- 著者
- by Isaac Mason = 中國回教書目 / 玫遜編
- 出版者
- 文殿閣書荘
- 巻号頁・発行日
- 1938
2 0 0 0 太陽/風力エネルギー講演論文集
2 0 0 0 <原報>プロテイン摂取とトレーニングの関係
- 著者
- 板垣 悦子/桜木 真智子/高久田 明
- 出版者
- 慶應義塾大学
- 雑誌
- 共立薬科大学研究年報 (ISSN:04529731)
- 巻号頁・発行日
- vol.41, pp.19-29, 1997-03-25
The purpose of this study was to analyze the influence of the protein powder to the effects of physical training. Female student, who had intake of the protein powder of the recommended volume, practiced physical training in the mid-level intensity. The results were as follows : 1. The skinfold thickness of the arm was reduced apparently and no change was found in the circumference of the arm. In the thorax and abdomen, both the skinfold thikness and the circumference increased. The body weight gained for period of physical training. Both the circumference and the skinfold thickness of the thigh increased. As for the lower leg, little change was found in the circumference and the skinfold thickness. 2. The influence of the protein powder to the effects of physical training was found in the body fat and in the LBM. The body fat was reduced and the LBM increased in the midst period of heavy training. After the protein powder was ceased to have as nutrition during the training period, no change was found in the LBM. 3. The systolic blood pressure after running decreased and the diastolic blood pressure increased under the condition of the present study. The heart rate also varied under the condition. The heart rate decreased before and after running. The recovery time of heart rate was found to be shorter than that before the present experiment.
2 0 0 0 IR 伝統的木工技術を導入した中学校のものづくり教育
- 著者
- 佐藤 英雄 / 萩谷 正教 / 小林 博 サトウ ヒデオ / ハギヤ マサノリ / コバヤシ ヒロシ SATO hideo / HAGIYA masanori / KOBAYASHI hiroshi
- 出版者
- 茨城大学教育学部
- 雑誌
- 茨城大学教育実践研究
- 巻号頁・発行日
- no.19, pp.25-34, 2000
- 著者
- 高橋 ひとみ/川端 秀仁/衞藤 隆
- 出版者
- 桃山学院大学
- 雑誌
- 桃山学院大学人間科学 (ISSN:09170227)
- 巻号頁・発行日
- no.45, pp.89-110, 2014-03-28
Children are given visual acuity tests at school. The purpose of the tests is to facilitate school education. There are two types of visual acuity: far- and near-vision visual acuity. Far-vision visual acuity is required, for example, when reading something written on a whiteboard in a classroom. On the other hand, near-vision visual acuity is needed when reading textbooks, notebooks, or when looking at computer screens. However, only far-vision visual acuity tests are typically included in medical examinations at public schools. We believe that a near-vision visual acuity test is necessary, and so in this paper we analyze some basic data about the relationship between children's near-vision visual acuity and their learning efficiency. For the purposes of the paper, we examined both far-vision and near-vision visual acuity, refraction test, questionnaire survey of children at an elementary school. We found that approximately20% of the children had poor, near-vision visual acuity. In addition,8% of the children had only poor near-vision visual acuity. We further found that children with poor far- and near-vision acuity had more learning difficulties compared with children of normal visual acuity. Among children with learning difficulties, the percentage of children with poor far-vision acuity was the same as that of children with poor near-vision acuity. Children whose far-vision visual acuity is found to be lacking are given remedial treatment. We therefore strongly recommend the addition of near-vision visual acuity tests in public schools so that children found to have near-vision acuity problems can be given treatment too. We have to carry out near-vision visual acuity tests and guarantee all children an opportunity to learn.
