著者

石川 敏夫 市村 恵一

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.97, no.4, pp.285-290, 2004-04-01 (Released:2011-10-07)

参考文献数

20

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The clinical features of 14 patients with deafness due to mumps who underwent treatment in Jichi Medical School Hospital from April 1993 to March 2003 were reviewed. The diagnosis was made according to the criteria for diagnosis of mumps deafness determined by the Acute Profound Deafness Committee set up by the Ministry of Health and Welfare, Japan.The number of patients with mumps has gradually increased since 2000, and the number of patients in 2002 was about 3 times greater than that in 2000.The age distribution of the patients in our hospital was 3 to 34 years old and half of the patients were 5 to 9 years old. The onset time of hearing loss in 10 cases was within 8 days after the appearance of parotid swelling. All 14 patients had unilateral total deafness or profound sensorineural hearing loss. Nine were treated with corticosteroids. Hearing loss did not improve after treatment in any patient. The importance of mumps vaccination should be reconsidered.

著者

大屋 耕子

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.96, no.6, pp.499-502, 2003-06-01 (Released:2011-10-07)

参考文献数

15

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Natural mumps virus infection is believed to induce lifelong immunity and rarely cause unilateral severe sensorineural hearing loss with sudden onset. Unilateral deafness due to mumps virus reinfection had rarely been reported in the Japanese literature. I present a case of unilateral deafness due to mumps virus reinfection.

著者

五島 史行 矢部 はる奈 小川 郁

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.102, no.4, pp.315-320, 2009 (Released:2010-12-04)

参考文献数

15

被引用文献数

1 1

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Introduction: Treatments for acute peripheral vertigo have not been well investigated. The most suitable drug for controlling acute vertigo should suppress both vertigo and accompanying nausea. The purpose of this study was to evaluate the effect of four different drugs on acute peripheral vertigo: (A) hydroxyzine hydrochloride (25 mg, i.v.); (B) 0.5% metoclopramide (2 ml, i.v.); (C) sodium bicarbonate (40 ml, i.v.); and (D) a cocktail of diphenhydramine hydrochloride (30 mg) and dyprophylline (26 mg) (both i.m.). Methods: Forty-two patients with acute peripheral vertigo (average age: 59.5±18.1 years) with spontaneous nystagmus were assigned to four treatment groups (A-D, above). Patients with central vertigo and vestibular neuritis were excluded. The number of patients in each group was as follows: A, n=11; B, n=11; C, n=11; and D, n=9. Patients were instructed to evaluate their subjective symptoms of nausea and vertigo before and 30 minutes after drug treatment. They rated the severity of their symptoms on a 0-to-10 scale, with 10 representing the most severe symptoms and 0 a lack of symptoms. Results: Group A patients (hydroxyzine hydrochloride; 25 mg, i.v.) reported the highest level of relief from vertigo and nausea after drug treatment, whereas group C (sodium bicarbonate; 40 ml, i.v.) and D (diphenhydramine hydrochloride (30 mg)-dyprophylline (26 mg) cocktail; i.m.) patients reported only the slight relief of these symptoms. Group B patients (0.5% metoclopramide; 2 ml, i.v.) experienced partial symptom relief; their vertigo remained unchanged. Thus, hydroxyzine hydrochloride (A) was the most effective in controlling both nausea and vertigo, whereas sodium bicarbonate (C) and diphenhydramine hydrochloride and dyprophylline (D) only slightly suppressed vertigo and nausea. Metoclopramide (B) only suppressed nausea. Conclusions: Hydroxyzine hydrochloride (A) was the most suitable for treating acute peripheral vertigo. Doctors should be familiar with the contraindications of these drugs. Some of these drugs may potentially be used in combination to control the symptoms of acute vertigo more effectively.

