著者

Shang-Chi Wu Lian-Yu Chen Po-Chang Hsiao Te-Tien Ting Cheng-Fang Yen Shu-Sen Chang Chung-Yi Li Hao-Jan Yang Chia-Feng Yen Chuan-Yu Chen Jiun-Hau Huang Yu-Kang Tu Wei J. Chen

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20220356, (Released:2023-07-15)

参考文献数

41

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Background: Administering premixed drugs in commodity packets was first reported in Asia in 2015, but there continues to be a dearth of related population-based data. This study aimed at examining (1) the prevalence of drug packet use in the population and (2) the sociodemographic profiles, particularly gender distribution, of drug packet users.Methods: Data were derived from a survey of 18,626 Taiwanese civilians, aged 12-64 years, using stratified, multi-stage, random sampling in 2018. Participants anonymously completed a computer-assisted self-interview on tablet computers which covered the use and problematic use of illicit drugs/inhalants, prescription drugs and other psychoactive substances, among others.Results: Approximately 1.46% of respondents had a lifetime use of illicit drugs, with drugs in commodity packets (0.18%) being ranked the fifth-most commonly used illicit drugs, higher than nitrous oxide (0.14%) and heroin (0.09%). Ten formats of drug packets were endorsed by users. Approximately 81.6% of persons with drug packet use had a lifetime use of other illicit drugs. The correlates of the use of drugs in commodity packets were similar to those of the exclusive use of other drugs except that there was a lack of gender differences in the use of drugs in commodity packets but not in the exclusive use of other drugs.Conclusion: Drugs in commodity packets have become a common way of administering illicit drugs in the population in Taiwan, and there were no gender differences among users. Our findings have implications for more efficient drug testing and culturally appropriate intervention for drug packet use.

著者

Ji-Hyun JANG Myoung Geun LEE Sang Uk WOO Chung Ok LEE Jin-Kyu YI Duck-Su KIM

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.35, no.4, pp.606-612, 2016-07-29 (Released:2016-07-30)

参考文献数

33

被引用文献数

33 34

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This study compared the dentin bond strength of a new universal adhesive with that of contemporary multi-step dentin adhesives. Six experimental groups were prepared according to the adhesives used and their application modes: Optibond FL (OB), Adper Single Bond Plus (SB), One-Step Plus (OS), Clearfil SE Bond (CS), All-Bond Universal using etch-and-rinse mode (ABE), and AllBond Universal using self-etch mode (ABS). Micro-tensile bond strength (µTBS) and failure mode were evaluated for each group. The bonded interface was analyzed using transmission electron microscopy (TEM). As a result, µTBS of 6 experimental groups was followed as: OB=ABE=SE=ABS>SB>OS group. TEM micrographs of ABE and ABS groups revealed a homogenous adhesive layer formation. In conclusion, a new universal adhesive can make reliable bond to dentin, regardless of the application mode.

著者

Donald D. Heistad Yoshinobu Wakisaka Jordan Miller Yi Chu Ricardo Pena-Silva

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.73, no.2, pp.201-207, 2009 (Released:2009-01-23)

参考文献数

44

被引用文献数

101 107

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Oxygen radicals, and other reactive oxygen species, may play an important role in the pathophysiology of atherosclerosis, stroke, and other cardiovascular diseases. Mechanisms that account for oxidative stress in different cardiovascular diseases are diverse; for example, increases in activity of NAD(P)H oxidase, "uncoupling" of nitric oxide synthase, and maladaptive changes in expression of antioxidants can all contribute to increases in oxidative stress. Very different patterns of pro-and antioxidant mechanisms that contribute to increases in oxygen radicals in atherosclerotic plaques, hemorrhagic strokes, and aortic valve stenosis have been observed. A disappointment, in relation to the hypothesis that oxygen radicals contribute to cardiovascular risk, is that many studies indicate that antioxidant vitamins fail to reduce the risk of cardiovascular disease. Better understanding of mechanisms that lead to increases in oxidative stress in different cardiovascular diseases may lead to more effective antioxidant prevention or treatment of diseases. (Circ J 2009; 73: 201 - 207)

