著者
川瀬 哲明 洲崎 洋 高坂 知節
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.89, no.6, pp.681-685, 1996-06-01 (Released:2011-11-04)
参考文献数
18

Masking patterns for 1 kHz pure tone at 20, 40 and 60 dB SL were examined in listeners with age-related hearing impairment and in subjects with normal hearing. As has been reported, as the masking level was elevated, the masking effect increased and spread especially towards higher frequencies as well as around the masker frequency. In listeners with impaired hearing, the spread of masking effects towards the higher frequencies was significantly larger as the hearing level deteriorated. The results of the present study are thought to reflect the broader auditory filter in impaired listeners, particularly on the low frequency side.
著者
大越 俊夫
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.99, no.11, pp.891-896, 2006-11-01 (Released:2011-10-07)
参考文献数
15
被引用文献数
1

Abnormal sensations in the throat can be induced by a wide variety of causes, and therefore requires both mental and physical approaches to treatment. In addition, malignant tumors maybe detected in a small number of patients with complaints of abnormal sensations in the throat, and this must never be overlooked. While there have been numerous reports descring various tests, diagnostic methods for determining the causes of abnormal sensations in the throat as well as administration the of therapeutic drugs vary among facilities and few reports have investigated cases of abnormal sensations refractory to initial treatment. Furthermore, although the involvement of psychogenesis in this illness is not small, the extent of its involvement is extremely difficult to assess. While therapeutic determination using various psychological tests and the effects of mild tranquilizers has been attempted, clarification of the extent of psychogenic involvement in this illness remains difficult, as does the treatment of this illness as a psychosomatic illness in the field of otolaryngology.Improvement in abnormal sensations in the throat is determined by changes in the subjective symptoms of the patient. Many reports on the treatment of abnormal sensations in the throat have focused on the effects of administering a specific drug in response to a defined cause of illness, and few have reported the final improvement rates of the patients included in these studies. In other words, it is important to investigate secondary and tertiary treatment methods and the extent to which abnormal sensations in the throat has been improved in patients with abnormal sensations refractory to initial treatment, as well as the appropriate course of action when improvements are not observed.
著者
甲斐 智朗
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.95, no.7, pp.679-684, 2002-07-01 (Released:2011-11-04)
参考文献数
9
被引用文献数
1 1

Two cases of psychogenic hearing loss in adults are presented with the process of their mental states. Case 1 was a 20-year-old male who complained of unilateral hearing loss and tinnitus on his left side after receiving a “karate” kick on his left temple. Considering the perforation of his left tympanic membrane, his left hearing level was much worse (77.5 dBHL). Later examination of ABR revealed the sensorineural system to be intact, and functional hearing loss was suspected. Further questions about his history disclosed that he was extremely unhappy in his job and wanted to leave his present employment. After discussion with psychiatrists, the diagnosis of psychogenic hearing loss was established.Case 2 was a 23-year-old male who complained of right tinnitus after hearing rifle shooting during night time maneuvers in the Self Defense Forces. In spite of the normal appearances of his external and middle ear, his hearing level was 72.5dBHL. Being treated as acoustic trauma, ABR was performed and it resulted in a completely normal response. In this case, the diagnosis of psychogenic hearing loss was also established.Especially in adults, psychogenic hearing loss is regarded as a kind of conversion disorder. In this disease, getting ill brings some “gain” to the patients. Admission to the hospital separates a patient from his unpleasant job and persons (secondary gain). This is almost compatible with the mental state of case 1. When their desires are converted to physical disorders and are appreciated by another person, they don't have to be concerned by their source of annoyance. Thus their mental states are stabilized (primary gain). This is almost compatible with the mental state of case 2.When assessing patients of Psychogenic hearing loss, their mental states should be considered as there may be various processes involved in the disease.
著者
山岸 益夫 中村 英生 鈴木 正治 長谷川 聡 中野 雄一
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.83, no.3, pp.383-390, 1990-03-01 (Released:2011-11-04)
参考文献数
12
被引用文献数
1 1

