著者

ローゼンバーグ ベンジャミン・E 永井 善之

出版者

金沢大学人間社会研究域法学系

雑誌

金沢法学 (ISSN:0451324X)

巻号頁・発行日

vol.54, no.2, pp.189-244, 2012-02

著者

edited by Richard J.A. Talbert in collaboration with Roger S. Bagnall ... [et al.] and map editors Mary E. Downs M. Joann McDaniel cartographic managers Janet E. Kelly Jeannine M. Schonta David F. Stong

出版者

Princeton University Press

巻号頁・発行日

2000

著者

selected and translated from the Arabic sources by Francesco Gabrieli translated from the Italian by E.J. Costello

出版者

University of California Press

巻号頁・発行日

1969

著者

Hayao Ozaki Takashi Abe Alan E. Mikesky Akihiro Sakamoto Shuichi Machida Hisashi Naito

出版者

一般社団法人日本体力医学会

雑誌

The Journal of Physical Fitness and Sports Medicine (ISSN:21868131)

巻号頁・発行日

vol.4, no.1, pp.43-51, 2015-03-25 (Released:2015-03-23)

参考文献数

69

被引用文献数

2 13

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This paper reviews the existing literature about muscle hypertrophy resulting from various types of training to document the significance of mechanical and metabolic stresses, and to challenge the conventional ideas of achieving hypertrophy that exclusively rely on high-load resistance training. Low-load resistance training can induce comparable hypertrophy to that of high-load resistance training when each bout or set is performed until lifting failure. This is attributable to the greater exercise volume and metabolic stress achieved with low-load exercise at lifting failure, which, however, results in a prolonged exercise bout. Endurance exercises (walking and cycling) at moderate intensity are also capable of eliciting muscle hypertrophy, but at much slower rates (months rather than weeks) in limited muscle or age groups. Blood flow restriction (BFR) in working muscles, however, accelerates the development of metabolic fatigue, alleviating the time consuming issue associated with low-load or endurance training. These alternative training methods, however, cannot completely replace conventional high-load resistance training, which provides superior strength gain as well as performance improvement even for trained individuals. The alternative approaches, therefore, may be considered for those who are less enthusiastic or under certain medical conditions, or who have limited or no access to proper equipment. However, people should be aware that low-load resistance training or endurance training entails substantial effort and/or discomfort at lifting failure or with BFR. Understanding the advantages and disadvantages of each method will help in assigning the most suitable training program for each client’s goals and needs.

著者

Kazuomi Kario Deepak L. Bhatt David E. Kandzari Sandeep Brar John M. Flack Colleen Gilbert Suzanne Oparil Mark Robbins Raymond R. Townsend George Bakris

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-16-0035, (Released:2016-04-26)

参考文献数

42

被引用文献数

7 56

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Background:Obstructive sleep apnea (OSA) is associated with activation of the sympathetic nervous system, and patients with this condition often experience elevated blood pressure (BP), increased BP variability, and nocturnal BP surges.Methods and Results:The SYMPLICITY HTN-3 trial was a large prospective, randomized, blinded, sham-controlled trial of renal denervation for treatment of uncontrolled, apparently treatment-resistant hypertension. In a post hoc analysis, we examined the effect of renal denervation vs. sham control on office and ambulatory (including nocturnal) systolic BP in patients with and without OSA. 26% (94/364) of renal denervation subjects and 32% (54/171) of sham control subjects had OSA. Baseline office and nighttime systolic BP values were similar in both arms, including in subjects with and without OSA. Compared with sham control, renal denervation reduced the 6-month office systolic BP in subjects with (−17.0±22.4 vs. −6.3±26.1 mmHg, P=0.01) but not in subjects without OSA (−14.7±24.5 vs. −13.4±26.4 mmHg, P=0.64), P=0.07 for the interaction between treatment arm and OSA status. In those with sleep apnea, renal denervation was also associated with a reduction in maximum (−4.8±21.8 vs. 4.5±24.6 mmHg, P=0.03) and average peak (−5.6±20.4 vs. 3.2±22.4 mmHg, P=0.02) nighttime systolic BP.Conclusions:OSA subjects appeared to be responsive to renal denervation therapy. However, this hypothesis requires prospective testing.

