著者
金指 あや子 菊地 賢 杉山 正幸 石田 清 永光 輝義 鈴木 和次郎
出版者
日本生態学会
雑誌
保全生態学研究 (ISSN:13424327)
巻号頁・発行日
vol.19, no.2, pp.139-149, 2014-11-30

環境省レッドリストで絶滅危惧II 類に指定されている日本固有種ハナノキAcer pycnanthum(ムクロジ科)の最大の自生地である岐阜県中津川市千旦林において、ハナノキ個体群の分布と構造を明らかにし、その成立について考察した。調査は、2カ所の自生地(A区:7.5ha、B区:0.9ha)で行った。自生地はいずれも造林地や広葉樹二次林に覆われているが、A区には、ため池沿いの湿地や水田跡地などの開放的な環境も含まれる。A区では胸高周囲15cm以上の幹を持つハナノキ個体が785個体、B区では44個体が確認され、A区は個体数規模においてハナノキの我が国最大の自生地であると認められた。A区では、逆J字型のサイズ構造を示し、若い未成熟個体を多く含んでいたが、B区は幅の広い一山型分布を示した。現存個体の死亡にともなう地域個体群の絶滅が危惧されるB区に対し、A区では更新木の存在により個体群の存続が見込まれる。こうした個体群構造の違いは、開放的環境の有無や森林の取り扱い履歴に起因する。特に過去、複数回行われたスギ、ヒノキなど針葉樹植林時の森林伐採が、ハナノキの順次更新をもたらした結果、A区における最大規模の個体数の維持に寄与していると考えられた。多くのハナノキ自生地では実生の更新がほとんど見られず個体群の衰退が危惧される中、ハナノキの保全管理のモデルケースとして、本区域のハナノキ個体群の動態を注意深く見守り、個体群の持続機構を解明するとともに、更新サイトを確保するための上層間伐(受光伐)などの管理を行う必要がある。
著者
中島 誠 中木原 由佳 高橋 武士 野間口 寛 寺師 守彦 林 秀樹 杉山 正
出版者
一般社団法人日本医薬品情報学会
雑誌
医薬品情報学 (ISSN:13451464)
巻号頁・発行日
vol.18, no.1, pp.13-21, 2016 (Released:2016-06-13)
参考文献数
19

Objective: We have used therapeutic drug monitoring (TDM) analysis software to set the initial dose of vancomycin in our hospital.  In contrast, the TDM guideline, in which the initial dose of vancomycin per body weight was set, was published in 2012.  We looked forward with utilizing the TDM guideline in the clinical setting, after which we conducted multiple surveys to determine the important points of the TDM guideline.Methods: We surveyed patients treated with vancomycin, in whom the initial dose was set using the TDM analysis software and the concordance rate between the vancomycin dose set with the software and that set with the TDM guideline.Results: The concordance rate of vancomycin dose was 42.1%.  The mean age of the high-dose group (vancomycin dose higher than that recommended by the TDM guideline), was younger than that of the recommended-dose group.  Additionally, the mean body weight of the high-dose group was significantly lower than that of the recommended-dose group.  The corrected creatinine clearance of the low-dose group was significantly lower than that of the recommended-dose group.Conclusion: Our results suggest that when the initial dose is set after referring the TDM guideline in patients who are not very high age, and having low body weight and decreased renal function, the dose may differ from the dose set by using TDM analysis software.  In addition, since the recommended dose per body weight is a range and not a single value, setting the dose appropriate to target trough concentration is necessary.
著者
杉山 正明
出版者
京都大學文學部
雑誌
京都大學文學部研究紀要 (ISSN:04529774)
巻号頁・発行日
vol.34, pp.92-150, 1995-03-31

この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。
著者
山下 修司 野口 義紘 窪田 傑文 井口 和弘 青木 慎也 多根井 重晴 中村 光浩 寺町 ひとみ 杉山 正
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.41, no.3, pp.198-204, 2015-03-10 (Released:2016-03-10)
参考文献数
15
被引用文献数
7 7

Light emitting diodes (LEDs) are widely used in lighting applications. In this study, we examined the differences in the degree of the color change of various medicines between LED lighting and fluorescent lighting. The degree of the color change of the medicines was evaluated subjectively, by the observation of the evaluator, as well as objectively, using a colorimeter. Noticeable color changes were observed in the Lasix® 20-mg Tablet(Tab), Fluitran® 2-mg Tab, and Phenobal® powder after exposure to either LED lighting or fluorescent lighting. Interestingly, the color change of the Lasix® 20-mg Tab was smaller for the LED lighting than for the fluorescent lighting.
著者
杉山 正治 柴田 みゆき 生田 敦司 齋藤 晋 宮下 晴輝
出版者
一般社団法人情報処理学会
雑誌
情報処理学会研究報告デジタルドキュメント(DD) (ISSN:09196072)
巻号頁・発行日
vol.2007, no.100, pp.37-44, 2007-09-28
被引用文献数
1