- 著者
- Federico Bossert Diego Villar ed. Viggo Mortensen [traducción de la introducción al inglés por John Hillary Palmer] = Sons of the forest : the ethnographic photography of Max Schmidt / Federico Bossert Diego Villar ed. Viggo Mortensen [English translation of introduction by John Hillary Palmer]
- 出版者
- Perceval Press
- 巻号頁・発行日
- 2013
- 著者
- 寺田 忠史 山田 雄次 野村 誠 藤本 勝彦 野村 誠 山下 純一 / 小武内 尚 武田 節夫 南 慶典 吉田 健一郎 山口 秀夫
- 出版者
- 公益社団法人日本薬学会
- 雑誌
- CHEMICAL & PHARMACEUTICAL BULLETIN (ISSN:00092363)
- 巻号頁・発行日
- vol.41, no.5, pp.907-912, 1993
- 被引用文献数
- 10
1-β-Alkyl derivatives of 1-desoxypodophyllotoxin were synthesized, and their cytotoxicity and inhibitory effects on DNA topoisomerase II (Topo-II) and tubulin polymerization were examined.The reaction of epipodophyllotoxin derivatives (1a-c) with trimethylallylsilane in the presence of boron trifluoride etherate gave 1-β-allylated compounds (2a-c). The regiochemistry and the β-stereochemistry of the 1-allyl group were confirmed by comparison of the <SUP>13</SUP>C-NMR spectra and NOE's (%) of 2c, podophyllotoxin (POD) and epipodophyllotoxin (1b). 1-β-Alkyl-1-desoxypodophyllotoxin derivatives (3-8) were prepared from 2b.None of the tested compounds (3-8) showed any inhibitory effect on Topo-II. 1-β-Propyl compound (3) and its 4'-demethyl compound (4) inhibited tubulin polymerization and the cytotoxicities of these compounds were equal to that of VP-16. 1-β-(2, 3-Dihydroxypropyl) compounds (5 and 8) and 1-β-(2, 3-diacetoxypropyl) compounds (6 and 7)showed no inhibitory effect on tubulin polymerization. Although 5 did not inhibit either Topo-II activity or tubulin polymerization, it showed a high cytotoxicity against sarcoma 180.
- 著者
- 寺田 忠史 藤本 勝彦 野村 誠 山下 純一 小武内 尚 武田 節夫 / 山田 雄次 山口 秀夫 山口 秀夫
- 出版者
- 公益社団法人日本薬学会
- 雑誌
- CHEMICAL & PHARMACEUTICAL BULLETIN (ISSN:00092363)
- 巻号頁・発行日
- vol.40, no.10, pp.2720-2727, 1992
- 被引用文献数
- 27
Various podophyllotoxin derivatives from desoxypodophyllotoxin (DPT) were synthesized to examine the structural relationships between the biological significance (cytotoxic effect, effects on DNA topoisomerase II and tubulin polymerization) in vitro and antitumor activity in vivo (L 1210).An intact 6, 7-methylenedioxy group of DPT is necessary to inhibit tubulin polymerization and topoisomerase II. 4'-Phenolic hydroxyl group of DPT is essential to inhibit DNA topoisomerase II and the inhibitory effect on DNA topoisomerase II contributes to a high cytotoxicity.The introduction of an aminoalkoxy group at 1-position of DPT enhances the inhibitory activity against DNA topoisomerase II and cytotoxic effect, causing the inhibitory activity against tubulin polymerization to disappear. The results of antitumor test in mice bearing L 1210 on podophyllotoxin derivatives suggest the following : 1) the strong cytotoxic effect itself is not a good indication of antitumor activity in vivo as long as it is associated with inhibition of tubulin polymerization. DNA topoisomerase II inhibitory effect contributes to an antitumor activity in vivo; 2) detailed measurements of cytotoxicity and inhibition on DNA topoisomerase II and tubulin polymerization in vitro are necessary to evaluate podophyllotoxin derivatives.
2 0 0 0 OA フラワーフェスティバルの見学が女子短期大学生の園芸に対する嗜好性に及ぼす影響
- 著者
- 岡田 準人/伊藤 弘顕/土橋 豊 伊藤 弘顕 土橋 豊
- 出版者
- 甲子園短期大学
- 雑誌
- 甲子園短期大学紀要 (ISSN:0912506X)
- 巻号頁・発行日
- vol.33, pp.49-54, 2015-03-25
2 0 0 0 IR 高温超伝導体YBa_2Cu_3O_<7-δ>における核四重極共鳴の横緩和
- 著者
- "鄭 実生/本安 竜平/萬本 義徳[他]" "テイ ミナル/モトヤス リュウヘイ/マンモト ヨシノリ" "Tei Minaru/Motoyasu Ryuhei/Manmoto Yoshinori"
- 雑誌
- 岡山理科大学紀要. A, 自然科学
- 巻号頁・発行日
- vol.30, pp.103-113, 1994
"The anomaly of transverse relaxation rate of YBa_2Cu_3O_<7-δ> is mainly observed at 35K and near superconducting transition. The anomaly at 35K can not be explained by dynamical factor. It is considered that the static factor causes the anomaly and it is the change of anisotropy of indirect interaction between nuclear spins because the change of shape of decay curve accompanies with the anomaly. If the interaction between electron spin and nuclear spin obeys Mila-Rice theory even in superconducting state, it is considered that the change of the anisotropy is owing to change of electron spin correlation. As for the anomaly near superconducting transition it seems to be owing to an extraordinarily slow motion such as softening."