著者

多湖 千晃 柳田 則之 成内 秀雄 落久 保文子 倉田 毅

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.84, no.11, pp.1625-1631, 1991

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We investigated the role of immunological mechanisms in sensorineural hearing disorders and the relationship between inner ear and renal pathologies.<br>Controls, and NZB/kl and MRL/lpr strain mice, in which autoimmune disease can be spontaneously induced, were used in this study. The mice were tested for acoustic brain stem response (ABR), cochlear and renal pathology and circulating immune-complexes (CIC) serology, using enzyme immunoassay (ETA). For ABR, click and high frequency tone bursts were used as stimuli. Pathological studies consisted of tissue changes observed following hematoxylin-eosin (HE) and indirect immunofluorescent staining under light microscopy.<br>Compared to controls, hearing was impaired in NZB/kl mice while hearing remained unaffected in MRL/lpr mice. On HE staining, no histological changes were observed in the cochleae of either strain of mice. However, indirect fluorescent staining showed IgG deposits in the stria vascularis in both strains of mice. In both strains, renal pathology consisted of an immune-complex glomerulonephritis. CIC values were significantly higher in MRL/lpr mice, but were not correlated to stria vascular lesions. The lesions in the stria vascularis in the two strains were different, which probably explains the discrepancy in hearing impairment, whereas the lesions in the kidney were similar. NZB/kl mice that had hearing impairment showed severe stria vascular lesions and there was a correlation between the degree of hearing impairment and the severity of stria vascular lesions. However, no correlation was seen between stria vascular and renal lesions and CIC values.<br>These findings suggest that autoimmune mechanisms exist yin the cochlea, mainly in stria vascularis. The NZB/kl mouse can be a useful model of sensorineural hearing disorder secondary to immunological disorders.

著者

岡田 昌浩 小林 泰輔 中村 光士郎

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.102, no.3, pp.219-223, 2009 (Released:2010-12-03)

参考文献数

20

被引用文献数

9 10

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Hemorrhage following tonsillectomy is still a major complication despite the development of new hot knives. In this study, a retrospective review of 242 adult patients who underwent tonsillectomy in the Department of Otolaryngology, Ehime Prefectual Central Hospital between January 2000 and March 2007 was conducted. Post-tonsillectomy hemorrhage occurring in 56 patients (23.1%); four of these patients experienced hemorrhage during the first 24 hours postoperatively, and the remaining 52 had delayed bleeding. Nine of 56 patients (3.7%) required a procedure to control their bleeding under general anesthesia. The hemorrhage rate in males was significantly higher than in females. There was no statistically significant difference in hemorrhage rates based on age, body mass index (BMI), duration of surgery and smoking. Patients who received antibiotics postoperatively experienced less secondary hemorrhage than those without antibiotics. In 99 patients who were administered antibiotics, patients who used cephalosporins experienced less secondary hemorrhage than those who received penicillins. These results indicate that antibiotics after tonsillectomy are effective to reduce post-tonsillectomy hemorrhage rates.

著者

小林 丈二 佐伯 忠彦 竹田 一彦 上甲 英生

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.89, no.11, pp.1365-1369, 1996-11-01 (Released:2011-11-04)

参考文献数

14

被引用文献数

1 2

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The authors investigated the clinical course of 49 patients with peritonsillar abscesses treated at Uwajima City Hospital between January 1983 and December 1995. The cohort consisted of 36 males and 13 females, aged 15 to 68 (mean age, 37.2 years old). Along with administration of antibiotics, removal of the abscess was performed by needle aspiration in 25 cases, and incision for drainage in 24 cases, respectively. There were no statistical differences in clinical stage and course between the group under 40 years old and the group over 40 years old. There was also no difference between the group treated with needle aspiration and the group treated with incision, except for the length of hospital stay healing time. Interval tonsillectomy was carried out in 10 cases. Recurrence of the peritonsillar abscess occurred in only one case. Therefore, we recommend needle aspiration as the first choice for treatment of peritonsillar abscesses. In cases of peritonsillar abscess with no past history of habitual angina, tonsillectomy is not indicated because recurrence of peritonsillar abscesses is rare.

著者

仁保 正次 濱谷 松夫

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.38, no.4, pp.212-221_3, 1943-04-20 (Released:2011-10-14)

参考文献数

29

著者

石島 健 野々村 光栄 藤木 暢也

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.88, no.6, pp.739-742, 1995-06-01 (Released:2011-11-04)

参考文献数

12

被引用文献数

2 2 4

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A patient with right exophthalmus due to exacerbation of relapsing sinusitis who had undergone bilateral radical paranasal sinus surgery in our hospital 6 months earlier visited us and was diagnosed with acquired immunodeficiency syndrome (AIDS) after many tests. The patient was a 36-year-old male who had consorted with prostitutes. Esophageal candiditis and tumors of the liver and the colon were found. Blood tests showed a reduction in lymphocytes, particularly in T-cells and an CD4/CD8 ratio of 0.2. HIV (human immunodeficiency virus) antibody titer was increased. Remission of exophthalmus came after therapy with steroids and antibiotics.

