著者

倉持 有香 武田 浩樹 小松 敏彰 尾鳥 勝也 厚田 幸一郎

出版者

日本病院薬剤師会

雑誌

日本病院薬剤師会雑誌 = Journal of Japanese Society of Hospital Pharmacists (ISSN:13418815)

巻号頁・発行日

vol.52, no.10, pp.1298-1300, 2016-10

著者

藤井 仁美 森 貴幸 古川 綾 井上 岳 厚田 幸一郎

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.136, no.2, pp.259-263, 2016 (Released:2016-02-01)

参考文献数

5

---

For prevention of the aggravation of diabetic nephropathy, a treatment method that combines self-care with medical guidance is becoming increasingly important, leading to the development of programs for lifestyle modification for the patients. To assess the effectiveness of such programs, we have conducted a feasibility study of a patient self-care support program with medical collaboration by registered pharmacists in community pharmacies involving patients with diabetic nephropathy who are under treatment at medical institutions, including our hospital. This study evaluated the two primary measurements, which are A) the actual execution rate versus planned programs, and B) the patient satisfaction rate. In addition, the achievement rate of behavioral objectives, satisfaction rate of diabetes treatment, degree of concerns (Diabetes Treatment Satisfaction Questionnaire; DTSQ, Problem Areas in Diabetes; PAID) and other physiological indicators have been evaluated. With the approval of the IRB at Kitasato University, sixteen out of 18 patients have continued to participate in the support program, and the study has shown high patient satisfaction with pharmacist coaching support. Patients have gained interest in managing their lifestyles, thereby increasing self-efficacy. Also, information shared between the pharmacists and the physicians has clarified patients' issues and concerns pertaining to their lifestyles, which were effectively utilized in the coaching program. Through meetings with pharmacists, patients have been reassured of the expertise of the pharmacist and thus gained mutual trust, which leads to the patient's behavioral change. We believe that the collaboration of patients, pharmacists and physicians has resulted in effective team-based patient care.

著者

薄井 健介 小室 治孝 月村 泰規 渡辺 雄一 神 雅人 伊藤 千裕 井口 智恵 野島 浩幸 井上 岳 厚田 幸一郎

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.39, no.6, pp.338-346, 2013-06-10 (Released:2014-06-10)

参考文献数

13

被引用文献数

3

---

We investigated the effectiveness of using a “Sports Pharmacist” to prevent the occurrence of doping in sports.During the first step, we individually interviewed 17 high school softball team athletes and determined their regular and/or occasional use of prescription and OTC medications, herbal agents, vitamins and supplements. A total of 76% of these players were either taking or had access to medications for occasional use that contained prohibited substances. Athletes determined to be using a prohibited compound were sent a written notice that recommended they avoid carelessly taking these banned substances.In the subsequent step, we gave an educational lecture to the entire team on how to avoid doping in sports. Before and after the presentation, we evaluated the effectiveness of the lecture by examining the athletes’ knowledge and awareness of anti-doping in sports. The results indicated a significant difference after the lecture with regard to appropriate knowledge and awareness of anti-doping in sports. This specific awareness continued for at least a month.In summary, medication reviews and one-on-one consultation with athletes in conjunction with a follow-up educational lecture to the team as a group resulted in successfully educating and helping team members avoid doping. In addition, these findings demonstrated the effectiveness of the “Sports Pharmacist” profession in working with athletes to help prevent doping in the future.

著者

古川 綾 浅田 美子 森 貴幸 井上 岳 厚田 幸一郎

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.136, no.2, pp.251-258, 2016 (Released:2016-02-01)

