2 0 0 0 OA 気圧と虫垂炎

著者
福田 稔 安保 徹
出版者
一般社団法人 日本温泉気候物理医学会
雑誌
日本温泉気候物理医学会雑誌 (ISSN:00290343)
巻号頁・発行日
vol.59, no.4, pp.236-242, 1996 (Released:2010-04-30)
参考文献数
13

Since the incidence of acute appendicitis seems to vary depending on weather (e. g., the perforation increases under a high atmospheric pressure), we investigated the underlying mechanism.We classified 112 patients who underwent appendectomy into three groups according to the atmospheric pressure at the time of onset. We found that gangrenous cases (high infiltration of granulocytes) occur more frequently at high atmospheric pressures while catarrhal cases (no infiltration of granulocytes) occurred more frequently at low atmospheric pressures. The physiological variations of granuocytes and lymphocytes in the blood with respect to the atmospheric pressure were then examined in a healthy volunteer. Granulocytosis increases under a high pressure due to the sympathetic activity, whereas lymphocytosis increases under a low pressure due to the parasympathetic activity. Results obtained from gangrenous cases showed much granulocytosis in the blood as well as appendix while catarrhal cases showed much lymphocytosis in the blood and appendix. This seems to imply that granulocytosis induced by the increase in sympathetics activity might be closely related to the onset of gangrenous appendicitis. Even in gangrenous cases, bacteria were not found around the granulocytes in the appendix or in the cytoplasma of granulocytes as observed in electron microscopy. These results may be extremely useful in exploring the etiology of suppurative diseases which are caused without apparent bacterial infections.
著者
安保 徹
出版者
新潟大学
雑誌
新潟医学会雑誌 (ISSN:00290440)
巻号頁・発行日
vol.117, no.3, pp.114-119, 2003-03

We could not properly understand the mechanisms underlying gastroentestinal failure without introduction of the concept of "Regulation of leukocytes by the autonomic nervous system". leukocyles consiste of granulocytes and lymphocytes and they are regulated by the sympathetic nervous system and the parasympathetic nervous system, respectively. Therefore, the number of granulocytes increases by stimulation of sympathetic nerves whereas that of lymphocytes increases by stimulation of parasyrnpathetic nerves. Almost all of these responses are beneficial for our body protection. However, If the autonomic nervous system deviates too much to one direction, our body falls victim to certain diseases, including gastroentestinal failure.