著者
Yoshiyuki Sugishita Takuya Yamagishi Yuzo Arima Narumi Hori Naomi Seki
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
pp.JJID.2015.312, (Released:2015-09-11)
参考文献数
10
被引用文献数
1 9

The number of notified syphilis cases in Tokyo has more than doubled in recent years. The number of reported primary and secondary syphilis cases increased from 108 cases (0.8 per 100,000 population) in 2007 to 245 cases in 2013 (1.9 per 100,000 population). During this period, the majority of cases was male (905/1,024), and the recent increase among primary and secondary syphilis cases was attributed to the increase among males (90/108 [83%] cases in 2007 to 218/245 [89%] cases in 2013); men aged 20-49 years contributed most to the increase, with those aged 30-34 years having the highest rate in 2013. Male-to-male transmission was the primary route of infection reported, and men who have sex with men (MSM) accounted for nearly 80% of male cases in 2013. Syphilis appears to be reemerging in Tokyo, and reducing the risk of acquiring syphilis among MSM aged 20-49 years should be a public health priority in Tokyo.
著者
Panita Pathipvanich Naho Tsuchiya Archawin Rojanawiwat Wolf-Peter Schmidt Wattana Auwanit Pathom Sawanpanyalert Koya Ariyoshi
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.66, no.5, pp.375-378, 2013 (Released:2013-09-19)
参考文献数
14
被引用文献数
3 5

We conducted a hospital-based descriptive study to describe the changing pattern of patient numbers, characteristics, and mortality rates among human immunodeficiency virus (HIV)-infected patients in northern Thailand over 15 years. The survival status on October 31, 2010 of all HIV-infected adults who attended an HIV center in a government hospital between 1995 and 2010 was ascertained. In total, 3,706 patients were registered, 2,118 (57.2%) of which were male. The survival status of 3,439 patients (92.9%) was available. In addition, 1,543 deaths were identified out of 12,858 person-year-observations (PYO) resulting in a mortality rate of 12.4 deaths/100 PYO (95% confidence interval [CI], 11.3–13.0). An initial decline in mortality rates was observed prior to 1999, probably because of an increase in the proportion of less symptomatic patients. After the introduction of the national highly active antiretroviral therapy (HAART) program, a profound decline in mortality rates was observed, reaching 2.0 deaths/100 PYO (95% CI, 1.4–2.9) in 2010. Simultaneously, the number of patients on follow-up increased by nearly fourfold. Although HAART has drastically improved the survival of HIV-infected patients, the number of patients receiving therapy at this HIV clinic has substantially increased. While referral of HIV patients to general physicians' care should be urged, we cannot overemphasize the importance of preventing new HIV infections.
著者
Syada Monira Hoque Md Akram Hossain Shyamal Kumar Paul Md Chand Mahmud Salma Ahmed Nasir Uddin Mahmud Emily Rahman Khan Md Annaz Mus Sakib Souvik Ghosh Nobumichi Kobayashi
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.66, no.3, pp.256-259, 2013 (Released:2013-05-23)
参考文献数
22
被引用文献数
2

To investigate the accurate prevalence of genital Chlamydia trachomatis infection in Mymensingh, a local area in central-northern Bangladesh, 40 female sex workers (FSW) and 110 sexually active women (SAW, non-FSW) of reproductive age from a local community with clinical symptoms were examined by an immunochromatography test (ICT) and plasmid-based polymerase chain reaction (PCR) during a 1-year period from July 2011 to June 2012 using the endocervical swab as a specimen. By ICT and/or PCR, the C. trachomatis detection rate was 58% and 27% in FSW and SAW, respectively, showing a significant difference (P < 0.01). Two C. trachomatis strains from FSW were determined to be serovar D by ompA-based PCR and sequencing analysis. The highest prevalence was found among women aged 15 to 35 years. A lower socioeconomic status was considered to be an important risk factor for C. trachomatis infection in FSW but not in SAW. This is the first study to determine the prevalence of C. trachomatis infections in FSW and SAW in the same local area in Bangladesh.
著者
Koichiro Suemori Yumi Taniguchi Ai Okamoto Akiko Murakami Fumihiro Ochi Harutaka Aono Naohito Hato Haruhiko Osawa Hitoshi Miyamoto Takashi Sugiyama Masakatsu Yamashita Hisamichi Tauchi Katsuto Takenaka
出版者
National Institute of Infectious Diseases
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.75, no.5, pp.523-526, 2022-09-30 (Released:2022-09-22)
参考文献数
16
被引用文献数
2

