著者

Yi Shuang Sun Wenke Heki Kosuke Qian An

出版者

American Geophysical Union

雑誌

Geophysical Research Letters (ISSN:00948276)

巻号頁・発行日

vol.42, no.10, pp.3998-4006, 2015-05-28

被引用文献数

77

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The global mean sea level (GMSL) was reported to have dropped 5 mm due to the 2010/2011 La Niña and have recovered in 1 year. With longer observations, it is shown that the GMSL went further up to a total amount of 11.6 mm by the end of 2012, excluding the 3.0 mm/yr background trend. A reconciled sea level budget, based on observations by Argo project, altimeter, and gravity satellites, reveals that the true GMSL rise has been masked by El Niño–Southern Oscillation-related fluctuations and its rate has increased since 2010. After extracting the influence of land water storage, it is shown that the GMSL has been rising at a rate of 4.4 ± 0.5 mm/yr for more than 3 years, due to an increase in the rate of both land ice loss and steric change.

著者

Ze Li Jing Zhang Yunjia Yang Huilan Xu Jianwu Wang Yi Yang

出版者

The Japan Society for Analytical Chemistry

雑誌

Analytical Sciences (ISSN:09106340)

巻号頁・発行日

pp.20N013, (Released:2020-08-21)

被引用文献数

5

著者

Chung-Yi LI Chao-Kang FENG

出版者

National Institute of Occupational Safety and Health

雑誌

Industrial Health (ISSN:00198366)

巻号頁・発行日

vol.37, no.4, pp.465-468, 1999 (Released:2007-03-29)

参考文献数

13

被引用文献数

10 9

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To assess the physiotherapist's exposure to radio frequency electromagnetic fields (RF) leaking from short wave diathermy equipment, we conducted on-site measurements of stray electric and magnetic fields (27.12MHz) close to continuous wave (CW) short wave equipment. The results show that the operator's knees may have the highest exposure level for both electric field (E-field) and magnetic field (H-field) in the normal operating position, i.e., behind the device console. The whole-body E-field exposure normally does not exceed the 1992 IEEE recommended limit during a normal treatment session. On the other hand, the operator's whole-body exposure to H-field was barely below the recommended limit. Our data suggest little chance of immediate harmful effects of RF leakage from the diathermy. Nonetheless, physiotherapists should still be advised to remain at a distance of at least 20cm from the electrodes and cables to avoid possible overexposure.

著者

En-Yi TING Grace

出版者

国際基督教大学ジェンダー研究センター

雑誌

Gender and Sexuality (ISSN:18804764)

巻号頁・発行日

no.15, pp.67-81, 2020-03-31

著者

Shuaibo Huang Ru Ding Yi Lin Zhiqing He Feng Wu Xianliang Dai Yihong Chen Yanping Gui Zhigang Huang Zonggui Wu Chun Liang

出版者

Japan Atherosclerosis Society

雑誌

Journal of Atherosclerosis and Thrombosis (ISSN:13403478)

巻号頁・発行日

vol.23, no.5, pp.632-643, 2016-05-02 (Released:2016-05-02)

参考文献数

59

被引用文献数

5 13

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Aim: Immunologic dysfunction was recently found to be one of the most important mechanisms underlying the initiation and development of atherosclerosis. Thymus involution can contribute to immune disturbance and disequilibrium of T-cell subsets. This study aimed to explore whether recent thymic emigration (RTE) is impaired in patients with coronary artery disease (CAD).Methods: Content of signal-joint T cell receptor excision circles (sj-TREC) in T lymphocytes, a molecular marker of RTE, was assessed among CAD patients and age-matched controls. Monochrome multiplex quantitative PCR method was used to assess the samples' telomere length in order to exclude the potential influence of T cell proliferation on the dilution of sj-TREC. Patients were grouped according to Gensini score (GS) (low, GS <18; intermediate, GS 18–41; high, GS >41). Ordinary logistic regression models were used to determine potential risk factors for CAD and GS tertiles.Results: Average copy numbers of sj-TREC per 106 T lymphocytes among patients with unstable angina, stable angina, and controls were 726±429, 1213±465, and 1795±838, respectively (P<0.001). However, there was no significant difference in telomere length among groups. Moreover, the content of sj-TREC in the high GS group was most significantly reduced than the low GS group (P<0.001). Multivariate logistic regression analysis revealed that lower sj-TREC was independently associated with the progression of CAD (OR=0.44, P<0.001) and higher GS (OR=0.4, P<0.001).Conclusion: Impaired RTE could be partly responsible for CAD development. Mechanisms may be involved in the disturbance of T lymphocyte compartment and interruption of maintained immune tolerance resulting from thymus involution.

