著者
田中 秀夫
出版者
京都大学経済学会
雑誌
經濟論叢 (ISSN:00130273)
巻号頁・発行日
vol.181, no.3, pp.206-226, 2008-03
著者
Nguyen-Van Triet Hori Noriyuki
出版者
Institution of Engineering and Technology
雑誌
IET Control Theory & Applications (ISSN:17518644)
巻号頁・発行日
vol.7, no.1, pp.80-89, 2013-01
被引用文献数
14 4

A new approach is proposed for obtaining discrete-time models of a non-linear autonomous continuous-time system based on classification of, what is called in this study, a discrete-time integration gain. The models are expressed as a product of this gain and the system function that has the same structure as that of the continuous-time system. Sufficient conditions on this gain to make the model exact, in the sense defined in this study, are presented. A new discrete-time model is proposed for non-linear systems, which is approximate in general, but exact for linear systems. The method is applicable to any system that has a Jacobian matrix. As examples, van der Pol and Lorenz oscillators are examined and simulated to show that the proposed discrete-time models perform better than other discrete-time models that are known to the authors to be on-line computable, and tends to retain such key features as limit cycles and chaos, even for relatively large sampling periods.
著者
Kim Hyojung Sakamoto Kazuichi
出版者
Portland Press Limited
雑誌
Cell biology international (ISSN:10656995)
巻号頁・発行日
vol.36, no.2, pp.147-153, 2012-02
被引用文献数
59 16

EGCG [(−)-epigallocatechin gallate], tea catechin, is one of the compounds that has been reported to act against obesity and diabetes. To determine the effect of EGCG on adipocyte differentiation, we treated 3T3-L1 preadipocytes with different catechins. Oil Red O staining showed significantly reduced intracellular lipid accumulation, especially with EGCG. Cell cycle analysis showed that EGCG inhibited cell proliferation by disturbing the cell cycle during the clonal expansion of 3T3-L1. RT-PCR (real-time PCR) demonstrated that EGCG noticeably reduced mRNA expression of PPARγ (peroxisome proliferator-activated receptor γ), C/EBPα (CCAAT/enhancer-binding protein α) and FoxO1 (forkhead box class O1). EGCG also caused a significant decrease in the transcription of FoxO1 – the forkhead transcription factor class O1 involved in adipocyte differentiation – via the PI3K (phosphoinositide 3-kinase)/Akt and MEK [MAPK (mitogen-activated protein kinase)/ERK (extracellular-signal-regulated kinase) kinase] pathways. These results suggest that EGCG suppresses the clonal expansion of adipocytes by inactivating FoxO1 via insulin signalling and stress-dependent MAPK pathways.
著者
三木 理斗
出版者
東京大学大学院工学系研究科 電気系工学専攻
巻号頁・発行日
2010-03-24

報告番号: ; 学位授与年月日: 2010-03-24 ; 学位の種別: 修士 ; 学位の種類: 修士(工学) ; 学位記番号: ; 研究科・専攻: 工学系研究科電気系工学専攻
著者
Ishizuka Tomoya Sankar Muniappan Yamada Yusuke Fukuzumi Shunichi Kojima Takahiko
出版者
The Royal Society of Chemistry
雑誌
Chemical communications (ISSN:13597345)
巻号頁・発行日
vol.48, no.52, pp.6481-6483, 2012-07
被引用文献数
11 3

Carboxyl groups were introduced at the peripheral positions of dodecaphenylporphyrin to link nanochannel structures with intermolecular hydrogen bonds to make the supramolecular structures robust.
著者
Iimura Yasuo Fujimoto Mari Tamura Kenji Higashi Teruo Kondo Miyuki Uchida Masao Yonebayashi Koyo Fujitake Nobuhide
出版者
Pergamon-Elsevier Ltd.
雑誌
Soil biology and biochemistry (ISSN:00380717)
巻号頁・発行日
vol.57, pp.60-67, 2013-02
被引用文献数
3 1

The dynamics of the polyaromatic structures of black humic acids (HAs), which are presumably derived from charred materials, are of significant interest for the global carbon cycle. However, the details of those dynamics are not yet well understood. We investigated differences in the degree of darkness (A600/C values), isotopic ratios (δ13C, δ15N, and Δ14C values), and 13C NMR spectra of size-separated black HAs extracted from Japanese volcanic ash soils in order to estimate the variations in the polyaromatic structures of black HAs during ca. 100 years of natural reforestation of Japanese pampas grassland. For several hundred years, all the study sites were managed similarly as grassland by burning. Subsequently, their management differed: at site G (Miscanthus sinensis: C4 plant), maintenance as of the time of this study was still performed by mowing, while at sites P (Pinus densiflora: C3 plant) and Q (Quercus crispula: C3 plant), maintenance was discontinued ca. 30 and 100 years ago, respectively. Thus, the sites range from grassland (site G) to coniferous forest (site P) to broad-leaved forest (site Q). For all HA size fractions at all sites, we found that δ13C values correlate positively with δ15N values, although the gradients are much lower for fractions of small to medium molecular size than for fractions of medium to large molecular size (denoted as lower-size and higher-size fractions, respectively). Overall, for the lower-size fractions, the contribution ratio of C4-plant-derived carbon shows a significant positive correlation with A600/C values and a negative correlation with Δ14C values, and their aromatic characteristics are greater than those of higher-size fractions within the same black HA. Furthermore, the relative proportion of lower-size fractions decreases with reforestation, especially from site P to Q. The δ13C values for all size fractions are similar for sites G and P, but are relatively low for site Q. The aryl C contents of the lower-size fractions are lower and the O-alkyl C contents and the aliphaticity (alkyl C:O-alkyl ratio) are clearly higher for sites P and Q than for site G. These results strongly suggest that stimulation of HA biodegradation might be achievable by continuous input of new plant litter during reforestation, even for lower-size HA polyaromatic structures, despite the fact that lower-size HAs biodegrade more slowly than higher-size HAs.
著者
秋山 学
出版者
株式会社 木魂社
雑誌
エポス (ISSN:02897210)
巻号頁・発行日
no.18, pp.66-73, 1999-09-10