著者
井口 理 Olsen B. S. Vaesel M. T. Johannsen H. V. Søjbjerg J. O.
出版者
Japan Shoulder Society
雑誌
肩関節 (ISSN:09104461)
巻号頁・発行日
vol.20, no.1, pp.87-90, 1996

The intraarticular pressures of the glenohumeral joint were measured in 15 cadaveric shoulders during passive movement of the humerus and under various inferior loads on the humerus. Using the fiber-optic transducertipped catheter and air-tight connector, the basic intraarticular pressure was measured directly without the injection of any physiological saline solution the joint prior to the measurement. The initial intraarticular pressures were all negative with a mean value of -67.8 mmHg. During abduction-adduction movement the minimal intraarticular pressure was measured at 20 degrees of humeral abduction. During rotation, the minimal intraarticular pressure was observed at neutral humeral rotation. The intraarticular pressure decreased nearly linearly with the increasing inferior load on the humerus. These results indicate that the intraarticular pressure takes part in the stabilization of the glenohumeral joint and the negative intraarticular pressure of the glenohumeral joint induces the maximal stabilizing effect at 20 degrees of humeral abduction and neutral humeral rotation.
著者
J.S.ミル著 村井久二訳
出版者
木鐸社
巻号頁・発行日
1978
著者
Pamela S. Combs Teruhiko Imamura Umar Siddiqi Saeid Mirzai Robert Spiller Corinne Stonebraker Colleen LaBuhn Heather Bullard Pamela Simone Valluvan Jeevanandam
出版者
International Heart Journal Association
雑誌
International Heart Journal (ISSN:13492365)
巻号頁・発行日
pp.19-660, (Released:2020-04-29)
参考文献数
20
被引用文献数
3

The use of opioids during left ventricular assist device (LVAD) support is increasing, but the implication remains unknown. We investigated the association between the use of opioid and morbidities during LVAD supports. We retrospectively reviewed the clinical data of patients who received LVAD between 2014 and 2017, which were stratified by the use of opioid at post-LVAD 3 months. Among 136 patients, 77 (57%) were in the opioid group. Hemoglobin and albumin were lower, and C-reactive protein was higher at baseline and 3 months later in the opioid group (P < 0.05 for all). The opioid group displayed worse hemodynamics, with higher pulmonary capillary wedge pressure and central venous pressure (P < 0.05 for both). Furthermore, the opioid group had higher incidences of gastrointestinal bleeding (31% versus 17%, P = 0.043) and sepsis (30% versus 13%, P = 0.036) during the 1 year observational period, whereas survivals were not stratified by the use of opioid (83% versus 90%, P = 0.27). Opioid use was associated with morbidities accompanied by poor hemodynamics during LVAD supports. The detailed causality of opioid use on morbidities remains a future concern.
著者
Sachiko Baba Ehab S. Eshak Kokoro Shirai Takeo Fujiwara Yui Yamaoka Hiroyasu Iso
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
pp.JE20190160, (Released:2019-11-02)
参考文献数
37
被引用文献数
8

Background: Spanking can cause adverse psychological development and biological functional changes in children. However, spanking is widely used by parents in Japan. This study explored the risk factors for family member’s spanking of 3.5-year-old children using nationwide population data in Japan.Methods: Surveys were administered to family members in Japan who had a child in 2001 (first cohort) or in 2010 (second cohort), and the data when their child was 0.5, 1.5, and 3.5 years old were used. We used multivariate binary and ordinal logistic regression analyses to examine the associations between risk factors and spanking children at 3.5 years of age, which was subcategorized into frequencies of never, sometimes, and always spanking, presented with odds ratios (ORs) and 95% confidence intervals (CIs).Results: Among 70,450 families, 62.8% and 7.9% sometimes and always spanked their children, respectively. Children in the second cohort were spanked less frequently compared with those in the first cohort, and fathers who responded to the questionnaire spanked children less frequently than mothers who responded. Identified associated factors for spanking were male child, presence of siblings of the child, not living in a two-parent household, not living in a three-generation household, younger parents, parents with lower education, no outside work or unstable work, and lower family income.Conclusions: We found a high prevalence of spanking and its associated factors. Approaching those with lower socioeconomic factors and promoting fathers’ involvement in parenting may be important public health strategies for reducing and preventing spanking.
著者
Bruce S. XIN 佐藤 直正 丹那 晃央 大石 泰生 小西 洋平 清水 史彦
出版者
公益社団法人 高分子学会
雑誌
高分子論文集 (ISSN:03862186)
巻号頁・発行日
vol.75, no.6, pp.515-526, 2018-11-25 (Released:2018-11-22)
参考文献数
29