著者

li na Yi 桃山学院大学文学研究科博士後期課程

雑誌

国際文化論集 = INTERCULTURAL STUDIES (ISSN:09170219)

巻号頁・発行日

no.31, pp.67-104, 2004-12-20

著者

王 一令 鷲尾 純一 Wang Yi-Ling Washio Junichi

出版者

筑波大学心身障害学系

雑誌

心身障害学研究 (ISSN:02851318)

巻号頁・発行日

vol.26, pp.7-19, 2002-03

被引用文献数

1

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本研究の目的は、日本語を母語とする聴覚障害児の韻律知覚能力を調べることである。そこで、2モーラ単語アクセントと2語文イントネーション(肯定/疑問)を用いて、弁別テストと識別テストを含む検査用バッテリを新たに開発した。これらの検査を東京都と千葉市にある小学校きこえの教室に通級する児童16名を対象に実施した。主な結果は、以下の通りである。1)アクセント、およびイントネーションの知覚能力と平均聴力レベルとの相関に関しては、中程度から高い負の相関(r=-0.494~-0.778)が認められた。平均聴力レベルが91dB以上(WHO の分類による最重度)であれば、アクセントとイントネーションの知覚は困難になることが示唆された。2)アクセント、およびイントネーションの知覚能力と語音明瞭度との相関に関しては、高い正の相関(r=0.694~0.966)が認められた。語音明瞭度が80%以上であれば、アクセントとイントネーションの知覚はより高いレベルになることが示唆された。

著者

Yi-Heng Li Yu-Wei Chiu Jun-Jack Cheng I-Chang Hsieh Ping-Han Lo Meng-Huan Lei Kwo-Chang Ueng Fu-Tien Chiang Shih-Hsien Sung Jen-Yuan Kuo Ching-Pei Chen Wen-Ter Lai Wen-Lieng Lee Jyh-Hong Chen Taiwan ACS STENT Registry Investigators

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-18-1283, (Released:2019-04-27)

参考文献数

23

被引用文献数

2

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Background:Little information is available in Asia about the real-world practice of dual antiplatelet therapy (DAPT) duration for acute coronary syndrome (ACS) and its influence on clinical outcomes.Methods and Results:The Taiwan ACS STENT Registry was a prospective, multicenter study to observe ACS patients using clopidogrel-based DAPT after percutaneous coronary intervention (PCI). The primary outcome was a composite of cardiovascular death, myocardial infarction, and stroke. Overall, 2,221 ACS patients (62 years, 83% men) were included. DAPT duration was ≤9 months in 935 (42.1%). The incidence of primary outcome was higher in patients receiving DAPT ≤9 months compared with those receiving DAPT >9 months at 1 year (3.5% vs. 1.6%, P=0.0026). The incidence of stent thrombosis (overall 0.5%) was similar between groups. Multivariable analysis showed that DAPT >9 months was associated with a significantly lower risk of primary outcome (odds ratio 0.725, 95% confidence interval 0.545–0.965).Conclusions:Our data showed that short duration of DAPT (≤9 months) was common (42.1%) in Taiwan for ACS patients undergoing PCI. DAPT ≤9 months increased the risk of the primary outcome.

著者

Li Yu-Yun Li Yi-Xuan Lo Tsai-Yun

出版者

Japanese Society for the Science of Design

雑誌

日本デザイン学会研究発表大会概要集

巻号頁・発行日

pp.229, 2015 (Released:2015-06-11)

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台湾では、今でも民間信仰が盛んで、各地に、そのような寺院が多く見られる。そして、毎年、 多様な場所で、多様な時間に、多様な祭りが行われている。祭りの行列は「陣頭」と呼ばれ、踊り 子、祭り囃子の奏者、神輿などが列をなし、町をねり歩く。「官将首」は「陣頭」の一つで、新荘の 地蔵庵が発祥である。「官将首」の「陣頭」は二人が基本の形であり、地蔵菩薩の護法将軍の仮 装をしている。二人、三人、五人、七人、またはそれ以上の将軍で構成され、各将軍の仮装やア クセサリーもまちまちである。例祭の時には、行列の前に立ち、厄除祈念や招福祈願の儀式をし、 町をねり歩き、人びとに加護を与える。現代では、生活様式が変わったことで、この祭りにおける住 民の連携は薄くなり、その文化的意義も薄まりつつある。 本研究の目的は、「官将首」の文化を再認識する事ができる生活用品の開発である。研究成 果として、「官将首」の民俗文化から、意匠特質を抽出し、「官将首」がもつ「加護」と「先導」とい う信仰的意味をのせた緊急用の照明器具を開発した。