2 0 0 0 清真古韻 : 北京牛街礼拜寺
- 著者
- "横山寿子/酒井清子" "ヨコヤマヒサコ/サカイキヨコ" "YOKOYAMAHisako/SAKAIKiyoko"
- 雑誌
- 名古屋女子大学紀要. 家政・自然編 = Journal of Nagoya Women's University. Home economics・natural science
- 巻号頁・発行日
- vol.39, pp.13-25, 1993-03-05
2 0 0 0 アラブ人のための日本語
2 0 0 0 文章の読み方および論理構造に関する判りやすさの計測
2 0 0 0 IR 経皮投与製剤FGのミッションと活動計画
2 0 0 0 IR 養護教諭による朝の校内巡視に関する実践研究
- 著者
- 斉藤 ふくみ 木下 正江 SAITO Fukumi / KINOSHITA Masae
- 出版者
- 茨城大学教育学部附属教育実践総合センター
- 雑誌
- 茨城大学教育実践研究 茨城大学教育学部附属教育実践総合センター 編 (ISSN:18833004)
- 巻号頁・発行日
- no.28, pp.113-121, 2009-11
- 被引用文献数
- 1
- 著者
- 茂木 肇 嶋村 雄哉 木村 光利 荻原 政彦 Moteki Hajime / Shimamura Yuya / Kimura Mitsutoshi / Ogihara Masahiko モテキ ハジメ シマムラ ユウヤ キムラ ミツトシ オギハラ マサヒコ
- 出版者
- 出版者:Elsevier
- 雑誌
- European Journal of Pharmacology (ISSN:00142999)
- 巻号頁・発行日
- vol.683, no.1, pp.276-284,
- 被引用文献数
- 15
We examined the effects of L-ascorbic acid and its analogues onDNA synthesis and cell proliferation. We also investigated the signaltransduction pathways involved in the induction of mitogenesis byL-ascorbic acid and its analogues using primary cultures of adult rathepatocytes. Following a 4-h serum-free cultivation, both L-ascorbic acidand its stable analogue, L-ascorbic acid 2-glucoside, time- anddose-dependently stimulated hepatocyte DNA synthesis and cellproliferation, with EC50 values of 6.46 ? 10-8 M and 3.34 ? 10-8 M,respectively. Dehydroascorbic acid (10-6 M - 10-5 M) weakly stimulatedhepatocyte mitogenesis, whereas isoascorbic acid (10-9 M ? 10-5 M) had noeffect. Hepatocyte mitogenesis induced by L-ascorbic acid or L-ascorbic acid2-glucoside was dose-dependently abolished by treatment with monoclonalantibodies against insulin-like growth factor (IGF)-I receptor, but not bytreatment with monoclonal antibodies against insulin receptor or IGF-IIreceptor. Western blot analysis showed that both L-ascorbic acid andL-ascorbic acid 2-glucoside significantly stimulated IFG-I receptor tyrosinekinase activity within 3 min, and mitogen-activated protein (MAP) kinaseactivity within 5 min. These results demonstrate that both L-ascorbic acidand L-ascorbic acid 2-glucoside induce DNA synthesis and cell proliferationin primary cultures of adult rat hepatocytes by interacting with the IGF-Ireceptor site and by activating the receptor tyrosine kinase/MAP kinasepathway.
2 0 0 0 図書館調査研究リポート
- 著者
- 国立国会図書館 [編集] = NDL research report / National Diet Library
- 出版者
- 国立国会図書館
- 巻号頁・発行日
- 2003