著者
花田 武浩 鯵坂 孝二 今給黎 泰二郎 古田 茂 大山 勝
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.89, no.1, pp.11-19, 1996-01-01 (Released:2011-11-04)
参考文献数
21

Patients with sudden deafness who were treated either in our department or in our branch hospital between January 1984 and December 1994 were divided into two groups. Group A consisted of 69 patients who were treated with steroids, vasodilators, and stellate ganglion block but without hyperbaric oxygen therapy. Group B consisted of the other 85 patients who were treated with not only steroids, vasodilators, and stellate ganglion block but also with hyperbaric oxygen therapy. Patients in the two groups showed no significant difference in age, or number of patients with vertigo, but the initial audiogram was worse and time from onset to consultation were significantly greater in group B than those in group A. The prognoses of the two groups were analyzed by several issues, such as initial audiogram, time from onset to consult and there was no significant difference.
著者
榎本 美紀 佐々木 直子 福本 和彦
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 補冊 (ISSN:09121870)
巻号頁・発行日
vol.156, pp.117-121, 2021 (Released:2021-03-11)
参考文献数
12

We report two cases in which drooling was reduced by percutaneous use of scopolamine ointment. Case 1: A 75-year-old female patient with amyotrophic lateral sclerosis (ALS). In addition to low-pressure continuous suction of the mouth, she was started on scopolamine ointment applied over the postauricular region. Before the ointment was prescribed, the volume of continuous suction was 400 ml/day, whereas it decreased to 150 ml on day 1 and to 200 ml on day 2 after the start of ointment application. Case 2: A 17-year-old female patient with cerebral palsy. If the score on Numeric rating scale (NRS) for the caregiver’s burden before the start of ointment application was 10, the score decreased to 2–4 after 4 hours and 1–3 after 24 hours of ointment application. Two and a half days after the ointment application, there was an objective increase in the amount of saliva, so that the application interval was shortened from every 3 days to every other day. Thereafter, there was a consistent decrease in the amount of saliva. Scopolamine is known to have side effects such as dryness of the mouth, drowsiness, blurred vision and mydriasis, constipation, and urinary retention. However, even after several months of use, no side effects have been observed in either case. We present some review of the literature, including on instructions for preparing and using scopolamine ointment.
著者
金谷 浩一郎 今手 祐二 竹本 剛 蓮池 耕二 綿貫 浩一 守谷 啓司
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.95, no.2, pp.203-209, 2002-02-01 (Released:2011-11-04)
参考文献数
28
被引用文献数
1 2

PURPOSE: Tsumura Co.'s Bakumondo-to (TJ-29) is a Chinese herb medicine prescribed widely in Japan for bronchitis and laryngitis. It is well known that TJ-29 not only has a variety of effects including anti-inflammatory and antitussive properties, but also is capable of increasing salivary secretions. The purpose of this study is to examine whether TJ-29 can reduce mucosal toxicity caused by radiotherapy in patients with early laryngeal carcinoma.METHODS AND MATERIALS: Between 1993 and 1999, 20 patients with primary early laryngeal carcinoma were treated by radiotherapy at Nagato General Hospital. All patients were treated with 2 Gy per fraction daily, 5 days a week. Eight patients formed the control group (no TJ-29) and 12 patients received TJ-29 throughout the radiation therapy. The severity of daily subjective symptoms such as hoarseness, xerostomia or pharyngoxerosis, cough, and sore throat were graded O to 3 according to descriptions on the clinical charts.RESULTS: No statistically significant between-group differences were seen in subjective hoarseness, xerostomia or pharyngoxerosis, and cough. However the mean final grade of subjective sore throat was less severe in the TJ-29 group (p=0.023).CONCLUSION: Despite the limited number of patients, this study suggests that TJ-29 was able to reduce the severity of mucositis induced by radiotherapy. Further intensive research is needed.
著者
寺嶋 正治 加藤 太二 小林 仁和 宮国 泰明 田中 弘之
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.82, no.6, pp.805-817, 1989-06-01 (Released:2011-11-04)
参考文献数
22

Otteosynthesis using Champy's miniplates was performed in 8 patients with mid-face injuries. Since no patients complained of discomfort, we did not remove the miniplates which are thin and light. Miniplate osteosynthesis may be very useful in case of complicated fracture or old fracture of mid-face.
著者
藤木 暢也 内藤 泰 塩見 洋作 平野 滋 本庄 巖 長峯 隆 柴崎 浩
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.89, no.12, pp.1499-1506, 1996-12-01 (Released:2011-11-04)
参考文献数
15

