著者

池田 嘉一郎

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.32, no.371, pp.646-666, 1920-12-31

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(一)所謂人乳中毒症ニ於ケル精紳症状ハ、輕症ナルモノニ於テハ、一過性ノ興奮性充進竝ニ嗜眠状態ヲ呈スルニ過ギザルモ、重症ナルモノニ於テハ、更ニ進ミテ意識溷濁乃至無慾状顔貌ヲ呈シ、周圍ノ事情ニ對スル識別力ヲ失ヒ笑ハズ泣カズ、眼付曇ヨリシ、時トシテ舞踏病樣不隨意運動乃至不明ノ言ラ發ス、カク特異ナル精紳症状ヲ呈スルハ神經申樞ニ何等カノ病變ノ存スルモノト考ヘザルベカラズ、余ハカカル患者ニ遭遇スル毎ニ勉メテ腰椎穿刺ヲ行ヒ腦脊髓液ノ性状ヲ檢シタルニ、ソノ外觀、比重、糖反應、蛋白量、蜘蛛網状物形成ノ有無等ノ關係ハ、多クハ健康者ノモノト差異ヲ認ムルコト能ハザリシモ、「グロブリン」反應及ビ細胞數ニ於テ輕微ノ變化ノ存スルヲ認メタリ、即チ「グロブリン」反應中、ノンネーアツペルト氏反應竝ニパンヂー氏反應ハ多クハ陰性(時トシテ弱陽性ナルコトアリ)ナルモ野口氏反應ハ毎常弱陽性ヲ示セリ、而シテ淋巴球ノ數ハ通常ナルカ或ハ僅ニ増加セリ、即チ輕度ノ漿液性腦膜炎ノ腦脊髓液ニ相類似ス、カカル腦脊髓液ノ變化ハ唐澤博士ノ報告セル軟腦膜ニ於ケル解剖的變化ト相符合ス。(二)臨牀上ニ於ケル所謂人乳中毒症ト乳兒脚氣トノ主要ナル區別點ハ、伊東博士ニ依レバ血行器症状竝ニ精神症状ノ有無ニ存ス、然レドモ血行器症状ハ兩疾患ヲ鑑別スルニ向ツテ爾カク重要ナル資料トナスヲ得ズ、蓋シ血行器症状ハ乳兒脚氣ニ於ケル必要ナル症状ノ一ツナルモ而モ之ヲ伴ハザルモノ稀ナラズ、又所謂人乳中毒症ニ於テモ血行器症状ハ必ラズ缺如スベキモノニアラザルガ故ナリ、況ンヤ症例(三)ニ於ケルガ如ク、所謂人乳中毒症ニ於テ其ノ經渦中ニ突然衝心症状ヲ表ハシタル事實アルエ於テオヤ。精神症状ノ有無ニ至リテハ、吾人ハ兩疾患ニ於ケル最モ顯著ナル差異タルヲ是認セザルベカラズ、然レドモ大人脚氣ニ於テ稀ニ精神症状ヲ伴フコトアルコト竝ニ余ノ實驗例ノ如ク幼兒脚氣ニ於テ躁暴狂状乃至昏迷ヲ呈シ、而モ軟腦膜ノ病理解剖的所見ニ於テ所謂人乳中毒症ト殆ド同樣ナル病變ヲ呈セルコトアル事實ヨリ推考スル時ハ、乳兒脚氣ニアリテモ亦精神症状ノ表ハルルコトアリテ可ナル理ナリ。(三)所謂人乳中毒症ト母體脚氣トハ甚ダ密接ナル關係ヲ有スルハ余ノ統計的觀察ニ依リテ明カナリ、余ノ症例(四)及ピ(五)ハ正シクコノ事實ヲ立證セルモスト云フヲ得ベシ、即チ余ノ症例ハ哺乳ノ時期ヲ異ニスルモ、脚氣ヲ有スル同一母體ノ乳汁ヲ哺乳シタルニ依リテ、第四子ハ乳兒脚氣ヲ惹起シ、第五子ハ所謂人乳中毒症ヲ惹起セルモノトス、カカル事實ハ、所謂人乳中毒症ハ其ノ本態ニ於テ乳兒脚氣症ト同一ナルモノニアラズヤトノ疑念ヲ益々吾人ニ抱カシム。(四)以上ノ事實ヲ綜合スル時ハ、所謂人乳中毒症ハ其ノ本態ニ於テ乳兒脚氣ト同一上ニ立ツベキ疾患ニシテ、詳言セバ乳兒脚氣ノ一異型ト見做スベキモノナリト信ズ、余思ヘラク、乳兒脚氣ハ脚氣毒素ガ母體ノ乳汁ヲ介シテ小兒ニ移行スルニ依リテ起ル一種ノ中毒症ニ外ナラズ、而シテ臨牀上ニ於テ一方ニハ專ラ心臓機能ヲ障碍スル衝心型アリ又他方ニ血行器症状ヲ件ハズシテ専ラ末梢神經ヲ侵ス所ノ麻痺型ナルモノアリ、コレ等ノ事實ヨリ考フル時ハ脚氣毒素ガ主トシテ心臓ヲ侵ス時ハ衝心型トナリテ表ハレ、主トシテ末梢神經ヲ侵ス時ハ麻痺型トナリテ表ハレ、專ラ腦膜ヲ侵ス時ハ所謂人乳中毒症ノ型トナリテ表ハルルモノニアラザルカ、カカル關係ハカノ麻疹ノ例ニ於テ之ヲ見ル、即チ症状ノ劇烈ナルモノニ於テハ、多クハ肺炎ヲ合併シコレト同時ニ心臓衰弱ヲ招來スルモ、時トシテハ主トシテ中樞神經系統ニ障碍ヲ及ボシ、既ニ前驅期或ハ發疹期ノ初メニ於テ意識溷濁ヲ來シ遂ニ無慾状態ニ陷ルコトアリ、又恢復期ニ於テ稀ニ腦膜ヲ侵シ漿液性腦膜炎ヲ惹起スルモノアリ、是レ麻疹毒ハ時ニ主トシテ中樞神經系統ヲ侵スコトアルヲ意味スルモノニシテ、以上述ベタル余ノ乳兒脚氣ニ於ケル説明ト相符合スル點アルヲ以テ茲ニ之ヲ引用シタルニ過ギズ、カク觀察シ來ル時ハ精神症状ノ有無ハ敢テ問題トナスニ足ラザルナリ、余ハ所謂人乳中毒症ヲ乳兒脚氣腦型トナシ乳兒脚氣中ニ包括スルニ賛スル者ナリ。

