著者
泉 喜和子 下田 恒久 下田 哲也 香川 豊宏 池邉 哲郎 大関 悟
出版者
公益社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.56, no.4, pp.261-265, 2010-04-20 (Released:2013-10-19)
参考文献数
13
被引用文献数
2 2

This report describes the feasibility of posterior-superior repositioning of the maxilla by Le Fort Ⅰ osteotomy with a pterygoid process fracture, while preserving the descending palatine artery. We examined movement accuracy and stability in 3 patients in whom maxillary protrusion with vertical maxillary excess was treated by moving the maxilla backward more than 4 mm. The postsurgical positions of the maxilla were more posterior than the presurgical expectations, but the differences were within 1 mm. Cephalometric analysis revealed that the differences in each measurement between immediately and one year after surgery were within 1 degree. Without mandibular osteotomy, maxillary protrusion can be satisfactorily treated with Le Fort Ⅰ osteotomy alone.
著者
田中 宏和 宮澤 英樹 林 清永 峯村 俊一 倉科 憲治 栗田 浩
出版者
公益社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.60, no.10, pp.581-586, 2014-10-20 (Released:2015-07-17)
参考文献数
22
被引用文献数
1 2

The number of patients attacked by bears has been rising recently because the opportunity to encounter wild bears has increased. Bear attacks usually focus on the head and neck areas, and the attack sometimes causes fatal injuries.We report two cases of multiple facial lacerations and mandibular bone comminuted fractures caused by a bear attack.A 70-year-old man and a 60-year-old man were attacked by a black bear while mushroom picking. They sustained mandibular bone comminuted fractures with deep lacerations of the face. They were brought to our emergency room. Their lives were saved by immediate surgery. In addition, it was necessary to provide preventative measures against infection.
著者
梯 裕恵 白石 剛士 河井 洋祐 南里 篤太郎 野田 さわこ 池田 久住 朝比奈 泉
出版者
公益社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.60, no.12, pp.672-676, 2014-12-20 (Released:2015-08-25)
参考文献数
18
被引用文献数
2 4

Mucous-retention cysts such as mucocele and ranula are caused by mucus extravasation due to rupture of ducts of the major and minor salivary glands. While several techniques have been used to treat retention cysts, micro-marsupialization is a relatively new, less invasive treatment modality. We describe this new method, which is not popular in Japan, and report the clinical outcomes of 13 cases of mucoceles and ranulas treated with this technique.We evaluated the therapeutic value of micro-marsupialization on the basis of cure rate and events such as infection and recurrence. As a result, ten cases (76.9%) showed complete remission of the lesions and three cases including one case of infection required retreatment.Micro-marsupialization seems to be a simple, minimally invasive and effective modality, and is well tolerated by patients. We accordingly suggest that it could be a primary treatment of choice for mucous retention cysts.
著者
山本 大介 目瀬 浩
出版者
公益社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.64, no.5, pp.274-278, 2018-05-20 (Released:2018-07-20)
参考文献数
18

Case reports describing mandibular fractures associated with external auditory canal fractures without condylar fractures are extremely rare. We report a case of mandibular and external auditory canal (EAC) fractures. A 56-year old man was referred to our department because of pain on opening and closing of the jaw. He had hypertension, diabetes mellitus, sleep apnea syndrome, and familial myoclonus epilepsy. In January 2014, he bruised his chin and precordial region when he fell down because of orthostatic hypotension. He was transported to a nearby general hospital and underwent treatment for a laceration on the chin. He was introduced to our department to receive treatment for hemorrhage from both the EAC fracture and mandibular fracture. Local examination showed disturbed mouth opening due to jaw pain and bloody discharge from both auditory canals. There was also a laceration on the chin. Computed tomography (CT) disclosed a fracture line at the mandibular symphysis and both EACs, but the auditory ossicles were not separated. The patient was treated by packing both auditory canals in consultation with the Department of Otolaryngology. We performed open reduction and internal fixation (ORIF) surgery with the patient under general anesthesia, and intermaxillary fixation (IMF) was secured for 1 week. The patient was followed up for 1 year, and healing was satisfactory with no subsequent stenosis of the auditory canal.
著者
浅香 卓哉 坂田 健一郎 竹川 英輝 羽藤 裕之 鎌口 真由美 大賀 則孝 佐藤 淳 山崎 裕 北川 善政
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.65, no.8, pp.500-506, 2019-08-20 (Released:2019-10-21)
参考文献数
28