参考文献数

12

---

The Asheville Project® began in 1996 in Asheville, North Carolina, where community pharmacists, in collaboration with physicians, provide health coaching to patients with lifestyle diseases to accomplish their improved self-management of the disease. The project has now widely expanded across the United States. With periodical coaching by pharmacists, according to the reports of these programs, patients have been reported to show improvements in self-management and laboratory data, including the number of doctor visits, medication adherence and the number of foot examinations. Economically, the total medical costs for this disease have decreased 34% over a 5-year period by complying with the Asheville Project. In implementing this model in Japan, various questions, such as the feasibility for busy pharmacists to expend 30-60 min for meeting individually with patients, effective collaboration between pharmacy and physician, patients' acceptance of support by pharmacists to modify their behavior, etc. had to be answered. Thus, we developed a program entitled, “A Health Coaching Program by Community Pharmacists in a Collaborative Practice,” aimed at preventing the aggravation of lifestyle diseases; we evaluated its feasibility for the above mentioned concerns. The content of this coaching program has been prepared with reference to the Asheville Project® and with the support of Kitasato University School of Pharmacy and the Iowa Pharmacy Association, USA. We herein introduce this coaching program, as well as what the pharmacists have learned through this program.

著者

阿部 真也 松本 忍 小林 彦登 斎藤 太寿 宮下 博幸 高野 照子 堺 直子 柴田 壮一 厚田 幸一郎

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.14, no.2, pp.75-81, 2012 (Released:2012-09-04)

参考文献数

10

被引用文献数

2

---

Objective: In the intensive care unit (ICU), drugs are administered in sequence as the conditions of the patient change rapidly, and there are often cases where many injections are administered simultaneously.  For this reason, it is important to quickly select the appropriate administration route.  In this study, we prepared a quick reference table for incompatibilities of frequently used and highly important injections in the ICU (referred to as the “quick reference table”) that will enable selection of the appropriate administration route, and we investigated the status of use and usefulness of this quick reference table.Methods: The drugs included in the quick reference table were extracted from prescription records from May to October 2009, and these were finalized by discussions with the nurses in the ICU.  Three reference materials were used: Manual on the Supervision of Injection Preparation (3rd Edition), Data Search on Injection Incompatibilities 2009, and MICROMEDEX®.  The survey was conducted with all 12 nurses in the ICU after 4 months of distributing the quick reference table.Results: The quick reference table included 57 pharmaceutical items, and compatibility was classified into 10 categories.  The quick reference table was prepared as one A3 page for convenience.  The retrieval rate of the survey was 100%.  The average number of years of practical experience as a nurse was 12.2 years, and 11 out of 12 nurses used the quick reference table.  Of the 11 nurses who used the table, 6 answered that it was “very useful,” while 4 answered that it was “useful.”  All 11 nurses who used the quick reference table answered that they “consulted the pharmacists less frequently.”Conclusion: Satisfactory evaluations were obtained with regard to the details included in the quick reference table, and the table was estimated to be highly useful and important even for ICU nurses with many years of experience.  Furthermore, it was suggested that the quick reference table was also useful in reducing the workloads of the pharmacists.

著者

柴田 壮一 伊藤 千裕 小室 治孝 増渕 幸二 宮下 博幸 薄井 健介 貝沼 潤 厚田 幸一郎

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.11, no.3, pp.173-179, 2010-02-28 (Released:2010-08-10)

参考文献数

7

被引用文献数

2

---

Objective: In the Drug Informatics in Department of Pharmacy, Kitasato Institute Hospital (hereinafter “the hospital”), we have had question-and-answer sessions regarding doping agents (banned drugs) among doctors and other workers and prepared an Anti-doping Quick Reference List (hereinafter “the list”), facing an urgent need to provide precise information quickly.Methods: The list consists of drugs adopted by the hospital and over-the-counter drugs according to package inserts, interview forms, and other sources of information.Results: In the list, hospital and over-the-counter drugs are classified into three categories in terms of a doping test: (1) “Non-banned” (drugs that can be used), (2) “Banned” (drugs that cannot be used), and (3) “Suspected” (unclear drugs) with their half lives for elimination as an indicator of the disappearance time from the body and divided by medicinal effect.  In addition, we indicated any drug for which the Therapeutic Use Exemption (TUE) application (hereinafter, TUE application) is required before use.Conclusion: The list prepared in this investigation offers many benefits, including precise and quickly available information on banned and non-banned drugs, ease in suggesting alternatives, and avoidance of failure in TUE application.