著者

佐藤 智昭 上島 智 千堂 年昭

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.119, no.2, pp.199-203, 2007-09-03 (Released:2008-07-04)

参考文献数

15

著者

岡崎 昌一

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.72, no.5, pp.1351-1357, 1960-07-30

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By selecting 4 oxime compounds possessing pyridine nucleus in the molecular construction, namely, PATD, PPATD, PPAPD, and PAD, the author compared their therapeutic effects on alkylphosphate poisoning with the effect of PAM. 1. As for the therapeutic effect on alkylphosphate poisoning in mice, when administered in the maximum safety dose, PATD and PPATD are superior to PAM, but on scrutinous examinations there can be recognized not any significant difference. Effect of PPAPD is about the same as that of PAM. 2. Both PAM and PATD are most effective when administered concurrently with the intravenous administration of alkylphosphate, but as the time before or after the administration of alkylphosphate lengthens, the effect of drugs decreases proportionately. 3. Atropine used concurrently with these oxime compounds yields no better results than without it. 4. The effect of PATD is slightly more lasting than PAM, but the difference is not significant. 5. PATD has been proven to possess a reactivating action on rabbit blood cholinesterase just as PAM. Consequently it is assumed that the effective mechanism of both drugs is same. 6. When an equal dose of PAD and PAM is administered to the mice with ethylparathion poisoning, PAD is inferior to PAM in improving the mortality rate of the mice. 7. There seems to be no benefit in administering intramuscularly 15 mg/kg PAD concurrently with the administration of various oximes.

