著者

高木 久 福田 俊 飯田 治三 佐藤 淳 佐藤 れえ子 内藤 善久

出版者

社団法人日本獣医学会

雑誌

The journal of veterinary medical science (ISSN:09167250)

巻号頁・発行日

vol.58, no.4, pp.311-316, 1996-04-25

被引用文献数

4

---

ビタミンAD_3E(V-AD_3E)の合剤, ビタミンA(V-A)あるいはビタミンD_3(V-D_3)の単剤を哺乳期の子牛へ生後7日齢から10日間大量経口投与し, 牛ハイエナ病の発症試験を実施したところ, V-AD_3E剤(日量V-A 300万I.U., V-D_3 30万I.U., V-E1, 200I.U.)を投与したV-AD_3E群(2頭中2頭), その半量を投与したHalf V-AD_3E群(2頭中1頭), およびV-A 300万I.U.を投与したV-A群(2頭中1頭)の計4頭に発症が認められたが, V-D_3 30万I.U.を投与したV-D_3群では観察されなかった. 発症子牛では, V-Aの過剰を示す血中のエステル型のV-A(レチニルパルミテート)が高値を示し, 長骨の成長軟骨板は狭窄や構造の変性などを示した. V-AD_3E群はV-A群と比較して, 発症年齢が早く, 体重増加率の低下および後肢だけでなく前肢の成長不全も重度であった. 以上, 牛ハイエナ病は, 子牛の成長軟骨板に対する過剰なV-Aの作用により発症し, さらにV-D_3によって発症が促進されるものと推測された.

著者

So-Jeung MOON Ju-Won KIM Byeong-Teck KANG Chae-Young LIM Hee-Myung PARK

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.3, pp.361-366, 2012 (Released:2012-04-03)

参考文献数

21

被引用文献数

9 11

---

A 6-year-old ShihTzu presented with tonic-clonic cluster seizure. T2-weighted magnetic resonance (MR) images showed bilateral diffuse hyperintense lesions at the cerebral cortex with enlarged sulci. Computed tomography revealed a portosystemic shunt (PSS) and azygos continuation. Based on the clinical signs, blood examinations and diagnostic images, the dog was diagnosed with hepatic encephalopathy secondary to PSS. The neurologic signs were gradually improved after medical therapy for hyperammonemia. This is the first report of hyperintensity of the cerebral cortex on T2-weighted MR images associated with acute hepatic encephalopathy in a dog.

著者

Hyejin KIM Heeyeon CHOI Hyunwook KIM Jihye CHOI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.3, pp.385-389, 2012 (Released:2012-04-03)

参考文献数

17

被引用文献数

2 4

---

A 13-year old intact female poodle showed persistent signs of estrus. Ultrasonographically, a large cystic mass containing echogenic fluid with a thin wall was observed, and it was 8 cm in diameter. The cystic mass was located at the mesovarium between the left ovary and uterine horn, and it was identified as a giant parovarian cyst. A right ovarian mass was histologically diagnosed as a granulosa cell tumor. Persistent estrogen hormone secretion by the granulosa cell tumor was thought to cause a rapid increase in the size of the parovarian cyst. This rare cystic mass originated from the genital system and was differentiated from the uterus.

著者

Rokusuke YOSHIKAWA Eiji SATO Takayuki MIYAZAWA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.3, pp.347-350, 2012 (Released:2012-04-03)

参考文献数

16

被引用文献数

4 5

---

We recently found that certain canine live attenuated vaccines produced using `non-feline' cell lines were contaminated with an infectious feline endogenous retrovirus, termed RD-114 virus. We suspected that RD-114 virus may have contaminated the seed stock of canine parvovirus (CPV) during the production of the contaminated vaccines. In this study, we collected stock viruses of CPVs propagated in a feline cell line, and checked the presence of infectious RD-114 virus. Consequently, we found that RD-114 viral RNA was present in all stock viruses, and 7 out of 18 stock viruses were contaminated with infectious RD-114 virus. We also found that RD-114 virus was stable physically and is capable of retaining its infectivity for a long period at -80°C.

著者

Josué DÍAZ-Delgado Manuel ARBELO Simona SACCHINI Óscar QUESADA-CANALES Marisa ANDRADA Miguel RIVERO Antonio FERNÁNDEZ

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1203280799, (Released:2012-04-02)

被引用文献数

4 10

---

Vascular tumors and disorders, like angiomatosis, are rarely described in cetacean species. A retrospective histological study was carried out on lung samples from 35 common dolphins (Delphinus delphis) stranded in the Canary Islands coasts looking for morphological vascular changes and likely related causes. Twenty-five out of thirty-five (71%) common dolphins showed focal or multifocal angiomatosis-like lesions. A high association between this type of vascular proliferation and parasitic infestation was observed. In addition, a single pulmonary cavernous hemangioma not previously reported in common dolphins is presented.