著者

厚田 幸一郎 沼里 友紀 本橋 茂 村瀬 勢津子 吉山 友二 小林 輝明 朝長 文弥

出版者

Society of Oto-rhino-laryngology Tokyo

雑誌

耳鼻咽喉科展望 (ISSN:03869687)

巻号頁・発行日

vol.38, no.2, pp.114-118, 1995

---

従来の超音波ネブライザーを用いた気管支拡張剤の吸入療法では二, 三の薬物において, 薬剤含量が低下することを報告してきた。今回, 新規に開発されたダブルホーン型超音波ネブライザーを用いて, 気管支拡張剤の安定性改善にっいて検討した。新規超音波ネブライザーを用いた噴霧では, いずれの気管支拡張剤においても, 噴霧液ならびにボトル内残液の外観変化および含量低下は認められず, 薬剤の安定性が保持されていた。以上のことより, 気管支拡張剤の吸入療法に際して, 新規に開発されたダブルホーン型超音波ネブライザーを用いることの有用性が示唆され, 今後, 超音波吸入療法の機器として広く臨床使用されることが期待される。

著者

栗田 かほる 望月 優花 国分 秀也 厚田 幸一郎

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.135, no.11, pp.1307-1315, 2015 (Released:2015-11-01)

参考文献数

14

被引用文献数

2

---

The dose of a transdermal fentanyl patch is proportional to its application site area. Therefore, the absorption of fentanyl may decrease if the patch detaches, leading to insufficient analgesia. Sixteen healthy volunteers were enrolled in a study to investigate the appropriate application sites and clinical utility of three transdermal fentanyl patches available in Japan. Three placebos, Fentanyl 1-day (Fentos; Fen), Fentanyl 3-day (Durotep; Dur), and Generic Fentanyl 3-day (HMT) were administered using a crossover study design. The placebos were applied to 11 different sites, including both sides of the upper arm, abdomen, back, thigh, chest, and the middle of the chest. We determined the patch detachment area and incidence of patch-induced itching every 24 h and evaluated differences between each application site using the Wilcoxon signed-rank test. Significant patch detachment was observed on the abdomen and upper arms with Fen, on the abdomen and chest with Dur, and on the chest with HMT compared with that at other sites (p<0.005). Although no significant difference in itching was observed between regions when administering Fen, itching significantly increased on the chest and back when using Dur and on the abdomen when using HMT as compared with that at other sites (p<0.05). Our results indicate that the three transdermal Fen patches exhibit different adhesive properties and local adverse events, indicating that the application site should be cautiously selected for each patch type.

著者

小林 義和 齋藤 雅俊 藤野 玲子 西 真由美 柴田 壮一 厚田 幸一郎

出版者

一般社団法人日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.15, no.2, pp.90-96, 2013 (Released:2013-09-05)

参考文献数

5

---

Objective: As part of the revision on remuneration for medical services in 2012, a new system has been implemented to allow an additional fee for inpatient pharmaceutical services to be added to the basic hospitalization fee.Methods: We at Kitasato University Kitasato Institute Hospital satisfied all institutional requirements for the new system and were preparing to introduce it from April 2012; however, there was concern about the increased workload due to the additional work of preparing diaries for pharmaceutical services used in calculating the additional fee.Results: We therefore developed a database titled Diary System for Inpatient Pharmaceutical Services for the preparation and management of diaries.  This system allows pharmacists from various divisions to enter data simultaneously and realizes the unified management of records of services performed at various places in the pharmacy.Conclusions: Since entered data are automatically reflected in the inpatient pharmaceutical service diary and the monthly summary, an advantage compared to paper diaries in terms of efficiency may be expected.  Furthermore, the monthly summary of the number of service hours by ward and service type may also be used for service analysis.

著者

吉山 友二 尾鳥 勝也 厚田 幸一郎 矢後 和夫 藤金 治雄 緒方 憲太郎 二神 幸次郎

出版者

日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.33, no.4, pp.365-369, 2007-04-10

被引用文献数

2

---

Elcatonin injection is used for the treatment of osteoporosis in Japan. In order to compare the original product with generic versions, we measured the elcatonin content and amounts of impurities in both using high performance liquid chromatography, and observed changes in content with time under the conditions of light exposure and shaking. We found that elcatonin content and amounts of impurities varied among the generics and that changes in content with time under the above conditions for some generics were greater than the changes for the original product. These results suggest that some generic products should not be considered to be equivalent to the original product.