著者

Özge TURNA YILMAZ TSF TOYDEMIR İ KIRŞAN B DOKUZEYLUL Z GUNAY E KARACAM

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.14-0112, (Released:2014-09-20)

被引用文献数

5

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The analgesic effect of wound infiltration with bupivacaine was evaluated in cats undergoing bilateral mastectomy. Twenty-one female cats with mammary gland tumors were anesthetized with propofol and oxygen-isoflurane anesthesia following premedication with atropine. In the trial group (Group I; n=11), 30 ml of saline containing 2 mg/kg of bupivacaine was infiltrated topically into the surgical wound right after removal of the mammary glands, whereas only saline solution was infiltrated in the control group (Group II; n=10). At the same time, carprofen (4 mg/kg) was also administered subcutaneously in both groups. Behavioral signs of pain were monitored during the recovery period after general anaesthesia. In order to examine the behavioral changes associated with acute pain, a questionnaire was prepared and given to the owners to be completed 4 hr and then 10 hr after the operation. According to the owners’ anwers to the questionnaire, a pain score was specified using a “numerical rating scale” for each cat. Although some cats showed mild to moderate pain, the pain score recorded at 4 hr after the operation was significantly lower in Group I (P<0.001). No significant difference was found at 10 hr after the operation between the groups. The incidence of vocalization, aggression and convulsion within 2 hr after the operation were also lower in Group I. In conclusion, wound infiltration with bupivacaine before incisional closure provided reliable analgesia at least 4 hr after bilateral radical mastectomy in cats.

著者

Tonegawa S Kasahara S Fukuda T Sugimoto K Yasuda N Tsuruhara Y Watanabe D Mizukami Y Haga Y Matsuda T D Yamamoto E Onuki Y Ikeda H Matsuda Y Shibauchi T

出版者

Nature Publishing Group

雑誌

Nature communications (ISSN:20411723)

巻号頁・発行日

vol.5, 2014-06-19

被引用文献数

57

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直接観測された物質物理学の謎「隠れた秩序」. 京都大学プレスリリース. 2014-06-19.

著者

Forster Douglas E.

出版者

日本女子大学

雑誌

日本女子大学紀要. 文学部 (ISSN:02883031)

巻号頁・発行日

vol.56, pp.129-105, 2007-03-20

著者

LEAKE B. E.

雑誌

Canad. Mineral.

巻号頁・発行日

vol.35, pp.216-246, 1997

被引用文献数

26

著者

Rocío de la Vega Irina A. Heinisuo Alicia E. López-Martínez Elena R. Serrano-Ibáñez Gema T. Ruíz-Párraga Carmen Ramírez-Maestre Rosa Esteve

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.35, no.12, pp.768-776, 2023 (Released:2023-12-01)

参考文献数

26

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[Purpose] Non-invasive and drug-free interventions for pain are being developed. One of them is ANF (which stands for “Amino Neuro Frequency”) Therapy®, which consists in the application of carbonized metal devices on a patient’s skin. We aimed to: 1) test perceived changes in pain intensity after ANF application, 2) record frequency and severity of side effects, 3) assess clinician and patient satisfaction, 4) explore effects on swelling and range of motion (ROM). [Participants and Methods] In this real-world multisite observational study, N=113 physical therapists in 45 countries, applied ANF to N=1,054 patients (Mage=45.2, 56.2% female) with pain complaints. Demographic data, pain intensity (NRS-11), effects of ANF on swelling and ROM, clinician and patient satisfaction and side effects were collected. [Results] Main pain locations were: low back (14.9%), knee (12.4%), neck (10%), and shoulder (9.6%). Pre-treatment pain intensity was high (Mean=7.6, SD=1.9). It significantly decreased post-treatment (Mean=3.1, SD=2.0), t(1053)=7.25, with a large effect size (Cohen’s d=2.2). Swelling decreased and ROM increased. Average satisfaction with ANF was 92/100. Patients often experienced mild side effects (42.3%): dry mouth, headache and fatigue. [Conclusion] Results show large effect sizes, high satisfaction, and mild and short-term side effects. This is very promising but should be interpreted with caution considering the study limitations.

著者

Shumpei Mori Diane E. Spicer Robert H. Anderson

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.80, no.1, pp.24-33, 2015-12-25 (Released:2015-12-25)