著者

Yi Yen Kuo-Chun Hung Yi-Hsin Chan Victor Chien-Chia Wu Yu-Ting Cheng Chia-Pin Lin Jih-Kai Yeh Pao-Hsien Chu Shao-Wei Chen

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-22-0718, (Released:2023-04-06)

参考文献数

38

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Background: Studies of the influence of smaller body type on the severity of prosthesis-patient mismatch (PPM) after small-sized surgical aortic valve replacement (SAVR) are few, but the issue is particularly relevant for Asian patients.Methods and Results: 695 patients who underwent SAVR with bioprosthetic valves had their hemodynamic valve performance analyzed at 3 months, 1 year, 3 years, and 5 years after operation, and clinical outcomes were assessed. The patients were stratified into 3 valve size groups: 19/21, 23, and 25/27 mm. A smaller valve was associated with higher mean pressure gradients at the 4 time points after operation (P trend <0.05). However, the 3 valve size groups demonstrated no significant differences in the risk of clinical events. At none of the time points did patients with projected PPM show increased mean pressure gradients (P>0.05), whereas patients with measured PPM did (P<0.05). Compared with patients with projected PPM, those with measured PPM demonstrated higher rates of infective endocarditis readmission (adjusted hazard ratio [aHR] 3.31, 95% confidence interval [CI] 1.06–10.39) and a higher risk of composite outcomes (aHR 1.45, 95% CI 0.95–2.22, P=0.087).Conclusions: Relative to those receiving larger valves, patients receiving small bioprosthetic valves had poorer hemodynamic performance but did not demonstrate differences in clinical events in long-term follow-up.

著者

Tzu-Yi Lu Chih-Da Wu Yen-Tsung Huang Yu-Cheng Chen Chien-Jen Chen Hwai-I Yang Wen-Chi Pan

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20220262, (Released:2023-03-11)

参考文献数

52

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Background: Ambient particulate matter is classified as a human Class 1 carcinogen, and recent studies found a positive relationship between fine particulate matter (PM2.5) and liver cancer. Nevertheless, little is known which specific metal constituent contributes to the development of liver cancer.Objective: To evaluate the association of long-term exposure to metal constituents in PM2.5 with the risk of liver cancer using a Taiwanese cohort study.Methods: A total of 13,511 Taiwanese participants were recruited from the REVEAL-HBV in 1991-1992. Participants’ long-term exposure to eight metal constituents (Ba, Cu, Mn, Sb, Zn, Pb, Ni, and Cd) in PM2.5 was based on ambient measurement in 2002-2006 followed by a land-use regression model for spatial interpolation. We ascertained newly developed liver cancer (i.e. hepatocellular carcinoma [HCC]) through data linkage with the Taiwan Cancer Registry and national health death certification in 1991-2014. A Cox proportional hazards model was utilized to assess the association between exposure to PM2.5 metal component and HCC.Results: We identified 322 newly developed HCC with a median follow-up of 23.1 years. Long-term exposure to PM2.5 Cu was positively associated with a risk of liver cancer. The adjusted hazard ratio (HR) was 1.13 (95% confidence interval [CI]: 1.02, 1.25; p-value=0.023) with one unit increment on Cu normalized by PM2.5 mass concentration in the logarithmic scale. The PM2.5 Cu-HCC association remained statistically significant with adjustment for co-exposures to other metal constituents in PM2.5.Conclusions: Our findings suggest PM2.5 containing Cu may attribute to the association of PM2.5 exposure with liver cancer.

著者

Hsin-Yi YANG Wan-Hsuan WANG Jun-Ye ZHAN Ya-Ling HUANG Wei-Yi CHENG

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.66, no.Supplement, pp.S356-S360, 2020 (Released:2021-02-22)

参考文献数

25

被引用文献数

3

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Overweight and obesity are associated with many chronic diseases. This study aimed to clarify the possible effects of consuming golden kiwifruit as daily fruit intake on body composition, lipid metabolism and inflammatory responses. Methods: We recruited twenty-two overweight and obese subjects and they were asked to consume two golden kiwifruit every day during the 6-wk experimental period. At the baseline and end of the study, fasting blood samples were collected and anthropometric and blood pressure measurement were conducted. Results: During the experimental period, no adverse effect and dropout were reported. At the end of the study, a significant decrease in body fat and circulatory tumor necrosis factor (TNF)-α concentration were found. In addition, there was a reduction of angiotensin II (AgII) concentration and systolic blood pressure in subjects with baseline systolic blood pressure (SBP) ≥125 mmHg. Conclusion: Our results suggested that daily golden kiwifruit intake can reduce body fat mass, improve blood pressure and regulating inflammatory responses in overweight and obese young adults.