Event-related magnetic fields (ERFs) were recorded in seven subjects when they were presented with a rectangle and Japanese Kanji characters, followed by vocalizations. The ERF averages for the Kanji characters were different from those for the rectangle at latencies of about 100ms over the occipital lobe and 150-500ms over the temporo-parieto-occipital region. This observation suggests that the first stage of visual word processing might arise in the occipital lobe.In some cases, difference between the ERFs for the Kanji characters and those for the rectangle were also seen in the frontal lobe at latencies greater than 250ms. This observation suggests that frontal lobe activity may be also involved in visual word processing.Three equivalent current dipoles were estimated on the bilateral precentral gyrus (motor area) and the posterior part of the superior frontal gyros (supplementary motor area) at a latency of about 500ms during vocalization.In some cases, early responses at latencies of less than 150ms were obtained in not only the occipital lobe but also the frontal and temporal lobes. This suggests that parallel processing might occur during visual word processing.
著者
小池 靖夫
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.80, no.9, pp.1338-1340, 1987-09-01 (Released:2011-11-04)
参考文献数
2
著者
大越 俊夫
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.99, no.11, pp.891-896, 2006-11-01
参考文献数
15

Abnormal sensations in the throat can be induced by a wide variety of causes, and therefore requires both mental and physical approaches to treatment. In addition, malignant tumors maybe detected in a small number of patients with complaints of abnormal sensations in the throat, and this must never be overlooked. While there have been numerous reports descring various tests, diagnostic methods for determining the causes of abnormal sensations in the throat as well as administration the of therapeutic drugs vary among facilities and few reports have investigated cases of abnormal sensations refractory to initial treatment. Furthermore, although the involvement of psychogenesis in this illness is not small, the extent of its involvement is extremely difficult to assess. While therapeutic determination using various psychological tests and the effects of mild tranquilizers has been attempted, clarification of the extent of psychogenic involvement in this illness remains difficult, as does the treatment of this illness as a psychosomatic illness in the field of otolaryngology.<br>Improvement in abnormal sensations in the throat is determined by changes in the subjective symptoms of the patient. Many reports on the treatment of abnormal sensations in the throat have focused on the effects of administering a specific drug in response to a defined cause of illness, and few have reported the final improvement rates of the patients included in these studies. In other words, it is important to investigate secondary and tertiary treatment methods and the extent to which abnormal sensations in the throat has been improved in patients with abnormal sensations refractory to initial treatment, as well as the appropriate course of action when improvements are not observed.
著者
甲斐 智朗
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.95, no.7, pp.679-684, 2002-07-01
参考文献数
9
被引用文献数
2 1

Two cases of psychogenic hearing loss in adults are presented with the process of their mental states. Case 1 was a 20-year-old male who complained of unilateral hearing loss and tinnitus on his left side after receiving a &ldquo;karate&rdquo; kick on his left temple. Considering the perforation of his left tympanic membrane, his left hearing level was much worse (77.5 dBHL). Later examination of ABR revealed the sensorineural system to be intact, and functional hearing loss was suspected. Further questions about his history disclosed that he was extremely unhappy in his job and wanted to leave his present employment. After discussion with psychiatrists, the diagnosis of psychogenic hearing loss was established.<br>Case 2 was a 23-year-old male who complained of right tinnitus after hearing rifle shooting during night time maneuvers in the Self Defense Forces. In spite of the normal appearances of his external and middle ear, his hearing level was 72.5dBHL. Being treated as acoustic trauma, ABR was performed and it resulted in a completely normal response. In this case, the diagnosis of psychogenic hearing loss was also established.<br>Especially in adults, psychogenic hearing loss is regarded as a kind of conversion disorder. In this disease, getting ill brings some &ldquo;gain&rdquo; to the patients. Admission to the hospital separates a patient from his unpleasant job and persons (secondary gain). This is almost compatible with the mental state of case 1. When their desires are converted to physical disorders and are appreciated by another person, they don't have to be concerned by their source of annoyance. Thus their mental states are stabilized (primary gain). This is almost compatible with the mental state of case 2.<br>When assessing patients of Psychogenic hearing loss, their mental states should be considered as there may be various processes involved in the disease.
著者
伊藤 信輔 小田原 修一 山口 勝矢 平野 実
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.82, no.12, pp.1719-1725, 1989-12-01 (Released:2011-11-04)
参考文献数
15

