著者
Kentaro YOSHII Keita MOTTATE Yuki OMORI-URABE Yumiko CHIBA Takahiro SETO Takahiro SANADA Junko MAEDA Mayumi OBARA Shuji ANDO Naoto ITO Makoto SUGIYAMA Hiroshi SATO Hiroshi FUKUSHIMA Hiroaki KARIWA Ikuo TAKASHIMA
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.1010260371, (Released:2010-11-02)
被引用文献数
22 25

Tick-borne encephalitis virus (TBEV) is a zoonotic agent causing severe encephalitis in humans. Rodent species which are potential hosts for TBEV are widely distributed in various regions in Japan. In this study, we carried out large-scale epizootiological surveys in rodents from various areas of Japan. A total of 931 rodent and insectivore sera were collected from field surveys. Seropositive rodents against TBEV were found in Shimane Prefecture in Honshu, and in several areas of Hokkaido Prefecture. These results emphasize the need for further epizootiological and epidemiological research of TBEV and preventive measures for emerging tick-borne encephalitis in Japan.
著者
Alima DORZHIEVA Makoto NAKATA Keisuke TAKANO Youki FUJIHIKO Yasuo ITO Kiyoshi AKAHARA Katsuyoshi TACHIKAWA Yasuko ICHIMURA Yaeko FURUKAWA Hiroshi SATO Mikiko FUJISAWA Mika OKAMOTO Takehiko SHIMIZU
出版者
The Ornithological Society of Japan
雑誌
ORNITHOLOGICAL SCIENCE (ISSN:13470558)
巻号頁・発行日
vol.19, no.1, pp.41-53, 2020 (Released:2020-01-30)
参考文献数
45
被引用文献数
2

Changes in the timing of bird migration in spring and autumn in a coastal forest near the city of Niigata, central Honshu, Japan, were analyzed based on 27 years of bird-banding records. Half of the bird species studied, including all migratory types except residents, arrived or departed significantly earlier in spring due to an increase in spring temperatures. The rate of change we observed in spring migration timing due to changes in temperature was identical to or slightly greater than those reported in studies from other countries. The spring arrival of the Narcissus Flycatcher Ficedula narcissina and the Japanese Thrush Turdus cardis, both long-distance summer migrants to the nearby mountains, became earlier (advanced), however, for reasons that remained unclear. Median capture date in autumn was significantly associated with year for five species. Of these, the median capture date of the Japanese White-eye Zosterops japonicus, a resident and wandering bird, and the Black-faced Bunting Emberiza spodocephala, a wandering bird, advanced annually, while for the Japanese Robin Luscinia akahige and two other species (all long-distance migrants), it was delayed. We hypothesize that forest succession from a simple pine forest to a mixed forest with well-developed sub-canopy and shrub layers may have strongly influenced the Japanese White-eye and the Black-faced Bunting due to changes in population structure in the study area, resulting in an earlier median autumn capture date. Forest succession may also have influenced the Japanese Robin's food resources, enabling it to stay longer in the study area and resulting in a delay in autumn departure date. Thus, changes in bird migration timing differ according to different environmental factors in spring and autumn.
著者
Fumiko Tomiyama Ryu Watanabe Hiroshi Fujii Yukiko Kamogawa Yoko Fujita Yuko Shirota Takashi Nakamichi Hiroshi Sato Tomonori Ishii Hideo Harigae
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.54, no.11, pp.1427-1432, 2015 (Released:2015-06-01)
参考文献数
18
被引用文献数
6