著者

Chung-Yi Li Chia-Lun Kuo Ya-Hui Chang Chin-Li Lu Santi Martini Wen-Hsuan Hou

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.32, no.9, pp.423-430, 2022-09-05 (Released:2022-09-05)

参考文献数

54

被引用文献数

2 5

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Background: We aimed to investigate associations between exposure to various trajectories of severe hypoglycemic events and risk of dementia in patients with type 2 diabetes.Methods: In 2002–2003, 677,618 patients in Taiwan were newly diagnosed as having type 2 diabetes. Among them, 35,720 (5.3%) experienced severe hypoglycemic events during the 3-year baseline period following diagnosis. All patients were followed from the first day after baseline period to the date of dementia diagnosis, death, or the end of 2011. A group-based trajectory model was used to classify individuals with severe hypoglycemic events during the baseline period. Cox proportional hazard models with the competing risk method were used to relate dementia risk to various severe hypoglycemia trajectories.Results: After a median follow-up 6.70 and 6.10 years for patients with and without severe hypoglycemia at baseline, respectively, 1,952 (5.5%) individuals with severe hypoglycemia and 23,492 (3.7%) without developed dementia during follow-up, for incidence rates of 109.80 and 61.88 per 10,000 person-years, respectively. Four groups of severe hypoglycemia trajectory were identified with a proportion of 18.06%, 33.19%, 43.25%, and 5.50%, respectively, for Groups 1 to 4. Groups 3 (early manifestation but with later decrease) and 4 (early and sustained manifestation) were associated with a significantly increased risk of dementia diagnosis, with a covariate-adjusted subdistribution hazard ratio of 1.22 (95% confidence interval, 1.14–1.31) and 1.25 (95% confidence interval, 1.02–1.54), respectively.Conclusion: Our analysis highlighted that early manifestation of severe hypoglycemic events may contribute more than does late manifestation to the risk of dementia among individuals newly diagnosed as having type 2 diabetes.

著者

Chao Wang Heng Jiang Yi Zhu Yingying Guo Yong Gan Qingfeng Tian Yiling Lou Shiyi Cao Zuxun Lu

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.32, no.9, pp.415-422, 2022-09-05 (Released:2022-09-05)

参考文献数

52

被引用文献数

1 2

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Background: Increasing number of studies have suggested the time to first cigarette after waking (TTFC) have significant positive effect on respiratory diseases. However, few of them focused on the Chinese population. This study aims to estimate the impact of TTFC on the prevalence of chronic respiratory diseases (CRD) in Chinese elderly and explore the association in different sub-populations.Methods: Cross-sectional data of demographic characteristics, living environment, smoking-related variables, and CRD were drawn from the Chinese Longitudinal Healthy Longevity Survey in 2018. Multivariate stepwise logistic regression analyses were conducted to examine the association of the TTFC with the prevalence of CRD.Results: This study includes 13,208 subjects aged 52 years and older, with a mean age of 85.3 years. Of them, 3,779 participants were ex- or current smokers (44.9% had the TTFC ≤30 minutes, 55.1% >30 minutes) and 1,492 had suffered from CRD. Compared with non-smokers, participants with TTFC ≤30 minutes seemed to have higher prevalence of CRD (OR 1.97; 95% CI, 1.65–2.35) than those with TTFC >30 minutes (OR 1.70; 95% CI, 1.44–2.00), although the difference was statistically insignificant (Pinteraction = 0.12). Compared with TTFC >30 minutes, TTFC ≤30 minutes could drive a higher prevalence of CRD among female participants, those aged 90 years and older, urban residents, and ex-smokers (Pinteraction < 0.05).Conclusion: Shorter TTFC relates to higher prevalences of CRD in Chinese older females, those aged 90 years and older, urban residents, and ex-smokers. Delaying TTFC might partially reduce its detrimental impact on respiratory disease in these specific subpopulations.

