著者

Christopher P. Hudec Mona J. Boord Craig E. Griffin

出版者

日本獣医皮膚科学会

雑誌

獣医臨床皮膚科 (ISSN:13476416)

巻号頁・発行日

vol.25, no.3, pp.143-147, 2019 (Released:2019-09-20)

参考文献数

7

被引用文献数

3

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ハチ毒免疫療法は刺咬症による毒素に対する致死的な反応の可能性を減弱させる。ハチ毒免疫療法は安定化のためにヒトアルブミンが必要である。本症例はハチ毒免疫療法の最中にアナフィラキシーを発症したラブラドールレトリーバーの1例である。比内試験によりヒトアルブミンに対する継続的な感作が認められた。ハチ毒免疫療法がヒトアルブミンに対する感作のリスク因子であるかについて調べるため,ハチ毒免疫療法が施された4頭の犬と6頭の健常犬,6頭のアトピー犬に比内試験を行った。1頭の犬がヒトアルブミンに対して反応を示した。この犬はハチ毒免疫療法で治療されているが臨床症状は示していない。ヒトアルブミンを含むハチ毒免疫療法がこのタンパクに対する感作とアナフィラキシーを起こす可能性がある。

著者

Arisa Nishihara Shin Haruta Shawn E. McGlynn Vera Thiel Katsumi Matsuura

出版者

Japanese Society of Microbial Ecology · The Japanese Society of Soil Microbiology

雑誌

Microbes and Environments (ISSN:13426311)

巻号頁・発行日

vol.33, no.1, pp.10-18, 2018 (Released:2018-03-29)

参考文献数

77

被引用文献数

21

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The activity of nitrogen fixation measured by acetylene reduction was examined in chemosynthetic microbial mats at 72–75°C in slightly-alkaline sulfidic hot springs in Nakabusa, Japan. Nitrogenase activity markedly varied from sampling to sampling. Nitrogenase activity did not correlate with methane production, but was detected in samples showing methane production levels less than the maximum amount, indicating a possible redox dependency of nitrogenase activity. Nitrogenase activity was not affected by 2-bromo-ethane sulfonate, an inhibitor of methanogenesis. However, it was inhibited by the addition of molybdate, an inhibitor of sulfate reduction and sulfur disproportionation, suggesting the involvement of sulfate-reducing or sulfur-disproportionating organisms. Nitrogenase activity was affected by different O2 concentrations in the gas phase, again supporting the hypothesis of a redox potential dependency, and was decreased by the dispersion of mats with a homogenizer. The loss of activity that occurred from dispersion was partially recovered by the addition of H2, sulfate, and carbon dioxide. These results suggested that the observed activity of nitrogen fixation was related to chemoautotrophic sulfate reducers, and fixation may be active in a limited range of ambient redox potential. Since thermophilic chemosynthetic communities may resemble ancient microbial communities before the appearance of photosynthesis, the present results may be useful when considering the ancient nitrogen cycle on earth.

著者

Arisa Nishihara Vera Thiel Katsumi Matsuura Shawn E. McGlynn Shin Haruta

出版者

Japanese Society of Microbial Ecology · The Japanese Society of Soil Microbiology

雑誌

Microbes and Environments (ISSN:13426311)

巻号頁・発行日

vol.33, no.4, pp.357-365, 2018 (Released:2018-12-28)

参考文献数

79

被引用文献数

1 23

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Chemosynthetic microbial communities develop and form dense cell aggregates in slightly alkaline sulfidic hot springs in the temperature range of 70–86°C at Nakabusa, Japan. Nitrogenase activity has recently been detected in the microbial communities collected. To identify possible members capable of nitrogen fixation, we examined the diversities of 16S rRNA and nitrogenase reductase (NifH) gene sequences in four types of chemosynthetic communities with visually different colors and thicknesses. The results of a 16S rRNA gene analysis indicated that all four microbial communities had similar bacterial constituents; the phylum Aquificae was the dominant member, followed in abundance by Thermodesulfobacteria, Firmicutes, and Thermotogae. Most of the NifH sequences were related to sequences reported in hydrothermal vents and terrestrial hot springs. The results of a phylogenetic analysis of NifH sequences revealed diversity in this gene among the communities collected, distributed within 7 phylogenetic groups. NifH sequences affiliated with Aquificae (Hydrogenobacter/Thermocrinis) and Firmicutes (Caldicellulosiruptor) were abundant. At least two different energy metabolic pathways appeared to be related to nitrogen fixation in the communities analyzed; aerobic sulfur/hydrogen-oxidizing bacteria in Aquificae and fermentative bacteria in Firmicutes. The metabolic characteristics of these two dominant phyla differed from those previously inferred from nitrogenase activity assays on chemosynthetic communities, which were associated with hydrogen-dependent autotrophic sulfate reduction. These assays may correspond to the observed NifH sequences that are distantly related to the known species of Thermodesulfovibrio sp. (Nitrospirae) detected in the present study. The activities of nitrogen-fixing organisms in communities may depend on redox states as well as the availability of electron donors, acceptors, and carbon sources.