著者

中村 光士郎 松本 康 柳原 尚明

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.73, no.11, pp.1673-1678, 1980-11-01 (Released:2011-11-04)

参考文献数

19

被引用文献数

1

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Bilateral or recurrent facial palsies were found in 70 patients (3.8%) among the 1856 patients with facial palsy whom we treated during the last fifteen years. According to the clinical course, these 70 patients were classified into the following four groups.1) Bilateral simultaneous facial palsy (15 patients, 0.8%)2) Bilateral recurrent facial palsy (3 patients, 0.2%)3) Bilateral alternating facial palsy (24 patients, 1.3%)4) Unilateral recurrent facial palsy (28 patients, 1.5%)The bilateral simultaneous facial palsies were caused by Bell's palsy in five patients, head trauma in three, the Melkerson-Rosenthal syndrome in one, otitis media in two, myasthenia gravis in two, polyneuritis in two. The etiologies of four other patients were unknown. In contrast to multiple etiologies of the bilateral simultaneous facial palsies, bilateral alternating and recurrent palsies were caused mostly by Bell's palsy (22 patients) and the Melkerson-Rosenthal syndrome (3 patients). Although the majority of unilateral recurrent facial palsies were caused by Bell's palsy (22 cases) and the Melkerson-Rosenthal syndrome (2 cases), it is noteworthy that intratemporal tumors such as neurinoma of the facial nerve (1 patient) and cholesteatoma in the petrous apex (2 cases) could be the cause of recurrence.

著者

長山 郁生

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.76, no.11special, pp.3136-3140, 1983-11-20 (Released:2011-11-04)

参考文献数

9

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The body sway of patients in a position standing was recorded by a stabilometer. Each subject stood on a platform with feet together and looked straight ahead at a small spot on a wall 1.5m away. The test was done for 35 seconds with eyes open and another 35 seconds with eyes closed.The total distance of body sway and the shift of the center of the stabilogram were measured. The test was performed on normal subjects and patients with vestibular disorders.(1) In patients with vestibular disorders, the total distance of body sway was greater than in normal subjects, and its ratio with eyes closed and eyes open was larger than normal.(2) Normal subjects shifted forward with eyes closed, but the patients tended to shift backward.These two indicators, the total distance of body sway and the shift of the center of the stabilogram provide useful information in observing the clinical course of patients with vestibular disorders.

著者

村井 紀彦 佐藤 宏昭

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.87, no.7, pp.909-912, 1994-07-01 (Released:2011-11-04)

参考文献数

13

被引用文献数

2 5

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A 42-year-old man was referred to our hospital because of left nasal obstruction. Anterior rhinoscopy disclosed a mass in the left nostril attached to the nasal septum. CT scanning showed a well-demarcated soft tissue density mass in the anterior part of the left nasal cavity. Biopsy revealed that the mass comprised spindle cells without atypia. Under local anesthesia the tumor was removed by the transnasal approach. The histopathological diagnosis was neurilemmoma.

著者

山根 英雄

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.98, no.12, pp.907-914, 2005-12-01 (Released:2011-10-07)

参考文献数

29

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Surgery for congenital aural atresia is among the most difficult and challenging procedures for both ear surgeons and patients. Some previous reports have not recommended this type of surgery with confidence, because of the difficulty of the surgery itself and because postoperative hearing gain has not been as good as was expected, while postoperative complications such as middle ear infection sometimes occur. How then should the otolaryngologist approach this disease? When microtia coexists with aural atresia, the otolaryngologist sometimes hesitates to decide how to treat atresia because of excessive attention to microtia. The difficulty of atresia surgery should be considered apart from microtia because the microtia itself is not a crucial factor in such surgery. At present, it is hoped that otolaryngologists will develop several strategies such as reliable surgery with good postoperative hearing results without postoperative complications and new devices such as BAHA.

