著者
片山 文彦
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.41, no.3, pp.202-220, 1971-03
著者
小川 雅美
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.64, no.5, pp.418-423, 1994-05-25
著者
押谷 仁
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 = Journal of Tokyo Women's Medical University (ISSN:00409022)
巻号頁・発行日
vol.86, no.2, pp.56-60, 2016-04

第81回東京女子医科大学学会総会 平成27年10月10日(土) 東京女子医科大学弥生記念講堂
著者
加藤 文代 布田 伸一
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.87, no.Extra1, pp.E40-E47, 2017-05-31 (Released:2017-07-31)
参考文献数
31

Post-transplant lymphoproliferative disorders (PTLD) remain a significant cause of morbidity and mortality after pediatric heart transplantation. More than 80 % of cases are of B-cell origin and are positive for Epstein-Barr virus (EBV). The pathogenesis of EBV-positive PTLD appears to be correlated with the uncontrolled proliferation of latently EBV-infected B cells arising from a lack of EBV-specific cytotoxic T-lymphocyte function. PTLD includes a spectrum of diseases ranging from reactive lymphoid proliferation to malignant lymphoma. The risk factors underlying the development of PTLD include the degree of immunosuppression, the EBV serostatus of the recipient, the time since transplantation, and the recipient's age and ethnicity. In the pediatric age group, most PTLD cases occur in EBV-negative recipients of EBV-positive donor organs. As part of routine evaluations of patients with a high risk of PTLD, EBV monitoring is useful for the early detection of this complication. A high index of suspicion is key to an early and accurate diagnosis of PTLD. The subsequent therapeutic goals are the eradication of PTLD and the preservation of graft function. The treatment outcomes for PTLD have steadily improved over the past decade, partly because of the availability of rituximab and everolimus.
著者
永坂 鉄夫
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.63, no.1, pp.62-67, 1993-01-25
著者
檜垣 祐子
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 = Journal of Tokyo Women's Medical University (ISSN:00409022)
巻号頁・発行日
vol.85, no.5, pp.147-150, 2015-10

アトピー性皮膚炎は小児に多いありふれた疾患で、通常、思春期前に軽快するが、一部の症例では思春期から成人に至るまで遷延する。このような症例では、心理社会的ストレスが主な悪化因子となっており、そのおもなものは、職場や家庭における人間関係の問題である。ストレス因子は不適切な対処行動としての掻破行動を誘発し、皮疹の悪化を招く。治療にあたっては、ストレス対処スキルの向上を目指すとともに、この掻破行動の修正が重要で、行動の問題としての掻破行動が減ることで皮疹は著明に改善する。アトピー性皮膚炎から派生する問題ではステロイド忌避が大きい。アトピー性皮膚炎患者が精神疾患を合併する場合は、メンタルケア科との併診が必要である。
著者
大澤 美貴雄
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.59, no.6, pp.499-513, 1989-06-25
著者
駒形 依子 小川 正樹 橋本 誠司 櫻井 理乃 菊浦 沙織 寺田 美里 土山 史佳 佐々木 かりん 金野 潤 三谷 穣 牧野 康男 松田 義雄 松井 英雄
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.82, no.5, pp.344, 2012-10-25

第8回東京女子医科大学メンタルヘルス研究会 平成24年7月18日(水)18:15~20:00 東京女子医科大学 総合外来センター5F大会議室
著者
村田 光範
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.67, no.臨時増刊号, pp.E2-E9, 1997-07-30

