著者
影山 進 上田 朋宏 山内 民男 続 真弘 米瀬 淳二 河合 恒雄 井田 時雄
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.40, no.11, pp.1021-1025, 1994-11

We present a case report of a relapse to the mediastinal lymph node alone, 38 months after orchiectomy on surveillance for stage I typical seminoma. The patient, a 63-year-old man, was treated with high inguinal orchiectomy for left testicular tumor and close follow-up. After 38 months from the initial treatment, the chest X-ray film and CT scan revealed mediastinal tumor. Fine needle aspiration cytology performed under the bronchoscopy showed seminoma cells. Complete remission was achieved after three courses chemotherapy of cisplatin, vincristine, methotrexate, peplomycin and etoposide (COMPE). He has continued to be clinically disease-free 8 months after completion of the treatment. According to the available data in the literature, 94% of the recurrences was detected within 3 years after orchiectomy, and 92% involved retroperitoneal lymph node metastases. This is a rare case who had a late relapse in the mediastinum alone.
著者
大山 武司 前川 正信 柏原 昇
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.28, no.4, pp.493-497, 1982-04

We studied the data obtained by administering Tsumura Hachimijiogan to 28 impotent patients and 29 normal individuals. During two weeks of administration, we assessed the efficacy of the drug by examining the answers of the subjects to a questionnaire handed out before administration, the Cornell Medical Index (C.M.I.) and the results of the Yatabe-Guilford (Y-G) tests. We also measured blood testosterone, 17-KS and 17-OHCS, before and after administration to assess the influence of Hachimijiogan on hormone production. 1) Ability of erection: An increased ability of erection was observed in 65.4% of the impotent patients and an amelioration of morning erection in 50% of the patients. An increased ability of erection was observed in 36% of the control subjects, and an amelioration of morning erection in 24%. 2) Efficacy rate of Hachimijogan was 64% in the control group and 76.9% in the impotent group. The efficacy rate as observed by age was 100% for the control subjects who were over 40 years old; it was smallest for the control subjects in their thirties. However, little difference in the efficacy rate was observed with age in the impotent group. 3) Efficacy rate for problem groups: There was no difference between the efficacy rate for the problem groups in the C.M.I. and Y-G tests and the overall efficacy. 4) Efficacy rate by habitus: The drug was very effective for 71.4% of the impotent patients who had a slender build. 5) The side effects most frequently observed were gastroenteritic disorders. In three cases, drug administration was discontinued because of side effects. Side effects were observed at the highest percentage in pyknic subjects, appearing in more than half of them. 6) Blood testosterone, urinary 17-KS, 17-OHCS: There was no significant difference between the values obtained for the patients or control subjects before and after the administration of Hachimijiogan.
著者
斯波 光生 大橋 仲生 稲田 文衛 有馬 滋
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.24, no.6, pp.481-485, 1978-06

Transurethral incision and excision under direct observation was carried out in 15 men with urethral stricture with Storz's pediatric resectoscope (12Fr.). Postoperative result was satisfactory as observed for 2.5 to 15 months in all the cases including 5 cases of stricture of long length, 4.5 to 15.0 cm. This method is recommended as the first choice surgery for stricture of the male urethra.
著者
栢野 想太郎 佐々木 裕 木村 高弘 頴川 晋
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 = Acta urologica Japonica (ISSN:00181994)
巻号頁・発行日
vol.64, no.8, pp.329-333, 2018-08-31

Metanephric adenoma is a rare benign renal epithelial tumor. We have experienced two cases of metanephric adenoma. The first case was a left renal tumor found by ultrasonography in a 26-year-old woman. The abdominal computed tomography (CT) revealed a 90 mm mass that was enhanced slightly in the early phase, and enhanced further in the late phase. Laparoscopic radical nephrectomy was performed with suspicion of renal cell carcinoma. The second case was a right renal tumor found by CT imaging for heart disease in a 64-year-old man. An abdominal CT revealed a 30 mm mass that was the same as our findings in the first case. Laparoscopic partial nephrectomy was performed with the suspicion of renal cell carcinoma. In both cases, tumor cells are positive for WT-1 and CD57 in immunohistochemical staining ; the final diagnosis was metanephric adenoma. It is difficult to differentiate metanephric adenoma from renal cell carcinoma by preoperative imaging ; the diagnosis depends on morphological and immunohistochemical profiles.
著者
田島 惇 大見 嘉郎 阿曽 佳郎 太田 信隆 牛山 知己 畑 昌宏 藤井 一彦 増田 宏昭
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.29, no.3, pp.p365-369, 1983-03