A 71-year-old man was admitted to our department due to arthralgia and renal dysfunction. A physical examination disclosed swelling of the right shoulder and left wrist joints. Laboratory tests showed elevated serum IgG4 and creatinine levels, and magnetic resonance imaging of the wrist revealed bone erosion and synovitis. In addition, fluorodeoxyglucose positron emission tomography showed uptake in the submandibular glands, pancreas, kidneys, and affected joints and a renal biopsy revealed tubulointerstitial nephritis with the infiltration of IgG4+ plasma cells. The patient was subsequently diagnosed with IgG4-related disease (IgG4-RD) and successfully treated with corticosteroid therapy. This case suggests that erosive arthritis may occur in patients with IgG4-RD.
著者
Yusuke Konta Eiichiro Saito Koji Sato Kyohei Furuta Kenichiro Miyauchi Akiko Furukawa Hiroshi Sato Tae Yamamoto
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.61, no.21, pp.3239-3243, 2022-11-01 (Released:2022-11-01)
参考文献数
18
被引用文献数
7

We herein report a case of acute kidney injury (AKI) due to tubulointerstitial nephritis (TIN) after starting empagliflozin in a diabetic patient. The patient developed stage 1 AKI with proteinuria and elevated tubulointerstitial markers. A renal biopsy showed acute TIN with lymphocytic infiltration into the interstitium. The patient's renal function improved after discontinuation of empagliflozin and steroid administration. Sodium-glucose cotransporter 2 (SGLT2) inhibitor-induced AKI has been reported, but the underlying mechanism remains unclear, potentially because few patients with SGLT2-inhibitor-induced AKI have undergone a renal biopsy. We report the present case in the hope that it will help clarify the mechanism.
著者
Hiroshi SATO
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.72, no.12, pp.1551-1555, 2010 (Released:2010-12-29)
参考文献数
21
被引用文献数
4 4

To clarify the significance of fecal trimethylamine, lactate and volatile fatty acids (VFAs) in fermentative development of the hindgut in neonatal calves and the occurrence of diarrhea, 143 fecal samples (47 diarrheic, 93 normal and 3 meconium) were collected from 58 dairy calves fed milk. An additional 20 fecal samples were obtained from 10 weaned calves aged 13 to 18 weeks. Fecal pH, trimethylamine, ammonia, lactate and VFAs were analyzed. Compared with weaned calves, the trimethylamine level was higher in milk-fed calves and was associated with a large number of cases of diarrhea, but it had little relationship with the fecal ammonia level. Feces collected from the youngest (<2 weeks age) calves were more acidic and were associated with a higher lactate concentration. Lactic fermentation and fecal acidity were tremendously accelerated, particularly in diarrhea. Despite large fluctuations, the VFA concentrations were lower in diarrheic than in normal feces. In diarrheic feces at the youngest stage, the lower proportion of n-butyrate in the VFAs was accompanied by the elevated proportion of acetate. However, the fermentative differences between the diarrheic and normal feces were less apparent with advancing age. Thus, the fecal lactate and VFA profiles revealed marked changes with advancing age and suffering from diarrhea. Upon comparison with weaned calves, the trimethylamine level was clearly higher in the milk-fed calves and showed huge elevations in diarrheic cases.
著者
Ryu Shutta Daisaku Nakatani Yasuhiko Sakata Shungo Hikoso Hiroya Mizuno Shinichiro Suna Tetsuhisa Kitamura Katsuki Okada Tomoharu Dohi Takayuki Kojima Bolrathanak Oeun Akihiro Sunaga Hirota Kida Hiroshi Sato Masatsugu Hori Issei Komuro Masami Nishino Yasushi Sakata on behalf of the Osaka Acute Coronary Insufficiency Study (OACIS) Investigators
出版者
The Japanese Circulation Society
雑誌
Circulation Reports (ISSN:24340790)
巻号頁・発行日
vol.2, no.5, pp.280-287, 2020-05-08 (Released:2020-05-08)
参考文献数
25
被引用文献数
1