Glossodynia is defined as a burning sensation on the tongue without any systemic or local cause. Although its pathophysiology remains unclear, it has been associated with neuropathic, nociceptive, and psychogenic pains. In Japan, difficulties are encountered in the treatment of glossodynia as prescribed medications are not covered by health insurance. Recently, a traditional Chinese medicine treatment (kampo), rikko-san (TJ-110), has been suggested to be useful for glossodynia. The objective of this retrospective study was to evaluate the efficacy of rikko-san gargling in patients with glossodynia. In total, 221 patients with glossodynia who were treated by rikko-san gargling between 2012 and 2018 were examined. Of these, 90 patients (seven men, 83 women; mean age, 67 years) who were treated by gargling with rikko-san dissolved in water for >1 month and no other medications were included. Tongue pain was assessed using a visual analog scale (VAS). Improvement was defined as at least a 50% reduction in the VAS score after treatment compared with that before treatment. The associations between the efficacy of rikko-san gargling and factors such as age, disease duration, pain area, and psychiatric disorders were evaluated. Improvement was noted in 60% of the patients (54/90) ; the mean administration period to the end of treatment in the improvement group was approximately 5 months. There was no significant correlation between the aforementioned factors and the efficacy of rikko-san gargling. Treatment in 41 patients was completed with rikko-san gargling alone, whereas 40 patients required additional treatment such as another kampo medicine or ethyl loflazepate. No side effect was observed in any patient, although stomatitis was noted in one excluded case. The mechanism underlying rikko-san’s delivery pathway is distinct from that of selective serotonin reuptake inhibitors, benzodiazepines, and nonsteroidal anti-inflammatory drugs. We speculated that saishin (Asiasarum root), one of the major components of rikko-san, may reduce peripheral stimulation to the tongue surface through its anesthetic effect. In addition, the transmucosal actions of other components in rikko-san may influence various receptor-related neuropathic pains. In conclusion, rikko-san gargling is efficacious and safe for the treatment of glossodynia.
著者
齊藤 昌樹 畑中 隆志 川口 拓郎 久馬 孝仁 長嶺 健二郎 澤木 佳弘
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.61, no.12, pp.667-672, 2015-12-20 (Released:2016-03-14)
参考文献数
34
被引用文献数
1 5

Recently, methotrexate-associated lymphoproliferative disorders (MTX-LPD) in patients with rheumatoid arthritis (RA) have frequently been reported as a lymphoproliferative disorder developing in immunosuppressed patients. Many reports have indicated a relation between MTX-LPD and Epstein-Barr virus (EBV). We report 4 cases of EBV-positive MTX-LPD arising in the oral cavity. After consulting a hematologist, methotrexate (MTX) was discontinued in three patients, and one patient moved to another medical facility. Three lesions regressed after MTX withdrawal. However, one patient who resumed treatment with MTX had a relapse of LPD. A literature search on MTX-LPD in the oral cavity revealed a high positive rate of EBV, a good response to MTX withdrawal, a higher prevalence in women, and a high frequency of maxillary gum involvement.
著者
岩田 英治 古土井 春吾 鰐渕 聡 岸本 恵実 明石 昌也 古森 孝英
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.64, no.2, pp.83-87, 2018-02-20 (Released:2018-04-20)
参考文献数
17

Osteonecrosis of the jaw is one of the problematic side effects observed during administration of angiogenesis inhibitors in patients receiving treatment for cancer. We report a case of osteonecrosis of the jaw in a patient receiving sunitinib. The patient was a 72-year-old man who was referred to our hospital because of exposed bone and contact pain of the tongue. After the clinical diagnosis of osteonecrosis of the jaw, observation and irrigation of the exposed bone were frequently performed. Four months later, the lesion healed. After 1 year, exposed bone was found in other sites ; however, it disappeared a month later. The present case suggests that the use of sunitinib can be associated with osteonecrosis of the jaw and indicates that invasive dental treatment and the status of the main disease should be considered when prescribing sunitinib, as is done when prescribing bisphosphonates or denosumab.
著者
奥田 克爾
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.56, no.4, pp.231-239, 2010-04-20 (Released:2013-10-19)
参考文献数
29