著者

フレッド・E・インボー ジョン・E・リード ジョセフ・P・バックリー著 小中信幸 渡部保夫共訳

出版者

ぎょうせい

巻号頁・発行日

1990

著者

渡辺 宏久 Bagarinao E. 祖父江 元 伊藤 瑞規 前澤 聡 寳珠山 稔 森 大輔 田邊 宏樹

出版者

名古屋大学

雑誌

挑戦的萌芽研究

巻号頁・発行日

2015-04-01

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本研究では、fMRIと脳波 (EEG) を組み合わせたEEG-fMRIを用い、fMRIの有する高い空間分解能を活かした解析に加え、脳波の有する高い時間分解能生を活かした解析を組み合わせて、ヒトの高次脳機能神経回路や精神症状をサブミリセカンドで観察出来るシステムを構築した。我々の解析方法を用いることで、作業記憶課題を用いた脳活動の観察では、認知課題中に1秒未満で連続的に変化する脳活動を観察可能であった。またてんかん活動を観察しつつ同定した焦点は、手術により確認したそれと良く一致していた。我々の開発した解析手法は、高い空間分解能で1秒未満の連続的な脳活動変化を捉えられる。

著者

Blake David Robson Robert E.

出版者

THE PHYSICAL SOCIETY OF JAPAN

雑誌

Journal of the Physical Society of Japan (ISSN:00319015)

巻号頁・発行日

vol.70, no.12, pp.3556-3559, 2001-12-15

被引用文献数

4

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In a recent article [Yamamoto and Ikuta: J. Phys. Soc. Jpn. 68 (1999) 2602] state that the true origin of negative differential conductivity (NDC) has never been shown, in apparent contradiction of claims made in earlier papers [Z. Lj et al..: Aust. J. Phys. 37 (1984) 23; R. E. Robson: ibid. 37 (1984) 35]. In the present paper, we argue that the true origin of NDC has indeed been explained satisfactorily, and present a comprehensive range of calculations for a number of cases, demonstrating the effectiveness of momentum transfer theory [Hot electron transport in semiconductors (Springer, Berlin, 1985) p. 82] for understanding NDC from both a qualitative and quantitative perspective.

著者

Richard E. Mayer

出版者

The Japanese Association of Educational Psychology

雑誌

教育心理学年報 (ISSN:04529650)

巻号頁・発行日

vol.41, pp.27-29, 2002-03-30 (Released:2012-12-11)

被引用文献数

5 25

著者

Goldman E.B. Thorsos E. Woodall D. Yaakobi B. Goldman L.M. Delettrez J. Hoose J. Jackel S. Leppelmeier G.W. Lubin M.J. Nee A. Pelah I.

出版者

一般社団法人 レーザー学会

雑誌

レーザー研究 (ISSN:03870200)

巻号頁・発行日

vol.4, no.4, pp.229-244, 1977

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We report here on the theoretical interpretation of results related to compression experiments performed on the University of Rochester's four beam laser system. The experimental results show volume reduction on the order of 300 with compressed electron temperatures on the order of 1 KeV, critical surface temperatures also about 1 KeV and a density plateau in the vicinity of the critical surface. The theoretical work focusses on the effect of absorption time history, of reduced flux limits and of variation of the suprathermal electron distribution on the replication of these experiments.

著者

Tago Masaki Yamashita Shun Matsufuji Noriko Fujiwara Motoshi Katsuki Naoko E Nishiyama Masanori Yamashita Shu-ichi

出版者

日本病院総合診療医学会

雑誌

日本病院総合診療医学会雑誌 (ISSN:21858136)

巻号頁・発行日

vol.14, no.6, pp.575-577, 2018-11

著者

BOWER C. E.

雑誌

Journal of Fisheries Research Board of Canada

巻号頁・発行日

vol.35, pp.1012-1026, 1978

被引用文献数

10

著者

Kibugu J.K. Mdachi R.E. Kagira J.M. Muchiri M.W. Makumi J.N. Ngeranwa J.J.N. Auma J. E. Ngae G.N.

出版者

National Research Center for Protozoan Diseases

雑誌

The journal of protozoology research (ISSN:09174427)

巻号頁・発行日

vol.21, no.2, pp.59-69, 2011-12

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Through immuno-suppression, aflatoxins could affect drug and vaccine efficacy. Such effects have not been evaluated in treatment of many diseases including trypanosomiasis. We assessed the effect of aflatoxin B1 on the efficacy of suramin, the drug used for treatment of early stage sleeping sickness, in a murine model. Mice were fed daily on a diet containing 0.50 mg aflatoxin/kg body weight or a placebo. They were infected with Trypanosoma brucei rhodesiense on day 7 post-aflatoxin exposure and then treated with one of 6 different doses of suramin (4.0, 4.5, 5.0, 5.5, 6.0 and 6.5 mg/kg body weight) at the onset of parasitemia. The mice were fed on aflatoxin diet for 30 days and the curative dose values (CD50, 75, and 90) computed and compared using a logistic linear regression model. Aflatoxin B1 induced transient protection of the host against T. b. rhodesiense infection and a consistent increase in suramin CD values in the mice suggesting reduced drug efficacy. Aflatoxicosis hindered curative treatment of T. b. rhodesiense infection in mice, and may contribute to reduced efficacy of suramin during treatment of sleeping sickness in man.

