文献一覧: ビタミン (雑誌)

3 0 0 0 OA 4.ビタミンE誘導体のアポトーシス誘導作用 : 構造-活性相関

著者: 真鍋幸恵福澤健治
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.78, no.3, pp.152-155, 2004-03-25 (Released:2017-10-10)
参考文献数: 9

2019-06-05 09:08:39
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3 0 0 0 OA 胆汁酸代謝とビタミンD受容体

著者: 槇島誠
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.85, no.2, pp.47-56, 2011-02-25 (Released:2017-10-10)
参考文献数: 51

Nuclear receptors belonging to the NR1H and NR1I subfamilies, including vitamin D receptor (VDR, NR1I1), control cholesterol and bile acid metabolism. Bile acids are detergents essential for the digestion and intestinal absorption of hydrophobic nutrients, such as triacylglycerol, cholesterol and lipid-soluble vitamins, including vitamin D.Primary bile acids are generated from cholesterol and are secreted in bile as glycine and taurine conjugates. The intestinal microflora convert the primary bile acids to the secondary bile acids, including lithocholic acid (LCA). VDR, a receptor for 1,25-dihydroxyvitamin D_3(1,25(OH)_2D_3), acts as a bile acid receptor with specificity for the secondary bile acid LCA and its derivatives. VDR activation by 1,25(OH)_2D_3 or LCA induces the xenobiotic metabolism of bile acids. Synthetic LCA derivatives induce tissue VDR activation without inducing hypercalcemia in mice. VDR acts as a bile acid sensor as well as an endocrine receptor for vitamin D signaling.

2019-04-06 07:43:28
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3 0 0 0 レチナールタンパク質と霊鳥類の色覚

著者: 吉澤透茅田誠也
出版者: 日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.68, no.8, pp.478-480, 1994-08-25

2015-06-16 16:20:30
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https://ci.nii.ac.jp/naid/110002848077

2 0 0 0 OA イオン飲料水などの多飲によるビタミンB1 欠乏症(特集:臨床におけるビタミン・バイオファクターの有用性)

著者: 奥村彰久
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.93, no.7, pp.283-290, 2019-07-25 (Released:2020-07-31)

The Committee on Pediatric Nutrition of the Child Health Consortium of Japan investigated vitamin B1 deficiency caused by excessive consumption of ionic beverages. In the national survey, we obtained clinical data from 33 children. Twenty-one children had a problem with the nurturing home environment. The median duration of excessive ionic beverage intake was 3.5 months and the daily intake was 1,000 mL or more in 25 children. Infectious diseases were the most common reason for excessive ionic beverage consumption. The symptoms of vitamin B1 deficiency were nonspecific, and about half of the cases had neurological sequelae. The questionnaire survey of parents on their awareness of ionic beverages and their actual usage of ionic beverages for their young children showed to be generally good. Having a positive opinion about the benefits of ionic beverages was associated with the risk of their excessive consumption. The questionnaire survey of pediatric practitioners showed that pediatricians’ attitudes toward children’s consumption of ionic beverages were generally appropriate. Pediatric specialists showed more appropriate attitudes toward children’s consumption of ionic beverages than non-pediatric specialists. It will be important to notify the potential harm of excessive ionic beverage consumption to prevent the occurrence of new cases.

2024-01-15 07:56:38
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2 0 0 0 OA チアミンとプリオンタンパク質

著者: 山元誉子廣村信田鶴谷(村山) 恵子
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.88, no.12, pp.616-618, 2014-12-25 (Released:2017-08-10)

2024-01-15 07:00:49
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2 0 0 0 OA 神経管閉鎖障害:葉酸摂取による予防

著者: 近藤厚生師田信人岡井いくよ山本憲朗近藤厚哉渡邉智之
出版者: 公益社団法人日本ビタミン学会
雑誌: ビタミン (ISSN:0006386X)
巻号頁・発行日: vol.92, no.1, pp.1-17, 2018 (Released:2019-01-31)

The Medical Research Council vitamin study has unequivocally demonstrated in 1991 that 72 percent of recurrence of neural tube defects (meningomyelocele and anencephaly) were successfully prevented by taking 4 mg of folic acid periconceptionally. Of 87 countries whose major staples were forti¿ed with folic acid, micronutrients, or minerals, 81 have implemented food forti¿cation with folic acid and observed a significant decline of neural tube defect prevalence following the fortification program. The Ministry of Health and Welfare in Japan recommended in 2000 that women planning to conceive should take folic acid supplements of 400 μg daily. During the past 16 years, however, prevalence of meningomyelocele has not decreased but remains rather stable, from 5 to 6 per 10,000 births (live births and stillbirths). A total of 542 newborns, i.e., 502 with meningomyelocele and 40 with anencephaly, were estimated to be born in the year of 2015. Furthermore, if fetuses terminated during pregnancy were counted, the real number of them would probably climb up to 2169 and would be 4 times as many as the number of¿cially reported. Since longstanding recommendations alone have not worked properly, we would like to urge the government to implement mandatory food forti¿cation with folic acid, which will certainly decrease the number of afÀicted patients and lead to economic bene¿ts and signi¿cant reduction in the cost burden on the healthcare system and healthcare payers.