Moristerol was orally administered in 20 cases of benign prostatic hypertrophy. One capsule of Moristerol contained 200 mg of soysterol . In all the cases, 9 capsules of Moristerol were given per day in three divided doses for 6 weeks. Clinical improvement was observed in 11 of the 20 cases (55%). It consisted mainly of subjective complaints such as improvement of dysuria, narrow and weak urinary stream and feeling of incomplete voiding. As objective findings, a statistically significant decrease of residual urine volume was noted after treatment, although shrinkage of the enlarged prostate was not clear upon palpation or roentgenography. In addition to the improvement of symptoms, serum lipid peroxide which might be considered to be a provocative cause of benign prostatic hypertrophy, was also significantly decreased by Moristerol administration. No marked side effects were seen in this study.
著者
安住 誠 佐賀 祐司 橋本 博 柿崎 秀宏
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.52, no.10, pp.781-784, 2006-10

著者版1994年7月〜2005年2月に3ヵ月以上の内分泌療法後に前立腺前摘除術を行い、pT0と診断された11例を対象とした。内分泌療法はLH-RHアナログ単独投与または抗アンドロゲン剤と併用投与が行われていた。病理学的に残存癌を認めない11例中9例は、サイトケラチン染色でも癌病巣は確認できなかったが、2例に残存癌が検出された(症例2と症例7)を報告した。症例2(64歳男)。1997年9月にPSA8.1ng/mlで経直腸的前立腺生検を実施し、低分化型腺癌診断のもとMAB療法を4ヵ月間実施後、翌年2月に根治的前立腺全摘除術を行った。残存癌なしで経過観察中、H-E染色で認識しにくい小腺管構造がAE1/AE3染色で多数確認された。症例7(58歳男)。2003年3月にPSA10.5ng/mlで経直腸的前立腺生検を実施し、中分化型腺癌と診断されMAB療法を5ヵ月実施した。半年後に根治的前立腺前摘除術後、残存癌なしで経過観察中、H-E染色で認識しにくい小腺管構造がAE1/AE3染色で多数確認された。
著者
佐野 克行 寺島 和光 檜作 和子 立花 克彦 田中 祐吉
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.44, no.1, pp.57-59, 1998-01

過去6ヵ月間にファラスが急成長した10歳女児で,尿道口と腟開口部は正常な位置にあり,ファラスは径1.5cm,長さ4cmであった.X線検査で腟,子宮,及び卵管様構造を認めた.核型は46,XY(71.5%),45,X(26%),及びその他(2.5%)を持つモザイク型であった.両側性腺は性腺芽腫を持つ異常発生精巣組織であった.左側では巣状的未分化胚細胞腫が発生していた.両側性腺摘除及び陰核縮小形成術を行った
著者
河 源 谷口 久哲 木下 秀文 松田 公志
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.55, no.2, pp.87-92, 2009-02

A specialized clinic for middle-aged and elderly hypogonadal men was established in our institution five years ago. A retrospective study of the 511 patients who attended our clinic during this period was conducted and the issues involved in treating these patients were identified. The patients' age distribution, symptoms, serum testosterone values, treatment, and course were examined. The patients' mean age was 54.0 years (range, 35 to 74 years); approximately half of the patients were in their fifties. Most patients complained of decline in libido, general fatigue, and erectile dysfunction. The patients' mean serum free testosterone was 9.28 pg/ml; 40.3% of patients had a serum free testosterone value of less than 8.5 pg/ml, which is the threshold value for the initiation of androgen replacement therapy (ART) in Japan. ART was given to 220 (43.1%) patients, and it was considered effective in 100. It appears that male climacteric disorder and late-onset hypogonadism have become commonly recognized in Japan. There will be an increasing need for specialized clinics for such men in the future.
著者
本郷 祥子 野本 剛史 川上 正能 花井 一也 稲土 博右 寺地 敏郎
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.56, no.2, pp.107-110, 2010-02