We conducted two-year seroprevalence surveys of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies among outpatients and healthcare workers (HCWs) at Ehime University Hospital. Data were collected for outpatients and HCWs in June 2020 (1st survey), December 2020 (2nd survey), July 2021 (3rd survey), and December 2021 (4th survey), focusing on demographics, occupation, and the seroprevalence of anti-SARS-CoV-2 antibodies. Blood samples were obtained from randomly selected outpatients who visited our hospital for medical care and HCWs undergoing regular medical checks with opt-out informed consent. SARS-CoV-2 antibody positivity was evaluated using two laboratory-based quantitative tests. The total number of participants enrolled was 6,369 (1st survey: 1,000 outpatients and 743 HCWs, 2nd survey: 1,000 outpatients and 407 HCWs, 3rd survey: 1,000 outpatients and 804 HCWs, 4th survey: 1,000 outpatients and 415 HCWs). The prevalence of SARS-CoV-2 antibodies among outpatients and HCWs was 0–0.1% and 0–0.124% during the research period, respectively, and changed little over time. These findings suggest that the magnitude of COVID-19 infection during the pandemic among outpatients and HCWs in this rural hospital might have been small.
著者
Ya-Ping Li Jie-Wen Cai Li-Juan Liao Han Ding Xun-Jie Cao Guo-Dong Zhu Xu-Guang Guo
出版者
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
pp.JJID.2021.406, (Released:2021-11-30)
参考文献数
21
被引用文献数
4

Based on previous studies, we found that Bacillus Calmette–Guérin(BCG) vaccination may have a role in preventing SARS-CoV-2 infection. Thus, we conducted this meta-analysis to investigate this protective effect. We searched in Embase, PubMed, Web of Science, Cochrane Library, BioRxiv, and MedRxiv databases for studies that evaluated the relationship between BCG vaccination and SARS-CoV-2 infection or COVID-19 disease. The quality of all included studies was assessed through the Risk of Bias in Non-randomized Studies - of Interventions and the Agency for Healthcare Research and Quality. Review Manager (Version 5.3) was used for conducting all data analyses. A total of 8 studies were ultimately included in our meta-analysis. Our primary analysis found significantly lower SARS-CoV-2 infection rate in the BCG vaccination group compared to the control group, with a odds ratio (OR) of 0.61, (95% confidence interval (CI) 0.39 to 0.95, P = 0.03; I2 = 31%, and P = 0.21 for heterogeneity). Our study indicated that BCG vaccination can protect against SARS-CoV-2 infection. However, there is insufficient evidence that BCG vaccination can reduce the severity of COVID-19.
著者
Yohei Matoba Chieko Abiko Tatsuya Ikeda Yoko Aoki Yu Suzuki Kazue Yahagi Yoko Matsuzaki Tsutomu Itagaki Fumio Katsushima Yuriko Katsushima Katsumi Mizuta
出版者
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.68, no.2, pp.138-141, 2015 (Released:2015-03-23)
参考文献数
24
被引用文献数
40 74