著者

Yifang BAO Shigeru YAMASHITA Bing LI Tsung-Yi HO

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Fundamentals of Electronics, Communications and Computer Sciences (ISSN:09168508)

巻号頁・発行日

vol.E105-A, no.10, pp.1385-1391, 2022-10-01

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When we use a Programmable Microfluidic Device (PMD), we need to wash some contaminated area to use the chip for further experiments. Recently, a novel washing technique called Block-Flushing has been proposed. Block-Flushing washes contaminated area in PMDs by using buffer flows. In Block-Flushing, we need to keep a buffer flow from an input port to an output port of a PMD for a long period to dissolve residual contaminants. Thus, we may need a lot of buffer fluids and washing time even if the contaminated area is small. Another disadvantage of the washing method by Block-Flushing is such that we may not able to clean residual contaminants at valves completely by only buffer flows. To address the above-mentioned issues, this paper proposes a totally new idea to wash PMDs; our method does not use buffer flows, but washes contaminated area by using mixers. By using a mixer, we can dissolve residual contaminants at valves in the area of the mixer very efficiently. In this paper, we propose two methods to wash PMDs by using mixers. The first method can wash the whole chip area by using only four times of a single 2x2-mixer time. We also propose the second method which is a heuristic to reduce the number of moving valves because valves may wear down if they are used many times. We also show some experimental results to confirm that the second method can indeed decrease the number of used valves.

著者

Yali Feng Ying Yin Xuemei Zhao Yue Zhang Yi Zhou Zonghui Wu

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.34, no.10, pp.657-667, 2022 (Released:2022-10-01)

参考文献数

42

被引用文献数

3

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[Purpose] To assess the current state-of-the-art and the prevailing trends regarding the global use of blood flow restriction (BFR) in the past 20 years. [Participants and Methods] We retrieved literature relating to BFR from 1999 to 2020 using Web of Science. We conducted a bibliometric analysis of countries/institutions, cited journals, authors/cited authors, cited references, and keywords using CiteSpace. An analysis of counts and centrality was used to examine publication output, countries/institutions, core journals, active authors, foundation references, hot topics, and frontiers. [Results] Seven hundred seventy five references were included and the total number of publications has been continually increasing over the investigated period. Representatives of important academic groups are the Japanese scholars from the University of Tokyo as represented by Takashi Abe. Jeremy Paul Loenneke’s article (centrality: 0.15) was the most representative and symbolic reference with the highest centrality. The three topics identified were intervention (intensity resistance exercise, IRE), physiology (ischemia and muscular function) and behavior (adaptation and increase). The four frontier topics were phosphorylation, reduction, low intensity and arterial occlusion. [Conclusion] This study provides an insight into BFR and offers valuable information for BFR researchers to identify new perspectives for potential cooperation with collaborators and their related cooperative institutions.

著者

Yi Sun Jialai Zhu Norio Mori

出版者

Japan Brain Science society

雑誌

脳科学誌 (ISSN:13415301)

巻号頁・発行日

vol.43, pp.50-57, 2014-05-30 (Released:2017-06-01)

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In recent years, small animal PET-CT, as a biomedical research technology, is widely used on the animal model research. High-resolution animal PET scanner has been developed that can provide accurate rates of cerebral glucose metabolism in conscious rats. This paper mainly discusses brain metabolic changes induced by radiation injury in according to glucose metabolism study in brain and the development of small animal PET

著者

Shen Chen Yi Sun

出版者

Japan Brain Science society

雑誌

脳科学誌 (ISSN:13415301)

巻号頁・発行日

vol.41, pp.48-54, 2013-09-30 (Released:2017-06-01)

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In recent years, hematopoietic stem cells to repair damage well, especially in the CD34 positive cells as the representative of the hematopoietic cell become a research hotspot, but the CD34 positive cells in the body content low, how to get a large number of CD34 positive cells become one of the difficulties of CD34 positive cells. This article reviews the methods commonly used to collect CD34 isthmic cells now, convenient for researchers to find a suitable or find new research methods.