著者

Kenji KOROSUE Harutaka MURASE Fumio SATO Mutsuki ISHIMARU Takehiro HARADA Gen WATANABE Kazuyoshi TAYA Yasuo NAMBO

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1203280800, (Released:2012-04-02)

被引用文献数

5 11

---

The purpose of this study was to demonstrate that a barren parous Thoroughbred mare with lactation induced by hormonal treatment can be introduced to an orphan foal at the same farm and that the mare can become pregnant after the end of the hormonal treatment. An additional purpose was to investigate the changes in the plasma concentrations of prolactin, estradiol-17β, progesterone, follicle-stimulating hormone, and luteinizing hormone before, during, and after hormonal treatment. The difference in body weight between the adopted foal and the control foals, which were at the same farm and raised by their natural mothers, was 17 kg at 24 weeks old, when the foals were weaned. However, the adopted foal and the control foals had almost the same weight at 35 weeks old and later. The first ovulation after hormonal treatment was confirmed 10 days after the end of hormonal treatment and then the normal estrous cycle resumed. Furthermore, the changes in plasma progesterone, estradiol-17β, follicle-stimulating hormone, and luteinizing hormone showed regular patterns after the first ovulation. Conception was confirmed in the fifth ovulation. Meanwhile, another study demonstrated that conception was confirmed in the first ovulation after hormonal treatment. The present study is the first to demonstrate the hormonal profiles during and after induction of lactation in a Thoroughbred mare. This approach is useful for solving the economic and epidemic problems of introducing a nurse mare to an orphan foal.

著者

Nian-Zhang ZHANG Yue-Feng CHU Peng-Cheng GAO Ping ZHAO Ying HE Zhong-Xin LU

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1203180795, (Released:2012-03-26)

被引用文献数

5 11

---

Haemophius parasuis is known to produce a group of virulence-associated autotransporter (AT) proteins, VtaAs; however, no other ATs have been characterized yet. On the basis of reported sequence of a putative espP2 gene for extracellular serine protease (ESP)-like protein of H. parasuis, this putative AT gene was successfully amplified from H. parasuis serotype 5 field strain HPS0819, cloned and sequenced. The confirmed ORF sequence showed 100% identity with the reported putative espP2 gene. The recombinant ESP-like protein purified from Escherichia coli with pET expression system was used for immunological characterization. An approximately 85 kDa antigen was detected in cultured H. parasuis by using antiserum to the purified ESP-like protein and antibodies against the recombinant ESP-like protein was detected in a selected serum from pigs with experimental H. parasuis infection. The results indicated that H. parasuis could produce ESP-like protein in vitro and in vivo. In an immune protection study using guinea pigs, 6 out of 10 animals immunized with the recombinant ESP-like protein survived after challenge with 5×109 bacteria of strain HPS0819 whereas 7 out of 10 animals immunized with formalin-inactivated H0819 bacterin survived after challenge. The results suggest that ESP-like protein could be one of vaccine antigen candidates for H. parasuis infection.

著者

Qin-Fan LI Cai-Ju HAO Yong-Ping XU Jie LIANG Kai YANG Zhong-Hua CUI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1203220797, (Released:2012-03-26)

被引用文献数

5 8

---

By a series of experiments, we identified a new member of locoweed family, Oxytropis serioopetala, which produces swainsonine, a phytotoxin harmful to livestock. In order to evaluate the toxicity of Oxytropis serioopetala, its extract was administered to ten rabbits by gavage at a dose of 1.5 mg/kg body weight as swainsonine once daily. After the 20th day, the rabbits appeared depressive and anorexia. Besides, intention tremors were apparent upon move. Their eyes were dull. The rear limbs were severely weak and even progressed to partial paresis. Activities of serum aspartate aminotransferase (AST), alanine transaminase (ALT), alkaline phosphatase (AKP) and urea nitrogen (BUN) levels in the poisoned rabbits increased significantly. Serum α-mannosidase (AMA) activity decreased markedly. Pathomorphological lesions in the locoweed-poisoned rabbits developed severe microvacuolation of visceral and neurological tissue. The extensive vacuolation was observed in liver, kidney and brain. These clinical and pathological features are similar to the symptoms of locoism.