著者

生井 明浩 池田 稔 吉川 拓磨 工藤 逸大 小野田 恵子 木田 亮紀

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.92, no.7, pp.801-804, 1999-07-01 (Released:2011-11-04)

参考文献数

10

被引用文献数

2 2

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Polaprezinc is an anti-ulcerative drug that contains zinc. We used this drug for the treatment of 41 taste disorder patients (21 to 76 years). The rates of improvement were 80.0% in drug-induced, 100.0% in zinc deficient, and 62.5% in idiopathic taste disorders. The overall rate of improvement in all patients was 73.2% (30 cases). These results revealed that polaprezinc is useful for taste disorder patients lacking zinc.

著者

水越 文和 出島 健司 竹中 洋 齊藤 憲治 河田 了 高木 伸夫 安田 範夫 村上 泰 松岡 秀樹 日向 美知 立本 圭吾 任 書熹 大島 渉 寺薗 富朗 日向 誠 松本 真吏子 竹上 永佑 土井 玲子 三牧 三郎 西嶋 信雄 牛島 千久 伊達 敬一 園田 隆朗 大槻 晃直 木村 隆保 八木 正人 中井 茂 昌子 均 豊田 健司

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床. 補冊 = Practica otologica. Suppl. (ISSN:09121870)

巻号頁・発行日

vol.76, pp.56-66, 1995-03-20

被引用文献数

6 2

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The effect of Oxatomide in the initial treatment of Japanese cedar pollinosis was examined in 11facilities in Kyoto prefecture. This study examined the most appropriate starting time and period of administration for the highest effect of the initial treatment. The following results were confirmed by administre ring Oxatomide during the initial treatment for Japanese cedar pollinosis on 1991.<BR>The effect of Oxatomide was obtained after administering for one week or more, including the highest effect after two weeks for sneezing and three weeks for nasal discharge. However, no effect on sniffling. These results suggest that two to three weeks is the best administration period for Oxatomide in the treatment of Japanese cedar pollinosis.<BR>In addition, a close relation between pollen information facilities and practical medicine in the region, is necessary for the initial treatment of pollinosis.

著者

北原 糺 村田 潤子 小畠 小畠 奥村 新一 江崎 光彦

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.91, no.8, pp.845-849, 1998-08-01 (Released:2011-11-04)

参考文献数

11

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In this paper, a very rare case of vasculo (angio)-Behcet's disease initiated with hoarseness due to inflammatory aortic aneurysm, is presented. A 35 year-old male with persistent hoarseness for half a month was revealed to have left recurrent laryngeal nerve palsy. Chest X-ray films showed slight enlargement of the aortic arch. CT demonstrated direct evidence of a saccular type aortic aneurysm at the branched area of the left subclavian artery. Aortic angiography demonstrated two additional aortic aneurysms at the right subclavian artery and in the lower abdominal area. The patient subsequently underwent emergency surgery for treatment of these aneurysms. The histopathological characteristics of the representative aortic aneurysmal lesions suggested a diagnosis of “vasculo-Behcet's disease”. Behcet's disease is usually characterized by oral and genital ulceration, folliculitis and uveitis. This patient, however, displayed no previous evidence of these symptoms. We would like to emphasize that some cases of left recurrent laryngeal nerve palsy require urgent management.

著者

近藤 律男 榎本 浩幸 田口 享秀 長原 太郎 佃 守

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.98, no.4, pp.309-313, 2005-04-01 (Released:2011-10-07)

参考文献数

21

被引用文献数

1

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Behçet's Disease is a systemic disease characterized by mucosa, dermis and eye lesions. Otolaryngologists sometimes examine patients of this disease who complain of inveterate aphthae. Patients with Behçet's Disease often have histories of tonsillitis and many caries of the tooth. Based on these facts, streptococcus in the oral cavity is suspected to be closely related to this disease.We report a case of Behçet's Disease whose first symptom was acute tonsillitis.A 33-year-old male complaining of sore throat and elevated fever was referred to our hospital. Oral aphthae was seen and the bilateral palatine tonsils were swollen, reddish and coated with fur. We diagnosed acute tonsillitis and treated him with antibiotics. However, elevated fever, inflammation and oral aphthae were not remitted and a pudendal ulcer appeared. We suspected Behçet's Disease and consulted with doctors of internal medicine, dermatology and ophthalmology. Fourteen days after admission, folliculitis and arthritis appeared and finally he was diagnosed with incomplete type Behçet's Disease.This case suggests that tonsillitis is closely related with the appearance of Behçet's Disease. Furthermore, oral aphthae and tonsillitis are very important symptoms regarding Behçet's Disease, in patients with oral aphthae.