Background:Studies comparing the cardiac consequences of hydrophilic and lipophilic statins in experimental and clinical practice settings have produced inconsistent results. In particular, evidence focusing on diabetic patients after acute myocardial infarction (AMI) is lacking.Methods and Results:From the Osaka Acute Coronary Insufficiency Study (OACIS) registry database, 1,752 diabetic patients with AMI who were discharged with a prescription for statins were studied. Long-term outcomes were compared between hydrophilic and lipophilic statins, including all-cause death, recurrent myocardial infarction (re-MI) and admission for heart failure (HF) and a composite of these (major adverse cardiac events; MACE). During a median follow-up period of 1,059 days, all-cause death, non-fatal re-MI, admission for HF, and MACE occurred in 95, 89, 112 and 249 patients, respectively. Although there was no significant difference between statins in the risk of all-cause death, re-MI and MACE, the risk of HF admission was significantly lower in patients with hydrophilic than lipophilic statins before (adjusted hazard ratio [aHR], 0.560; 95% CI: 0.345–0.911, P=0.019) and after (aHR, 0.584; 95% CI: 0.389–0.876, P=0.009) propensity score matching. Hydrophilic statin use was consistently associated with lower risk for HF admission than lipophilic statins across the subgroup categories.Conclusions:In the present diabetic patients with AMI, hydrophilic statins were associated with a lower risk of admission for HF than lipophilic statins.
著者
Yuki Chiba Kei Takahashi Rui Makino Mai Yoshida Yuji Oe Tasuku Nagasawa Hiroshi Sato Mariko Miyazaki Koji Okamoto
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.8385-21, (Released:2021-12-28)
参考文献数
21
被引用文献数
1

We herein report a case of crescentic glomerulonephritis associated with infective endocarditis (IE). A 61-year-old-woman presented with a fever and renal dysfunction and was diagnosed with IE. The patient was positive for PR3-ANCA and anti-GBM antibodies. Renal biopsy findings showed crescentic glomerulonephritis with isolated deposition of C3c, a serum conversion product of complement C3. Given these clinical findings, the patient was diagnosed with IE-associated glomerulonephritis. Antibiotic therapy was continued without immunosuppressive agents. After the initiation of the antibiotics, the fever resolved, and the renal function gradually recovered. This case highlights the notion that laboratory findings should be carefully evaluated with reference to other findings.
著者
Hiroshi SATO Haruo KAMIYA Hidefumi FURUOKA
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.65, no.4, pp.453-457, 2003 (Released:2003-05-02)
参考文献数
25
被引用文献数
16 19

Larva migrans caused by the common raccoon ascarid, Baylisascaris procyonis, is a zoonotic disease of critical importance in North America. Recently we encountered the first proven outbreak of this disease in Japan in domestic rabbits (Oryctolagus cuniculus) in a small wildlife park. In this park, raccoons (Procyon lotor) had been kept for 9 years, and one raccoon was donated to the park by a pet owner 8 weeks prior to the occurrence of an outbreak in rabbits. Of 12 total raccoons, three raccoons including the donated one shed B. procyonis eggs in the feces, and two of these positive raccoons were kept in metal mesh cages on wooden pedestals, 2 m distant from the rabbit enclosure. Circumstantial evidence indicates that the donated raccoon is the likely source of this outbreak. Treatment of the raccoons with an ascaricide and decontamination by extensive flaming of the cages and the contaminated dirt floor of the park achieved a transient disappearance of ascarids from all 12 enclosed raccoons. Three months after the control measures began, recurrent ascarid infection was detected in three young raccoons of less than 1.5 years of age. The potential risk of serious zoonosis by B. procyonis as well as the difficulty in a clearance of contaminated areas should be considered by pet owners and public health workers in Japan.
著者
Hitoshi NAKANO Yuki KAMEO Hiroshi SATO Masami MOCHIZUKI Mayumi YOKOYAMA Shigehiko UNI Takahiro SHIBASAKI Ken MAEDA
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.71, no.12, pp.1661-1663, 2009 (Released:2009-12-31)
参考文献数
16
被引用文献数
11 12