著者

Sung Min NAM Sun Shin YI Dae Young YOO Woosuk KIM Jung Hoon CHOI In Koo HWANG Je Kyung SEONG Yeo Sung YOON

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1203110792, (Released:2012-03-21)

被引用文献数

3 4

---

In this study, we investigated diabetic stage dependent cyclooxygenase-2 (COX-2) immunoreactivity in the dentate gyrus in streptozotocin (STZ)-induced type 1 diabetic rats. The animals were sacrificed at 2, 3 and 4 weeks after STZ treatment. Blood glucose levels were increased after STZ treatment. COX-2 immunoreactivity in dentate gyrus was significantly increased in these regions 3 weeks after STZ treatment and restored to its basal level to 4 weeks after STZ treatment. In contrast, COX-2 immunoreactivity was not changed in CA3 region in all groups. These results suggest that STZ-induced type 1 diabetes transiently, but not permanently, decreased synaptic transmission and plasticity 3 weeks after STZ treatment in the dentate gyrus.

著者

Nao TSUZUKI Jong-Pil SEO Kazutaka YAMADA Shingo HANEDA Yasuhiko TABATA Naoki SASAKI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1203160793, (Released:2012-03-22)

被引用文献数

5 8

---

Platelet-rich plasma (PRP) was administered to cattle with hoof defects (10-mm drill hole) to promote sole defect healing. Two types of gels were prepared. One was a mixed gel [compound of gelatin microspheres (GM) incorporated with PRP and alginate] and was used for the test group, while the other was an alginate gel used for the control group. Each hole was filled with one of these gels. The drill hole depth, pressure pain, and hardness of the regenerated tissue were measured for 3 weeks after treatment. These measurements improved significantly in the test group than in the control group. The results suggest that a compound of GM incorporated with PRP and alginate had a hoof-regenerating effect in cattle.

著者

Seung Bin CHA An Na YOO Won Jung LEE Min Kyoung SHIN Myung Hwan JUNG Seung Won SHIN Young Wook CHO Han Sang YOO

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1203110791, (Released:2012-03-21)

被引用文献数

7 28

---

We evaluated effect of enterotoxigenic Escherichia coli (ETEC) specific lytic phage CJ12 in ETEC infected pigs. Phage was mixed with feed at a ratio of 1:1,000 (0.1%). One week after initially providing phage mixed feed, pigs were challenged orally with 1011 CFU of ETEC and body weight, diarrhea score, bacterial CFU and phage PFU in the feces were measured. Pigs of phage treated groups C (106 PFU/g) and D (108 PFU/g) showed more resistance to diarrhea due to ETEC infection compared to positive control group B on the third day after the initial challenge. Moreover, during the quantitation of ETEC in feces, both groups C and D showed approximately 63.92 and 60.73% reduced ETEC compared to positive control group B. Phages were successfully isolated from feces in both groups C and D during the experiment without any adverse effects, suggesting the possibility of using CJ12 as a feed additive.

著者

Sayumi SHIMODE Takayuki MIYAZAWA Takeshi KOBAYASHI Hisaaki SATO Taishi TANABE

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.2, pp.235-239, 2012 (Released:2012-03-02)

参考文献数

21

---

Interferon-stimulated gene 15 (ISG15) is one of the type I interferon-inducible proteins. Addition of ISG15 known as ISGylation is an ubiquitin-like posttranslational modification. Coexpression of ISG15 and ubiquitin-activating enzyme E1-like protein (UBE1L) is required to induce ISGylation. Previously, we identified feline ISG15 gene and found that the capsid protein of feline immunodeficiency virus was ISGylated in vitro by treatment with feline interferon-ω. In this study, we cloned feline UBE1L (FeUBE1L) gene to further study the mechanism of the antiviral activities induced by ISGylation. Sequencing analysis revealed that active sites of FeUBE1L were highly conserved. These data suggest that FeUBE1L has an enzymatic activity. Further, expression of FeUBE1L was induced in feline cell lines by treatment with feline interferon-ω and ovine interferon-τ.

