著者

石川 かおり 葛谷 玲子

出版者

岐阜県立看護大学

雑誌

岐阜県立看護大学紀要 (ISSN:13462520)

巻号頁・発行日

vol.12, no.1, pp.85-92, 2011-03

著者

富谷 玲子 内海 由美子 斉藤 祐美 トミヤ レイコ ウツミ ユミコ サイトウ ユミ TOMIYA Reiko UTSUMI Yumiko SAITO Yumi

出版者

東京外国語大学多言語・多文化教育研究センター

雑誌

多言語多文化-実践と研究 (ISSN:18825664)

巻号頁・発行日

vol.2, pp.116-137, 2009-12

著者

富谷 玲子 Tomiya Reiko

出版者

神奈川大学

雑誌

神奈川大学言語研究 (ISSN:09153136)

巻号頁・発行日

no.32, pp.59-78, 2009

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Foreign residents in Japan called "newcomers" have been increasing since the late 1970s. Japanese language support for newcomers was started by citizen volunteers around the mid 1980s, and these "community language classes" now exist nationwide. Nowadays Japanese language support for newcomers is called "Japanese language education in community" and has come to be focused on as one area of investigation in Japanese language teaching research. This paper aims to review Japanese language education in community from a critical point of view. First, the ignificance and limitations of citizen volunteers who have been contributing Japanese language education in community are discussed. Second, problems related to constituent member(Japanese and newcomers)in community classrooms from the viewpoint ofnewcomers are presented. Finally, the reasons why there has been little or no discussion incorporating newcomers themselvesas a concerned-party are analyzed. In order for newcomers to be able to fully participate in the society, it is indispensable to guarantee the community language, that is, to guarantee opportunities to learn the Japanese language. This paper points out the necessity to establish a system to provide opportunities to newcomers. It also points out the necessity for both Japanese people and newcomers themselves to question the significance of Japanese language learning.

著者

富谷 玲子 Tomiya Reiko

出版者

神奈川大学

雑誌

神奈川大学言語研究 (ISSN:09153136)

巻号頁・発行日

vol.32, pp.59-78, 2010-03-10

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Foreign residents in Japan called “newcomers” have been increasing since the late 1970s. Japanese language support for newcomers was started by citizen volunteers around the mid 1980s, and these “community language classes” now exist nationwide. Nowadays Japanese language support for newcomers is called “Japanese language education in community” and has come to be focused on as one area of investigation in Japanese language teaching research. This paper aims to review Japanese language education in community from a critical point of view. First, the ignificance and limitations of citizen volunteers who have been contributing Japanese language education in community are discussed. Second, problems related to constituent member(Japanese and newcomers)in community classrooms from the viewpoint ofnewcomers are presented. Finally, the reasons why there has been little or no discussion incorporating newcomers themselvesas a concerned-party are analyzed. In order for newcomers to be able to fully participate in the society, it is indispensable to guarantee the community language, that is, to guarantee opportunities to learn the Japanese language. This paper points out the necessity to establish a system to provide opportunities to newcomers. It also points out the necessity for both Japanese people and newcomers themselves to question the significance of Japanese language learning.

著者

井上 芳光 山瀧 夕紀 谷 玲子

出版者

日本生理人類学会

雑誌

日本生理人類学会誌 (ISSN:13423215)

巻号頁・発行日

vol.11, no.1, pp.1-6, 2006

参考文献数

15

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本研究では,母親の運動経験や活動性が幼児の運動量や運動能力に及ぼす影響を検討するため,健康な2〜4歳児男女75名に対して日常生活下の歩行量と3種目の運動能力テスト(テニスボール投げ・20m走・立ち幅跳び),彼らの母親に対して日常生活下の歩行量および運動歴・運動スポーツに対する価値観などを問うアンケート調査をそれぞれ実施した.アンケート結果と母親の日常歩行量の関係において,母親の運動経験年数が多い者が少ない者より日常歩行量が有意に多かった.アンケートで母親が『活動的である』および『外に出かけることが好き』と回答した2・3歳児の日常歩行量は,母親が『活動的でない』および『家の中で過ごすことが好きだ』と回答した2・3歳児の歩行量より有意に多かった.なお,この関係は4歳児ではみられなかった.日常生活下の歩行量において,母親と子どもとの間に有意な正の相関関係が2・3歳児でも4歳児でも認められた.走・投・跳に関する子どもの運動能力テストと子どもの日常歩行量の関連性において,2・3歳児では,ボール投げvs.歩行量に有意な相関が認められなかったものの,20m走や立ち幅跳びは歩行量と有意な相関関係を有した.4歳児では20m走や立ち幅跳びとともに,ボール投げでも歩行量と有意な相関傾向がみられた.以上の結果,母親の運動歴が母親自身の日常歩行量に影響し,それと母親の活動性が子どもの歩行量に反映し,ひいては子どもの運動能力にも影響する可能性が示唆された.