参考文献数

48

被引用文献数

2 51

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An understanding of the complexity of cardiac anatomy is required by all who seek, in the setting of cardiac disease, to interpret the images confronting them. Although the mysteries of cardiac structure have been extensively addressed, significant gaps continue to exist between the descriptions provided by morphologists and by those working in the clinical setting. In part, this reflects the limitations in providing 3D visualization of such a complicated organ. Current 3D imaging technology now permits visualization of the cardiac components using datasets obtained in the living individual. These advances, furthermore, demonstrate the anatomy in the setting of the heart as imaged within the thorax. It has been failure to describe the heart as it lies within the thorax that remains a major deficiency of many morphologists relying on the dissecting room to provide the gold standard. Describing the heart in attitudinally appropriate fashion, a basic rule of clinical anatomy, creates the necessary bridges between anatomists and clinicians. The rapid progression of cardiac interventional techniques, furthermore, emphasizes the need to revisit cardiac anatomy using a multidisciplinary approach. In this review, therefore, we illustrate the advantages of an attitudinally correct approach to cardiac anatomy. We then focus on the morphology of the arterial roots, revealing the accuracy that can now be achieved by clinicians using datasets obtained during life. (Circ J 2016; 80: 24–33)

著者

Sahar Y. Al-Okbi Shaimaa E Mohammed Enas S.K. Al-Siedy Naglaa A. Ali

出版者

Japan Oil Chemists' Society

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

vol.69, no.7, pp.771-782, 2020 (Released:2020-07-02)

参考文献数

56

被引用文献数

2 4

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The role of fish oil, primrose oil and their mixture in ameliorating the changes in Alzheimer’s like model was evaluated in rats. Primrose oil and primrose/fish oil mixture fatty acids composition was assessed by gas chromatography. The rat experiment consisted of 5 groups; the first fed on balanced diet as control normal (CN); the other four groups treated with intraperitoneal aluminum lactate and consumed dyslipidemic diet; one group served as control Alzheimer’s like disease (CA) while the other three groups (test groups) received daily oral dose from primrose oil, fish oil and primrose/fish oil mixture separately for 5 weeks. Results showed primrose oil and primrose/ fish oil mixture to contain gamma linolenic acid as 9.15 and 4.3% of total fatty acids, respectively. Eicosapentaenoic and docosahexaenoic were present as 10.9 and 6.5 %, respectively in the oil mixture. Dyslipidemia and increased erythrocyte sedimentation rate (ESR), plasma butyrylcholinesterase (BChE), brain malondialdehyde (MDA) and NO with decrease in plasma magnesium, brain catalase, reduced glutathione, body weight gain and brain weight were demonstrated in CA compared to CN. Brain histopathology and immuno-histochemistry showed neuronal degeneration and neurofibrillary tangles with elevated myeloperoxidase and nuclear factor-kappa B in CA compared to CN. The tested oils demonstrated neuro-protection reflected in the variable significant improvement of biochemical parameters, immuno-histochemistry and brain histopathology. Primrose/fish oil mixture was superior in reducing ESR, brain MDA, plasma activity of BChE and brain histopathological changes along with elevating plasma magnesium. Primrose/fish oil mixture and fish oil were more promising in improving plasma high density lipoprotein cholesterol (HDL-C) than primrose. Fish oil was the most efficient in improving plasma total cholesterol (T-C), low density lipoprotein cholesterol and T-C /HDL-C. Primrose/fish oil mixture and primrose oil were superior in elevating brain catalase compared to fish oil. Other parameters were equally improved by the different oil treatments. Primrose oil, fish oil and their mixture reduced the progression of Alzheimer’s disease in rats with superiority to primrose/fish oil mixture.

著者

Anurag Sahoo Mohamad Abdalkader Hiroshi Yamagami Xiaochuan Huo Dapeng Sun Baixue Jia Charlotte S. Weyland Francesco Diana Artem Kaliaev Piers Klein Jenny Bui Sami Al Kasab Adam de Havenon Osama O. Zaidat Wenjie Zi Qingwu Yang Patrik Michel James E. Siegler Shadi Yaghi Wei Hu Thanh N. Nguyen

出版者

The Japanese Society for Neuroendovascular Therapy

雑誌

Journal of Neuroendovascular Therapy (ISSN:18824072)

巻号頁・発行日

pp.ra.2023-0047, (Released:2023-08-29)

参考文献数

92

被引用文献数

4

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Endovascular therapy (EVT) has revolutionized the treatment of acute ischemic stroke. In the past few years, endovascular treatment indications have expanded to include patients being treated in the extended window, with large ischemic core infarction, basilar artery occlusion (BAO) thrombectomy, as demonstrated by several randomized clinical trials. Intravenous thrombolysis (IVT) bridging to mechanical thrombectomy has also been studied via several randomized clinical trials, with the overall results indicating that IVT should not be skipped in patients who are candidates for both IVT and EVT. Simplification of neuroimaging protocols in the extended window to permit non-contrast CT, CTA collaterals have also expanded access to mechanical thrombectomy, particularly in regions across the world where access to advanced imaging may not be available. Ongoing study of areas to develop include rescue stenting in patients with failed thrombectomy, medium vessel occlusion thrombectomy, and carotid tandem occlusions. In this narrative review, we summarize recent trials and key data in the treatment of patients with large ischemic core infarct, simplification of neuroimaging protocols for the treatment of patients presenting in the late window, bridging thrombolysis, and BAO EVT evidence. We also summarize areas of ongoing study including medium and distal vessel occlusion.

