著者
中田 翔治 高嶋 隆太 長野 浩司 木村 浩 班目 春樹
出版者
Atomic Energy Society of Japan
雑誌
日本原子力学会和文論文誌 = Transactions of the Atomic Energy Society of Japan (ISSN:13472879)
巻号頁・発行日
vol.9, no.3, pp.252-270, 2010-09-01
被引用文献数
3

Replacement of nuclear power plants has the possibility of affecting the management of electric power suppliers. Therefore, in the nuclear policy, a depreciation method as an equalization method, which means that part of the investment cost is accumulated as an allowance, and after the start of operation, the depreciation cost in the replacement project is equalized, has been introduced in Japan. In this paper, we evaluate the replacement of nuclear power plants by taking into account the uncertainty of operating costs and the depreciation cost in order to examine the effect of the depreciation method on the decision criteria of the replacement. We found that the equalization method is effective for inducing the acceleration of the replacement. Furthermore, we show the relationship between the uncertainty and the depreciation method. It turns out that as uncertainty increases, the difference in investment threshold between the equalization method and the existing depreciation method decreases, and that in option value increases.<br>
著者
中田 翔 石田 茜 佐藤 駿 田中 優貴 鈴木 聡 Pradeep Abeygunawardhana 西山 成 和田 健司 石丸 伊知郎
出版者
公益社団法人 精密工学会
雑誌
精密工学会学術講演会講演論文集
巻号頁・発行日
vol.2014, pp.65-66, 2014

我々は,無限遠補正結像光学系の光学的フーリエ変換面に,直方体と傾斜プリズムによる透過型位相シフターを挿入した,波面分割型空間的位相シフト干渉法を提案している.これは,スマートフォンなどの結像光学系に,薄い傾斜ガラス板を挿入するだけで,ワンショット(1画像)で1ライン上のフーリエ分光イメージングが可能になる.近赤外領域の分光断層イメージングにより,皮膚などの生体膜表面や内部の成分計測を目指している.
著者
櫻井 一正 中田 翔貴 豊増 明博 橘 秀樹
出版者
近畿大学先端技術総合研究所
雑誌
近畿大学先端技術総合研究所紀要 = Memoirs of Institute of Advanced Technology, Kinki University (ISSN:13468693)
巻号頁・発行日
no.20, pp.31-41, 2015-03

[Abstract] Oligomeric state of the actin interacting protein 2/D-lactate dehydrogenase protein 2( Aip2p/Dld2p)isolated from Saccharomyces cerevisiae was shown to be able to unfold the conformation of pathogenic highly aggregated polypeptides, and has been supposed to be a novel chaperone protein. However, the mechanism of the unfolding activity is little understood. Since experiments for the structure–function relationships of a protein require an efficient expression system, we attempted to use the methylotrophic yeast Pichia pastoris because of its ability of very high expression yield. Changing the vector/protein construct combinations, we examined the secretion expression system of P. pastoris with several Aip2p/Dld2p constructs as well as the intracellular expression system. We did not observe significant expression yields in any construct combinations. RT-PCR analyses revealed that mRNA coding Aip2p/Dld2p was successfully synthesized, suggesting that the structure of Aip2p/Dld2p is inherently unstable and susceptible to proteolysis of the cellular quality control system. [抄録]出芽酵母Saccharomyces cerevisiae から単離されたオリゴメリック蛋白質Aip2p/Dld2p は病原性の蛋白質異常凝集体を解きほぐす活性を持ち, 新規のシャペロン蛋白質であることが示唆されている. しかしながら, その解きほぐし活性の物理化学的メカニズムについてはほとんど調べられていない. 蛋白質の物理化学的解析や構造解析には数十ミリグラム程度の試料が必要であり, そのためには高効率の蛋白質発現系を要する. そこで今回, 我々は他の蛋白質で高収量が報告されているメタノール資化酵母Pichia pastorisによる大量発現を試みた. 種々のAip2p/Dld2p コンストラクト(全長体、N 末端欠損体, システイン→アラニン置換体)とベクター(細胞内発現系、分泌発現系)の組み合わせを試したところ, Aip2p/Dld2p をコードするmRNA の合成は見られたが, 蛋白質の発現は細胞内発現系でも分泌発現系でも見られず, さらに分泌発現系の場合の細胞内にも見られなかった. Aip2p/Dld2p の天然構造は非常に不安定で, ヘテロロガスな発現の場合, 翻訳直後に細胞内の品質管理機構によって加水分解を受けているのではないかと考えられる.近畿大学先端技術総合研究所紀要編集委員会
著者
中田 翔治 高嶋 隆太 長野 浩司 木村 浩 班目 春樹
出版者
一般社団法人 日本原子力学会
雑誌
日本原子力学会和文論文誌 (ISSN:13472879)
巻号頁・発行日
vol.9, no.3, pp.252-270, 2010 (Released:2012-02-08)
参考文献数
16
被引用文献数
1 3

Replacement of nuclear power plants has the possibility of affecting the management of electric power suppliers. Therefore, in the nuclear policy, a depreciation method as an equalization method, which means that part of the investment cost is accumulated as an allowance, and after the start of operation, the depreciation cost in the replacement project is equalized, has been introduced in Japan. In this paper, we evaluate the replacement of nuclear power plants by taking into account the uncertainty of operating costs and the depreciation cost in order to examine the effect of the depreciation method on the decision criteria of the replacement. We found that the equalization method is effective for inducing the acceleration of the replacement. Furthermore, we show the relationship between the uncertainty and the depreciation method. It turns out that as uncertainty increases, the difference in investment threshold between the equalization method and the existing depreciation method decreases, and that in option value increases.