著者

白 云哲 奥村 敏 常松 尚志 焦 其彬 小野 伸二 鈴木 さやか 黒谷 玲子 佐藤 元彦 南沢 享 石川 義弘

出版者

日本生理学会

雑誌

日本生理学会大会発表要旨集

巻号頁・発行日

vol.2008, pp.180-180, 2008

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Objective: Autonomic nervous activity is altered under microgravity. Cardiac response to autonomic regulation is mostly determined by &beta;-adrenergic receptors/cAMP signal that is regulated by adenylyl cyclase (AC). We thus examined the role of a major cardiac AC isoform, type 5 AC (AC5), in the autonomic regulation of the heart under microgravity induced by parabolic flights. Methods: We used transgenic mice with either disrupted (AC5KO) or overexpressed AC5 in the heart (AC5TG), and analyzed heart rate variability during parabolic flight. Results: The standard deviation of normal R-R intervals, a marker of total autonomic variability, was significantly greater under microgravity in AC5KO while no significant changes in WT and AC5TG. LF (low frequency)/HF (high frequency), a marker of sympathetic activity, became significantly lower under microgravity in WT and AC5TG while there was no such a decrease in AC5KO. Normalized HF, a marker of parasympathetic activity, became significantly greater in WT under microgravity, and became even greater in AC5TG, while no such increase in AC5KO. Conclusions: Putting together, changes in autonomic indexes in response to microgravity were augmented in AC5TG while attenuated in AC5KO, suggesting that AC5 plays a major role in determining the magnitude of cardiac responses to autonomic regulation under microgravity. <b>[J Physiol Sci. 2008;58 Suppl:S180]</b>

著者

福井 美園 滝谷 玲子 多田 敬三

出版者

慶應義塾大学

雑誌

共立薬科大学研究年報 (ISSN:04529731)

巻号頁・発行日

no.25, pp.p49-59, 1981-03

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The decomposition of 1-nitroso-1-butyl-3,3-dimethylurea (DM-NBU), which was found to have both leukomogenic and vaginatumorigenic activities on female rats, was studied in the buffer solutions of various pH values from 2 to 12 at 37℃. It was found that the decomposition velocity of DM-NBU was lowest in the neutral medium and increased as pH values either increased or decreased from 7,and the velocity was generally much lower than that of 1-nitroso-1-butylurea (NBU). The effect of the concentration of DM-NBU on the velocity has not yet been examined in detail, but it has been found that lower concentrations resulted in more rapid decomposition than higher ones did in the range of pH examined only except at pH 10. The main decomposition products of DM-NBU were carbondioxide, dimethylamine, 1-butanol and 2-butanol. Although the above two isomers of butanol were also detected and determined in the case of NBU and their total amounts were almost equal at each pH values of 2,7 and 12,in the case of DM-NBU, they were almost equal in the range of pH values from 12 to 6 but they fell suddenly at pH 5 and, thereafter, gradually decreased as pH values decreased. The ratio of the amount of 1-butanol to that of 2-butanol was 1.8-2 in the range of pH tested. The determination of the residual amounts of DM-NBU was made absorption-spectrophotometrically and that of the butanols was carried out gaschromatographically after the decomposition proceeded completely.

