60 0 0 0 OA 5.CONSORT声明

著者
津谷 喜一郎
出版者
一般社団法人 日本臨床薬理学会
雑誌
臨床薬理 (ISSN:03881601)
巻号頁・発行日
vol.40, no.3, pp.105-110, 2009 (Released:2009-08-12)
参考文献数
7
著者
湯川 慶子 石川 ひろの 山崎 喜比古 津谷 喜一郎 木内 貴弘
出版者
日本健康教育学会
雑誌
日本健康教育学会誌 (ISSN:13402560)
巻号頁・発行日
vol.23, no.1, pp.16-26, 2015 (Released:2015-02-27)
参考文献数
32

目的:慢性疾患患者の代替医療による副作用への対処行動や主治医とのコミュニケーションとへルスリテラシーとの関連を明らかにすることを目的とした.方法:2011年5月から7月に,全国の患者会の慢性疾患患者920名に自記式質問紙を用いた横断研究を行った.603通を回収し欠損が多いものを除いた570通のうち(有効回収率62.0%),代替医療の利用経験を持つ428名を対象とした.副作用経験の有無(副作用の経験あり群・経験なし群),副作用時の対処(利用中止群・利用継続群),主治医への副作用の症状と療法の報告(主治医への報告あり群・報告なし群)別のへルスリテラシーについて対応のないt検定を行った.さらに,属性とヘルスリテラシーを説明変数,利用中止,主治医への報告ありを目的変数とした多重ロジスティック回帰分析を行った.結果:428名中88名(20.6%)が副作用を経験していた.そのうち45.9%が利用を継続し,61.6%は主治医に副作用の症状と療法を報告していなかった.利用中止群が利用継続群よりも,報告あり群が報告なし群よりもヘルスリテラシーが高かった.多変量解析でも,ヘルスリテラシーと利用中止か継続かとの関連(OR=2.75,95%CI 1.06-7.10),主治医への報告の有無との関連(OR=2.59,95%CI 1.01-6.65)が認められた.結論:へルスリテラシーは,代替医療による副作用への適切な対処,主治医への報告など,代替医療の安全な利用に重要である.
著者
矢船 明史 津谷 喜一郎
出版者
日本臨床薬理学会
雑誌
臨床薬理 (ISSN:03881601)
巻号頁・発行日
vol.27, no.3, pp.635-645, 1996-09-30 (Released:2010-06-28)
参考文献数
55
被引用文献数
4 7 2

There has been an increasing number of clinical reports in the West to suggest that hepatotoxic reactions can be induced by herbal preparations including skullcap of Scutellaria species. In Japan, the root of Scutellaria baicalensis (Scutellariae Radix) is used under the name of Ogon, which is included in many kinds of Kampo formulations, such as Sho-saiko-to widely used for treating hepatic disorders. Reviewing the Information on Adverse Reactions to Drugs published by the Ministry of Health and Welfare of Japan, we found 22 cases of liver and biliary system reactions caused by Kampo formulations from 1989 through 1993, and in 20 of the cases, six types of Kampo formulations including Ogon were suspected as the cause of the reactions. In two clinical reports of pulmonary damage due to Sho-saiko-to, Lymphocyte Stimulation Test indicated that Ogon was the causative factor for the damage. Although there have been no reports to indicate that Ogon can actually cause liver damage, the results of our review strongly suggest the necessity for surveillance of the possibility of hepatotoxic reactions caused by Ogon.
著者
津谷喜一郎
雑誌
Therapeutic Research
巻号頁・発行日
vol.24, pp.1415-1422, 2003
被引用文献数
4
著者
松本 佳代子 福島 紀子 小林 静子 津谷 喜一郎
出版者
一般社団法人 日本薬剤疫学会
雑誌
薬剤疫学 (ISSN:13420445)
巻号頁・発行日
vol.4, no.1, pp.47-57, 1999-05-31 (Released:2011-02-28)
参考文献数
14
被引用文献数
1 1

Objectives : High and medium-dose combination hormone agents have long been used in their off-label use as oral contraceptives. Oral contraceptives (the low-dose pill) are expected to be approved by the standing committee of the Central Pharmaceutical Affairs Council in June 1999, and are expected to be on the market by autumn, available to anyone bearing a doctor's prescription. A survey was conducted of pharmacy students to determine their acceptance and their perceptions of oral contraceptives (the low-dose pill). The results are discussed along with ways of dealing with the scientific information on the possible soon to be approved oral contraceptives (the low-dose pill), and some proposals are made for the future.Methods : The survey was conducted by distributing questionnaire sheets to female pharmacy college students in September 1996. Of the 670 subjects, 98 responded positively to the use of oral contraceptives (the positive group), while 572 preferred not to use them (the negative group). The two groups were compared and the data was analyzed. Mantel-Haenszel test was used to evaluate demographic and background data, their views on using oral contraceptives (the low-dose pill) and ways of obtaining necessary information.Results : In the responses to the questions on how the subjects feel about oral contraceptives (the low-dose pill), the positive group gave these reasons more frequently than those in the negative group : simple to use (p<0.001), a method with a high contraceptive rate (p<0.001), a means of contraception controlled by the woman (p<0.001). On the other hand, the reasons given more frequently by the negative group : feeling concerned about adverse drug reactions (p<0.001), a method allowing sexually transmitted diseases to propagate (p=0.009), a method increasing the burden on the woman (p<0.001).In terms of the subjects' knowledge of oral contraceptives (the low-dose pill), although there has been some improvement observed during their four-year college life, they did not seen to understand accurate information.Conclusion : The surveyed subjects had not understood accurate information, and this lack of knowledge may have formed their biased views on oral contraceptives (the low-dose pill). Given such results, it is anticipated that such misconceptions may affect their own decision-making in their use of the drug, and that it would cause inefficiency in providing future users with accurate information when these students become pharmacists. In the near future, there is expected to be a deluge of information concerning the low-dose pill. It is clearly necessary in pharmaceutical education to provide proper training of pharmacy students for self-education so as to increase efficiency when considering and evaluating information.
著者
津谷喜一郎著
出版者
津谷喜一郎
巻号頁・発行日
2003