Morphological and immunohistochemical examinations were performed on the olfactory mucosa of eight patients with olfactory disturbances caused by the common cold (viral infection). The results of olfactory testing and of follow-up examinations were analyzed.H. E. staining revealed three patterns of degeneration. In Group 1 (3 patients) the olfactory epithelium had adequate thickness and a basic arrangement of supporting cells, olfactory receptor cells, and basal cells, but slightly fewer than normal receptor cells. In Group 2 (3 patients) olfactory receptor cells were greatly decreased. Group 3 (2 patients) had olfactory epithelium which was thin and atrophic with no receptor cells or olfactory vesicles, and only the supporting and basal cells remained. Group 1 patients had Grade 2, Group 2 patients Grade 3, and Group 3 patients Grade 4 damage according to our classification of degeneration proposed in 1988.Immunohistochemically, neuron-specific enolase (NSE) immunoreactivity was found in a number of receptor cells in Group 1 with Grade 2 damage and in some in Group 2 with Grade 3 damage. In Group 3 with Grade 4 damage, there was no NSE-immunoreactivity in the epithelium. Glia-specific S-100 protein immunoreactivity was found in Bowman's glands and olfactory nerve bundles in the lamina propria of Group 1 and 2 patients with Grade 2 and 3 damage. Cytokeratin immunoreactivity was found in the basal cells on the basement membrane in all three groups.Seven patients were found to be anosmic with T & T olfactometry, but the three patients in Group 1 responded well to Alinamin- intravenous injection test, and two of them recovered.These results indicate that there is a strong relationship among the appearance of the olfactory epithelium, results of the Alinamin- test and the outcome of olfactory disturbance caused by the common cold. When an olfactory mucosall biopsy performed at the first visit of the patient shows enough functional receptor cells and the Alinamin- test is positive, it is possible that the olfactory disturbance may improve.
著者
原田 康夫 夜陣 紘治 平川 勝洋 中田 将風 竹林 脩文 築家 大介 黒川 道徳 村上 譲 菊屋 義則 野田 益弘 二宮 優子 笹 征史
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.79, no.1, pp.161-172, 1986-01-01 (Released:2011-11-04)
参考文献数
15
被引用文献数
1

Patients with pharyngitis and tonsillitis were studied in a randomized double-blind trial to compare the clinical usefulness of MK212G and Isodine gargle.1. Of the 71 patients treated with MK212G or Isodine gargle, four were excluded because they were out of protocol. The results in the remaining 32 patients treated with MK212G and 35 patients treated with Isodine gargle were analyzed statistically.2. MK212G was effective in 93.8% and Isodine gargle in 85.7%, not a statistically significant difference (x2=3.807 N.S.).3. In the MK212G group, one patient complained of oral discomfort and in the Isodine gargle group, two patients had mild nausea and one had vomitting. The difference was not statistically significant (x2=1.165 N. S.).4. MK212G was considered to be clinically useful in 87.51% and Isodine gargle in 82.86%, not a statistically significant difference (x2=0.410 N. S.).5. The above results suggest that MK212G is as useful as Isodine gargle in the treatment of pharyngitis and tonsillitis.
著者
丘村 煕
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.68, no.7, pp.919-935, 1975-07-01 (Released:2011-11-04)
参考文献数
33
被引用文献数
2 2
著者
牛尾 信也
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.64, no.7, pp.699-711, 1971-07-01 (Released:2011-10-14)
参考文献数
20
被引用文献数
2 2
著者
大島 昭夫
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.99, no.8, pp.643-646, 2006-08-01 (Released:2011-10-07)
参考文献数
15
被引用文献数
1 1

Patent eustachian tube patients are becoming increasingly rare.I proposed to classify these patients into a lighter grade I to severe grade III, according to their symptoms and examinations findings and used this to decide on an appropriate therapy.Grade I: Fullness of the ear. No finding in the tympanic membrane during Toynbee's maneuver.Therapy·Administer the Chinese medicine KAMIKIHITO. Pour a mixture of jel-foam, glycerin and 0.9% saline solution into the eustachian tube.Grade II: Grade I plus autophonia and tympanic membrane movement during Toynbee's or Valsalva's maneuver.Therapy·In addition to that proposed for Grade I, submembranous injection of dimethyl polysiloxan or aterocollagen into the nasopharyngeal tubal orifice.Grade III: Most severe case.Therapy·In addition to that proposed for Grade II, insertion of KOBAYASHI's eustachian tube pin into the tympanic orifice of the eustachian tube.
著者
佐藤 宏昭 中村 一 本庄 巖 藤田 明彦 高橋 晴雄 林 正彦
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.81, no.9, pp.1383-1387, 1988-09-01 (Released:2011-11-04)
参考文献数
10
被引用文献数
2 6