著者

鈴木 厚子 福井 美園 中安 寿美子 滝谷 玲子 多田 敬三

出版者

慶應義塾大学

雑誌

共立薬科大学研究年報 (ISSN:04529731)

巻号頁・発行日

vol.28, pp.1-15, 1984-03-25

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The reaction of N-nitroso-N-butylurea (NBU) with an equivalent of L-α-aminoacid was made in the buffer solution of pH 7.2 at 37℃ for 3 weeks. α-Carbamoyl-aminoacid was isolated and identified for each α-aminoacid examined together with the decomposition-products of NBU such as 1-and 2-butanols, urea and a slight amount of butylurea. A quantitative research was also carried out for L-methionine and L-leucine by high performance liquidchromatography. It was found that about 60% of L-methionine and 53% of L-leucine was carbamoylated respectively with an equivalent of NBU during 5 days, but, thereafter, no appreciable further carbamoylation was observed, and also that 83% of methionine reacted with twice equivalent of NBU. The velocity and products of decomposition of NBU in the buffer solutions of various pH were reinvestigated. The minimum rate constant for the apparent first-order decomposition was found in the region of pH3. The determination of butanols produced by gaschromatography of ether extracts from the reaction mixture showed that not only their total amounts were practically unvaried but also the ratio of 1-butanol to 2-butanol was almost equal value of 2.0 in various pH regions. The amount of urea or butylurea produced in each pH solution was relatively estimated by semiquantitative thin-layer chromatography. In the case of urea, no appreciable difference was observed except in the regions of pH3 and pH4,where urea was found to be a minor product and, instead, an unknown product was detected, whereas the formation of butylurea was slight in higher pH regions than pH5,however, in more acidic medium denitrosation seemed to be considerable although it might be a side reaction in the whole decomposition-pathway. Some considerations and discussions were made on the mechanism of decomposition of NBU, and also on the results from the quantitative study for the reaction of NBU with α-aminoacids.

著者

渡邉 剛広 島 麗香 坂原 聖士 高倉 啓 黒谷 玲子 阿部 宏之

出版者

日本繁殖生物学会

雑誌

日本繁殖生物学会 講演要旨集 第106回日本繁殖生物学会大会

巻号頁・発行日

pp.OR1-15, 2013 (Released:2013-09-10)

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【目的】ミトコンドリア内膜に存在する呼吸鎖複合体IV(シトクロムcオキシダーゼ:COX)は電子伝達系の終末酵素である。COXは機能分化した体細胞において詳しい機能解析は行われているが,卵子や初期胚における研究はほとんど進んでいない。本研究では,マウスの初期発生におけるCOXの役割を調べるために,未受精卵子から器官形成期までの初期発生におけるCOX mRNA発現とミトコンドリア呼吸機能を解析した。【方法】ICR系雌マウスからMII期卵母細胞,1細胞期〜8細胞期胚,桑実胚,胚盤胞および胎生8.5日胚(E8.5)を回収した。各発生ステージにおいて,COXを構成する全13サブユニットのmRNAをRT-PCRにより解析した。また,卵母細胞および胚において(1)酸素消費量,(2)活性型ミトコンドリアの局在と相対膜電位,(3)ATP含量を解析した。【結果】ミトコンドリアゲノム由来のCOX1,COX2およびCOX3のmRNAは,全ての発生ステージの卵母細胞および胚において検出された。一方,核ゲノム由来COXの mRNAは,MII期の卵母細胞ではCOX6a,COX7bおよびCOX7cを除く7サブユニットのmRNAが検出されたが,1細胞期から8細胞期の胚においてこれら7サブユニットのmRNAは著しく発現量が低下した。桑実胚および胚盤胞ではCOX7cを除く9サブユニットのmRNAが検出され,E8.5では核ゲノムにコードされる全サブユニットのmRNAが検出された。この核ゲノムCOX mRNAの増加は,酸素消費量の増加とミトコンドリア膜電位活性の上昇と一致した。本研究では,未受精卵子から器官形成期胚に至るマウス初期発生におけるCOX mRNAの発現パターンの解析に初めて成功した。ミトコンドリアゲノムと核ゲノムのCOX mRNAはそれぞれ異なる発現パターンを示し,ミトコンドリア呼吸機能の亢進に核ゲノムCOXサブユニットが重要な役割を果たしていることが示唆された。