Canine distemper virus (CDV) causes a lethal disease among members of the Carnivora. To clarify the distribution of CDV in wild animals, we examined 106 raccoon sera collected from two prefectures in Japan, Hyogo and Osaka, from 2005 to 2007. Among them, 34 raccoons (32.1%) possessed a virus-neutralizing (VN) antibody to KDK-1 strain (genotype Asia-1). There was no significant difference in seroprevalence of CDV regardless of places, gender, and body weights. In Hyogo, a geometric mean of VN titers to KDK-1 was significantly higher than that to Onderstepoort (vaccine strain), indicating that KDK-1-like CDV different from vaccine strain might have spread among raccoon population in Hyogo. In conclusion, CDV is epidemic among feral raccoons in Japan, suggesting that CDV might have been spreading among Japanese wild animals.
著者
佐藤 洋 Hiroshi Sato
出版者
昭和女子大学近代文化研究所
雑誌
学苑 (ISSN:13480103)
巻号頁・発行日
no.810, pp.118-126, 2008-04

This research is going to deal with the characteristics of Chinese immigrants. It will make use of the movie titled THE JOY LUCK CLUB. This unusually named club is a group of four mothers who enjoy playing mahjong regularly. They have been playing the game for as many as thirty years, since they migrated to San Francisco from China. They eat food or snacks they cook for themselves and chat and gossip while playing. The stories of how they had to emigrate from their home country is told through their chatting. The movie shows that each of the mothers has her own sad background. Another important topic they always discuss is their family stories, especially those of their special daughters. The movie describes one story after another of how each mother experienced hardship in her younger days in China, and how she is now struggling with new problems related to the generation gap. Their history and struggles are the history and struggles characteristic of Chinese immigration to America. Since other ways of immigrating to America (such as from England, Ireland, or Poland) were analyzed in Gakuen No. 798, issued last April, comparison with that analysis and the difference from immigration types of other ethnic groups will be researched. This will reveal the different characteristics as well as similarities of Chinese immigration from that of immigrants from other countries.
著者
Makoto Matsubara Hiroshi Sato Kenji Uehira Masashi Mochizuki Toshihiko Kanazawa
出版者
Fuji Technology Press Ltd.
雑誌
Journal of Disaster Research (ISSN:18812473)
巻号頁・発行日
vol.12, no.5, pp.844-857, 2017-10-01 (Released:2018-11-01)
参考文献数
34
被引用文献数
20

Tomographic analysis of the seismic velocity structure beneath oceans has always been difficult because offshore events determined by onshore seismic networks have large uncertainties in depth. In order to use reliable event locations for our computations, we have developed a method to use the hypocentral depths determined by the NIED F-net with moment tensor solutions using long-period (20-50 s) waves from offshore events away from onshore seismic networks. We applied seismic tomographic method to events occurring between the years 2000 and 2015 to generate a tomographic image of the Japanese Islands and the surrounding using travel time data picked by the NIED Hi-net, hypocenteral information for onshore earthquakes from the Hi-net, and hypocenter information for offshore events from the F-net. The seismic velocity structure at depths of 30-50 km beneath the Pacific Ocean off the east coast of northeastern Japan and onshore Japan was clearly imaged using both onshore and offshore event date. The boundary between high and low P-wave velocities (Vp) is clearly seen at the Median Tectonic Line beneath southwestern Japan at depths of 10 and 20 km. We discuss how the high-Vp lower crust and low-Vp upper crust beneath central Japan and towards the Sea of Japan are responsible for the failed rift structures formed during the opening of the Sea of Japan. Due to consequent shortening, the crustal deformation has been concentrated along the failed rift zone. Resolution of shallow structures beneath the ocean is investigated using S-net data, confirming the possibility of imaging depths of 5-20 km. In future studies, application of S-net data will be useful in evaluating whether the failed rift structure, formed during the late Cretaceous to early Tertiary, continues towards the shallow regions beneath the Pacific Ocean.
著者
Satoshi Kumakura Takashi Nakamichi Nonoka Suzuki Shu Yamakage Ayako Ishikawa Emi Fujikura Satoko Sato Takeshi Aoki Hiroaki Musha Katsuko Kikuchi Tasuku Nagasawa Hiroshi Sato Sadayoshi Ito Mariko Miyazaki
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.2378-18, (Released:2019-02-01)
参考文献数
22
被引用文献数
4