The clinical usefulness of Tsumura-Saireito, which was judged by tympanoaudiometric tests, was compared with that of cepharanthin in 64 ears of 42 children with otitis media with effusion. The trial was a randomized controlled study.The efficacy rate for the 32 ears treated with Tsumura-Saireito was 43.8% and that for the 32 ears treated with Cepharanthin was 18.8%; the difference was significant (p<0.05). No side effects were observed in either group.These results indicate that Tsumura-Saireito is more effective in children with otitis media with effusion than Cepharanthin.
著者
佐藤 斎 大滝 一 藤崎 俊之 中野 雄一
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.89, no.11, pp.1319-1322, 1996-11-01 (Released:2011-11-04)
参考文献数
8
被引用文献数
1 1

Two cases of psychogenic hearing loss combined with psychogenic aphonia are reported.Case one was a 15-year-old female with psychogenic hearing loss that appeared just before taking a high school entrance examination. After she passed the examination, the complaint of hearing loss was reduced. Three years later she suddenly suffered from psychogenic aphonia prior to taking a college entrance examination. The aphonia also diminished after she passed the examination. Both the hearing loss and aphonia were attributed to the stress caused by the entrance examinations.Case two was a 26-year-old female who suddenly suffered from profound hearing loss and aphonia simultaneously. The conditions were brought on apparently by a psychogenic reaction to a stressful relationship with her mother-in-law.In both cases, the threshold of auditory brain stem evoked response was normal while the threshold of pure tone audiogram indicated profound sensorineural hearing loss. The phonolaryngogram was useful for diagnosis and evaluation of voice disturbance.
著者
清水 弘
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.48, no.9, pp.635-653, 1955 (Released:2011-10-14)
参考文献数
18
被引用文献数
1 2
著者
三上 慎司 上條 朋之 小泉 敏三 福田 多介彦 家根 旦有 細井 裕司
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.101, no.2, pp.147-151, 2008-02-01 (Released:2011-10-07)
参考文献数
16

White lesions in the larynx, pharynx, and oral regions, which are called leukoplakias clinically, show a variety of histopathological features, including hyperplasia, dysplasia and cancer. Therefore, they should be treated carefully as precancerous lesions. Eighty-one patients with leukoplakia of the larynx, pharynx and oral tissue were treated between 1996 and 2005.The majority of these patients with leukoplakia in the larynx were heavy smokers.In the 11 cases of leukoplakia in the larynx, the white lesions were resolved by conservative treatment. Based on the findings above, it is important for heavy smokers to stop smoking completely. In leukoplakia of the larynx, squamous cell carcinoma was detected in 15 cases (26.8%).In leukoplakia of the oral tissue and pharynx, squamous cell carcinoma was detected in 2 (8.0%).Among the 81 cases in this series, squamous cell carcinoma was detected in 6 laryngeal lesions and 1 oral and pharyngeal lesions. Histological findings of these lesions were all dysplasia, initially. Therefore, long term follow-up is recommended if the histologoical findings of leukoplakia initially demonstrate dysplasia.
著者
卜部 信行
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.78, no.8special2, pp.1731-1745, 1985-08-24 (Released:2011-11-04)
参考文献数
32