著者

Eiichi KAWAKAMI Tomoko YAGI Masanori KOBAYASHI Tatsuya HORI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.2, pp.201-204, 2012 (Released:2012-03-02)

参考文献数

14

被引用文献数

2 2

---

A Beagle dog (3 years old) that ejaculated high percentages (mean ± SE: 29.1 ± 1.2%) of sperm with a knobbed acrosome abnormality and a low number of sperm and that also had a low plasma testosterone (T) level was given 10 subcutaneous injections of 1 μg of gonadotropin-releasing hormone analogue (GnRH-A) at 3-day intervals. The plasma T level and number of sperm increased 12-14 weeks after the first injection. Although the percentages of sperm with knobbed acrosome abnormality did not change after the GnRH-A therapy, the number of sperm and percentage of actively motile sperm increased after the therapy, and a bitch gave birth to 5 healthy puppies after intravaginal artificial insemination with fresh semen collected 14 weeks after the first injection.

著者

Kohei SAEKI Yoshifumi ENDO Kazuyuki UCHIDA Ryohei NISHIMURA Nobuo SASAKI Takayuki NAKAGAWA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.2, pp.227-230, 2012 (Released:2012-03-02)

参考文献数

34

被引用文献数

8 13

---

The numbers of tumor infiltrating T lymphocytes, B lymphocytes and antigen presenting cells were evaluated in an immunohistochemical manner in 140 canine spontaneous mammary gland tumor (MGT) tissues. As a result, we found a statistically significant increase in the number of intratumoral T lymphocytes (23.2 ± 23.8) in the malignant MGT group (n=51) compared with the benign MGT group (14.0 ± 16.0, n=89; P<0.05). Moreover, the high T lymphocyte infiltration in the malignant group correlated with poor prognosis in multivariate analysis (P<0.05). This study indicated the relationship between increased infiltrating T lymphocytes and canine MGT malignancy.

著者

Naohito NISHII Haruka MAEDA Yusuke MURAHATA Aya MATSUU Yoshiaki HIKASA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.2, pp.267-269, 2012 (Released:2012-03-02)

参考文献数

19

被引用文献数

2 4

---

The effect of experimental hyperlipemia on insulin sensitivity was evaluated in seven healthy cats. Serum triglyceride and free fatty acid concentrations were significantly (P<0.05) higher when lipid-heparin was administered (2,894 ± 1,526 mg/dl and 4.54 ± 0.70 mEq/l, respectively) than when saline was administered (70 ± 42 mg/dl and 0.22 ± 0.08 mEq/l, respectively). A glucose clamp test revealed that the mean glucose infusion rate when lipid-heparin was administered (5.80 ± 0.67 mg/kg/min) was significantly (P<0.05) lower than when saline was administered (8.52 ± 1.83 mg/kg/min). These results suggest that experimental hyperlipemia induced insulin resistance in the healthy cats.

著者

Ryota NOMURA Mitsuyuki SHIRAI Yukio KATO Masaru MURAKAMI Kazuhiko NAKANO Norihiko HIRAI Tetsuya MIZUSAWA Shuhei NAKA Yoshie YAMASAKI Michiyo MATSUMOTO-NAKANO Takashi OOSHIMA Fumitoshi ASAI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1202220780, (Released:2012-03-02)

被引用文献数

8 16

---

Porphyromonas gulae, a gram-negative black-pigmented anaerobe, is a pathogen for periodontitis in dogs. An approximately 41-kDa fimbrial subunit protein (FimA) encoded by fimA is regarded as associated with periodontitis. In the present study, the fimA genes of 17 P. gulae strains were sequenced, and classified into two major types. The generation of phylogenetic trees based on the deduced amino acid sequence of FimA of P. gulae strains along with sequences from several strains of Porphyromonas gingivalis, a major cause of human periodontitis, revealed that the two types of FimA (types A and B) of P. gulae were similar to type I FimA and types II and III FimA of P. gingivalis, respectively. A PCR system for classification was established based on differences in the nucleotide sequences of the fimA genes. Analysis of 115 P. gulae-positive oral swab specimens from dogs revealed that 42.6, 22.6, and 26.1% of them contained type A, type B, and both type A and B fimA genes, respectively. Experiments with a mouse abscess model demonstrated that the strains with type B fimA caused significantly greater systemic inflammation than those with type A. These results suggest that the FimA proteins of P. gulae are diverse with two major types and that strains with type B fimA could be more virulent.