A 39-year-old man visited our clinic with gross hematuria. Cystoscopy revealed a papillary tumor at the urinarybladder dome. Abdominal magnetic resonance imaging (MRI) and computed tomography(CT) demonstrated a tumor extending from the umbilicus to the bladder dome. Transurethral resection of bladder tumor (TUR-Bt) was performed and histopathological findings revealed adenocarcinoma. Chest CT and examination of the upper gastrointestinal did not reveal anyabnormal findings. The tumor was diagnosed as stage IIIA urachal carcinoma, and en bloc segmental resection was performed. About 10 months later, chest CT demonstrated multiple lung metastases. After two courses of combination chemotherapywith methotrexate (MTX), 5-fluorouracil (5-FU), epirubicin (epiADM), and cisplatin (CDDP), the multiple lung metastases completelydisappeared. The patient has survived 23 months to date with no evidence of disease and is receiving adjuvant chemotherapywith tegafur uracil.
著者
井上 克己 島田 誠 斎藤 克幸 小川 雄一郎 松原 英司 林 圭一郎 松本 祐樹
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 = Acta urologica Japonica (ISSN:00181994)
巻号頁・発行日
vol.61, no.11, pp.441-443, 2015-11-30

A 49-year-old female presented complaining of gross hematuria. Cystoscopy and magnetic resonance imaging revealed a papillary tumor on the bladder dome. At biopsy pathology the tumor was diagnosed as adenocarcinoma. We diagnosed the tumor as urachal adenocarcinoma and performed partial cystectomy of bladder dome with en-bloc resection of the urachal ligament up to the umbilicus. In surgical pathology, the tumor had invaded to the fat tissue around the urachal ligament with metastasis to the lymph node. Therefore the tumor was diagnosed as a stage IVA (Sheldon’scategory) urachal adenocarcinoma. After surgery, 6cycles of chemotherapy with TS-1 and cisplatin (CDDP) were performed. There has been no relapse 5years after surgery. This is the first report of successful adjuvant chemotherapy with TS-1/CDDP for advanced urachal adenocarcinoma.
著者
本郷 祥子 野本 剛史 川上 正能 花井 一也 稲土 博右 寺地 敏郎
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.56, no.2, pp.107-110, 2010-02

A 39-year-old man visited our clinic with gross hematuria. Cystoscopy revealed a papillary tumor at the urinarybladder dome. Abdominal magnetic resonance imaging (MRI) and computed tomography(CT) demonstrated a tumor extending from the umbilicus to the bladder dome. Transurethral resection of bladder tumor (TUR-Bt) was performed and histopathological findings revealed adenocarcinoma. Chest CT and examination of the upper gastrointestinal did not reveal anyabnormal findings. The tumor was diagnosed as stage IIIA urachal carcinoma, and en bloc segmental resection was performed. About 10 months later, chest CT demonstrated multiple lung metastases. After two courses of combination chemotherapywith methotrexate (MTX), 5-fluorouracil (5-FU), epirubicin (epiADM), and cisplatin (CDDP), the multiple lung metastases completelydisappeared. The patient has survived 23 months to date with no evidence of disease and is receiving adjuvant chemotherapywith tegafur uracil.
著者
梶田 洋一郎 羽渕 友則 賀本 敏行 奥野 博 寺井 章人 筧 善行 寺地 敏郎 小川 修 吉田 修
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.46, no.10, pp.711-714, 2000-10

