著者

小関 健 羽根田 達史

出版者

一般社団法人電子情報通信学会

雑誌

電子情報通信学会総合大会講演論文集

巻号頁・発行日

vol.2007, 2007-03-07

著者

大野 隆一郎

出版者

地学団体研究会

雑誌

地学教育と科学運動 (ISSN:03893766)

巻号頁・発行日

no.70, pp.94-96, 2013-07-25

著者

水野 知昭

出版者

信州大学人文学部

雑誌

人文科学論集 文化コミュニケーション学科編

巻号頁・発行日

vol.34, pp.89-114, 2000-03-15

著者

村山 高章 松本 あさひ 森崎 市治郎

雑誌

障害者歯科 (ISSN:09131663)

巻号頁・発行日

vol.30, no.3, 2009-09-30

著者

成川 日女美

出版者

文学教育研究者集団

雑誌

文学と教育 (ISSN:02876205)

巻号頁・発行日

no.192, pp.34-38, 2001-08-03

著者

片岡 邦光

出版者

日本結晶学会

雑誌

日本結晶学会誌 (ISSN:03694585)

巻号頁・発行日

vol.54, no.Supplement, pp.s5-s6, 2012-10-25 (Released:2012-12-01)

著者

坂田 俊子

出版者

日本小児医事出版社

雑誌

小児科臨床 (ISSN:0021518X)

巻号頁・発行日

vol.59, no.5, pp.1045-1050, 2006-05

著者

小川 桂一郎

出版者

日本結晶学会

雑誌

日本結晶学会誌 (ISSN:03694585)

巻号頁・発行日

vol.38, no.6, pp.363-377, 1996-12-30 (Released:2010-09-30)

参考文献数

5

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How to create and use CIF, which is required for submission of papers having the results of crystallographic structure analysis, is illustrated.

著者

森本 邦生

出版者

日本武道学会

雑誌

武道学研究 (ISSN:02879700)

巻号頁・発行日

vol.47, no.3, pp.139-146, 2015-03-31 (Released:2016-03-31)

著者

LESLEY J COLLINS PATRICK J BIGGS CLAUDIA VOELCKEL SIMON JOLY

出版者

日本バイオインフォマティクス学会

雑誌

Genome Informatics (ISSN:09199454)

巻号頁・発行日

vol.21, pp.3-14, 2008 (Released:2011-07-11)

参考文献数

10

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Transcriptome analysis using high-throughput short-read sequencing technology is straightforward when the sequenced genome is the same species or extremely similar to the reference genome. We present an analysis approach for when the sequenced organism does not have an already sequenced genome that can be used for a reference, as will be the case of many non-model organisms. As proof of concept, data from Solexa sequencing of the polyploid plant Pachycladon enysii was analysed using our approach with its nearest model reference genome being the diploid plant Arabidopsis thaliana. By using a combination of mapping and de novo assembly tools we could determine duplicate genes belonging to one or other of the genome copies. Our approach demonstrates that transcriptome analysis using high-throughput short-read sequencing need not be restricted to the genomes of model organisms.

出版者

ポット出版

雑誌

ず・ぼん

巻号頁・発行日

no.13, pp.4-37, 2007-11

出版者

国立国会図書館

巻号頁・発行日

1961

著者

宮崎郁雨著

出版者

東峰書院

巻号頁・発行日

1960

著者

大森 一彦

出版者

関西大学国文学会

雑誌

国文学 (ISSN:03898628)

巻号頁・発行日

no.51, pp.p64-72, 1975-06

著者

Sayoko Kinoshita Kyoichi Wada Sachi Matsuda Takeshi Kuwahara Haruki Sunami Takuma Sato Osamu Seguchi Masanobu Yanase Takeshi Nakatani Mitsutaka Takada

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.55, no.7, pp.719-724, 2016 (Released:2016-04-01)

参考文献数

25

被引用文献数

2 4

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Objective The purpose of this study was to investigate the possible interaction between warfarin and linezolid in patients with a left ventricular assist system (LVAS) for the treatment of severe heart failure. Methods Patients with LVAS who were treated with linezolid for the treatment of infections from January 2003 to March 2013 were identified from medical records. The impact of linezolid on the clotting function, as well as the dose of warfarin during the first 10 days of linezolid therapy, was investigated. The mean prothrombin time-international normalized ratio (PT-INR) and mean doses of warfarin during 7 days before and 10 days after the initiation of linezolid therapy were calculated for individual patients. The PT-INR per mg of WF dose on the previous day (X) was calculated. The warfarin dose, PT-INR, and warfarin sensitivity index (WSI) value before and after the initiation of linezolid were compared to evaluate the impact of linezolid on the effect of warfarin. Results Sixteen patients were enrolled in the study. Although the mean PT-INR increased from 3.74 to 4.06, no significant difference was observed (p=0.05). A significant difference was observed in the mean dose of warfarin before and after the initiation of linezolid administration, with a decrease from 3.23 to 2.69 mg/day (p=0.001). In contrast, the mean WSI value significantly increased from 1.37 to 1.82 (p=0.014). After 10 days of linezolid administration, the mean X values increased over the baseline value by 31.7%. Conclusion These findings suggest that co-administration of linezolid results in increased PT-INR in patients with LVAS treated with warfarin.