A 66-year-old man was admitted to our hospital because of multiple refractory skin ulcers. Based on his severe systemic arterial calcification and severe calcium-phosphate imbalance due to severe kidney dysfunction, we initially considered calciphylaxis. However, a skin biopsy provided a diagnosis of cholesterol crystal embolization. Although we initiated hemodialysis, steroid treatment, and low-density lipoprotein-cholesterol apheresis, he died of multiple intestinal perforation. An autopsy showed cholesterol crystals occluding multiple organ arterioles. This case suggests that skin ulcers in patients with chronic kidney disease may be an important diagnostic hallmark and may be associated with several serious diseases.
著者
Shiro Oguma Itiro Ando Takuo Hirose Kazuhito Totsune Hiroshi Sekino Hiroshi Sato Yutaka Imai Masako Fujiwara
出版者
東北ジャーナル刊行会
雑誌
The Tohoku Journal of Experimental Medicine (ISSN:00408727)
巻号頁・発行日
vol.227, no.3, pp.217-223, 2012 (Released:2012-07-07)
参考文献数
27
被引用文献数
5 22

Patients with renal failure undergoing hemodialysis often have muscle cramps during and after the dialysis therapy. Muscle cramps are defined as the sudden onset of a prolonged involuntary muscle contraction accompanied with severe pain, resulting in early termination of a HD session and inadequate dialysis. The etiology of the cramps is unknown and effective anti-cramp medicine is not available. We have hypothesized that water-soluble vitamins are deficient in HD patients. Accordingly, we administrated biotin to 14 patients who had frequent muscle cramps during HD sessions. Oral administration of 1 mg/day biotin promptly reduced the onset and the severity of cramps in 12 patients both during and after HD. Then, the plasma biotin levels were measured by an enzyme-linked immunosorbent assay method (ELISA) in HD patients, including 14 patients with cramps and 13 patients without cramps, and 11 healthy volunteers. Plasma biotin levels were elevated in 27 HD patients at baseline compared with healthy volunteers [451 (377 - 649) vs. 224 (148 - 308) ng/l, median (lower-upper quartiles); p < 0.0001]. Unexpectedly, among the 14 cramp patients, the biotin levels were significantly higher in biotin-ineffective 7 patients than biotin-effective 7 patients [1,064 (710 - 1,187) vs. 445 (359 - 476) ng/l; p < 0.001]. Thus, the biotins measured by ELISA may consist of not only intact biotin but also its metabolites that do not function as a vitamin. In conclusion, biotin administration is one choice to relieve HD patients from muscle cramps regardless of their elevated plasma biotin levels.
著者
Thinh Cong NGUYEN Ying-Chun LI Patrice MAKOULOUTOU Lea Angsinco JIMENEZ Hiroshi SATO
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.12-0025, (Released:2012-06-01)
被引用文献数
3 13 2

The northern snakehead Channa argus, native to China, Russia and Korea, is currently found widespread throughout Japan following its original introduction during the 1920s. A parasitological study of 10 snakeheads fished from the Fushinogawa River running through Yamaguchi City, Japan, detected 2–101 (average, 23.7) metacercariae per 100 g of trunk muscle from each fish. The trematode was identified as metacercariae of Posthodiplostomum sp. (Strigeidida: Diplostomidae) morphologically and characterized genetically based on the ribosomal RNA gene (rDNA). Phylogenetic trees were constructed on the basis of either the 18S, ITS or 28S region of rDNA to assess the relationship among members of the family Diplostomidae. The addition of genetic data from more diplostomid taxa, particularly Posthodiplostomum cuticola recorded from a variety of freshwater fish in Eurasia, would facilitate the precise identification of the present species.