1)Sheldonらの分類でstage IIIA迄の尿膜管癌の初回手術として,臍・尿膜管全摘除術を加えた膀胱部分切除術にて長期の生存,膀胱温存が得られる可能性が示唆された.2)CEAは患者血清4例中2例,尿膜管癌組織5例中5例で陽性であり,尿膜管癌の腫瘍マーカーとなる可能性が示唆された.3)p53は尿膜管癌組織5例中4例で陽性であったが,stageや予後との相関は認められなかった
著者
鈴木 和浩 小沢 雅史 中里 晴樹 黒川 公平 林 雅道 神保 進 小林 幹男 鈴木 孝憲 今井 強一 山中 英寿
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.41, no.3, pp.197-203, 1995-03

74例の胚細胞腫瘍のうち,47例がセミノーマ,27例が非セミノーマであった。4例の非胚細胞腫瘍があった。セミノーマでは非セミノーマに対して高齢発生,低ステージであった。病期1では経過観察した1歳の卵黄嚢腫瘍の1例が再発したが,化学療法にて救命可能であった。病期2では初回に照射療法を施行した3例のセミノーマ,および非セミノーマで再発が認められた。1例のみ救命可能であった。病期3では1例が再発,5例が初回治療より抵抗性を示した。前例死亡した
著者
内田 豊昭 小林 健一 本田 直康 青 輝昭 小俣 二也 遠藤 忠雄 石橋 晃 小柴 健
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.31, no.10, pp.1701-1707, 1985-10

1)膀胱腫瘍10例(11腫瘍)に対してBCG 30 mgから240 mgによる膀胱腔内注入療法を施行した.2) 11腫瘍中7腫瘍に腫瘍消失,4腫瘍に20~80%の腫瘍縮小効果が認められた.3)腫瘍の大きさ別では米粒大腫瘍の4腫瘍は全例消失し,小指頭大の腫瘍では5腫瘍中3腫瘍が消失し,残りの2腫瘍にも著明な縮小が認められた.4)悪性度の判明した8腫瘍についてみるとGrade 1は5例中4腫瘍全例が消失,1腫瘍が50%縮小し,Grade 2は3腫瘍が20~80%の腫瘍縮小を認めた.5)副作用としては,膀胱刺激症状を10例中7例(70%),発熱4例(40%),血尿3例(30%)を認めた
著者
青木 志保 島田 誠 井上 克己 永田 将一 斎藤 克幸 小川 雄一郎 松原 英司 前田 智子 菅原 基子 林 圭一郎 松本 祐樹
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.58, no.6, pp.287-290, 2012-06

We report a case of vesical endometriosis that worsened during the early pregnancy period. A 37-yearold woman had been under treatment for endometriosis (including vesical endometriosis) by a gynecologist during the past 10 years. She was treated for sterility 1 year ago, and became pregnant through in vitro fertilization. In her 8th gestational week, she complained of gross hematuria at our hospital. Cystoscopic findings revealed some tumors that appeared worse than the last findings two years ago. In order to deny malignancy, transurethral resection of the bladder tumor was performed in her 12th gestational week. The pathologic diagnosis was endometriosis. She was able to stay pregnant, and delivered a girl. After delivery, cystoscopic findings revealed reduction of tumors. In most cases pregnancy cures endometriosis ; however, in this case symptoms became worse during the early stage of pregnancy. The reason for this contrary event is discussed.
著者
百瀬 剛一 島崎 淳 片山 喬 遠藤 博志
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.6, no.8, pp.673-681, 1960-08

We report 3 cases of females with congenita l masculinization of the external genitalia, who were born of mothers treated with certain oral progestins during pregnancy (2 are ethynyltestosterone and the other one, 17a-ethynyl-19 nortestosterone).
著者
田島 政晴
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.34, no.11, pp.2013-2020, 1988-11
被引用文献数
2

Orchidometer "Test size"にて1歳未満~86歳1782睾丸の計測を行った.睾丸容積は,8歳ごろまで発育が緩かで,12~13歳ごろから増加率が速やかとなり,18~19歳前後でピークに達し,それ以後はプラトーに移行した.従来の報告値より高値を示した.真の睾丸の実測容積は,Test sizeは,計測値に係数0.608をかけ,超音波断層法では係数1.098をかければ算出できる
著者
伊藤 坦 川村 寿一 王 本欽 吉田 修 藤田 透 鳥塚 莞爾
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.26, no.10, pp.p1221-1228, 1980-10
被引用文献数
2