Oral biofilm-forming bacteria consist of a dense bacterial mass tightly adhering to the surface of the oral cavity. The characteristics of dental biofilm are resistant against not only host defense mechanisms but also various antimicrobial agents. The predominant bacteria forming biofilm result in persistent infection. The proteolytic enzymes, exotoxins, endotoxins, and HSPs of these bacteria play a significant role in the development of oral infectious disease and affect systemic condition.We detected DNA and antigen of Treponema denticola in atherosclerotic lesions, and also found that the 16S rRNAs of Porphyromonas gingivalis, Aggregatibacter (formally Actinobacillus) actinomycetemcomitans,Tannerella forsythia, T. denticola, and Campylobacter rectus in samples of stenotic coronary arterial plaque. We showed the invasive activity of these bacteria into human vein endothelial cells. Increasing evidence has linked the dental biofilm with respiratory infectious diseases such as aspiration pneumonia in elderly persons. We investigated the effects of oral health care for elderly persons requiring nursing care on prevention of influenza infection.In the oral care group, colony-forming cell number, neuraminidase and trypsin-like protease activities in saliva decreased. It was found that one of 98 patients was diagnosed with influenza; whereas, in the non-oral care group,nine of 92 patients were diagnosed with influenza. The finding indicates that oral hygiene is one of the effective strategies to prevent influenza infection. Periodontal surrounding cells such as macrophage possessing TLRs and CD14 that are endotoxin binding protein. Carrying endotoxin with macrophage to various tissues releases inflammatory cytokines such as TNF-αand IL-1 that produce resistance to insulin sensitivity and cause obesity and diabetes. An attempt to discover new things by studying the past through scrutiny of old, there are many evidences on the close relationship between the primary dental biofilm infectious diseases and secondly systemic diseases such as nephritis, dermatitis and arthritis.The author firmly believes that control of oral biofilm-forming infectious diseases by the surgical treatment is an essential strategy and management of such systemic conditions.
著者
清水 正嗣 水城 春美 福山 義邦 松本 有史 河村 哲夫 柳沢 繁孝
出版者
Japanese Society of Oral and Maxillofacial Surgeons
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.37, no.7, pp.1380-1384, 1991-07-20 (Released:2011-07-25)
参考文献数
10

A case with fresh gunshot wound penetrating from the left lateral neck to the mouth angle, which was caused by pistol shooting during a conflict between gangs, was reported and discussed by us.The patient, a 41-year-old male, was shot probably with a 38-caliber revolver from behind. Its entrance was on the left rear of the neck, and the exit hole at the left mouth angle. The route through the body: the bullet passed inside of the mandible, where it caused a crashing fracture of the body in the molar region while breaking the lower prosthesis. But, he was very lucky that the important blood vessels and nerve bundles were not injured, although the route was very close to them. He was transported to our Dept. that same day and operated on under general anesthesia for removing foreign bodies, uniting and fixing the jaw fracture, and also for reconstructing the mouth angle, while we sanitized the wound and sutured the soft tissues at each place. At last, a tracheotomy was performed, to prevent suffocation from postoperative swelling. The progress after the operation was good, and he was discharged three weeks later. After 3 years he is now healthy and in prison.
著者
岩永 譲 古賀 千尋 加来 伸一郎 藤井 智津 岩本 修 楠川 仁悟
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.56, no.2, pp.95-97, 2010-02-20 (Released:2013-10-19)
参考文献数
9

