文献一覧: 北一郎 (著者)

4 0 0 0 OA うつ・不安にかかわる脳内神経活動と運動による抗うつ・抗不安効果

著者: 北一郎大塚友実西島壮
出版者: Japanese Society of Sport Psychology
雑誌: スポーツ心理学研究 (ISSN:03887014)
巻号頁・発行日: vol.37, no.2, pp.133-140, 2010 (Released:2010-10-08)
参考文献数: 47
被引用文献数: 4 2

It has been suggested that regular physical exercise is beneficial to not only physiological adaptation, but also psychological health through stress reduction, antidepressant / anxiolytic properties and improvement in mood. However, since exercise regimens have varied widely across experiments, the optimal form, intensity and duration of exertion for producing the maximal benefits of exercise have yet to be established. Recent neuroscience studies have shown that physical exercise could have a positive impact on the brain, raising the hypothesis that the beneficial effects of physical exercise on psychological health are due to morphological and functional adaptation in the brain, rather than physiological adaptation to physical exercise. For example, it has been shown that physical exercise results in increased neurogenesis or expression of brain-derived neurotrophic factor as well as improved cognitive abilities or reduced stress-induced depressive behavior. Although evidence of the neural and behavioral benefits of physical exercise is accumulating, the influences of different regimens of physical exercise on the brain and behavior remain unclear. This issue aims to outline the effects of physical exercise on pathological conditions with a focus on mood disorders, including depression and anxiety, and consider the neural mechanisms of the antidepressant / anxiolytic effects of physical exercise.

2023-01-13 11:25:08
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3 0 0 0 OA 脳内低酸素とあくび反応

著者: 北一郎有田秀穂
出版者: 日本比較生理生化学会
雑誌: 比較生理生化学 (ISSN:09163786)
巻号頁・発行日: vol.18, no.2, pp.96-101, 2001-08-31 (Released:2011-03-14)
参考文献数: 42

2022-03-24 14:36:24
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2 0 0 0 OA 運動による抗うつ・抗不安作用の神経機序の解明

著者: 北一郎西島壮
出版者: 首都大学東京
雑誌: 基盤研究(C)
巻号頁・発行日: 2013-04-01

運動は脳の機能構造的変化を引き起こし、うつ病や不安障害などのストレス関連精神疾患の発症予防に貢献することが示唆されている。しかし、その脳内神経機構や有効な運動条件については依然として解明されていない。本研究では、運動の抗うつ・抗不安作用、関連脳部位に及ぼす影響及び有効な運動条件について明らかにしようとした。本研究の結果から、運動による抗うつ・抗不安作用の神経機序として、セロトニン神経系の活性化、HPA軸(CRF神経)活性の正常化、海馬神経新生の増加が考えられ、これらの脳神経系は適切な運動条件を設定することで、より効果的に変化し、抗うつ・抗不安作用をもたらすことが示唆された。