.co/pfhTaTm1f5
Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan ヤポネシア人のSNP https://t.co/Y1TDl72qns
@WGwaihir @rosswise 元の論文です。 https://t.co/90EKqsPPve
@oyaziMK2 今確認しました。去年神澤さんが出してたやつですね。ちょっと読んでみます。 https://t.co/auRAu4GKii
@xiongmao53 @Isepo2 元論文、かなり込み入った論文なので、読むのに時間がかかりそうなので、一応、リンクを張っておきます。 https://t.co/nei75zAlm3
@m_9_fuji その記事に元の論文へのリンクありますよ。 https://t.co/GGsvrwsmdq 科博のプレスリリースも参考までに。 遺伝子から続々解明される縄文人の起源~高精度縄文人ゲノム~ Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan https://t.co/Mqm2qvBQAV
@Ex_kitaguni @OblakoObLaDa @daykazu @C6HgjZhn8RRamo3 @oku3ma3 @MitsuruSwiftie @unkokusaimevius @sarpa50658381 @ozawajun @safefield @mikki_3octave @Mikaduki_1640 @yamamototakpc @onoderamasaru 篠田謙一『新版日本人になった祖先たち』(NHK出版 2019年)にも同内容が紹介されています。論座の元記事は日本人類学会の英文誌Anthropological Scienceです。 《推定》は私の間違い。元記事では《解読》とあります。 https://t.co/90EKqsPPve
J-STAGE Articles - Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan https://t.co/bO2IYGZf6o
@razibkhan Something that might be of interest to you: https://t.co/EpUtBPTbeo
フナドマリジョウモンピープルですか…。 Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan https://t.co/64wqXW2oWj
@floweroflife396 今回の研究の基本的なことが公開されています。  ↓ https://t.co/f4cgkJonZd
@XENO1311 縄文人の全ゲノムを解析した結果、韓国や台湾の先住民、フィリピン人に近いことがわかりました。研究チームは東ユーラシア集団の中で最も古い時期に分岐した集団とみています。 ↓ の論文より https://t.co/f4cgkJonZd
@GiveMeRumRaisin https://t.co/q1Tbkn0QLm Here's a neat genetics study on Jomon that came out a few days ago.
北海道礼文島の船泊遺跡出土縄文時代人のゲノムを解析した論文が発表されました。 https://t.co/Fr9c5XeQLD
J-STAGE Articles - Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan https://t.co/OE9Jqs3Ur9
プレスリリースだけ先に出ていた縄文人の高精度ゲノム解読論文がオンライン公開になってた。 Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan https://t.co/esss5BhygV プレスリリース→ https://t.co/Uf3zoZx8vS
High-depth nuclear genome sequences from Hokkaido Jomon hunter-gatherers Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan https://t.co/kfiTTSREpO

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