著者

鈴木 悠 鈴木 里香 鈴木 葉子 杉原 茂考 大谷 智子

出版者

一般社団法人 日本感染症学会

雑誌

感染症学雑誌 (ISSN:03875911)

巻号頁・発行日

vol.96, no.5, pp.198-203, 2022-09-20 (Released:2022-09-20)

参考文献数

17

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Typhoid fever is common in developing countries. Even in developed countries, however, small epidemics could occur, caused not only by overseas travelers, but also by chronic carriers. Detection of chronic carriers is difficult. A small number of patients become chronic carriers and act as a source of infection if only usual treatment is given, and not complete treatment. We report two cases of typhoid fever that occurred 30 months apart in members of a family with no history of overseas travel. We examined the molecular epidemiology and identified a chronic carrier in one of the family members with gallbladder stones, and treated the carrier with antibiotics and cholecystectomy. No case of typhoid fever has occurred in the family since. No guidelines recommend examination of the gallbladder for chronic carriers, although many reports indicate gallbladder abnormalities. The above suggests that follow-up examination of typhoid fever patients should include gallbladder examination for abnormalities, especially in non-epidemic countries.

著者

稲見 昌彦 鳴海 拓志 清川 清 宮下 芳明 苗村 健 大谷 智子 鈴木 陽一 岸野 文郎 原島 博 岩田 洋夫

出版者

特定非営利活動法人 日本バーチャルリアリティ学会

雑誌

第22回日本バーチャルリアリティ学会大会

巻号頁・発行日

2017-08-21

著者

數間 貴紀 新井 麻子 大谷 智子 老谷 嘉樹 鈴木 恵子 松永 保

出版者

東京女子医科大学学会

雑誌

東京女子医科大学雑誌 (ISSN:00409022)

巻号頁・発行日

vol.93, no.2, pp.67-72, 2023-04-25 (Released:2023-04-25)

参考文献数

10

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Tay-Sachs disease involves accumulation of GM2 gangliosides in lysosomes due to a metabolic disorder of brain-abundant gangliosides. In the infantile type, death typically occurs by 3 years of age. We report brain magnetic resonance imaging (MRI) abnormalities in a case of infantile Tay-Sachs disease. The 8-month-old patient had development delay and began regression at 1 year of age. A cherry-red fundus spot and low β-hexosaminidase A (Hex A) levels in leukocytes indicated GM2 gangliosidosis. Gene analysis identified homozygous pathogenic variants in the HEXA gene, leading to Tay-Sachs disease diagnosis.At 10 months of age, brain MRI showed age-appropriate myelination. At 1 year 9 months, T2-weighted imaging showed high intensity in the subcortical white matter, with delayed myelination. At 2 years 4 months, the cerebral white matter, putamen, caudate nucleus, thalami (except ventral), middle cerebellar peduncle, and dentate nucleus showed high intensity on T2-weighted imaging. At 5 years 8 months, cerebral and basal ganglia atrophy was observed. The caudate nucleus and putamen showed high intensity on T1-weighted images and low intensity on T2-weighted images. Unlike typical infantile Tay-Sachs characteristics, higher Hex A activity in this case probably contributed to a milder phenotype and myelination acquisition during infancy.

著者

金 ジョンヒョン 橋田 朋子 大谷 智子 苗村 健

出版者

特定非営利活動法人 日本バーチャルリアリティ学会

雑誌

日本バーチャルリアリティ学会論文誌 (ISSN:1344011X)

巻号頁・発行日

vol.17, no.3, pp.289-292, 2012-09-30 (Released:2017-02-01)

参考文献数

9

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In this paper, we explain quantitatively how the auditory feedback of writing sound between ordinary pen and paper influences the efficiency of simple writing tasks. Specifically, we evaluated the speeds in the simple task of tracing Chinese characters without auditory feedback, with natural writing sound, and with emphasized writing sound. The results of this study showed that users traced more characters and also had positive impressions with emphasized writing sound feedback in contrast with the other two conditions.

著者

上岡 玲子 大谷 智子 金 じょんひょん 久保 友香 ソン ヨンア 中島 佐和子 橋田 朋子

出版者

特定非営利活動法人 日本バーチャルリアリティ学会

雑誌

日本バーチャルリアリティ学会誌 (ISSN:13426680)

巻号頁・発行日

vol.25, no.1, pp.43-44, 2020-03-31 (Released:2021-04-15)

著者

橋本 洋一郎 大谷 智子 平野 照之 平田 奈穂美 荒木 淑郎

出版者

一般社団法人 日本脳卒中学会

雑誌

脳卒中 (ISSN:09120726)

巻号頁・発行日

vol.13, no.2, pp.80-86, 1991-04-25 (Released:2009-09-03)

参考文献数

18

被引用文献数

1 1

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Tuberothalamic artery領域の右視床梗塞を来した結核性髄膜炎の32歳男性例を報告した.発熱と頭痛で発症し, 経過中に失見当識, 了解不良や傾眠状態が出現した.CTではtuberothalamic artery領域の右視床に造影効果のない梗塞巣と考えられる低吸収域を認め, これが失見当識などの原因と考えられた.脳底槽は等吸収域を呈し著明な造影効果を呈した.MRIでは脳底部の血管はflow void phenomenonのため低信号域を呈したが, 脳底槽はT1強調画像で等信号域, T2強調画像では髄液より低い高信号域を呈し, 著明な造影効果を呈し, これがgranulomatous basal arachnoiditisの部位を示していると考えられた.結核性髄膜炎で急に意識障害や精神症状を来した場合には脳梗塞の合併を考慮する必要がある.

著者

大谷 智子 永井 淳一 横澤 一彦

出版者

一般社団法人電子情報通信学会

雑誌

電子情報通信学会技術研究報告. HIP, ヒューマン情報処理

巻号頁・発行日

vol.108, no.27, pp.53-54, 2008-05-12

参考文献数

3

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The purpose of this study is to examine the relation between focal attention and color feature processing. Previous studies have shown that unattended objects could be detected more efficiently when the attended and the unattended objects are common in color feature. In a experiment, subjects were required to identify the color of a peripheral blob as well as the value and color of a digit in the focal attention. The spatial distribution of activation should be decrease with the distance from the focus of attention centered on the attended object. However, the distribution might be decrease with the distance from the fixation point. The dual-task experiment could be conducted to examine these possibilities.