著者

伊達 勲

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.128, no.1, pp.69-70, 2016-04-01 (Released:2016-05-02)

著者

田澤 大 矢野 修也 吉田 亮介 山崎 泰源 佐々木 剛 橋本 悠里 黒田 新士 大内 正明 大西 哲平 宇野 太 香川 俊輔 浦田 泰生 藤原 俊義

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.125, no.3, pp.195-199, 2013-12-02 (Released:2014-01-06)

参考文献数

13

著者

児島 亨 渡邉 雄一 橋本 悠里 黒田 新士 山崎 泰源 矢野 修也 田澤 大 宇野 太 香川 俊輔 田中 紀章 浦田 泰生 藤原 俊義

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.125, no.1, pp.9-12, 2013-04-01 (Released:2013-05-01)

参考文献数

9

著者

大重 彌吉

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.66, no.5, pp.951-957, 1954-05-31 (Released:2009-08-24)

参考文献数

13

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From the data gathered by myself and other investigators up to 1954 in every district of Japan, I have chosen those of the mother population according to the law of X2-distribution and from their average value have concluded that the corrected frequency of principal psychoses in rural districts of Japan is as follows:-

著者

四方 賢一

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.123, no.3, pp.197-206, 2011-12-01 (Released:2012-01-04)

参考文献数

46

著者

水川 展吉 冨永 進 木股 敬裕 小野田 友男 野宮 重信 杉山 成史 川本 知明 山近 英樹 植野 高章 高木 慎

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.119, no.3, pp.267-272, 2008-01-04 (Released:2008-07-04)

参考文献数

10

被引用文献数

2 2

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There is a medical team approach used in many hospitals for oral cancer patients. The members are head & neck surgeons and plastic surgeons, or oral surgeons and plastic surgeons. However, in Japan, it is very difficult for oral surgeons to cooperate with head & neck surgeons, except in the case of extractions and oral health care, because both surgeons treat oral carcinomas and there is therefore a conflict in their scope of practice. We believe it desirable for head & neck surgeons to treat oral cancer patients with tumors extending to other regions, and oral surgeons should be in charge of occlusion in head and neck carcinomas. We treated two patients with oral carcinomas in collaboration with head and neck surgeons and plastic surgeons, with head & neck surgeons resecting the tumors, plastic surgeons reconstructing, and oral surgeons (dentists) taking charge of the occlusion for patients in the operating room. This collaboration resulted in patients having good position of the temporomandibular joint and occlusions after the operation. We therefore conclude that this collaborative team approach may be of benefit to the patients.

著者

松本 尚美 樋口 千草 三橋 利晴 萩谷 英大 高尾 総司 頼藤 貴志

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.134, no.1, pp.35-42, 2022-04-01 (Released:2022-05-02)

参考文献数

16

被引用文献数

1 2

著者

松岡 賢市 青山 一利 小山 幹子 橋本 大吾 朝倉 昇司 一戸 辰夫 谷本 光音 豊嶋 崇徳

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.120, no.1, pp.23-28, 2008-05-01 (Released:2008-07-08)

参考文献数

32

著者

關場 代五郎

出版者

岡山医学会

雑誌

岡山醫學會雜誌 (ISSN:00301558)

巻号頁・発行日

vol.29, no.332, pp.737-743, 1917-09-30 (Released:2009-08-24)

著者

三宅 進 宮村 能子

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.124, no.3, pp.239-241, 2012-12-03 (Released:2013-01-04)

参考文献数

5

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We herein report a case of bilateral frontal horn cysts. The infant was delivered with a low birth weight (1,710g) at 31 weeks, 0 days by emergency Cesarean section. She was severely asphyxiated and exhibited respiratory distress syndrome. Surfactant was administered, and mechanical ventilation was required until 21 days of age. Brain computed tomography (CT) at 45 days of age revealed bilateral cysts adjacent to the frontal horns of the lateral ventricles. Her growth and development were normal. At 1 and a half- years of age, she underwent brain CT again and the above-mentioned cystic abnormality had disappeared. No dilatation or irregularity of the lateral ventricles was found. Normal development and transient abnormal cystic findings in brain CT suggested a diagnosis of frontal horn cysts. Frontal horn cysts should be considered as the causes of cystic lesions of the brain.