著者

Quanyi LIU Qian ZHU Wentian ZHU Xiaoying YI

出版者

The Electrochemical Society of Japan

雑誌

Electrochemistry (ISSN:13443542)

巻号頁・発行日

vol.90, no.8, pp.087003, 2022-08-05 (Released:2022-08-05)

参考文献数

31

被引用文献数

1 5

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With the improvement of lithium-ion batteries in civil aviation transportation, the thermal safety of lithium-ion batteries can not be ignored. Especially in a battery pack, the thermal runaway of batteries can spread from cell to cell, resulting in catastrophic hazards. This work focuses on the experimental setup and analysis of the experimental parameters of lithium-ion batteries with different thicknesses of aerogel felt to study the blocking effect of barrier materials on thermal runaway propagation of lithium-ion batteries in civil aviation transport. The aerogel felt was selected as the barrier material and a series of experiments were carried out with different thicknesses of 1 mm, 3 mm, and 6 mm. The results demonstrated that the increase of aerogel felt thickness exhibited excellent performance in delaying lithium-ion battery thermal runaway. Additionally, a simplified thermal model of thermal runaway propagation was proposed to explain the thermal runaway propagation in the battery to adjacent batteries. These results provide valuable suggestions and enlightenment for the aviation safety transportation of lithium-ion batteries.

著者

Quanyi LIU Qian ZHU Wentian ZHU Xiaoying YI Xu HAN

出版者

The Electrochemical Society of Japan

雑誌

Electrochemistry (ISSN:13443542)

巻号頁・発行日

vol.90, no.8, pp.087004, 2022-08-05 (Released:2022-08-05)

参考文献数

21

被引用文献数

1 5

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To better understand the thermal runaway characteristics of lithium-ion batteries in civil aviation transportation environments, an experimental platform for the fire and explosion of lithium-ion batteries was designed and built. The 18650 NCM lithium-ion battery was selected as the test sample to study the influence of different initial pressures on the thermal runaway characteristics of the lithium-ion battery pack in a confined space. The results showed that, under 61 kPa, the initial thermal runaway triggering time is longer, the initial thermal runaway temperature is higher, and the explosion pressure and TNT equivalent are lower than that under 96 kPa. The mass loss increased with the increase of pressure and the number of batteries. In addition, the initial thermal runaway triggering time and temperature are affected by the number of batteries. These results could provide some support for civil aviation transportation safety.

著者

Geng-Ruei Chang Yi-Shin Chiu Ying-Ying Wu Wen-Ying Chen Jiunn-Wang Liao Te-Hsin Chao Frank Chiahung Mao

出版者

The Japanese Pharmacological Society

雑誌

Journal of Pharmacological Sciences (ISSN:13478613)

巻号頁・発行日

vol.109, no.4, pp.496-503, 2009 (Released:2009-04-17)

参考文献数

51

被引用文献数

105 122

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Rapamycin (RAPA), an immunosuprpressive drug used extensively to prevent graft rejection in transplant patients, has been reported to inhibit adipogenesis in vitro. In this study, we investigated the anti-obesity effects of RAPA in C57BL/6J mice on a high-fat diet (HFD). Mice treated with RAPA (2 mg/kg per week for 16 weeks) had reduced body weight and epididymal fat pads/body weight, reduced daily food efficiency, and lower serum leptin and insulin levels compared with the HFD control mice. However, RAPA-treated mice were hyperphagic, demonstrating an increase in food intake. Dissection of RAPA-treated mice revealed a marked reduction in fatty liver scores, average fat cell size, and percentage of large adipocytes of retroperitoneal and epididymal white adipose tissue (RWAT and EWAT), compared to the HFD control mice. These results suggest that RAPA prevented the effect of the high-fat diet on the rate of accretion in body weight via reducing lipid accumulation, despite greater food intake. It is likely that RAPA may serve as a potential strategy for body weight control and/or anti-obesity therapy.