著者

趙 怡 チョウ イ Yi Zhao

雑誌

駿河台大学論叢

巻号頁・発行日

no.40, pp.109-135, 2010

著者

新家 眞 北澤 克明 山本 哲也 澤田 明 岩瀬 愛子 山本 精一郎 吉村 健一 原 英彰 嶋澤 雅光 伊藤 保志 山嶋 哲盛 今村 和幸 笹岡 正顕 太田 貴史 水野 憲 川北 耕二 大橋 靖雄 白土 城照 山崎 芳夫 松本 長太 玉置 泰裕 相原 一 富所 敦男 永原 幸 山上 淳吉 古関 信之 石井 清 高山 淳 長谷川 智之 間山 千尋 内田 彩子 山田 秀之 大橋 正明 CHEN Yi-Ning 佐伯 忠賜朗 重枝 崇史 村田 博 LEE Kelvin 鶴我 英和 NAKAYAMA Mao 山岸 麗子

出版者

日本眼科学会

雑誌

日本眼科學会雜誌 (ISSN:00290203)

巻号頁・発行日

vol.115, no.3, pp.213-237, 2011-03-10

被引用文献数

2

著者

REN YI 佐藤 真 赤石 美奈

出版者

一般社団法人 人工知能学会

雑誌

JSAI大会論文集

巻号頁・発行日

vol.2013, pp.1F46, 2018-07-30

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<p>ニュースサイトに載っている記事は速報性と読みやすさを重視している。このため、ひとつひとつの記事の情報量が少ないという問題がある。個別の記事のみからでは、事件の全貌を知ることが難しい場合もある。そこで、読者がひとつの記事をきっかけとして、その事件の全貌を理解できるように支援するための手法に関する研究を行う。各方法の実験効果を比較し、ユーザーにその結果を提示する有効な手法を開発することを目指す。 </p>

著者

Wenkai Yan Yuqi Zhang Yating Zhang Ruifeng Cheng Yi Zhang Qichang Yang Tao Li

出版者

The Japanese Society for Horticultural Science

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.OKD-165, (Released:2018-08-03)

被引用文献数

13

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Light is one of the most limiting factors affecting plant growth in greenhouses. Recently, supplementary artificial light has been widely used in greenhouse production in winter or on overcast days when solar radiation is weak. However, plant responses to supplementary artificial light in a Chinese Solar Greenhouse (CSG) and the economic feasibility of the lighting strategy are poorly understood. The tomato, one of the most widely produced and consumed vegetables in the world, was tested in this study. A CSG was divided into three sections, and three treatments were arranged. They were top lighting with HPS lamps (TL), TL plus inter-lighting with LEDs (TL+IL), and control treatment without artificial light, respectively. We showed that supplementary artificial light improved the uniformity of light distribution from the south to north end of the CSG, and increased the average greenhouse temperature by ~1–1.4°C. Tomato yield was increased by 21.8% and 32.9% in TL and TL+IL, respectively, compared with that of the control. The higher yield under supplementary artificial light resulted from a larger number of ripe fruits rather than bigger fruit size. Moreover, fruit quality was improved by supplementary artificial light as indicated by a higher total soluble sugar content. There were no significant differences in total biomass production or total soluble sugar content in leaves, as well as fruits, between TL and TL+IL treatments, but TL+IL further stimulated fruit maturation compared with TL. Although supplementary artificial light confers an advantage in terms of tomato growth, it is not economically feasible as 28.8 kWh electricity was required to increase the tomato yield by 1 kg in the CSG. Therefore, it is important to find solutions to increase the efficiency of supplementary artificial light in the CSG.

著者

LIU YI UEMURA NAOMI XIAO SHU-DONG TYTGAT GUIDO N. J. TEN KATE FIEBO J. W.

雑誌

Journal of gastroenterology (ISSN:09441174)

巻号頁・発行日

vol.40, no.2, pp.123-127, 2005-02-01

参考文献数

24

被引用文献数

1

著者

Guo-dong Xu Lei Cai Yi-shu Ni Shi-yi Tian Ying-qi Lu Li-na Wang Lian-lian Chen Wen-ya Ma Shao-ping Deng

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.41, no.7, pp.1024-1033, 2018-07-01 (Released:2018-07-01)