Cases of tinnitus totaling up to 163 examined at the Oto-Rhino-Laryngological Clinic of Tottori University Hospital have been reviewed. They consisted of 78 men and 85 women aged from 15 to 84 years. Tinnitus was attempted to be expressed verbally by onomatopoeia. The most frequent expression was “geen” [d i n]. Pitch matching and loudness matching tests were carried out in 146 patients. The most frequently observed pitch and loudness of tinnitus was 8000Hz and 0dB HL., respectively. The masking curve examined by bands of noise showed 7 types, including the convergence type (42% of 77 cases). Residual inhibition (RI) was studied by 1-min delivery of bands of noise in 82 cases, in 58 of which RI was positive. Effects of i. v. injected lidocaine (60mg for males, 40mg for females) were examined in 121 cases: tinnitus disappeared entirely in 39 cases; and was reduced partially in 53. The i. v. injected agent was effective in most of the RI-positive cases. To sum up these findings and ones obtained by auditory brain-stem response examination, suppression of tinnitus by RI and i. v. injected lidocaine may result from participation in the brain stem.
著者
調所 廣之
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.85, no.1, pp.21-23, 1992-01-01 (Released:2011-11-04)
参考文献数
4
被引用文献数
1
著者
立木 孝
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.58, no.11, pp.741-751, 1965-11-01 (Released:2011-10-14)
参考文献数
31
著者
馬越 智浩 高橋 廣臣 八尾 和雄 稲木 勝英 中山 明仁 永井 浩巳 岡本 牧人
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.94, no.1, pp.65-69, 2001-01-01 (Released:2011-11-04)
参考文献数
18

Between June 1988 and December 1996, 57 patients with non-Hodgkin's lymphomas of the head and neck were treated at our department. The primary lesion was located in Waldeyer's ring in 31 patients and cervical lymph nodes in 26 patients. These patients, who were diagnosed as Stage I or II, were treated with chemotherapy and radiation. The chemotherapy regimen consisted of pirarubicin (45mg/m2; day 1), cyclophosphamide (750mg/m2; dayl), vindesine (1.5mg/m2; day 1) and predonisolone (100mg/body; days 1-5). The complete and partial response rates were 79% and 82% respectively. The five-year estimated overall survival rate calculated by Kaplan-Meier method was 75%. We concluded that the combination of chemotherapy regimen (THP-CVP) and radiation were useful and safe for treating non-Hodgkin's lymphomas of the head and neck.
著者
水田 啓介 伊藤 八次 西田 基 秋田 茂樹 加藤 雅也 小塩 勝博 海田 健宏 古田 充哉 宮田 英雄 柳田 正巳 柴田 康成 横山 壽一 松原 茂規 小泉 光 森 芳郎 大野 通敏 近藤 由香 藤宮 大 山田 匡彦 渡辺 英彦 加藤 洋治
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.90, no.12, pp.1399-1407, 1997-12-01 (Released:2011-11-04)
参考文献数
14

IPD® (supratast tosilate) was investigated for its prophylactic efficacy and therapeutic efficacy in the treatment of cedar pollinosis during the 1996 cedar pollen season. The subjects investigated were patients at the Gifu University School of Medicine and its affiliated hospitals, who had a history of cedar pollinosis. The patients were classified into two treatment groups: the prophylaxis group (70 patients), in whom IPD® administration began before the start of cedar pollen dispersion, and the treatment group (49 patients), who underwent IPD® treatment only after cedar pollen dispersion had begun and symptoms of pollinosis had manifested.Results were as follows: (1) The nasal symptoms (sneezing, runny nose, nasal congestion) were milder in the prophylaxis group than in the treatment group throughout the cedar pollen season, with the difference being significant during the season's first 2 weeks. (2) In the prophylaxis group, IPD®'s inhibitory effect was rated as excellent in 18.6% of the patients, good in 45.7% and fair in 20.0%. In the treatment group, the improvement in the symptoms was rated as disappearance in 4.2%, excellent in 20.8% and good in 43.8%. (3) When symptom inhibition in the prophylaxis group was investigated as a function of the duration of IPD® administration prior to the start of pollen dispersion, the good + excellent inhibition rate was 57.7% in the subpopulation pretreated for <2 weeks (26 cases), 64.9% with 2 to <4 weeks' pretreatment (37 cases) and 85.7% with 4 to <6 weeks' pretreatment (7 cases). Thus, IPD®'s prophylactic inhibitory rate increased with the length of the pretreatment period. (4) In the prophylaxis groups, the CAP-RAST value was significantly reduced at the time of peak pollen level and at the end of the pollen season compared with the value before IPD® administration.