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1 0 0 0 顆粒膜細胞腫に罹患した雌馬の内分泌動態

著者: 吉田剛角田修男三宅陽一シャフィクルホーク大澤健司長嶺夏子谷山弘行南保泰雄渡辺元田谷一善
出版者: 日本ウマ科学会
雑誌: Journal of equine science (ISSN:13403516)
巻号頁・発行日: vol.11, no.2, pp.35-43, 2000-06-01
参考文献数: 24
被引用文献数: 1

2021-01-15 17:30:08
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https://ci.nii.ac.jp/naid/10027044124

1 0 0 0 受注状況「総合」は厳しく,「専門」が優位に (特集建築界2002 設計事務所編もう通用しない"何でも受注"シフト)

出版者: 日経BP社
雑誌: 日経ア-キテクチュア (ISSN:03850870)
巻号頁・発行日: no.728, pp.70-73, 2002-09-30

s大手事務所の売上高が引き続き減少する一方で,専門事務所が売上高を維持する傾向が鮮明になってきた。s専門事務所が優位な状況は,コンペ・プロポーザルの当選確率などの受注活動にも表れている。s大手事務所の中には,「チーフ・アーキテクト制」など顔の見える組織に改変する動きも出始めている。大手事務所の売上高がどこまで落ち込みむのか,底が見えない——。

2021-01-15 17:15:05
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https://ci.nii.ac.jp/naid/140000030881

1 0 0 0 OA 成長期におけるソフトフード摂取がラット顎関節に与える影響

著者: 加藤剛士
出版者: 北海道大学
巻号頁・発行日: 2014-03-25

Modern people tends to have soft food . Therefore experimentalstudies have been performed to examine unfavorable influences to growth ofmasticatory muscles and craniofacial bone induced by such a dietary habits.The aim of the present study was to clarify the effects of soft diet on thetemporomandibular joint (TMJ) in growing rats using thehistomorphometrical and immunohistochemical methods. Twenty-four maleWistar rats were weaned at age 21 days and were divided into control andexperimental groups. Control rats were fed a solid food and experimentalones fed a liquid food from 1 to 8 weeks. After injection with5-bromo-2’-deoxyuridine (BrdU), the animals were perfused with 4%paraformaldehyde solution and the whole heads were removed. Serialcoronal sections of TMJ were stained with Haematoxylin and Eosin or withBrdU-immunohistochemistry. Three dimensions and the thickness ofcartilage layer of the TMJ were measured using histological sections, andcell proliferation in the TMJ was examined using immunostained sections.The height and width of the zygomatic process of mandibular fossa inexperimental group were smaller than in control group after 4 weeks. Thewidth and length of the condyle of experimental animals were also smallerthan those of controls after 4 weeks. In the mandibular fossa, articular zone(AZ) and hypertrophic zone (HZ) at 4 weeks and AZ and intermediate zone(IZ) at 8 weeks in the experimental groups were thinner than in the control.All zones at 4 weeks and AZ at 8 weeks of the condyle in the experimentalgroup were also thinner. The labeling indices of BrdU in IZ of themandibular fossa and of the condyle in the experimantal groups were lowerthan in the controls at 4 weeks and at 1 and 4 weeks, respectively. Thesefindings suggest that the soft food-intake inhibits the growth of the TMJ ofrats, due to low proliferative activity of cells in IZ.