電子テキストはその利便性ゆえに広く受け入れられているが、紙媒体は電子テキストと異なる利便性を保持している。また、ブラウザを使用して電子テキストを表示する場合、ウィンドウサイズによる制約やページ遷移の問題がある。電子テキストの利便性を生かしつつ、書籍の利便性を持たせる工夫として、本研究ではページ遷移が発生しない文章表示システムのプロトタイプを Ajax を用いて構築し、「Magnifying And Simplifying System for Text EXTension Version 1.00 (略称、MaSSTExt V1.00) 」と名づけた。本システムは目次や本文などのシームレスな表示/非表示、及び拡大縮小を実現した。これにより、長大な文章であっても 1 画面のうちに情報把握が可能になる。Despite many conveniences of electronic media, paper media still have advantages because of different conveniences. When using web browser for displaying text files, its disadvantages are clear. We assumed these disadvantages come from limitation of displayable area of window or transition of pages. In this paper, a solution for these disadvantages with our prototype system is introduced: "Magnifying And Simplifying System for Text EXTension Version 1.00 (MaSSTExt V1.00)". This system is made by Ajax and work with web browser. It is enable displaying huge size of text file only one window or seamless display/not-display from index to body or annotation data.
著者
味澤 香苗 鈴木 学 林 由依 甲斐 絢子 小林 篤史 小原 道子 生木 庸寛 國府田 真綾 金地 夏実 林 秀樹 棚瀬 友啓 土屋 照雄 杉山 正
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.44, no.12, pp.599-606, 2018-12-10 (Released:2019-12-10)
参考文献数
8
被引用文献数
6

Focusing on the Pharmaceutical Intervention Records (PIR) project conducted in collaboration with the Gifu Pharmaceutical Association and Gifu Pharmaceutical University, this study analyzed characteristics and economic effects of the audit of dispensing fees for the prevention of duplications or interactions of prescription drugs by pharmacists. The pharmacists registered audit data of 1,105 prescriptions into the PIR database in 2017. For the analysis, we divided 1,105 prescriptions into those that incurred dispensing fees for the prevention of duplications or interactions of prescription drugs (the subject group) and a control group comprising other prescriptions. The reduction in drug cost per prescription was 1,689 yen in the subject group, which was significantly higher than the reduction of 563 yen in the control group. In the subject group, pharmacists tend to use a medicine notebook for identifying duplicate administrations or drug interactions. There is a high ratio of cancellation of drugs as a result of such inquiries. This is considered a factor in the reduction of the cost of drugs. The reduction per prescription in the subject group is higher than the medical fees for the prevention of duplications or interactions of prescription drugs, and it can be evaluated that activities related to preventing duplications and interactions of prescription drugs contribute to medical economy.
著者
丹羽 隆 篠田 康孝 鈴木 昭夫 大森 智史 太田 浩敏 深尾 亜由美 安田 満 北市 清幸 松浦 克彦 杉山 正 村上 啓雄 伊藤 善規
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.38, no.5, pp.273-281, 2012-05-10 (Released:2013-05-10)
参考文献数
38
被引用文献数
1 15

Antimicrobial resistance in hospitals is increasingly becoming a major problem worldwide, thus appropriate use of antimicrobial agents should be promoted. Since August 2009, our hospital has established a review system for checking prescriptions in all patients receiving antimicrobial injections according to the intervention and feedback of antimicrobial stewardship (AMS) guideline. The antimicrobial use density (AUD), duration of administration, length of hospital stay, and antimicrobial resistance in a year were compared before and after starting the intervention into AMS. Suggestions made by members of the infection control team (ICT) to the prescribers were for the major part the choice and dose elevation of antimicrobials. Most of the proposals (91%) were accepted by the prescribers. Although AUD was not changed after AMS intervention, the proportion of prolonged antimicrobial use (over 2 weeks) was significantly reduced from 5.2% to 4.1% (p=0.007), which led to the saving of costs for antibiotics (4.48 million yen/ year). The incidence of MRSA tended to decrease after AMS intervention (p=0.074). The median length of hospital stay was ultimately shortened by 1.0 day (p=0.0005), which led to an estimated saving of medical costs by 520 million yen/year. We consider that our intervention profoundly affects this cost saving. These findings suggest that the extensive intervention into AMS is effective in reducing the frequency of inappropriate use of antimicrobials, suppressing the occurrence of antimicrobial resistance, and saving medical expenses.
著者
杉山 正明
出版者
京都大学
雑誌
京都大學文學部研究紀要 (ISSN:04529774)
巻号頁・発行日
vol.34, pp.150_a-92_a, 1995-03-31