The available literature on human coronaviruses (HCoVs) in Japan is limited to epidemiological studies conducted over a maximum of 1 year. We conducted a 4-year study of HCoVs by analyzing 4,342 respiratory specimens obtained in Yamagata, Japan, between January 2010 and December 2013. A pan-coronavirus reverse transcription-PCR screening assay was performed, and all HCoV-positive specimens were subsequently confirmed by sequencing of the PCR products. We detected in 332 (7.6%) HCoV strains during the study period, comprising 133 (3.1%) HCoV-NL63, 83 (1.9%) HCoV-HKU1, 78 (1.8%) HCoV-OC43, and 38 (0.9%) HCoV-229E strains. HCoV detection per year ranged from 3.5% to 9.7%. HCoVs were detected mainly in winter, with January (28.5%) and February (25.3%) 2011 and December 2012 (14.6%) being the only months in which HCoV-NL63 detection per month exceeded 10.0%. HCoV-HKU1 displayed clear biennial peaks in January (18.3%) and February (10.7%) 2010 and in February (18.8%) and March (14.7%) 2012. The peak detection of HCoV-OC43 was 13.6% in November 2010, while that of HCoV-229E was 10.8% in March 2013. Our results indicated that there may be annual variations in the circulation of individual HCoV strains. Further long-term surveillance is necessary to clarify HCoV prevalence and circulation patterns in Japan.
著者
Masahiro Ishikane Yusuke Miyazato Satoshi Kustuna Tetsuya Suzuki Satoshi Ide Keiji Nakamura Shinichiro Morioka Harutaka Katano Tadaki Suzuki Norio Ohmagari
出版者
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
pp.JJID.2020.240, (Released:2020-05-29)
参考文献数
14
被引用文献数
1

We report a case of patient in Japan with Coronavirus disease 2019 (COVID-19) with false-negative of reverse transcription polymerase chain reaction for Severe Acute Respiratory Syndrome Coronavirus 2 of pharyngeal swab, from a Chinese traveller returning from Wuhan, Hubei Province, China. If a patient is clinically or epidemiologically suspected of COVID-19, appropriate infection and prevention control measures such as standard, contact, and droplet precaution are needed until the patient is proven to be true-negative.
著者
Mugen Ujiie Shinya Tsuzuki Michiyo Suzuki Masayuki Ota Tetsuya Suzuki Hidetoshi Nomoto Kei Yamamoto Sho Saito Akatsuki Kokaze Noriko Kinoshita
出版者
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.74, no.5, pp.399-404, 2021-09-30 (Released:2021-09-22)
参考文献数
18
被引用文献数
6

Tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine is generally used for booster vaccination of infants in Europe and the United States to avoid increased reactogenicity after diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccination. However, Japan has extended the use of additional DTaP vaccination without reducing the antigen dose for diphtheria and pertussis in adolescents and adults, despite limited reports on its safety in adults. This prospective, observational, questionnaire-based study investigated the occurrence of adverse events (AEs) following DTaP vaccination between June 2018 and June 2019 in participants aged 10 years or older. Of the 250 eligible participants, 235 (94%) responded regarding AEs. Among them, 133 (56.6%) reported AEs, of which 39 reported systemic AEs (16.6%) and 120 reported local AEs (51.1%) attributed to DTaP vaccination. The incidence of local AEs was markedly higher with DTaP vaccination than with non-DTaP vaccination (51.1% vs. 10.5%), and AEs appeared later (P < 0.01) and lasted longer (P < 0.01) with DTaP vaccination. However, more than 75% of these AEs resolved within 7 days. DTaP vaccination was not associated with any serious AEs. These results indicate that the DTaP vaccine can be widely used as a booster in adults as an alternative to the Tdap vaccine.
著者
Mugen Ujiie Shinya Tsuzuki Michiyo Suzuki Masayuki Ota Tetsuya Suzuki Hidetoshi Nomoto Kei Yamamoto Sho Saito Akatsuki Kokaze Noriko Kinoshita
出版者
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
pp.JJID.2020.947, (Released:2021-01-29)
参考文献数
18
被引用文献数
6

Tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine is generally used for booster vaccination in Europe and the United States to avoid increased reactogenicity after diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccination in infants. However, Japan has extended the use of additional DTaP vaccination without reducing the antigen dose for diphtheria and pertussis to adolescents and adults despite limited reports on its safety in adults. This prospective observational questionnaire-based study investigated the occurrence of adverse events (AEs) following DTaP vaccination between June 2018 and June 2019 in participants aged 10 years or older. Of 250 eligible participants, 235 (94%) responded regarding AEs. Of these 235 participants, 133 (56.6%) reported AEs, with 39 reporting systemic AEs (16.6%) and 120 reporting local AEs (51.1%) attributed to DTaP vaccination. The incidence of local AEs was much higher with DTaP than with non-DTaP vaccinations (51.1% vs. 10.2%), and the AEs appeared later (p<0.01) and lasted longer (p<0.01) with DTaP vaccination. However, more than 75% of these AEs resolved within 7 days. DTaP vaccination was not associated with any serious AEs. These results indicate that the DTaP vaccine can be widely used as a booster in adults as an alternative to the Tdap vaccine.
著者
Hidemasa Nakaminami Hinako Kawasaki Shunsuke Takadama Hiroshi Kaneko Yoshiko Suzuki Hiroshi Maruyama Norihisa Noguchi
出版者
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.74, no.1, pp.82-84, 2021-01-29 (Released:2021-01-22)
参考文献数
15
被引用文献数
8

In the last decade, methicillin-resistant Staphylococcus aureus (MRSA) has been identified in livestock animals, such as swine, poultry, and veal calves, and has been termed livestock-associated MRSA (LA-MRSA). LA-MRSA sequence type (ST) 398 strains can effectively infect and colonize humans, with subsequent human-to-human transmission in both community and hospital settings. Unlike other countries, LA-MRSA had not been reported in Japanese patients until 2019. However, we recently reported a case of intractable arthritis caused by an LA-MRSA CC398 (ST1232) clone, which is a single-locus variant of ST398, in a patient in Tokyo, Japan, with no animal contact (Nakaminami H, et al. Emerg Infect Dis. 2020; 26: 795-7.). Uniquely, the strain was positive for Panton-Valentine leukocidin. Here, we report the second such case in Japan. To prevent the dissemination of LA-MRSA in the Japanese community, the prevalence of the CC398 MRSA clone should be closely monitored in the future.
著者
Guoqing Cao Shaotao Tang Dehua Yang Wenjia Shi Xiaorong Wang Hua Wang Chen Li Jia Wei Ling Ma
出版者
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
pp.JJID.2020.165, (Released:2020-05-29)
参考文献数
22
被引用文献数
23

In December 2019, a cluster of cases of acute respiratory illness, novel coronavirusinfected pneumonia, occurred in Wuhan, Hubei Province, China. The false-negative nasopharyngeal swabs of SARS-CoV-2 caused the delayed diagnosis of COVID-19 which hindered the prevention and control of the pandemic. The transmission risk of SARS-CoV-2 in negative nasopharyngeal swabs cases were little addressed previously. This study evaluated two clusters of COVID-19 in six patients. Four of six (66.7%) showed negative RNA of SARS-CoV-2 by nasopharyngeal swabs. All epidemiological, clinical and laboratory information was collected. The first cluster was a nosocomial infection of four health care providers at early January. One of them made sequential familial cluster of infection. All patients received either selfquarantined at home or were admitted to hospital for isolated treatment. All recovered and had anti-SARS-CoV-2 IgG and/or IgM positive (100%) for serological detection of SARS-CoV-2 at recovery stage. Our study provides a cautionary warning that negative results of nasopharyngeal swabs of suspected SARS-CoV-2 infection can increase the risk of nosocomial infection among health care providers. Serologic detection for anti-SARS-CoV-2 IgG and/or IgM is an important test in the assistant diagnosis of COVID-19.
著者
Hiroshi Yoshikura Fumihiko Takeuchi
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
pp.JJID.2015.670, (Released:2016-05-09)
参考文献数
23
被引用文献数
1 1