参考文献数

54

被引用文献数

16

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Acarbose and voglibose are the most widely used diabetes drugs as glycosidase inhibitors. In this study, the use of these two inhibitors significantly increased the content of starch in large intestine, and altered the concentration of short-chain fatty acids (SCFAs) by affecting the intestinal microbiota. However, there are some differences in the intestinal microbiome of the two groups of mice, mainly in bacteria such as Bacteroidaceae bacteroides and Desulfovibrionaceae desulfovibrio. The productions of acetate and propionate in caecum in voglibose group were significantly higher than those in acarbose group and two kinds of glycosidase inhibitors were close in the production of butyrate in caecum. The Tax4Fun analysis based on Kyoto Encyclopedia of Genes and Genomes (KEGG) data indicated that different productions of acetate and propionate between acarbose group and voglibose group may be related to 2-oxoisovalerate dehydrogenase and pyruvate oxidase. In addition, in-vitro experiments suggested that voglibose had less effect on epithelial cells than acarbose after direct stimulation. According to the recent researches of SCFAs produced by intestinal microbiota, our comparative study shown higher concentration of these beneficial fatty acids in the lumen of voglibose-treated mice, which implied a lower level of inflammation.

著者

Saurabh P. Nagar Pratik P. Rane Kathleen M. Fox Juliana Meyers Keith Davis Anne Beaubrun Hyoe Inomata Yi Qian Kouji Kajinami

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.82, no.4, pp.1008-1016, 2018-03-23 (Released:2018-03-23)

参考文献数

29

被引用文献数

23

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Background:This study examined treatment patterns, possible statin intolerance, and incidence of cardiovascular events (CVEs) in 2 cohorts of patients with high cardiovascular risk (i.e., patients with atherosclerotic cardiovascular disease [ASCVD] and patients with diabetes mellitus).Methods and Results:A retrospective cohort study examined adults initiating either a statin or ezetimibe from 1 January 2006 to 31 May 2014 in the Japan Medical Data Center database. The first observed statin or ezetimibe prescription defined the index date. Patients had ≥12 months of pre- and post-index date plan enrollment. Two high-risk cohorts, the ASCVD cohort and diabetes cohort, were created based on diagnoses observed during the 12 months’ pre-index date. Treatment patterns, possible statin intolerance, and incidence of CVEs were reported. In the ASCVD cohort (n=5,302), 32.9% discontinued therapy, 7.7% switched to a non-index statin or non-statin lipid-lowering therapy, and 11.2% augmented index therapy in the 12 months’ post-index date; only 0.3% were using high-intensity statins and 10% had possible statin intolerance. Also, 8.1% had any new CVE during the follow-up period. Treatment patterns and incidence of CVEs among the diabetes cohort were similar to those of the ASCVD cohort.Conclusions:High cardiovascular risk Japanese patients had frequent treatment modifications, although use of high-intensity statin doses was rare. These patterns may indicate that alternative therapies for lipid lowering are needed.

著者

Nan-Yin CHEN Hsi-Huai LAI Tai-Hao HSU Fang-Yi LIN Jian-Zhi CHEN Hui-Chen LO

出版者

Japan Society for Bioscience, Biotechnology, and Agrochemistry

雑誌

Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)

巻号頁・発行日

vol.72, no.5, pp.1283-1289, 2008-05-23 (Released:2008-05-23)

参考文献数

18

被引用文献数

16

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Tremella mesenterica (TM) is a common food and folk medicine widely used in several Asian countries as a tonic for the lungs. In the present study, we compared the effects of extracellular polysaccharides (EPS), intracellular polysaccharides (IPS), and ethanol extract (EE) of Tremella mesenterica on the induction of apoptosis into human lung carcinoma A549 epithelial cells. The EE, but not the EPS or the IPS, almost completely inhibited the growth of A549 cells. The results of Annexin V-FITC/PI staining and flow cytometric analysis indicated that the percentage of Annexin V+/PI− cells in EE-treated cells increased to 32.8%. The results of further investigation showed a disruption of mitochondrial transmembrane potential (ΔΨm), the production of reactive oxygen species (ROS), and the activation of caspase-3 protein in EE-treated cells. These findings suggest that EE can decrease cell viability and induce apoptosis in A549 cell lines by activating a mitochondrial pathway.