著者

池口 豪泉

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.119, no.2, pp.153-163, 2007-09-03 (Released:2008-07-04)

参考文献数

35

被引用文献数

1

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The purpose of this study is to analyze the background factors relating to opinions on organ donation through factorial and structural comparisons between Japanese and Americans. The data were obtained from responses to a questionnaire (371 Japanese and 41 Americans).The main findings are as follows:1. Most of the factors, ‘a will for organ donation depending on a recipient’, ‘view of remains’, ‘understanding of brain death’ and so on showed significant differences between Japanese and Americans.2. Japanese had a better understanding of brain death. On the other hand, the ratio of Americans who were willing to donate an organ was higher than that of Japanese.3. It was revealed that “the approval of organ donation for the third person, not only for one's family” had an impact for having donor card showing the approval for organ donation. Furthermore, as underlying factors generating differences on organ transplant opinions, differences were found among Japanese between “approval of organ transplant” and the attitude assuming that oneself or a member of one's family was the person concerned with organ transplantation. There were also differences between Japanese and Americans on ideas about a view for life and death such as soul existence or view of remains.The argument for transplantation in Japan should consider these structural differences.

著者

吉本 弘満

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.72, no.1, pp.359-380, 1960

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The author performed quantitative analyses of the amount of urine excreted, the urine density, pH's, microprotine content, urine protein content, the amount of Donaggio reaction-positive substance, urine creatinine, uric acid, urine lactic acid, urine phosphoric acid, and the urine calcium content in the urine before and after work, selected from various groups of persons such as a group of marathon runners, a group of soldiers marching, and a group of ammunition carriers; and obtained the following results.<br>1. In the group of marathon runners whose work is thought to be relatively intense and of a comparatively short duration there can be recognized a rapid decrease in the urine content, an increase in the amount of urine microprotein and in urine protein-positive cases, an increase in the hourly excretion of Donaggio reaction-positive substance, a rapid increase in the density and hourly excretion of lactic acid, a slight decrease in the density and the hourly excretion of creatinine, an increase in the density and hourly excretion of phosphoric acid, and a decrease in the density and hourly excretion of calcium.<br>Judging these estimated values stoistically, it has become possible to obtain significant values in the Donaggio reaction and in the lactive acid with an error of less than one per cent in the hourly excretion contents and similarly significant values in the mucoprotein and phosphoric acid contents under 5 per cent deviation.<br>2. In the marching which is relatively of an intermediate degree of fatigue and of a longer duration, there can be observed a decrease in the quantity of urine, an incrase in the urine density, acidification of the pH, increase in the protein-positive cases, a transient increase and decrease in the excreation of creatinine and the hourly excretion amount, stability of the density and houly excretion of uric acid, a transient increase in the early stage uric acid, and a transient increase in the density and excretion of phosphoric acid. Namely, the substance estimated in this group tend to iucrease at an early stage of the marching but in the terminal stage they tend to return to the normal values.<br>3. In the group of munition carriers whose work is successive from day to day and is of a high degree, there can be recognized a tendency of relatively little change in the urine pH's, an increase in the donaggio value, a transient increase in the density and hourly excretion of creatinine, and also an transient increase in the quantity and hourly excretion of uric acid, revealing a tendency to become orientated to the daily successive labor.

著者

吉本 弘満

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.72, no.1, pp.359-380, 1959-12-30