この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。
著者
杉山 正治
出版者
大谷学会
雑誌
大谷学報 = THE OTANI GAKUHO (ISSN:02876027)
巻号頁・発行日
vol.83, no.3-4, pp.1-16, 2005-06

2 0 0 0 校訂筑後志

著者
杉山正仲 小川正格共編
出版者
知新堂
巻号頁・発行日
1907
著者
杉山 正夫
出版者
JAPAN TECHNICAL ASSOCIATION OF THE PULP AND PAPER INDUSTRY
雑誌
紙パ技協誌 (ISSN:0022815X)
巻号頁・発行日
vol.52, no.1, pp.88-93,018, 1998
被引用文献数
1

従来, コート紙, 上質紙等の不良部分は人手をかけて選別しているが, 昨今平判の自動選別装置が開発されている。<BR>既製の装置については価格, 内容等で採用しにくい点もあり, 南千住製作所と共同でストリーク, スポットを主対象とする装置を開発した。主な特徴は,<BR>(1) 給紙部には, 紙折り機のノンストップ高速フィーダー採用。<BR>(2) 検出部は透過型1基 (スポット, 汚れ), 反射型2基 (ストリーク, シワ他-表・裏) の全幅CCDカメラ使用。<BR>(3) 検出ソフトは独自に開発, 集積度を高め検出力アップ。<BR>(4) 搬送部はSラップ方式, ベルトガイド採用。平坦面で検出可能。<BR>(5) オーバーラップ部には, スタートアンドトップ装置取付。<BR>稼動開始以降, 紙の安定走向と検出精度をアップさせ, 現在では64-157g/m<SUP>2</SUP>四六判が, 常用10.000枚/Hの高速で選別が可能となり問題なく稼動している。<BR>計画された数量を達成, 選別要員の削減効果もあげている。
著者
合田 和史 林 秀樹 加藤 優 上村 里菜 北夕 太郎 岩本 理央 近藤 剛弘 杉山 正
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.41, no.1, pp.44-49, 2015-01-10 (Released:2016-01-15)
参考文献数
8
被引用文献数
1

In Japan, the online distribution of over-the-counter (OTC) drugs began in June 2014. A distributor has a duty to explain information about drugs to consumers, as well as to provide OTC drugs that have undergone quality control. In this study, we investigated the method of identifying health conditions of customers and the delivery channels of OTC drugs from the distributors to consumers, using 130 online stores as our sample. First-class OTC drugs were sold at 29 stores; pharmacists are required to explain information about these drugs to consumers. All the stores set up a column on which consumers could select their health conditions on a computer screen. However, in 25 of the stores, “no problem” had been inserted in the column beforehand. This meant that consumers could buy first-class OTC drugs without indicating their health conditions. Felbinac-containing poultices, which are contraindicated for pregnant women, were sold at 99 stores. However, consumers could buy the poultices at 91 stores without providing information about pregnancy. All the stores delivered OTC drugs through home delivery services, which did not store the drugs in cool conditions. In addition, some stores delivered suppositories by mail services in summer. These findings suggest the need for online distribution of OTC drugs to incorporate an improved method of providing drug information to consumers and ensuring quality control.
著者
松浦 克彦 杉山 正 片桐 義博
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.31, no.10, pp.832-838, 2005-10-10 (Released:2011-03-04)
参考文献数
15
被引用文献数
3 4

A pharmaceutical study was carried out to evaluate the quality of five Sodium Ozagrel (OZG) injection products. The quality of these products initially and after 12 weeks and 24 weeks of accelerated stability testing was evaluated based on characteristics such as pH, foreign insoluble matter, content and impurities. One brand name injection and four generic injections were evaluated. The brand name product and one generic product were in freeze-dried form and the other three generic injections were in liquid form.The pH of one generic injection was higher than that of the others. No foreign insoluble matter was observed in any product during the period of the study. The OZG content of the freeze-dried injections was approximately equal to that indicated on the labels but that of the liquid injections was appreciably higher, one of them having at least 15 % more than the indicated content. In the accelerated stability testing, the OZG content was still around 100% of the initial content after 24 weeks, showing that it was very stable. Quaternary salts were detected in the brand name injection but the concentration was only 0.02%. The cis form of OZG was detected in one generic injection but the concentration was only 0.03%. Accelerated stability testing did not increase the quantities of these impurities. Two unknown impurities were detected in one generic injection and one of them was detected in the other three generic injections.Our study showed that there was a difference in quality between the generic injections and the brand name OZG injections in terms of pH, content and impurities, suggesting that not only cost but also quality should be considered when deciding whether to use generics or not.
著者
杉山 正明
出版者
京都大学
巻号頁・発行日
2006

博士論文
著者
杉山 正明
出版者
京都大学 (Kyoto University)
巻号頁・発行日
2006-11-24

新制・論文博士