著者

Junya Hashizume Norihide Higuchi Kayoko Sato Yukinobu Kodama Noriko Matsunaga Toshiaki Sakamoto Kentaro Yamaguchi Tadahiro Nakamura Takashi Kitahara Hitoshi Sasaki

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.39, no.4, pp.611-614, 2016-04-01 (Released:2016-04-01)

参考文献数

21

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Antiemetic prophylaxis with aprepitant, a 5-hydroxytryptamine3 (5-HT3) receptor antagonist and dexamethasone is recommended for patients receiving intravenous cisplatin chemotherapy. Whether the same antiemetic regime is superior for hepatic transcatheter arterial infusion chemotherapy with cisplatin (CDDP-TAI) is unknown. We conducted a retrospective study of antiemetic prophylaxis protection against chemotherapy-induced nausea and vomiting (CINV) in CDDP-TAI at Nagasaki University Hospital. The rate of complete response (CR) to antiemetics in the acute (<24 h) and delayed phases (24–120 h) was measured. Twenty-four patients were treated with a 5-HT3 receptor antagonist (granisetron or azasetron) and dexamethasone on the day of chemotherapy (day 1 only). There was a significant difference between the CR rates in the acute and delayed phases, 91.6, and 69.7%, respectively. Combination of a 5-HT3 antagonist and dexamethasone on day 1 is effective against acute CINV, but not delayed CINV during CDDP-TAI. These results may help guide the management of nausea and vomiting during CDDP-TAI to achieve better tolerance and compliance for fewer interventions and increased favorable therapeutic outcomes.

著者

Yasuhisa Izushi Yoichiro Takami Naofumi Shiota Tomonori Tetsunaga Yusuke Ookura Kenichi Shimada Takashi Egawa Tsukasa Kiuchi Toru Sato Ritsugi Takuma

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.39, no.4, pp.516-523, 2016-04-01 (Released:2016-04-01)

参考文献数

20

被引用文献数

5

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Edoxaban, an oral direct factor Xa inhibitor, was developed and approved for anticoagulant thromboprophylaxis after total knee arthroplasty (TKA). We retrospectively investigated the postoperative anemia by oral administration of edoxaban 30 mg compared with fondaparinux 2.5 mg in TKA patients. Two hundred twenty nine patients who underwent TKA in National Hospital Organization Okayama Medical Center from July 2010 to June 2012 were divided into two groups; pre and post approval of edoxaban: fondaparinux-group (F-group) and edoxaban-group (E-group). As the primary endpoint, the frequency of postoperative anemia was evaluated. Blood coagulation values and relations between these parameters and postoperative anemia were also investigated. The frequency of postoperative anemia was significantly higher in E-group than F-group patients (52.7% vs. 37.8%; p<0.05). Hemoglobin (Hgb) levels were decreased with the peak at postoperative day (POD) 3 in both groups, and the change of Hgb values from POD1 (ΔHgb) was significantly increased in the E-group (p=0.04). At each POD, prothrombin time (PT) and international normalized ratio of PT (PT-INR) prolonged from the preoperative day in E-group were significantly higher than F-group. Additionally, PT and PT-INR in the E-group at POD3 were significantly prolonged in patients with postoperative anemia and the sensitivity of cut-off values to predict postoperative anemia was superior to the activated partial thromboplastin time (APTT). Thus, as the frequency of postoperative anemia tended to be higher in E-group, edoxaban 30 mg might require vigilance, and prolonged PT and PT-INR could potentially predict edoxaban-associated postoperative anemia after TKA.

著者

桑田 秀夫

出版者

社団法人 日本繊維機械学会

雑誌

繊維工学 (ISSN:18838731)

巻号頁・発行日

vol.19, no.6, pp.P459-P466, 1966-06-20 (Released:2010-09-27)

著者

小口 峰樹

出版者

総合文化研究科広域科学専攻

巻号頁・発行日

2013-06-27

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学位の種別: 課程博士

著者

森川 知史

出版者

九州龍谷短期大学

雑誌

九州龍谷短期大学紀要 (ISSN:09116583)

巻号頁・発行日

vol.37, pp.57-86, 1991-03-20