文献一覧: 岡田靖 (著者)

Hypertension is the major risk factor for stroke. In the Hisayama study, the risks of cardiovascular disease increased significantly from the lower range (120–129/80–84 mmHg) of prehypertension in a general Japanese population. Since the clinical trial SPRINT demonstrated that targeting a systolic blood pressure of less than 120mmHg reduced fatal and nonfatal major cardiovascular events, blood pressure goals in patients with hypertension currently tend to be more intensive. However, we should conduct more careful antihypertensive treatment when setting blood pressure target in the elderly or patients with cerebral artery stenosis. The meta–analysis including the majority studies for primary stroke prevention has shown that reducing LDL cholesterol with statins reduces the risk of stroke, therefore statin therapy is recommended for patients with dyslipidemia, especially having diabetes mellitus. Early detection and treatment of atrial fibrillation are valuable prevention for stroke risk reduction in the elderly. Anticoagulation should be considered even for the patients with atrial fibrillation (CHADS2 0 or 1) and other vascular risk factors. Regarding primary prevention of stroke for patients with asymptomatic cerebral atherosclerosis and silent lacunar infarction, intensive management of vascular risk factors such as hypertension and diabetes mellitus is the most important treatment for stroke prevention, and antiplatelet therapy should be taken into considered only in patients with high risk of ischemic stroke.It is also essential to educate and enlighten the knowledge of stroke risk factors and warning signs to the general public.

2023-02-05 17:56:45
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1 0 0 0 OA 4.転倒や出血を考慮した抗血栓薬管理

著者: 杉森宏森興太矢坂正弘岡田靖
出版者: 一般社団法人日本老年医学会
雑誌: 日本老年医学会雑誌 (ISSN:03009173)
巻号頁・発行日: vol.59, no.3, pp.305-311, 2022-07-25 (Released:2022-09-07)
参考文献数: 14

高齢者では転倒・転落による死亡者数は不慮の事故の中で最も多い.抗血栓療法は循環器疾患をそしてそれに伴う転倒も予防するが,同時に出血を宿命的に合併する.転倒は患者側の原因と環境原因が重なって起こることを認識してリスクを評価し,転倒リスクに関連する薬剤の処方などを抑制する.また適応があるなら新規経口抗凝固薬などより安全な薬剤を処方し,極端に虚弱な患者には抗血栓療法を控えることも考慮するなど総合的な対応が重要である.

2022-09-07 13:32:00
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1 0 0 0 OA 地球温暖化予測における梅雨期の降水および大気場の変化

著者: 岡田靖子竹見哲也石川裕彦楠昌司水田亮
出版者: 京都大学防災研究所
雑誌: 京都大学防災研究所年報. B (ISSN:0386412X)
巻号頁・発行日: vol.58, no.B, pp.157-161, 2015-06

This study focuses on atmospheric circulation fields during the baiu in Japan with global warming under the RCP scenarios. We use projection experimental data conducted using a 20km-, 60km-mesh global atmospheric model (MRI-AGCM3.2). The baiu front indicated by the north-south gradient of moist static energy moves northward in present-day climate, whereas this northward shift in future climate simulations is very slow during May and June. In future late baiu season, the baiu front stays in the northern part of Japan even in August. As a result, the rich water vapor is transported around western Japan and the daily precipitation amount will increase in August. In the mid-troposphere, the horizontal warm advection roughly corresponds to upward vertical pressure velocity, and shows northward migration as seen in the lower troposphere. Especially, the RCP 8.5 scenario is delayed compared to the RCP 4.5 scenario. This tendency is evident in the north-south term of 500-hPa warm advection in particular. In conclusion, a late of the baiu rainfall band northward and an increase in precipitation during late of the baiu season are apparent from the point of view of atmospheric fields.

2021-07-07 19:15:00
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http://hdl.handle.net/2433/210078

1 0 0 0 憑きものの現象論 - その構造分析 - (上)

著者: 岡田靖雄
出版者: 日本医史学会
雑誌: 日本医史学雑誌 (ISSN:05493323)
巻号頁・発行日: vol.44, no.1, pp.3-25, 1998-03-20

2021-07-06 18:57:10
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https://ci.nii.ac.jp/naid/10006591976

1 0 0 0 Kluever‐Bucy症候群を呈した単純ヘルペス脳炎症例報告および文献的検討

著者: 岡田靖山口武典田代幹雄峰松一夫緒方絢
出版者: 一般社団法人日本内科学会
雑誌: 日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日: vol.76, no.8, pp.1294-1299, 1987

36才,男性.頭痛,発熱,意識障害,けいれんで発症し,入院時(8病日),体温38.2°C,傾眠状態,顔貌無欲状,項部硬直あり. CT上,両側側頭葉に不整形の低吸収域を呈し,血清抗体価(CF法)も有意の上昇(4→512倍)を示し,単純ヘルペス脳炎(HSE)と診断した.昏迷状態から約4カ月間,ほとんど無言無動状態で経過した.しかし, 120病日前後より発語がみられ,経口摂取,四肢麻痺の軽減など著しい改善とともに,口唇傾向,食行動異常,性欲亢進,情緒変化がみられ, Klüver-Bucy症候群(KBS)を呈した. HSE生存患者の長期的観察および看護の重要性を強調するとともに, HSEに合併したKBSについて文献的考察を加えた.