Diagnostic validity of renal scintitomography using 99m-Tc-DMSA was investigated in 16 cases with a variety of renal space occupying lesions. The serial sagittal section of renal images with a 0.5 to 2.0 cm distance well revealed a localization of space occupying lesions in the kidney. Although renal scintitomography does not differentiate malignant solid tumors from cystic renal mass, its usefulness is evaluated in the combination with IVP and renal scintigrams consisting of early dynamic and late static images or with IVP and ultrasonography.
著者
山田 瑞穂 西浦 力 川上 一郎
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.3, no.9, 1957-09

En general, la tumeur embryoide mixte du rein est observee chez l'enfant. Selon les statistiques, plus 80 % des malades de cette tumeur sont des enfants de moins de 6 an s, mais les adultes se trouvent dans la proportion de 6 ou 7 %. Nous avons observe un cas de cette tumeur chez une malade de 57 ans. Observation : II s'agit d'une malade A gee de 57 ans. II y a une annee, et deux mois, elle avait manifesto de l'hematurie, et depuis un mois, elle a commence a sentir des douleurs au rein gauche et a l'abdomen gauche ; depuis une semaine elle a manifes to une tres forte hematurie. L'aspect ge n eral est celui d'une personne maigre et anemique. On sent dans la partie gauche de l'abdomen le rein grossi de la grosseur de la the d'un enfant. Cystoscopie On ne trouve aucun eta. morbide, mais on observe une u rine sanglante sortant par l'orifice ureteral gauche ; l'examen d'indigocarmine est negatif du cOt e gauche. Radiographie Pyelo-uretero-graphie ascendente par radioscopie, le bassinet et l 'u retre droit sont un peu dilates, mais a gauche le bassinet et d'uretre sont gigantesques . (Fig. 1, 2, 3) R esultat de l'intervention chirurgicale Nephrectomie gauche par anesthesie generale d'Heidbrink. On a extirpê le rein gauche qui etait tres grand et qui adherait forte ment l'aorte et au tissu conjonctif environnant' mais on n'extirpa pas une metastase lymphoide environnant l'aorte. La dimen s i o n du rein extirpe est de 16 c m x 13.5 cm X1 0 c m ; et le poids est de 1.225 g ; l'uretre a 30 cm de longueur et 5.5 cm de largeur. he rein est presque entierement occupe par le tissue de la tumeur. (Fig. 4, 5) Les suites operatoires sont favo r a bles. Cependant, comme l'anemie etait tres forte (erythrocyte est 287 X 1 04, contenu hemoglobine par Sahli est 48 %, leucocyte est 3,4 00), on ne pouvait pas faire de radio-therapie. Sur ces entrefaites, la tumeur metas t atique restee grossissait dans le flanc gauche. Apt-es un mois, on a pratique la radio-the rapie, mais apres l'avoir poursuivie pendant environ 30 jours it a fallu suspendre le traitement a cause de l'anemie. En 3 mois, cette tumeur a metastase aux ganglions lymphatiques du bile du poumon. La patiente est morte 5 mois apres l'intervention. Anatomine pathologique On trouve la metastase aux poumons, au foie, au corps surrenal droit, et aux ganglions lymphatiques retroperitonal, autour de l'aorte, du hile du poumon, sur la clavicule gauche, autour de la trachee, de la bifurcation de la trachee, du Nile du foie, et de la petite coubure de l'estomac. (Fig. C, 7) Pathologie microscopique : Dans le tissu de la tumeur ex tirpee, on trouve une formation serree des cellules, mais on ne trouve pas une formation en nid ; la disposition des cellules rappelle un peu celle d'une glande, ou d'un glomerule, mais on ne trouve pas de tissu glandulaire a proprement parles, ni d'os. ni de cartilage, ni de muscle etc L'observation des tissus de la metastase est presque la même que celle de la tumeur primitive. (Fig. 8, 9, 10, 11)