The size distribution of the local infection cluster (LIC), a group of patients reported from the same prefecture without interruption in successive weeks, was scale-free for infections that are transmitted from person to person (e.g., measles, rubella, syphilis and HIV/AIDS). For infections that never spread from person to person, the distribution was entirely random. The size distribution for measles, rubella, syphilis and HIV/AIDS could be simulated successfully by random coin tossing with probabilities that were higher for highly populated prefectures.The size distribution of the population in the large municipalities (>120,000) as well as that of LICs were found scale free. As the number of patients per prefecture was correlated with an equation P=kNm, where m was 1.38 for syphilis, 1.63 for HIV/AIDS and 2 for measles or rubella, the frequency distribution of N1.38, N1.6 and N2, where N was population of municipalities, were compared with the frequency distributions of LIC sizes of syphilis, HIV/AIDS, measles and rubella. The frequency distribution of LICs, particularly those of measles and rubella during the large epidemic years, was close to the frequency distribution of Nm. The analysis suggested that LICs were products of stochastic events under the influence of the municipality population size.
著者
Ippei Watanabe Kentaro Yamada Akira Aso Okio Suda Takashi Matsumoto Takaaki Yahiro Kamruddin Ahmed Akira Nishizono
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.66, no.1, pp.17-21, 2013 (Released:2013-01-22)
参考文献数
23
被引用文献数
4 12

A mass rabies vaccination of dogs has been conducted annually in Japan over the last 60 years. To assess both current levels of rabies virus-neutralizing antibody (VNA) in dogs and the rationale for current vaccination procedures, we used a rapid fluorescent focus inhibition test to determine VNA levels in 756 dogs that had visited animal hospitals in Japan. We found that 51.1% of the dogs that had received 1 rabies vaccination had protective VNA levels (≥0.5 IU/ml) with a geometric mean of 0.61 IU/ml. In contrast, 97.8% of the dogs that had been vaccinated at least twice had protective VNA levels with a geometric mean of 7.86 IU/ml. Furthermore, 97.9–100% of the dogs vaccinated at least twice retained protective VNA levels into the second year after the last vaccination. Although VNA levels in the dogs vaccinated at least twice tended to decline 2 years after the last vaccination, 78.9% retained protective VNA levels. Thus, the current rabies vaccination schedule provides adequate protection, but the registration system and vaccination schedule needs to be improved to ensure that increased numbers of dogs are vaccinated against rabies.
著者
Caroline Wasonga Shingo Inoue James Kimotho Kouichi Morita Juliette Ongus Rosemary Sang Lillian Musila
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.68, no.5, pp.410-414, 2015 (Released:2015-09-18)
参考文献数
16
被引用文献数
1 6

Chikungunya (CHIK) is a mosquito-borne viral disease. In the 2004 CHIK outbreak in Kenya, diagnosis was delayed because of the lack of accurate diagnostics. Therefore, this study aimed to develop and evaluate an in-house IgM-capture enzyme linked immunosorbent assay (ELISA) (in-house ELISA) for the detection of chikungunya virus (CHIKV) infections. Anti-CHIKV antibodies were raised in rabbits, purified and conjugated to horseradish peroxidase. These anti-CHIKV antibodies and cell-culture derived antigen were used to develop the ELISA. To validate the in-house ELISA, 148 patient sera from the 2005 Comoros CHIK outbreak were tested with centers for disease control and prevention (CDC) IgM-capture ELISA (CDC ELISA) and focus reduction neutralization test (FRNT) as reference assays. The in-house ELISA had a sensitivity of 97.6% and specificity of 81.3% compared to the CDC ELISA and a sensitivity of 91.1% and specificity of 96.7% compared to FRNT. Furthermore, 254 clinically suspected dengue patient samples from Eastern Kenya, collected in 2013, were tested for CHIKV IgM using the in-house ELISA. Out of the 254 samples, 26 (10.2%) were IgM positive, and of these 26 samples, 17 were further analyzed by FRNT and 14 (82.4%) were positive. The in-house ELISA was able to diagnose CHIKV infection among suspected dengue cases in the 2013 outbreak.
著者
Yoshio Tsuda Yoshihide Maekawa Kohei Ogawa Kentaro Itokawa Osamu Komagata Toshinori Sasaki Haruhiko Isawa Takashi Tomita Kyoko Sawabe
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
pp.JJID.2014.576, (Released:2015-03-13)
参考文献数
27
被引用文献数
4 48