著者

Amy K. PARKIN Amy J. ZADOW Rachael E. POTTER Ali AFSHARIAN Maureen F. DOLLARD Silvia PIGNATA Arnold B. BAKKER Kurt LUSHINGTON

出版者

National Institute of Occupational Safety and Health

雑誌

Industrial Health (ISSN:00198366)

巻号頁・発行日

pp.2022-0078, (Released:2022-08-08)

被引用文献数

4

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Due to the COVID-19 pandemic, the number of employees in flexible work from home has increased markedly along with a reliance on information communication technologies. This study investigated the role of an organisational factor, psychosocial safety climate (PSC; the climate for worker psychological health and safety), as an antecedent of these new kinds of demands (specifically work from home digital job demands) and their effect on work-life conflict. Data were gathered via an online survey of 2,191 employees from 37 Australian universities. Multilevel modelling showed that university level PSC to demands, y=−0.09, SE=0.03, p<0.01, and demands to work-life conflict, y=0.51, SE=0.19, p<0.05, relationships were significant. Supporting the antecedent theory, university level PSC was significantly indirectly related to work-life conflict via demands (LL −0.10 UL −0.01). Against expectations PSC did not moderate the demand to work-life conflict relationship. The results imply that targeting PSC could help prevent work from home digital job demands, and therefore, work-life conflict. Further research is needed on the role of digital job resources as flexible and hybrid work takes hold post COVID.

著者

Barrios Arroyave A. Freddy Rodríguez Velásquez O. Javier Prieto Bohórquez E. Signed Grisales E. Carlos Correa Herrera C. Sandra Jattin Balcázar J. Jairo Soracipa Muñoz Ribka Ruiz Morales J. Jhon

出版者

The Japanese Society of Strategies for Cancer Research and Therapy

雑誌

Annals of Cancer Research and Therapy (ISSN:13446835)

巻号頁・発行日

vol.31, no.1, pp.7-12, 2023-02-14 (Released:2023-02-14)

参考文献数

26

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Introduction: fractal geometry has been implemented to study natures’ irregular objects with diverse applications in medicine, from characterizations of human structures such as the division of bronchial or arterial trees to the diagnosis of abnormal cells, as it has been evidenced in the study of neoplasms. In this investigation, a characterization of the degree of irregularity of histologic samples of normal and thyroid gland neoplasms was developed in the context of fractal and Euclidean geometry.Methods: photographs of normal and neoplastic thyroid histologic samples obtained as surgical pieces were processed by a software that allows to delimit the borders of cellular structures. Then, grids of 5 and 10 pixels were superimposed over the images in order to measure their surfaces and occupation spaces through the Box-Counting method.Results: For nucleus measures values between 14 to 34 in the 5 pixels grid and values between 7 to 16 in the 10 pixels grid suggest normality.Conclusions: The surface of the nucleus and the cytoplasm measured by grids of 5 and 10 pixels, allow to carry out a more objective characterizations of both normal and abnormal thyroid cells.

著者

W.A.シューハート著 W.E.デミング編 坂元平八監訳

出版者

岩波書店

巻号頁・発行日

1960

著者

Ruth E. Propper

出版者

SOCIETY FOR FREE RADICAL RESEARCH JAPAN

雑誌

Journal of Clinical Biochemistry and Nutrition (ISSN:09120009)

巻号頁・発行日

vol.68, no.1, pp.3, 2021 (Released:2021-01-01)

参考文献数

5

被引用文献数

4 6

著者

Samira R. Aili Phillip Lo Jeanette E. Villanueva Yashutosh Joshi Sam Emmanuel Peter S. Macdonald

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.86, no.1, pp.14-22, 2021-12-24 (Released:2021-12-24)