The relationship between the direction of rotation and the leg supporting the body in figure-skating was thought to be based on the cristo-spinal reflex. Skaters stand or jump with the leg of the same side as the rotation when turning around a vertical axis. This suggests that the movement of endolymphatic fluid towards the ampulla of the ipsilateral horizontal semicircular canal as the direction of rotation exerts a facilitatory action on the extensor neurons. On the other hand, they land on the ice with the opposite leg after turning in the air. This can be interpreted as a phenomenon similar to postrotatory nystagmus; that is, the ampullopetal flow takes place in the semicircular canal opposite to the rotation after cessation of turning, resulting in activation of this canal.
著者
荻野 敏 原田 保 坂口 喜清 柳 英博 丹生 真理子 仙波 治 入船 盛弘 田矢 直三 野入 輝久 坂本 邦彦 荻野 仁
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.91, no.2, pp.199-204, 1998-02-01 (Released:2011-11-04)
参考文献数
7
被引用文献数
4 5

Treatment of tinnitus is often difficult. In this study, we evaluated the effectiveness of a Chinese medicine, Gosha-jinki-gan, for the treatment of tinnitus. Forty-two cases, comprising a total of 58 ears, received Gosha-jinki-gan at a dose of 7.5 g a day for at least 4 weeks. Efficacy was evaluated on the basis of changes in symptoms before and after treatment. In total, twenty-seven out of 58 ears (46.6%) improved. The final improvement rate was higher in the group with hearing loss than in the group without hearing loss. It was also greater in the group without pre-treatment than in the group with pre-treatment, however, co-treatment did not influence the improvement rate. No adverse reactions were evident. From these results, it was thought that Gosha-jinki-gan might be useful in the treatment of tinnitus.
著者
山田 弘之 久保 将彦 村井 須美子 坂倉 康夫
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.80, no.7, pp.1163-1168, 1987-07-01 (Released:2011-11-04)
参考文献数
12

Large doses of metoclopramide as an antiemetics were administered to 9 patients recieving cisplatin (CDDP) (50mg/m2) for head and neck cancers. Metoclopramide, 2mg/kg was administered four times intravenously on the first day of CDDP therapy and once a day on days 2-7. Neither emesis nor nausea occurred in 8 of the 9 patients (89%). Side effbcts were minimal: mild sleepiness(66.7%)and diarrhea(22.2%). It is concluded that the antiemetic effect of intravenous metoclopramide in large amounts can prevent cisplatin-induced emesis.
著者
久保 武 坂田 義治
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 補冊 (ISSN:09121870)
巻号頁・発行日
vol.1991, no.Supplement41, pp.60-66, 1991-02-05 (Released:2012-11-27)
参考文献数
30
被引用文献数
1 1

Positional alcohol nystagmus (PAN), alcoholic gaze nystagmus (AGN), trunkal ataxia and other oculomotor abnormalities are well-known behavioral changes that follow alcohol ingestion. This paper reviews previous work concerned with these alcohol-induced behavioral changes, including our recent work. We cofirmed that PAN could be elicited by even low blood alcohol concentrations (BAC was 0.02%) and two different types of the form were observed to arise chronologically (PAN I and PAN II). Moreover, a significant linear relationship was found between the intensity of PAN and BAC. When trunkal ataxia was measured with a stabilometer, the circumscribed area of body sway showed the closest correlation with BAC. Other analyses of body sway failed to find any characteristic features of alcohol-induced trunkal ataxia.
著者
松永 亨 山本 好一
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.78, no.11special, pp.2687-2692, 1985-11-25 (Released:2011-11-04)
参考文献数
14

This study was performed to determine whether electrical stimulation of the autonomic centers, that is, the medial nuclei of the hypothalamus in the diencephalon causes asymmetric per-rotational nystagmus (PRN) in healthy or sympathectomized rabbits. The superior cervical ganglion was removed on one or both sides. Asymmetric PRN occurred very rarely in normal or bilaterally sympathoectomized animals, while directional preponderance (DP) appeared in more than half of the recordings in unilaterally sympathectomized animals. Although the rise in blood pressure (BP) during the intravenous influsion of norepinephrine in unilaterally sympathectomized animals also caused significant DP (previous paper), it was less than the degree of DP appearing with the same increment of BP caused by hypothalamic stimulation. Three of 5 animals with asymmetric PRN caused by stimulation showed side differences of cerebellar oxygen tension.These findings show that asymmetric PRN following hypothalamic stimulation can be explained by a neural action on the vestibular neurons from the hypothalamus via the brainstem reticular formation or the cerebellum in addition to the asymmetric vertebral blood flow induced by symathetic vasoconstriction. We propose that this experimental model shows how psychogenic vertigo and/or dizziness can originate from distrubances of the central autonomic nervous system.
著者
簑和田 寛子
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.62, no.6, pp.735-798, 1969-06-01 (Released:2011-10-14)
参考文献数
517
被引用文献数
2
著者
城野 明子 山本 博香 久保田 功 市川 季佐子 太田 文彦
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 補冊 (ISSN:09121870)
巻号頁・発行日
vol.1991, no.Supplement45, pp.151-158, 1991-06-15 (Released:2012-11-27)
参考文献数
15