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The author performed quantitative analyses of the amount of urine excreted, the urine density, pH's, microprotine content, urine protein content, the amount of Donaggio reaction-positive substance, urine creatinine, uric acid, urine lactic acid, urine phosphoric acid, and the urine calcium content in the urine before and after work, selected from various groups of persons such as a group of marathon runners, a group of soldiers marching, and a group of ammunition carriers; and obtained the following results. 1. In the group of marathon runners whose work is thought to be relatively intense and of a comparatively short duration there can be recognized a rapid decrease in the urine content, an increase in the amount of urine microprotein and in urine protein-positive cases, an increase in the hourly excretion of Donaggio reaction-positive substance, a rapid increase in the density and hourly excretion of lactic acid, a slight decrease in the density and the hourly excretion of creatinine, an increase in the density and hourly excretion of phosphoric acid, and a decrease in the density and hourly excretion of calcium. Judging these estimated values stoistically, it has become possible to obtain significant values in the Donaggio reaction and in the lactive acid with an error of less than one per cent in the hourly excretion contents and similarly significant values in the mucoprotein and phosphoric acid contents under 5 per cent deviation. 2. In the marching which is relatively of an intermediate degree of fatigue and of a longer duration, there can be observed a decrease in the quantity of urine, an incrase in the urine density, acidification of the pH, increase in the protein-positive cases; a transient increase and decrease in the excreation of creatinine and the hourly excretion amount, stability of the density and houly excretion of uric acid, a transient increase in the early stage uric acid, and a transient increase in the density and excretion of phosphoric acid. Namely, the substance estimated in this group tend to iucrease at an early stage of the marching but in the terminal stage they tend to return to the normal values. 3. In the group of munition carriers whose work is successive from day to day and is of a high degree, there can be recognized a tendency of relatively little change in the urine pH's, an increase in the donaggio value, a transient increase in the density and hourly excretion of creatinine, and also an transient increase in the quantity and hourly excretion of uric acid, revealing a tendency to become orientated to the daily successive labor.

著者

猪田 宏美 北村 佳久 千堂 年昭

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.127, no.1, pp.59-61, 2015-04-01 (Released:2015-05-01)

参考文献数

7

著者

大塚 愛二

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.133, no.2, pp.104-108, 2021-08-02 (Released:2021-09-01)

参考文献数

8

著者

青野 要 山本 道夫 飯田 荘介 内海 耕慥

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.90, no.9, pp.1297-1308, 1978

被引用文献数

1

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In relation to the mechanism by which hemolysis was induced in radiated human erythrocytes <i>in vitro</i>, several inducements of membrane lipid peroxidation and protective effects of V. E and SOD were investigated. Results obtained were as follows:<br>(1) K⁺-release from erythrocytes was accelerated by radiation prior to hemolysis. These accelerated hemolysis and K⁺-release were protected remarkably by V. E and evidently by SOD.<br>(2) Mitochondrial Fe²⁺ induced and Fe³⁺-O₂ generating system - ADP induced lipid peroxidation, and microsomal O₂ generating system - induced lipid peroxidation were also protected by V. E and SOD.<br>(3) Radiation of X-ray or ⁶⁰Co &gamma;-ray accelerated lipid peroxidation of liver homogenate, microsome and liposome. Some of these accelerated lipid peroxidations were protected effectively by V. E and SOD.<br>These results suggest that O₂ and/or OH&middot;generation by radiation induces of membrane lipid peroxidation, which leads deterioration of membrane resulting in the change of ion permeability and then hemolysis.

著者

神田 三郎

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.68, no.11, pp.1999-2006, 1956-11-30

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In the previous paper, the author reported that the cytoplasmic basophilia appears fibrous or granular by the dehydrating mechanism or by the action of RNA-precpitating agents. The purpose of this paper is to investigate the relation of minerals to cytoplasmic basophilia by means of microincineration, and also to distinguish clearly each minerals from others by alizallin or ferrocyan kalium stain after the coating with egg-white. In the nerve cells and the egg cells of pinctada maltensii treated by agglutinating agents of basophilia, mineral ash appeared showing the similar picture like as Nissl-body or giving fibrous mesh work, while on the cytoplasm which basophilia was not agglutinated, careful fixation with formalin or freezing drying, mineral ash appeared homogenous on cytoplasm. The mass of mineral ash which appeared in cytoplasm seemed to be in proportion to the quantity of nucleic acid, i. e. a quantity of mineral ash was recognized in the cytoplasm that showed strong basophilicity, and in the cytoplasm that showed weak basophilicity a small quantity of meneral ash was detected. From these observations, it was concluded that mineral ash detected in cytoplasm must be a component of basophilic organella but not of enkylema. Alizallin staining of the ash proved that mineral ash was mainly composed of calcium or magnecium. Treating with acid ferrocian kalium, however, a small amount, of iron was detected in ash too, i. g. liver cells, nucleus of granular cells in cerebellum, red cells, capsuls of liver or kidney, basement membrane and Bowman's capsule stained blue slightly by ferrocyan kalium.