著者

Yongtae KO Naoto TSUJII Yuichi TAKASE Akira EJIRI Osamu WATANABE Hibiki YAMAZAKI Kotaro IWASAKI Peng YI James H.P. RICE Yuki OSAWA Takuma WAKATSUKI Maiko YOSHIDA Hajime URANO

出版者

The Japan Society of Plasma Science and Nuclear Fusion Research

雑誌

Plasma and Fusion Research (ISSN:18806821)

巻号頁・発行日

vol.16, pp.1402056, 2021-04-21 (Released:2021-05-12)

参考文献数

20

被引用文献数

5

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We investigated electron cyclotron (EC) wave assisted low voltage Ohmic start-up in the conventional field null configuration (FNC) and the trapped-particle configuration (TPC) in the TST-2 spherical tokamak device. The upper pressure limit for successful burn-through increased when EC power was applied for both the FNC and TPC. On the other hand, at low prefill pressure, breakdown was delayed in the FNC start-up. The achievable plasma current also decreased especially at high EC power. By applying the TPC, fast breakdown was recovered even at high EC power. The plasma current ramp-up rate was also greater with TPC compared with FNC at the same loop voltage waveform. The lower prefill pressure limit for successful breakdown expanded in the TPC compared to that in the FNC. The higher vertical field decay index resulted in faster EC breakdown. The reduction of the upper pressure limit due to impurities was the same in the FNC and TPC indicating that the poloidal field configuration did not significantly affect the upper pressure limit for successful burn-through.

著者

James H.P. RICE Naoto TSUJII Yuichi TAKASE Akira EJIRI Osamu WATANABE Hibiki YAMAZAKI Yi PENG Kotaro IWASAKI Yuki AOI Yongtae KO Kyohei MATSUZAKI Yuki OSAWA

出版者

The Japan Society of Plasma Science and Nuclear Fusion Research

雑誌

Plasma and Fusion Research (ISSN:18806821)

巻号頁・発行日

vol.15, pp.2402009, 2020-04-06 (Released:2020-05-08)

参考文献数

13

被引用文献数

4

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A new Langmuir probe has been designed and installed in TST-2 for measurements of Scrape-Off Layer plasmas (SOL). Non-inductive current drive is considered essential for spherical tokamak reactors. It has previously been shown that a large amount of injected Lower Hybrid Wave (LHW) power is lost in the SOL [1]. A full density profile of SOL conditions is necessary to accurately simulate the propagation of LHW in TST-2. A new probe was designed for durability, larger signal and Mach probe measurements. The new probe has been installed in TST-2 and results have been obtained. Temperature measurements show Te = 30 - 50 eV during RF injection and <10 eV otherwise. Density measurements show ne = 2.0 × 1015 m−3 and 1.5 × 1016 m−3 during flat-top RF power injection from Outboard- and Top-launch antennas, respectively. This is above the cut-off density for the 200 MHz LHW (5 × 1014 m−3) in TST-2, thus LHW can propagate through SOL plasma.

著者

Naoto TSUJII Yusuke YOSHIDA Yuichi TAKASE Akira EJIRI Osamu WATANABE Hibiki YAMAZAKI Yi PENG Kotaro IWASAKI Yuki AOI Yongtae KO Kyohei MATSUZAKI James H.P. RICE Yuki OSAWA

出版者

The Japan Society of Plasma Science and Nuclear Fusion Research

雑誌

Plasma and Fusion Research (ISSN:18806821)

巻号頁・発行日

vol.15, pp.2402010, 2020-04-06 (Released:2020-05-08)

参考文献数

13

被引用文献数

2 4

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Removal of the central solenoid is considered essential to realize a spherical tokamak fusion reactor, but non-inductive plasma start-up is a challenge. Start-up using lower-hybrid (LH) waves has been studied on the TST-2 spherical tokamak at the University of Tokyo. The equilibrium poloidal field is believed to be generated mostly by the wave driven fast electrons, which are highly non-thermal and have large orbit excursions from the flux surfaces due to low plasma current. Such an equilibrium can be qualitatively different from the Grad-Shafranov equilibrium routinely used for internal magnetic field reconstruction in a tokamak. In this work, the effect of fast electrons on the MHD equilibrium was investigated by considering the equilibrium solution of the hybrid-MHD model [Y. Todo and A. Bierwage, Plasma Fusion Res. 9, 3403068]. The fast electron distribution function was estimated using a LH current drive simulation based on ray-tracing and an orbit-averaged Fokker-Planck solver. The equilibrium solution of the hybrid-MHD model was successfully fitted to the magnetic and kinetic measurements. The resulting poloidal flux function was more skewed towards the outboard side when fast electrons were introduced, which was more consistent with the density profile measured by the Thomson scattering diagnostic.