A case of oral mucosal ulcer caused by the inappropriate use of nicotine gum is reported.The patient was a 55-year-old man who was a heavy smoker. He had smoked 60 cigarettes a day for 36 years. He had been using nicotine gum as a "stop-smoking aid" for over 8 months. He was referred to our department because of an unhealed undermining ulcer at the mucogingival junction of the lower right anterior teeth. On exfoliative cytology, there were no atypical cells in a specimen of the ulcer. Therefore, we recommended him to stop using nicotine gum, which was inappropriately placed at the buccal vestibule of mouth. The tenderness then gradually improved, and the ulcer healed in the month. Long-term inappropriate use of nicotine gum can cause adverse effects to the oral mucosa.
著者
篠崎 昌一 森山 雅文 林田 淳之介 田中 昭彦 前原 隆 古川 祥子 太田 美穂 今林 佑美 中村 誠司
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.61, no.3, pp.147-153, 2015-03-20 (Released:2015-09-29)
参考文献数
13
被引用文献数
1

Objectives: Cevimeline hydrochloride (CH) and pilocarpine hydrochloride (PH) are recognized as salivation-inducers with a high affinity for M3 muscarinic receptors. However, these drugs have a high frequency of side effects, including digestive symptoms and hyperhidrosis. We compared the effectiveness and side effects of these two drugs before and after a medication change.Materials and Methods: Seventy-six patients with Sjögren's syndrome were divided into the following four groups: 1) CH group, CH was administered for 12 months; 2) PH group, PH was administered for 12 months; 3) CH-PH group, CH was administered for 6 months followed by PH for 6 months; 4) PH-CH group, PH was administered for 6 months followed by CH for 6 months. We measured the salivary flow rate and recorded the subjective symptoms in each group.Results: In each group, stimulated whole saliva (SWS) and unstimulated whole saliva (UWS) significantly increased after 3 months and 6 months, respectively, and subjective symptoms improved after 3 months. The incremental changes in both SWS and UWS did not differ significantly between the groups. The CH and PH groups both had digestive symptoms (32.3% and 32.1%, respectively) and hyperhidrosis (29.0% and 39.3%, respectively). We found no significant difference in salivary flow rate or subjective symptoms after the medication change. However, the frequencies of side effects in the CH-PH and PH-CH groups decreased significantly for both digestive symptoms (9.7% and 10.7%, respectively) and hyperhidrosis (25.8% and 14.3%, respectively).Conclusions: After changing the salivation-inducing drug, there was no significant difference in salivary function or subjective symptoms, while the frequency of side effects markedly decreased. These results suggest that changing the salivation-inducing drug effectively reduces side effects.
著者
新田 哲也 坂元 亮一 平原 成浩 松村 吉晃 中村 康大 後藤 雄一
出版者
公益社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.65, no.9, pp.599-604, 2019-09-20 (Released:2019-11-20)
参考文献数
27
被引用文献数
1 1

The side effects of peroral bisphosphonate may cause mucous membrane disorders and oral exulceration if individuals dissolve the drug inside the oral cavity on oral administration. We experienced two cases in which we strongly suspected mucous ulcurs due to this drug. Finally, the oral exulceration disappeared after providing instructions on correct administration. An 83-year-old woman was referred because of exulceration of the right mandible. She suffered from osteoporosis, thoracic vertebra compression fracture, and dementia, while taking alendronate weekly. The exulceration appeared from the right lower lip to the right mandibular molar gingiva when we absorbed pooled saliva in the right oral cavity when the patient was lying down. We instructed the patient to confirm that the tablet was completely swallowed. The ulcers in the oral cavity completely disappeared 17 days after presentation. A 74-year-old woman with osteoporosis presented because of bleeding and pain in the gingiva of the right mandible. She was taking monthly minodronate while wearing incompatible dentures. Exulceration occurred with peripheral redness ranging from the right buccal mucosa to the right molar gingiva of the mandible and the tongue/floor of her mouth, along with a ventrolateral tongue. We taught her how to swallow minodoronate correctly without dentures, and the ulcers healed 4 weeks later.
著者
宗圓 聰
出版者
公益社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.66, no.2, pp.40-51, 2020-02-20 (Released:2020-04-20)
参考文献数
24