著者

Ai WATABE Kiwamu HANAZONO Takahiro KOMATSU Dah-renn FU Yoshifumi ENDO Tsuyoshi KADOSAWA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1202220779, (Released:2012-03-02)

被引用文献数

2 4

---

To evaluate the relationship among immune status and increased morbidity and mortality, peripheral blood lymphocytes (CD3+, CD4+, CD8+, CD21+ cells) from 32 healthy dogs aged over 8 years were analyzed. Twenty-five dogs out of 32 were followed-up for 3 years after the analysis, and 14 dogs were found to be diseased and nine dogs died. There was no notable difference between the age of dogs that died compared with the ones that survived. The relative percentage of CD4+ and CD4+:CD8+ ratio decreased notably in dogs falling ill compared with healthy dogs. The relative percentage of CD3+ lymphocytes showed a notable decrease in dogs that died within 3 years in comparison with dogs that survived. In a discriminant analysis of morbidity and mortality, most patients were correctly classified as diseased or not and surving or dead, respectively. These results indicate that the immunophenotypes of peripheral blood lymphocytes in older dogs offer promise as parameters for evaluating mortality and morbidity.

著者

Jong Kil LEE So Young CHUN Jin Young IM Hee Kyung JIN Tae Gyun KWON Jae-Sung BAE

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1203070789, (Released:2012-03-14)

被引用文献数

1 4

---

Stem cell based cell therapies offer significant potential for the field of regenerative medicine. Human amniotic fluid stem cells (hAFSCs) are an attractive source for lineage-specific differentiated stem cell therapy since they have properties that are able to differentiate into cells representing all three germ layers. To better understand the fate and location of implanted hAFSCs, a means to monitor cells in living subjects is essential. Here, we showed that differentiated cells, such as neurogenic, endothelial, and myogenic cells, derived from hAFSCs can be effectively labeled by the FITC-incorporated silica-coated nanoparticles, MNPs@SiO2 (FITC), although the labeling efficacy and cytotoxicity were distinct depending on the differentiated cell type. In addition, we observed that MNPs@SiO2-labeled cells provided sufficient signals for detection by optical and confocal microscope imaging when transplanted into the mice. These results suggest that the fluorescent dye incorporated MNPs@SiO2 are a useful tool for the cell labeling and in vivo tracking of differentiated cells derived from hAFSCs.

著者

平野 孝一 足立 吉數 Bintvihok Anong 石橋 幸子 熊澤 教眞

出版者

社団法人日本獣医学会

雑誌

日本獣医学雑誌 (ISSN:09167250)

巻号頁・発行日

vol.54, no.3, pp.567-569, 1992-06-15

---

肝臓からの効果的なアフラトキシンの抽出及びクリンアップの方法について検討した. 先ず, アフラトキシンを破砕した肝臓から遊離させるために, プロテイナーゼKで酵素処理を行った. その試料からの回収試験では, 鶏の肝臓の場合, 高速液体クロマトグラフィー(HPLC)で108.1±4.9%(平均値±標準誤差, n=3), 酵素免疫測定法(ELISA)で, 122.0±18.3%(n=3)であった. 豚の肝臓では, HPLCで111.8±5.2%(n=3)・ELISAで120.3±9.1%(n=3)であった. さらに, 幼雛へのアフラトキシンB_1(AFB_1)の投与試験を実施し, その肝臓からの回収試験を行ったところ, 投与後3時間目に高いAFB_1値が得られ, その値は時間とともに, すみやかに低下した. このことから, アフラトキシン汚染飼料を摂取した鶏においては, 少なくともアフラトキシン摂取後24時間以内ならば肝臓から検出可能との知見が得られた. この抽出及びクリンアップの方法を用いて, 血漿からアフラトキシンが検出された野外飼育採卵鶏の肝臓36検体と屠畜場から入手した豚の肝臓6検体及びそれらの豚が食べていた飼料6検体からアフラトキシンの検出を試みたが, いずれの試料からもHPLC及びELISAによってアフラトキシンは検出されなかった.

著者

Daiki MURATA Naoki MIURA Tomoko IWANAGA Satoshi TOKUNAGA Noriaki MIYOSHI Yoshiaki KITANO Yasuyuki MOMOI Makoto FUJIKI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1201280767, (Released:2012-02-08)

被引用文献数

3 4

---

A 12-year-old neutered male shih tzu developed progressive pelvic limb paraparesis. Computed tomography showed a radiolucent mass lesion in the spinal canal at the left side of the 11th thoracic vertebra. The mass was not enhanced by intravenous contrast medium injection. It was hyperintense on both T1- and T2-weighted magnetic resonance images. The signal intensity of the mass was decreased with a fat suppression technique, indicating a fatty origin. After removal of the mass via T11–T12 hemilaminectomy, chronic panniculitis was confirmed by histopathological examination. This case demonstrates the utility of computed tomography and magnetic resonance imaging for the diagnosis of spinal canal pyogranulomatous inflammation.