参考文献数

43

被引用文献数

1 10

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Background:Frailty is prevalent in patients with heart failure (HF) and associated with increased morbidity and mortality. Hence, there has been increased interest in the reversibility of frailty following treatment with medication or surgery. This systematic review aimed to assess the reversibility of frailty in patients with HF before and after surgical interventions aimed at treating the underlying cause of HF. It also aimed to assess the efficacy of cardiac rehabilitation and prehabilitation in reversing or preventing frailty in patients with HF.Methods and Results:Searches of PubMed, MEDLINE and Academic Search Ultimate identified studies with HF patients undergoing interventions to reverse frailty. Titles, abstracts and full texts were screened for eligibility based on the PRISMA guidelines and using predefined inclusion/exclusion criteria in relation to participants, intervention, control, outcome and study design. In total, 14 studies were included: 3 assessed the effect of surgery, 7 assessed the effect of rehabilitation programs, 2 assessed the effect of a prehabilitation program and 2 assessed the effect of program interruptions on HF patients.Conclusions:Overall, it was found that frailty is at least partially reversible and potentially preventable in patients with HF. Interruption of rehabilitation programs resulted in deterioration of the frailty status. Future research should focus on the role of prehabilitation in mitigating frailty prior to surgical intervention.

著者

Abeer E. DIEF Doaa M. SAMY Fatma I. DOWEDAR

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.61, no.1, pp.1-7, 2015 (Released:2015-05-21)

参考文献数

38

被引用文献数

18 23

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Chronic stress affects brain areas involved in learning and emotional responses through modulation of neurotropic factors or neurotransmitters. Therefore, we investigated the role of exercise and thiamine supplementation on spatial memory and on brain-derived neurotrophic factor (BDNF) and acetylcholine (Ach) content in the hippocampus of the stressed animals. Male Wistar rats were randomly assigned to 4 groups (8 rats/group): control group; stress group; swimming and stress group; and thiamine and stress group. All animals were assessed by a T maze for spatial memory or open field test for locomotion and anxiety. BDNF and Ach were estimated in the hippocampus. Chronic immobilization stress resulted in a significant decrease in BDNF and Ach levels in the hippocampus and impairment in spatial memory functions and decreased basal activity. However, either swimming training or thiamine intake for 30 d was proved to induce a significant increase both in BDNF and Ach in conjunction with improved performance in the T maze, marked anxiolytic effect and enhanced ambulation in the open field test, as compared to the stress group. Interestingly, swimming-exercised rats showed significantly higher levels of BDNF versus thiamine-receiving rats, while thiamine-receiving rats showed higher locomotor activity and less freezing behavior in the open field test compared to the swimming group. It was concluded that decreased BDNF and Ach after stress exposure could be a mechanism for the deleterious actions of stress on memory function; swimming exercise or vitamin B1 supplementation for 30 d was a protective tool to improve coping with chronic stress by modulating BDNF and Ach content along with enhancement of memory functions and motor activities.

著者

Karen E. JOHNSON Li-Chen LIN Shalonda Estelle Brazzell HORTON Ana TODD Nancy GUILLET Stephanie MORGAN

出版者

Disaster Nursing Group

雑誌

Health Emergency and Disaster Nursing (ISSN:21882053)

巻号頁・発行日

vol.9, no.1, pp.23-30, 2022-03-25 (Released:2022-03-25)

参考文献数

37

被引用文献数

2

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Aim: This paper examines nurse-led interdisciplinary efforts to address COVID-19 vaccine inequities in Texas, United States (US) through the founding of a two-pronged community-based vaccination program, VAMOS-VaxNOW.Methods: Using state/federal reports and guidelines, local/national news sources, and volunteers’ voices, we frame our efforts within the sociopolitical and historical contexts that contributed to the need for VAMOS-VaxNOW.Results: Like most states, Texas distributed most of its vaccine supply to mass hubs that could efficiently serve large amounts of people. Nursing faculty at The University of Texas at Austin quickly recognized the need to expend effort into mobile clinics to reach populations who were likely to face barriers to accessing mass hubs (e.g., language barriers, transportation/mobility limitations, institutional mistrust). Leveraging long-standing relationships with community partners, we launched our first mobile vaccine clinic (VAMOS) with a historically Black church in March, 2021. From there we partnered with other community organizations serving populations experiencing vaccine inequities (e.g., Spanish-speaking churches, apartment complexes) to host mobile clinics. We also began a home visit program (VaxNow) for those facing mobility challenges or other barriers to accessing mass hubs. Our “hub-and-spoke” model was the first of its kind in our community and served as a model for others launching similar efforts.Conclusions: VAMOS-VaxNOW highlights the importance of nurse-led, interdisciplinary disaster response. Early mobilization planning guided by a deep understanding of how present-day and historical inequities shape disaster outcomes, thoughtful leaders collaborating with community partners, compassionate volunteers, and building trust were key factors in leading the successful operation.