著者

岩崎 久藏

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.35, no.5, pp.425-434, 1940-05-20 (Released:2011-10-14)

参考文献数

15

著者

西村 宏子 山本 悦生 山内 盛雄 岩永 迪孝 藤田 佳代子 岩崎 博 佐藤 宏昭 竹内 俊二 鶴原 秀晃

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.76, no.2special, pp.328-337, 1983 (Released:2011-11-04)

参考文献数

31

被引用文献数

1

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昭和52年1月から昭和57年9月までの6年9ヵ月間, 京大病院耳鼻咽喉科を訪れた顔神麻痺患者662名について統計的観察を行い以下の結果が得られた.(1) 顔神麻痺患者は, 外来新患数の1.8%を占めていた.(2) 年度別発生件数では, 各年ともベル麻痺が1番多く, 62.0~80.5%を占め, その他の頻度はまちまちであった.(3) 診断別分類では, ベル麻痺が1番多く, 447例 (67.5%), 以下, ハント症候群59例 (8.9%), 手術損傷性45例 (6.8%), 頭部外傷性45例 (6.8%), 先天性23例 (3.5%), 耳炎性15例 (2.3%), 中枢性6例 (0.9%), 側頭骨外疾患4例 (0.6%), 聴神経腫瘍2例 (0.3%), その他16例 (2.4%) であった.(4) ベル麻痺, ハント症候群における男女の差は著明でなかった.(5) ベル麻痺, ハント症候群とも左側にわずかに多かった.(6) ベル麻痺, ハント症候群の月別発生頻度は, 前者は11月に少なくなっている他は著明な差は見られなかった. 後者も季節的な一定の結論を出すのは困難であった.(7) ベル麻痺, ハント症候群とも青壮年が多く罹患していた.(8) 再発性麻痺は40例あり, 一側反復性麻痺14例, 両側交代性麻痺25例, 両側同時性麻痺1例を含んでいた.(9) ウイルス感染については, 検索を行った73例のうち, 感染ベルは21.3%で, ハント症候群では75%に帯状疱疹ウィルスに感染が認められた.

著者

岩塚 和子

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.98, no.6, pp.447-452, 2005-06-01 (Released:2011-10-07)

参考文献数

11

被引用文献数

2 1

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A 31-year old woman with Churg-Strauss Syndrome (CSS) including eosinophilic otitis media is presented. Other manifestations included an 11-year history of nasal allergy followed by bronchial asthma, sinusitis with nasal polyps, eosinophilic pneumonia accompanied by peripheral eosinophilia (34% of 6, 600/μl leukocytes), and erythema in both legs. Repeated episodes of painless right otitis media occurred without fever during the first stage of CSS characterized by an allergic state. This progressed to bilateral otitis media with gelatinous mucoid fluid accumulations shortly before the second stage of CSS characterized additionally by peripheral eosinophilia and eosinophilic pneumonia. Numerous eosinophils were found in gelatinous fluid within the tympanic cavity.The patient was diagnosed with bilateral eosinophilic otitis media, which was controlled by nebulizer therapy with 2% fosfomycin and 0.2% betamethasone solution directed into the Eustachian tube and tympanic cavity. Hearing loss and vertigo have been avoided. This case strongly suggests that eosinophilic otitis media can be a manifestation of CSS.

著者

立木 孝

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.75, no.2, pp.305-315, 1982 (Released:2011-11-04)

参考文献数

58

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The idea that sensorineural hearing loss without an associated conductive loss due to stapes fixation can be attributed to otosclerosis is presented.The literature on sensorineural hearing loss in otosclerosis is reviewed. Although a considerable number of related findings seems to support this idea, no confirming evidence has been found.It has been believed that otosclerosis is rare in Japan and many otologists are uninterested in the idea of inner ear otosclerosis. Recently, however, some investigators reported a considerable number of patients with clinical and/or histological otosclerosis.There are many cases of sensorineural hearing loss of unknown cause and its etiology has been a matter of concern.As inner ear otosclerosis is clinically characterised by sensorineural hearing loss of unknown origin, it should be included in differential diagnosis when evaluating the etiology of sensorineural hearing loss in general.