著者

CHANG Yi MA Qianrong GUO Lijun DUAN Jing LI Jun ZHANG Xiaopeng GUO Xueliang LOU Xiaofeng CHEN Baojun

出版者

Meteorological Society of Japan

雑誌

気象集誌. 第2輯 (ISSN:00261165)

巻号頁・発行日

pp.2022-003, (Released:2021-09-30)

被引用文献数

7

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Meiyu front precipitation makes the region prone to frequent floods, mudslides, landslides, and other disasters, and has been the focus of ongoing and challenging meteorological research. Raindrop size distribution (RSD) is a fundamental method for exploring the characteristics and physical processes of rainfall. This study investigated the precipitation characteristics in Lushan mountainous areas during the Meiyu season using laser disdrometer observed RSD data from 2016 to 2019. For the average spectra of five rain rate classes, the concentrations of large raindrops (> 0.5 mm) increased with rain rate (R), while the concentrations of small raindrops (< 0.5 mm) increased only under rain rates higher than 10 mm h−1. The gamma distribution parameters of N0 and Λ increased/decreased with rain rate, and μ exhibited negative values in different rain rate classes. The distribution pattern features were N (D) = 721D−1.79e−1.20D. Distributions of the frequency for mass-weighted mean diameter (Dm) and the logarithm of the generalized intercept parameter (log10Nw) both showed a unique bimodal type, and an exceptionally high Nw (log10Nw > 4.5) subset with small Dm was determined. The stratiform and convective rain of RSD were also investigated. Dm − R and Nw − R showed similar variations in two types of precipitation. The lower μ values resulted in higher primary and constant coefficients in the quadratic polynomial fitting for the μ − Λ relationship (Λ = 0.0347μ2 + 1.180μ + 2.495). The Z − R relationship in stratiform precipitation characteristics was Z = 203R1.59. Further investigations showed that high Nw values usually occurred in persistent precipitation. The RSD can be characterized as high concentrations of the first two diameter classes with narrow spectrum width (< 1 mm), which were captured during in-cloud rain with a low but continuous rain rate (< 5 mm h−1). The mountainous topography plays an important role in reshaping the characteristics of RSD and the physical processes of precipitation.

著者

Wang Chao Jiang Heng Zhu Yi Guo Yingying Gan Yong Tian Qingfeng Lou Yiling Cao Shiyi Lu Zuxun

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

2021

被引用文献数

2

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<p><b>Background:</b> Increasing number of studies has suggested the time to first cigarette after waking (TTFC) have significant positive effect on respiratory diseases. However, few of them are focused on Chinese population. This study aims to estimate the impact of TTFC on the prevalence of chronic respiratory diseases (CRD) in Chinese elderly and explore the association in different sub-populations.</p><p><b>Methods:</b> Cross-sectional data of demographic characteristics, living environment, smoking-related variables, and CRD were drawn from the Chinese Longitudinal Healthy Longevity Survey in 2018. Multivariate stepwise logistic regression analyses were conducted to examine the association of the TTFC with the prevalence of CRD.</p><p><b>Results:</b> This study includes 13208 subjects aged 52 years and older, with a mean age of 85.3 years. Of them, 3779 participants are ex- or current smokers (44.9% had the TTFC ≤30 minutes, 55.1% >30 minutes) and 1503 have suffered from CRD. Compared with non-smokers, participants with TTFC ≤30 minutes seemed to have higher prevalence of CRD (OR 1.97; 95% CI, 1.65-2.35) than those with TTFC >30 minutes (OR 1.70; 95% CI, 1.44-2.00), although the difference was statistically insignificant (<i>P_interaction</i>=0.12). Compared with TTFC >30 minutes, TTFC ≤30 minutes could drive a higher prevalence of CRD among female participants, those aged 90 years and older, urban residents, and those ex-smokers (<i>P_interaction</i><0.05).</p><p><b>Conclusions:</b> Shorter TTFC relates to higher prevalences of CRD in Chinese older females, those aged 90 years and older, urban residents, and ex-smokers. Delaying TTFC might particially reduce its detrimental impact on respiratory disease in these specific subpopulations.</p>