Since the end of 2nd World War, Japan has seen quite rapid socioeconomical developments. With these developments the physical size of Japanese children has increased, but the final size, especially of the stature is still shorter than that of Caucasians. We have very interesting results from the investigation of skeletal growth in the children aged from 7 to 18 years old, using the TW2 bone age estimation method. The subjects were about 100 boys and girls in each age group from 7 to 18 years old in the Tokyo metropolitan area. In Japanese children the tempo of "RUS" maturation is almost equal to that of TW2 from 7 to 10 years old and from to 9 years old in boys and in girls respectively, but after 10 years old and 9 years old in boys and in girls respectively, the tempo is more rapid than that of TW2. Japanese children may have a different tempo of skeletal maturation during pubertal growth from that of Caucasian children. This difference in the tempo of skeletal maturation, probably genetic, between Japanese and Caucasians, especially that of RUS, during pubertal growth may be one of the main causes of the final difference in the stature of the two groups.
著者
森實 敏夫 小島原 典子
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.88, no.Extra1, pp.E38-E46, 2018-01-31 (Released:2018-02-28)
参考文献数
20

In systematic reviews, the evaluation of the risk of bias and indirectness on effect estimates is essential to assess the certainty of the body of evidence. A program in the programming language R was developed to execute a meta-analysis adjusting for the effects of biases after assessing bias magnitudes, directions, and uncertainty. The program visualizes the effects of biases by creating an overlayered forest plot of bias-adjusted and -unadjusted values. When performing meta-analyses and sensitivity analyses, this helps assess the certainty of the body of evidence by setting various estimates for biases and indirectness of individual studies as risk ratios and standard deviations or 95 % confidence intervals.
著者
松岡 尚史
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.87, no.Extra1, pp.E48-E53, 2017-05-31 (Released:2017-07-31)
参考文献数
8

The association between secular trends in height and changes in bone maturation was investigated. The first group of subjects consisted of a total of 1,057 girls and 1,055 boys who participated in a health research project conducted in Japan and China in 1986. The second group of subjects consisted of a total of 382 girls and 629 boys who participated in a research project examining bone mineral density in 1996. The skeletal maturity score was assessed using the Tanner-Whitehouse 2 RUS method. The Wilcoxon rank sum test was then applied to examine the significance of the differences between the 1986 and the 1996 groups. The 1996 children had not matured more quickly than the 1986 children, and the children in both groups reached the given scores at almost the same ages. In girls, there was a small difference between the groups at 7 years of age, but this difference decreased from the age of 8 years onwards. Some apparent differences arose at ages 14 and 15 years, but these differences ceased by the age of 16 years in girls. No differences were found for boys between the ages of 7 and 17 years, except for 12-year-olds. We did not detect a notable difference in bone maturation between the 1986 and 1996 groups of children, and no differences in height were observed during the same period. Our findings suggest that bone maturation reflects the secular trend in growth.
著者
川村 恵子 Keiko KAWAMURA
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.58, no.11, pp.1079-1091, 1988-11-25
著者
入來 正躬 Masami IRIKI
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.63, no.1, pp.48-55, 1993-01-25
著者
森 臨太郎
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.88, no.Extra1, pp.E10-E15, 2018-01-31 (Released:2018-02-28)
参考文献数
6

It has been 15 years since clinical practice guidelines were introduced and implemented in Japan, and the quality of the guidelines has dramatically improved. Clinical practice guidelines, health technology assessments, and systematic reviews share common methodologies, and combinations of these programs have flourished and/or been explored in many organizations and countries such as the National Institute of Clinical and Care Excellence (United Kingdom). In this review, the relationship among the three programs in Japan was explored. Systematic reviews are an essential methodology for both clinical practice guidelines and health technology assessment. Promoting the collaborative use of the three programs in Japan should be encouraged, and the minimum requirements for a "systematic review" should be determined. The role of clinical practice guidelines in the national health policy should also be determined to check whether Japanese clinical practice guidelines should be assessed against the advancing guideline development, reporting and evaluation in health care (AGREE) II and whether they should incorporate economic analyses.
著者
春日 紀子 高橋 宏之 坂梨 洋 安藤 大吾 小林 利道 増田 崇光 篠原 潤 佐藤 孝幸 磯谷 栄二
出版者
東京女子医科大学学会
雑誌
東京女子医科大学雑誌 (ISSN:00409022)
巻号頁・発行日
vol.83, no.1, pp.50-50, 2013-02-25

第347回東京女子医科大学学会例会 平成25年2月23日(土) 総合外来センター5階 大会議室