著者

E.E.ケァンズ著

出版者

いのちのことば社(発売)

巻号頁・発行日

1957

著者

RYZEN E.

雑誌

Arch Intern Med

巻号頁・発行日

vol.145, pp.449-452, 1985

被引用文献数

2 16

著者

L.ポーリング E.キャメロン共著 村田晃[ほか]共訳

出版者

共立出版

巻号頁・発行日

1981

著者

ジョセフ・E・スティグリッツ リンダ・ビルムズ著 楡井浩一訳

出版者

徳間書店

巻号頁・発行日

2008

著者

竹谷 怜子 辻本 江美 小野 久江 R. Taketani E. Tsujimoto Hisae Ono

雑誌

臨床教育心理学研究

巻号頁・発行日

no.38, pp.19-22, 2012-03-25

著者

Saurav Uppal Anthony E. DeCicco Anselma Intini Richard A. Josephson

出版者

International Heart Journal Association

雑誌

International Heart Journal (ISSN:13492365)

巻号頁・発行日

vol.59, no.3, pp.622-625, 2018-05-31 (Released:2018-05-30)

参考文献数

13

被引用文献数

10

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Allergic reactions to contrast media are a frequently reported complication of coronary angiography. The majority of patients experience mild, self-limited episodes, but in rare cases patients may experience severe, persistent symptoms. A strategy of premedication with corticosteroids and anti-histamines and an optimal selection of contrast agent is almost always successful in averting contrast reactions, yet a select few patients will continue to have breakthrough events. This is a case of recurrent, severe allergy to contrast media despite standard precautions complicating the treatment of non-ST elevation myocardial infarction (NSTEMI). Our patient was successfully managed with a strategy of rapid desensitization to iodinated contrast media achieved by administering progressively incremental doses of the media.

著者

平井 岳根 村尾 俊裕 Brito Manuel E. 鳥山 素弘 神崎 修三

出版者

公益社団法人日本セラミックス協会

雑誌

日本セラミックス協会学術論文誌 : Nippon Seramikkusu Kyokai gakujutsu ronbunshi (ISSN:18821022)

巻号頁・発行日

vol.110, no.1284, pp.784-788, 2002-08-01

参考文献数

22

被引用文献数

1

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α'-SiAlON containing Sr, having a large ionic radius, was obtained by hot-pressing. Sr was accommodated in α'-SiAlON in conjunction with Y. The effect of adding Sr to Y-α'-SiAlON on thermal conductivity and mechanical properties was studied. Thermal conductivity decreased from 11.9 W/m・K to 6.2 W/m・K with increasing addition of Sr, due to increasing of phonon scattering both in the lattice and at the grain boundary. Bending strength increased from 460 MPa to 860 MPa with increasing addition of Sr. The increase in bending strength can be associated with grain size refinement and fracture toughness. Fracture toughness also increased with increasing addition of Sr.

著者

Anne E. Duggan traduit de l'anglais par Jean-François Cornu

出版者

Presses universitaires de Rennes

巻号頁・発行日

2015

著者

William. E. WILSON

出版者

Japan Society for Atmospheric Environment

雑誌

大気環境学会誌 (ISSN:13414178)

巻号頁・発行日

vol.33, no.3, pp.A67-A76, 1998-05-10 (Released:2011-11-08)

参考文献数

25

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On July 18, 1997, EPA promulgated new standards for fine particles, with PM2.5 as the indicator (15μg/m3, annual average; 65μg/m3, 24-hour average). EPA also retained the existing levels of the PM10 standards (50μg/m3, annual average; 150μg/m3, 24-hour average) to pro-. tect against exposure to coarse particles. This decision was based on an extensive review of the scientific information regarding effects of PM. The upper 50% cut point of 10μm was chosen because it provides a measure of thoracic particles (i.e., those particles entering the lung). The 50% cut point 2.5μm was chosen to divide thoracic particles into fine and course particles because of their differences in sources, composition, and properties (chemical, physical, and biological). The time required for determining compliance or noncompliance with the revised PM standards is such that the next periodic review of the PM standards (required every 5 years) will take place before new particle control measures will be required. Monitoring requirements for determining compliance and research needed for the next review have been identified by EPA. Research needs include improved measurement techniques for finemode particles.