著者

小宮 秀明 佐々木 絵未 黒川 修行

出版者

一般社団法人 日本体育学会

雑誌

体育学研究 (ISSN:04846710)

巻号頁・発行日

vol.61, no.1, pp.29-42, 2016 (Released:2016-06-17)

参考文献数

19

被引用文献数

1

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High/low alcohol tolerance is determined by genetic polymorphisms of ADH2 and ALDH2. Currently, operators conduct ethanol patch testing for assessment of alcohol tolerance in a subjective manner; therefore, the test results may vary among individuals. The present study was designed to verify the reliability of ethanol patch testing, with a focus on changes in skin color due to seasons. Two operators were assigned to perform ethanol patch tests, and alcohol-related genetic polymorphisms were evaluated to verify the results.  The study included 129 healthy students from Utsunomiya University (age range: 21-24 years). These students were selected because they met the eligibility criteria for the study (all necessary information had to be available, i.e. results for all questionnaire items and patch tests, as well as genetic analysis). Alcohol-related genes tested in this study were ADH2 and ALDH2. During the ethanol patch tests, two operators examined the subjects' cutaneous reactions immediately after lint pad had been removed from their skin, and at 10 min after removal.  Ethanol patch test to the subjects was performed twice: once in summer and once in winter. We also administered a questionnaire to assess the students' views on alcohol and drinking habits. According to the cutaneous reactions examined at 10 min, there was significant concordance between the results of ethanol patch tests and ALDH2 genetic polymorphisms. The results of the patch tests performed by the 2 operators (A and B) in summer showed that the concordance rate between the operators was 93.8% (κ coefficient: 0.889; 95% confidence interval: 0.815-0.962, p<0.001) for the cutaneous reactions at 10 min after lint pad removal. Moreover, the same operator's data showed that the concordance rate between the results of the summer and winter patch tests was 70% or higher. These findings suggest that ethanol patch testing is a reliable assay of alcohol tolerance, although the results may be influenced by seasons and individual operator subjectivity. Therefore, during ethanol patch tests, it is important to take into account test conditions such as the time of year and skin color, and to evaluate the results comprehensively.

著者

黒川 修行 小宮 秀明 宇佐見 隆廣 佐伯 圭一郎

出版者

学術雑誌目次速報データベース由来

雑誌

学校保健研究 (ISSN:03869598)

巻号頁・発行日

vol.40, pp.308-316, 1998

被引用文献数

9

著者

小宮 秀明 森 豊 黒川 修行

出版者

宇都宮大学

雑誌

基盤研究(C)

巻号頁・発行日

2011

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これまで内臓脂肪面積(VFA)と肥満関連遺伝子との関連性についての報告はない.今回は肥満関連遺伝子としてB3AR、B2ARやUCP1を用い、VFAの蓄積に及ぼす肥満関連遺伝子の影響について検討した.被験者は男性81名、女性186名である.測定項目はVFA、腹囲、血糖、血清脂質、血圧である.アンケートは生活習慣、食習慣及び運動習慣である.3遺伝子の多型別にVFAを比較した結果、有意差は認められなかった.また、年齢、運動習慣、歩行量を調整した分析においても多型間に有意差は見られなかった.一方、男性においては運動習慣との間に有意差が確認され、運動の実施がVFAの減少に影響を及ぼすことが示唆された.

著者

鈴木 正寛 佐藤 崇 小宮 秀明

出版者

理学療法科学学会

雑誌

理学療法科学 (ISSN:13411667)

巻号頁・発行日

vol.28, no.3, pp.389-393, 2013 (Released:2013-07-16)

参考文献数

18

被引用文献数

3 1

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〔目的〕本研究は局所筋群に運動を負荷し,運動後の骨格筋の硬化と筋肉痛との関係について検討を行った.〔対象〕健康な男子学生9名を対象とした.〔方法〕腕エルゴ装置を用いて運動負荷試験を実施し,安静時と運動終了後3日間の皮下脂肪厚,筋厚,上腕周径囲,筋硬度,筋肉痛,MVCを測定した.〔結果〕筋硬度,腫脹は運動終了直後から急激な変化を認め,その後2,3日をかけて回復する傾向を確認した.筋肉痛は,運動終了1日後及び2日後に有意な増加を示した.〔結語〕筋硬度,筋厚及び上腕周径囲の増加の要因として組織水の貯留といった循環機能の低下が示唆された.また,運動終了1日後及び2日後のパフォーマンス低下には筋肉痛を主とする知覚神経の影響が推察された.

著者

小宮 秀明 前田 順一 竹宮 隆

出版者

日本体力医学会

雑誌

体力科學 (ISSN:0039906X)

巻号頁・発行日

vol.44, no.6, 1995-12-01

著者

小宮 秀明 黒川 修行

出版者

一般社団法人 日本体育学会

雑誌

体育学研究 (ISSN:04846710)

巻号頁・発行日

vol.63, no.2, pp.495-504, 2018-12-10 (Released:2018-12-20)

参考文献数

23

被引用文献数

1

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Being overweight is a major risk factor for development of lifestyle-related diseases, and the sheer volume of current evidence that childhood obesity persists into adolescence and adulthood suggests the importance of rectifying obesity in childhood. The present study followed up children in the 1st to 6th grades of elementary school to examine whether being overweight was a continuous trend. In addition, increases and decreases in the adiposity of the students were examined in order to clarify fluctuations in their physical build. The subjects of the study were 3991 students (2046 boys and 1945 girls) attending all 68 schools in city U who were tracked for 6 years. The students were divided into 10th percentiles based on their degree of overweight. Using the median 45-55th percentile as a reference group, univariate logistic analysis was used to calculate the odds ratio of students who were overweight in the 1st grade remaining so in the 6th grade. It became clear that students in the 85th percentile or higher in first grade were 39.8 times more likely for boys and 21.9 times more likely for girls to be overweight in the 6th grade than 1st grade students in the reference group. Boys and girls who were markedly overweight in the 1st grade continued to demonstrate high degrees of obesity in the 6th grade. About 80% of both boys and girls who were overweight in the 1st grade of elementary school continued to be overweight in the 6th grade. Based on the above findings, it is clear that the degree of overweight in the 1st grade of elementary school has a strong influence on the corresponding degree in the 2nd grade and thereafter, thus suggesting the importance of preventing overweight developing upon entry to elementary school.