文献一覧: 一般社団法人日本生物物理学会 (出版者)

1 0 0 0 OA 細胞質分裂における膜ダイナミクスの機能

著者: 竹田哲也
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.56, no.1, pp.013-017, 2016 (Released:2016-01-27)
参考文献数: 15

Cytokinesis is the final step in cell division essential for cell proliferation, tissue differentiation and animal reproduction. Cytokinesis is featured by its dramatic changes in cell shape by which a cell divides into two nascent cells with equal genomic background. The cell morphogenesis during cytokinesis is mainly driven by extensive reorganization of cytoskeleton. However, recent studies demonstrated that various membrane dynamics such as membrane trafficking and membrane remodeling also play essential roles during cytokinesis. In this review, I will overview function and regulation of the membrane dynamics during cytokinesis and discuss about its future perspectives.

2021-04-12 18:37:55
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1 0 0 0 OA ウイルス生物物理学:創薬モダリティへの貢献

著者: 前仲勝実福原秀雄橋口隆生 CAAVEIRO Jose M. M. 長門石曉黒田大祐津本浩平
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.61, no.2, pp.082-089, 2021 (Released:2021-03-25)
参考文献数: 29

Recent virological researches using biophysical methods, termed as virus biophysics or virophysics, largely contribute to the development of anti-viral drugs and vaccines. In this review, examples of structural and physicochemical analyses for representative viruses to develop drug modalities such as small compounds, antibodies, and vaccines are explained, and future direction of biophysical research for virus research is also discussed.

2021-04-07 13:03:45
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1 0 0 0 OA 酵素1分子検出から生まれたインフルエンザデジタルアッセイ

著者: 田端和仁
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.61, no.2, pp.095-101, 2021 (Released:2021-03-25)
参考文献数: 24

Digital assays, which have evolved from single-molecule detection technology, are attracting attention as a new method of measuring individual cells, proteins, and nucleic acids. The digital assays are characterized by their ability to directly measure individual molecules, enabling us to perform absolute quantification without the need for calibration curves and to determine the heterogeneity of a population. We first developed a digital assay for enzymes and applied the principle to digital ELISA and digital influenza assays. We demonstrate that the digital assays for enzymes are not only a new enzymology tools, but also have a wide range of applications such as elucidating the nature of viral populations. We will discuss how these new analytical techniques are opening up uncharted territory.

2021-03-31 17:48:07
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1 0 0 0 OA 支部だより ~中部支部の研究室紹介~

著者: 飯野亮太奥田覚島本勇太
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.61, no.2, pp.128-129, 2021 (Released:2021-03-25)

2021-03-31 08:08:44
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1 0 0 0 OA ラウエ法による時分割蛋白質結晶構造解析

著者: 坂部知平坂部貴和子
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.28, no.4, pp.209-212, 1988-07-25 (Released:2009-05-25)
参考文献数: 11

2021-03-29 16:18:40
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1 0 0 0 OA みんなの桃源郷

著者: 古谷祐詞
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.60, no.2, pp.085, 2020 (Released:2020-03-27)

2021-03-24 19:37:06
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1 0 0 0 OA 細胞・組織が作るメソスケール構造の3次元解析

著者: 太田啓介
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.58, no.5, pp.265-269, 2018 (Released:2018-09-29)
参考文献数: 4
被引用文献数: 1 1

2021-03-24 09:24:32
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1 0 0 0 OA 結晶構造から見えてきたチャネルロドプシンの分子メカニズム

著者: 加藤英明濡木理
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.53, no.5, pp.246-249, 2013 (Released:2013-09-25)
参考文献数: 20
被引用文献数: 1

Channelrhodopsin (ChR) is a light-gated cation channel derived from algae. Since the inward flow of cations triggers the neuron firing, neurons expressing ChRs can be optically controlled even within freely moving mammals. Although ChR has been broadly applied to neuroscience research, little is known about its molecular mechanisms. We determined the crystal structure of chimeric ChR at 2.3 Å resolution and revealed its molecular architecture. The integration of structural and electrophysiological analyses provided insight into the molecular basis for the channel function of ChR, and paved the way for the principled design of ChR variants with novel properties.

2021-03-04 07:30:54
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1 0 0 0 大沢さん追悼:50年先への千里眼(4) 50年先の生物物理学にのこせるものは

著者: 冨樫祐一
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.60, no.3, pp.185-187, 2020

2021-03-02 03:00:07
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1 0 0 0 大沢さん追悼:50年先への千里眼(7) ランダムではない揺らぎをもつ細胞の計算能力

著者: 青野真士
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.60, no.4, pp.247-248, 2020

2021-03-02 02:45:05
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1 0 0 0 大沢さん追悼:50年先への千里眼(6) 生物物理に根付く多様性を許容する文化

著者: 根岸瑠美
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.60, no.4, pp.245-246, 2020

2021-03-02 02:15:06
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1 0 0 0 OA グルコースのエネルギーとは?

著者: 福嶋義博丑丸眞
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.43, no.3, pp.150-153, 2003 (Released:2003-05-23)

2021-02-22 20:08:50
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1 0 0 0 OA 1PD060 生体内核変換を示唆する種々の測定結果(第25報) : Saccharomyces cerevisiaeを用いての精査(3)

著者: 小牧久時谷喜雄正木信男 Pappas Panos T.
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.39, no.supplement, pp.S99, 1999-09-02 (Released:2017-05-01)
参考文献数: 6

2021-02-21 22:12:14
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1 0 0 0 OA Cl–ポンプロドプシンの分子機構とH+ポンプへの機能変換

著者: 菊川峰志
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.61, no.1, pp.012-015, 2021 (Released:2021-01-29)
参考文献数: 12

Cl–-pump rhodopsin is the second discovered microbial rhodopsin and functions as light-driven Cl– pump. The physiological significance of the Cl– pump has not been fully resolved. However, its functional mechanism has been studied as a model system of anion transporters. In this review, the variation and functional mechanisms of Cl–-pump rhodopsins were summarized. After 2014, novel Cl–-pump groups were discovered in marine and terrestrial bacteria and were revealed to have unique characteristics. The most recently identified protein has close similarity with the H+-pump rhodopsin and begins to pump H+ outwardly by only a single amino acid replacement.

2021-02-09 17:09:57
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1 0 0 0 OA シグナル伝達機構による時間情報コード

著者: 久保田浩行黒田真也
出版者: 一般社団法人日本生物物理学会
雑誌: 生物物理 (ISSN:05824052)
巻号頁・発行日: vol.53, no.4, pp.184-189, 2013 (Released:2013-07-25)
参考文献数: 18

Cellular responses, such as cell fate decision and hormonal regulations, can be regulated by distinct temporal patterns of signaling molecules. However, how temporal patterns of signaling molecules determine the cellular responses remains largely unknown. Recently, we have proposed the concept of “temporal coding”, by which a single molecular species can encode multiple information through its temporal patterns. We found that signaling pathways can process information of stimulation patterns depending on their network motif and kinetics, and cells can regulate downstream molecules depending on stimulation pattern. Thus, “temporal coding” appears to serve as an information-embedding strategy to elicit specific cellular responses.