Three hundred and eighty children were diagnosed as “delayed speech and language development” at our speech clinic in Kinki University Hospital from 1977 to 1989. To investigate the language abilities and the possible causal factors of these children as a group, medical records and speech and language records including case histories of each child were reviewed and statistically analyzed.At the first referral,77 % of the children were under age 6, and 51% were between ages 2 1/2 and 4 1/2 years old. The incidence was higher for the boys than the girls at the ratio of three to one. The average onset of walking was 17 ± 8.0 months, and the average onset of speech was 20.5 ± 11.6 months. Seventy percent of the subjects were normal in their communicative manners,10% were autistic and 20% were in-between.Language abilities were evaluated by using a five level scale, which was proposed by the Committee of Delayed Speech and Language Development in the Japanese Society of Logopedics and Phoniatrics. Abilities of receptive language and of expressive language were evaluated separately. In both abilities, more than one third of the subjects were evaluated at level 3, that is, the child points at the picture card when the object shown on each card is mentioned, or a child answers the name of the object or picture shown to him.Seventy five percent of the subjects showed some kind of anomalies or deficiencies besides speech and language deficiencies. Mental retardation was seen in 43% of the subjects.
著者
荻野 敏 入船 盛弘 後藤 啓恵 仙波 治 野入 輝久
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.92, no.3, pp.309-324, 1999-03-01
参考文献数
13
被引用文献数
4

The clinical efficacy and safety of 200 &mu;g/day (100&mu;g b. i. d) of mometasone furoate nasal spray (MFNS) administered for 2 weeks was evaluated by comparison with a low dose of MFNS of 50&mu;g/day (50&mu;g o. d.) using the envelope-method in a total of 65 patients with Japanese cedar<br>pollenosis.<br>The pollen counts for Japanese cedar in 1995 were extremely high in the Kansai district. About 5, 000 counts/cmz was confirmed in and around Osaka.<br>In the analysis of final overall improvement, marked or moderate improvement was observed in 76.2% (16/21) and 20.8% (5/24) of patients receiving MFNS 200&mu;g/day and 50&mu;g/day, respectively. The difference in efficacy between the two dosage groups was confirmed independently of timing of the initiation of administration. In the analysis of overall safety, high safety was observed with both treatments. The above results suggest that 200&mu;g/day of MFNS can be considered the recommended dose for the treatment of Japanese cedar pollenosis.
著者
庄司 和彦 藤田 修治 大森 孝一 辻 純 伊藤 壽一 本庄 巖
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.81, no.12, pp.1709-1713, 1988-12-01 (Released:2011-11-04)
参考文献数
4
被引用文献数
1 1

Patients with multi-electrode cochlear implants can distinguish vowels well, but the ‘sounds’ they hear through this device are unknown. In order to simulate vowels through multielectrode cochlear implants, we synthesized waves which have translated formant frequencies using a computer and reverse fourier transformation .Through a digital-analog converter, we heard the synthesized sounds. Each sound is quite different from each vowel, but we can easily distinguish them from each other. With the use of this procedure, cochlear implants can be expected to be improved.
著者
田島 正記 武藤 二郎 滋賀 秀壮 目澤 良憲
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.88, no.12, pp.1571-1578, 1995-12-01
参考文献数
34

Prolonged vertigo and dizziness are good indications for Kampo treatment. An analytical study of the effect of Kampo-medicines on 30 patients with prolonged vertigo or dizziness was carried out, and the following results were obtained:<br>1) Every male patient was successfully cured with &ldquo;Sui&rdquo; medicine*.<br>2) Female patients more than about 70 years of age were also cured with &ldquo;Sui&rdquo; medicine.<br>3) Female patients with menstrual disorders, or uterine and ovarian diseases were cured with a combination of &ldquo;Sui&rdquo; and &ldquo;Ketsu&rdquo; medicine**.<br>4) Younger females with vertigo or dizziness at the time of menstruation were treated succesfully with &ldquo;Ketsu&rdquo; medicine only.<br>5) Patients wtih psychosomatic symptoms in addition to vertigo or dizziness required &ldquo;Ki&rdquo; medicine*** in combination with &ldquo;Sui&rdquo; or &ldquo;Ketsu&rdquo; medicine.<br>These results have contributed to finding the most effective Kampo-medicine for patients suffering from prolonged vertigo and/or dizziness.<br>*&ldquo;Sui&rdquo; medicine: medicine for regulating body fluids.<br>**&ldquo;Ketsu&rdquo; medicine: medicine for regulating blood and the water metabolism of the body.<br>***&ldquo;Ki&rdquo; medicine: medicine for regulating vital energy in the body.