著者

Yu-Shi Tian Yi Zhou Tatsuya Takagi Masanori Kameoka Norihito Kawashita

出版者

The Pharmaceutical Society of Japan

雑誌

Chemical and Pharmaceutical Bulletin (ISSN:00092363)

巻号頁・発行日

vol.66, no.3, pp.191-206, 2018-03-01 (Released:2018-03-01)

参考文献数

103

被引用文献数

42

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The global occurrence of viral infectious diseases poses a significant threat to human health. Dengue virus (DENV) infection is one of the most noteworthy of these infections. According to a WHO survey, approximately 400 million people are infected annually; symptoms deteriorate in approximately one percent of cases. Numerous foundational and clinical investigations on viral epidemiology, structure and function analysis, infection source and route, therapeutic targets, vaccines, and therapeutic drugs have been conducted by both academic and industrial researchers. At present, CYD-TDV or Dengvaxia® is the only approved vaccine, but potent inhibitors are currently under development. In this review, an overview of the viral life circle and the history of DENVs is presented, and the most recently reported antiviral candidates and newly discovered promising targets are focused and summarized. We believe that these successes and failures have enabled progress in anti-DENV drug discovery and hope that our review will stimulate further innovation in this area.

著者

Xun CHEN Xue-nong DUAN Li-min WANG Yi-ping CHEN Dun-dun WANG

出版者

The Japan Society of Mechanical Engineers

雑誌

Proceedings of the International Conference on Power Engineering : ICOPE (ISSN:24242942)

巻号頁・発行日

pp._ICOPE-15--_ICOPE-15-, 2015-11-30 (Released:2017-06-19)

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Under the circumstances of different inlet air heating modes for thermal units with rotary air preheaters using flue gas denitrification, in order to perform the comparison and analysis on the outlet gas and air temperatures, the wall temperature of the heat storage element, and the influencing trend and variation patterns of acid corrosion area and ammonium bisulfate deposition area, the thermodynamic properties of the air pre-heater are calculated. Based on the thermodynamic model, the calculation are done on the air pre-heater of a 600MW power plant, with hot air recirculation mode and inlet air heating mode respectively. The results show that in the hot air recirculation mode, with the hot air recirculation ratio increasing, the average outlet wall temperature of the cold-section goes up, while that of the hot-section goes down. Meanwhile, with the acid corrosion area in the cold-section shrinking, the ammonium bisulfate deposition area ascends, which intensifies ash clogging in the air pre-heater. In the steam air heating mode, the average outlet wall temperature of the heat storage elements at both the hot and cold section increase, and the acid corrosion and ammonium bisulfate buildup areas descend simultaneously. Thus, for the air heater of thermal power units using flue gas denitrification technology and high-sulphur coal, the calculations for thermal check should be conducted for winter peak load scenarios, and the inlet air heating by steam air heater is more preferable to be applied in practice.

著者

Jou-Hsuan Ho Yi-Ning Yeh Hui-Wen Wang Sok Kean Khoo Yieng-How Chen Chi-Fa Chow

出版者

Japanese Society for Food Science and Technology

雑誌

Food Science and Technology Research (ISSN:13446606)

巻号頁・発行日

vol.20, no.2, pp.337-343, 2014 (Released:2014-05-31)

参考文献数

25

被引用文献数

20

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Industrial wastewater containing heavy metals can become a serious environmental pollutant if not treated appropriately. Conventional treatment to remove toxic heavy metals can be expensive and may generate large amounts of toxic sludge. Regenerated natural wastes such as eggshells and eggshell membrane which are easily available, inexpensive, biodegradable, and have high adsorbability, can act as promising ‘green’ alternatives to remove heavy metal pollutants from wastewater. Here, we studied the adsorption capacity of eggshells with membrane (ESWM), eggshell membrane (ESM), and eggshells (ES) for the removal of nickel and silver ions in synthetic wastewater. Reaction time (1 to 72 h), metal ion concentration (25 to 200 mg/L), adsorbent dosage (0.1 to 0.8 g/20 mL), temperature (15°C to 45°C), and pH (1 to 9) were evaluated. Post-treatment nickel and silver concentrations were later analyzed using a spectrophotometer. Our results indicated increased removal of nickel and silver ions with increased adsorbent (all three ESWM, ESM, and ES) dosage, whereas the removal of nickel and silver ion decreased with increasing initial metal concentration. Among ESWM, ESM, and ES, ESM has the highest removal capacity and was the best adsorbent. The 0.8 g of ESM could remove 90.91% of nickel ions (100 mg/L) at 25°C, pH 5.76 and 24 h. On the other hand, approximately 100% of silver ions (25 mg/L) could be removed by 0.2 g of ESM at 25°C, pH 5.2, and 24 h. There was no difference in the adsorbability of ES and ESWM on nickel and silver ions. In summary, all three adsorbents, ESWM, ES, and ESM, can remove heavy metal ions from aqueous solution, with ESM having the highest efficiency. Hence, eggshell and its derivatives can be promising ‘green’ adsorbent materials for treating wastewater containing nickel and silver ions.