A total of 160 autochthonous dengue cases transmitted by Aedes albopictus were reported from August to October 2014 in Tokyo Metropolis, Japan. Ae. albopictus is a medically important vector of dengue virus which has been expanding its geographic distribution in temperate regions. The understanding of the distribution and density of biting Ae. albopictus during the dengue outbreak case in Tokyo 2014 is valuable and important to evaluate the epidemic-risk of dengue fever in other highly populated cities in Europe. Of the 160 cases, 134 patients had visited a same park located in central Tokyo, Yoyogi Park. Mosquitoes infected with dengue virus were collected from this park suggesting that the place was the exclusive center of dengue transmission. This study aimed to collect referential data to estimate the transmission threshold of dengue virus in terms of biting density of Ae. albopictus and demonstrated high transmission-risk areas of dengue virus in Yoyogi Park and the vicinity. The overall mean density of biting Ae. albopictus, 7.13/man/8 min, was sufficiently high for successful transmission of dengue virus, and areas with biting densities higher than the overall mean density were classified as high transmission-risk areas of dengue virus in Yoyogi Park.
著者
Md. Nazrul Islam Mondal Nazrul Hoque Md. Rocky Khan Chowdhury Md. Sabbir Hossain
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
pp.JJID.2013.323, (Released:2014-11-25)
参考文献数
30
被引用文献数
1 15

The Human Immunodeficiency Virus (HIV) epidemic continues to be subjected too much misconceptions and misinformed opinions which increases the risk of HIV transmission. Therefore, the aim of this study is to identify the determinant factors of different socioeconomic and demographic factors on misconceptions about HIV transmission of ever-married women in Bangladesh. Data and necessary information of 9,272 ever-married women were extracted Bangladesh Demographic and Health Survey 2011. The three types of misconceptions were considered. Both bivariate and multivariate analyses were used as the statistical tools to determine the factors of misconceptions about HIV transmission. The results revealed that misconceptions are more prevalent among the women of older aged, less educated, husband's less education, rural areas, poor economic condition, and less access to mass media. The respondent's age, education, husband's education, place of residence, wealth index, and exposure to mass media are significantly associated with the misconceptions. Finally, logistic regression analysis indentified age, education, place of residence, wealth index, and exposure to mass media are as the significant predictors. The socioeconomic factors are the key determinants of misconceptions about HIV transmission. Therefore, intervention programs should be aimed at HIV prevention through education and awareness programs to reduce misconceptions treating as the important parts of the prevention strategy.
著者
Ryo Shimada Hiroyuki Tsukagoshi Rina Kubota Daisuke Shinoda Yuri Shinohara Akio Saito Fumitaka Inoue Tadaaki Endo Nobuhiro Saruki
出版者
National Institute of Infectious Diseases
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.76, no.4, pp.263-265, 2023-07-31 (Released:2023-07-24)
参考文献数
13

Human rhinovirus (HRV) infections are generally referred to as the common cold, and are the main cause of mild symptoms. HRV is less frequently implicated in the development of severe respiratory infections. This study reports a nosocomial outbreak of bronchitis and pneumonia caused by HRV in a hospital during the COVID-19 epidemic in September 2022 in Gunma Prefecture, Japan. The patient continued to be symptomatic for nine days. During this outbreak, all 15 residents displayed respiratory symptoms. HRV-A was detected in 12 of the 12 samples, and phylogenetic analysis classified the strain as HRV-A type 61. HRV, COVID-19, and other respiratory infections cannot be differentiated based solely on clinical symptoms. A surveillance system to monitor them is thus needed.