筆者らは,エチレンと極性モノマーの共重合について研究を行ってきた.G. C. Bazanらとの共同研究から,α-iminocarboxamideをリガンドとする中性のNi錯体が,共触媒を必要としないsingle-site触媒として,エチレンとアクリル酸エステルの共重合を進行させることを見いだした.ただし,この触媒系は耐熱性が低く,40°C程度の低温重合が必要であったことから,さらに別の触媒系について探索を行った.その結果,ホスフィノフェノールをリガンドとする中性Ni錯体が,エチレンとアクリル酸エステルの共重合をより高温で触媒し,高度に直鎖状の共重合体を生成することを見いだした.そして,このリガンドにメトキシ基による効果を組み込むことにより,共重合活性,分子量,アクリル酸エステル含量の点で,性能を大きく向上させることに成功した.

1 0 0 0 OA 男子手淫論

著者
T S
出版者
順天堂医学会
雑誌
順天堂医学 (ISSN:00226769)
巻号頁・発行日
vol.T3, no.494, pp.139-148, 1914-02-25 (Released:2015-06-13)
著者
Kenji Tsuchiya Tomoko Yoshiki Ryota Nakajima Hideo Miyaguchi Victor S. Kuwahara Satoru Taguchi Tomohiko Kikuchi Tatsuki Toda
出版者
The Plankton Society of Japan, The Japanese Association of Benthology
雑誌
Plankton and Benthos Research (ISSN:18808247)
巻号頁・発行日
vol.8, no.2, pp.74-87, 2013-05-25 (Released:2014-08-30)
参考文献数
74
被引用文献数
17 30

Climate change has the potential for intensification of typhoons, which will cause stronger effects on aquatic ecosystems in the future. The effect of typhoon Mawar (T0511), passing Manazuru Port located in the western part of Sagami Bay, Japan, was investigated from August to September 2005. Immediately after the passage of Mawar, photosynthetically available radiation showed high values, salinity decreased dramatically and nutrient concentrations (NO2+NO3, PO4 and Si(OH)4) increased. Skeletonema spp. and Leptocylindrus spp. were dominant after the passage of Mawar, and their succession was linked to the variability of the N/P ratio. Primary production was highest at 349 mg C m−3 day−1 three days after Mawar, and high assimilation numbers lasted for nine days. The integrated primary production during the nine days after Mawar was 2.1×103 mg C m−3, which accounted for 7.2–9.1% of the annual primary production in the upper waters of Sagami Bay. The study confirms that enhanced primary production induced by episodic typhoon events in temperate coastal regions are significant, and should be considered in annual primary production estimates.
著者
Kenta Masui Mio Harachi Webster K. Cavenee Paul S. Mischel Noriyuki Shibata
出版者
JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY
雑誌
ACTA HISTOCHEMICA ET CYTOCHEMICA (ISSN:00445991)
巻号頁・発行日
vol.53, no.1, pp.1-10, 2020-02-28 (Released:2020-02-28)
参考文献数
85
被引用文献数
21

Cancer is widely considered to be a set of genetic diseases that are currently classified by tissue and cell type of origin and, increasingly, by its molecular characteristics. This latter aspect is based primarily upon oncogene gains, tumor suppressor losses, and associated transcriptional profiles. However, cancers are also characterized by profound alterations in cellular metabolism and epigenetic landscape. It is particularly noteworthy that cancer-causing genomic defects not only activate cell cycle progression, but regulate the opportunistic uptake and utilization of nutrients, effectively enabling tumors to maximize growth and drug resistance in changing tissue and systemic microenvironments. Shifts in chromatin architecture are central to this dynamic behavior. Further, changes in nutrient uptake and utilization directly affect chromatin structure. In this review, we describe a set of recent discoveries of metabolic and epigenetic reprogramming in cancer, and especially focus on the genomically well-characterized brain tumor, glioblastoma. Further, we discuss a new mode of metabolic regulation driven by epigenetic mechanisms, that enables cancer cells to autonomously activate iron metabolism for their survival. Together, these underscore the integration of genetic mutations with metabolic reprogramming and epigenetic shifts in cancer, suggesting a new means to identifying patient subsets suitable for specific precision therapeutics.