Antiresorptive drugs, such as the bisphosphonates and the RANKL inhibitor denosumab, are currently the most widely used osteoporosis medications. These drugs increase bone mineral density (BMD) and reduce the risk of vertebral, nonvertebral and hip fractures in postmenopausal women with osteoporosis. Recently, anabolic therapy with teriparatide was demonstrated to be superior to the bisphosphonate risedronate in postmenopausal women with vertebral fracture. Treatment with the sclerostin antibody romosozumab increase BMD more profoundly and rapidly than alendronate and is also superior to alendronate in reducing the risk of vertebral and nonvertebral fracture in postmenopausal women with osteoporosis. For patients with severe osteoporosis and high fracture risk, bisphosphonates alone are unlikely to be able to provide long-term protection against fracture and restore BMD. For those patients, sequential treatment, starting with anabolic drug, followed by an antiresorptive, will likely provide better long-term fracture prevention and should be the golden standard of future osteoporosis treatment. The concept of a “drug holiday” applies only to patients taking bisphosphonates because of a transient residual antiresorptive effect after discontinuation due to skeletal retention of drug. For non-bisphosphonates, a drug holiday is not appropriate because BMD declines rapidly after treatment is stopped.
著者
林 誠一
出版者
Japanese Society of Oral and Maxillofacial Surgeons
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.39, no.1, pp.41-46, 1993-01-20 (Released:2011-07-25)
参考文献数
19

To investigate the efficacy of aciclovir for herpetic gingivostomatitis, changes in local lesions and fluctuations in local virus titer were compared between a treated group of patients given oral aciclovir (4 patients, 7 sites, 36 specimens) and a control group of patients not given aciclovir (3 patients, 5 sites, 15 specimens). Specimens were able to be taken from the same site for several days in succession in all patients. The results demonstrated improvement in clinical symptoms in the treated group from day 2 of treatment. Likewise, a tendency towards cure of local symptoms was noted remarkably earlier in the treated group than in the control group. In addition, assessment of the virus titer of specimens taken daily from the same site revealed that the virus was not isolated from local specimens as early as after 1 day of treatment up to 3 days of treatment in the oral aciclovir group. The results indicated that oral aciclovir is therapeutically effective for herpes simplex virus and that the drug should be administered for at least 3 days.
著者
佐々木 研一 正木 日立 三宅 晋 山 満 亀田 恭子 久木元 喜昭 山口 雅庸 柿沢 卓 野間 弘康
出版者
Japanese Society of Oral and Maxillofacial Surgeons
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.32, no.7, pp.1139-1149, 1986-07-20 (Released:2011-07-25)
参考文献数
22
被引用文献数
4 4

Several types of osteotomy have been performed for correction of mandibular prognathism, retrognathia and assymmetry.The injury of the inferior alvolar nerve as a complication were evaluated in 35 patients after the surgery.1. Anesthesia, hypesthesia and paresthesia of the lip and mental area were observed in all of the patients (35 cases) in early stage after the operation.2. 70.8% of the patients who were treated with sagittal splitting osteotomy were recognized as S4 (Highet's standards) within a year.3. The Average of the sensory nerve conduction velocity (S.C.V.) of normal was approximately 60m/sec.Nerve action potential could not be recorded in early stage and gradually returned to normal S.C.V.from 20 weeks after the surgery.4. Complete return of the sensation was recognized within 40 weeks after the operation which mandible were moved less than 10mm.5. There is no difference of return of sensation between circumferencial wiring and bone screw fixation after sagittal splitting osteotomy.
著者
今里 聡
出版者
公益社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.61, no.7, pp.360-362, 2015-07-20 (Released:2015-11-09)
参考文献数
12

Recently, Mineral Trioxide Aggregate (MTA) categorized as calcium silicate cements has been frequently used for root-end filling. MTA is advantageous in sealing of root and hard-tissue formation, and many clinical studies which reported successful results for apicoectomy using MTA are available. 4-META/MMA adhesive resins, which show superior bonding ability to dentin, are also promising materials for root-end filling. However, in addition to durable sealing, abilities to control infection or promote tissue regeneration are important for ideal root filling materials. Therefore, development of new technologies to achieve adhesive resins for root-end filling with antibacterial effects or FGF-2-releasing property is in progress.