著者
上野 明 松崎 悦子 百木 克夫 斉藤 伍作 酒井 純雄
出版者
The Japanese Society for Medical Mycology
雑誌
真菌と真菌症 (ISSN:05830516)
巻号頁・発行日
vol.6, no.2, pp.109-114, 1965-06-20 (Released:2009-12-18)
参考文献数
4
被引用文献数
1 1

11-jodo-10-undecynoic acid (K-4172) was synthesised in our laboratory from 10-undecynoic acid reacting with iodine in presence of alkaline hydroxide. Fungistatic and bacteriostatic activities of K-4172 were examined. It showed significant antifungal activities, especially against Trichophytons and Crytococcus neoformans, but it had weak antibacterial activities.In in vivo test by experimental trichophytosis on guineapigs, it showed also significant therapeutic activities at the concentration of 0.5% in alcohol solution. It is very interest that in the in vivo test 0.5% tincture of K-4172 was more effective when it was applied in combination with 10% of 2, 4, 6-tribromophenyl caproate.Interperitoneal and oral LD50 of K-4172 dissolved in olive oil were 132 and 225mg/Kg respectively and intraperitoneal LD50 of its sodium salt was 134mg/Kg. Chronic toxicity test of K-4172 on mice and rat showed both almost no side effect when it was admidistrated intraperitoneally and orally. The authers persume from these data that K-4172 is safely available for treatment of human trichophytosis.
著者
佐藤 克明 坂 勉 酒井 純 高木 善昭
出版者
一般社団法人 粉体粉末冶金協会
雑誌
粉体および粉末冶金 (ISSN:05328799)
巻号頁・発行日
vol.43, no.11, pp.1328-1332, 1996-11-15
参考文献数
1

The pulleys are used to be produced by powder metal due to cost performance and high productivity. Recently, the timing belt pulleys for automotive engine are required extra high functions which have sensor or light weight, and the complex shape pulleys are tend to increase. This report introduces the examples of the design and engineering of these pulleys as follows.<BR>1)The light weight pulleys with thin wall curtain shape rim are lighter than stamping pulleys.<BR>2)The cam shaft pulleys with sensing cam are manufactured as utilizing powder flow during compacting.<BR>3)The crank shaft pulleys with sensing cam at flange portion for miss fire detection have high accuracy of angle phase between key way and sensing cam.
著者
中條 直樹 佐藤 昭裕 神山 孝夫 岡本 崇男 酒井 純 塚原 信行 山口 巌 山田 勇 今村 栄一 水野 晶子 田中 大
出版者
名古屋大学
雑誌
基盤研究(B)
巻号頁・発行日
2008

2008年度には、本プロジェクトにおいて正本と位置づけた『ラヴレンチー版原初年代記』のコンコーダンス(CD)を作成し、2009年度には、その異本の一つである『ラジヴィル年代記』のコンコーダンス(CD)を作成した。最終年度においては前年度に電子化を終えていた『トロイツァ年代記』について徹底した校正を行い、そのコンコーダンスを作成し、これら三つの年代記のコンコーダンスを一枚のCDに収めることにより、共通する語の文脈等の環境の差異の検証を飛躍的に容易に可能にした。