著者

日吉 正明 関谷 透 奥園 達也 野口 高昭

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.75, no.1special, pp.260-265, 1982 (Released:2011-11-04)

参考文献数

12

被引用文献数

4 5

---

A 17-year-old female high school student, suffered from attacks of vertigo after influenza vaccinations, which was diagnosed as vertigo consistent with vestibular neuronitis.She was completely healthy until she noted some dizziness on arising from a chair, which subsided spontaneously one hour after resting. This was on the 20th day after the first influenza vaccination.Two days after the first dizziness attack (22nd day after the first influenza vaccination), she began to have sudden, severe rotatory vertigo, 2 hours after the second vaccination. She had accompanying nausea and vomiting persisting for about half a day. Although the vertigo subsided she has developed unsteadiness of gait.There were no signs or findings of cochlear nervous impairment. Otoneurological findings including the caloric test and galvanic body-sway test (computed galvanogram, Yamaguchi University) were consistent with that of vestibular neuronitis. Sero-immunological study revealed a low level of viral antibody titre.The pathognomosis of vestibular neuronitis is briefly discussed.

著者

加藤 俊徳

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.70, no.10special1, pp.1029-1063, 1977-10-25 (Released:2011-11-04)

参考文献数

32

著者

吉本 裕

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.66, no.1, pp.57-60, 1973 (Released:2011-11-04)

参考文献数

4

著者

佐藤 修治

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.81, no.3, pp.433-452, 1988-03-01 (Released:2011-11-04)

参考文献数

53

被引用文献数

1 1

---

The cupula and the subcupular space were studied by scanning electron microscope (SEM) in ginea pigs, pigeons and chicks. Some ampullae were fractured by a styren lesion for observation of the relationship between the sensory hairs and the cupula. Electronmicroscopy revealed that the side of the cupula consists of a tubular structure. There were a number of small holes in the top and the bottom of the Cupula. On the surface of the crista were observed many small granules secreted by the supporting cells. Many sensory hair bundles traversed the subcupular space and were in contact with the cupular base.In a physiological study, the cupula of the Rana catesbiana was stimulated either by direct pressure or by mechanical endolymphatic flow. Action potentials from the posterior ampullary nerve were recorded before and after removal of the cupula and the subcupular substance. After cupular removal no action potential was evoked. When the cupula was replaced in the crista, the maximum frequency of the action potential in response to both direct pressure and mechanical endolymphatic flow recovered. However, the time course of the response was shorter than that prior to cupular removal.The cupula and the subcupular space were analyzed histochemically by light and electron microscopy. The ampulla of the chick was stained by periodic acid-Schiff (PAS), diastase-PAS, alcian blue-hyaluronidase, AB (pH2.5), AB (pH1.0), HID and AB-sialidase. The cupula and the intracellular microglomerus of the supporting cells contained mainly sialoglycoprotein (sialomucin). The cupula and the subcupular space were studied by both secondary electron (SE) image and backscattered electron (BSE) image. Ruthenium red (RR) staining was used for SEM observation of BSE image. The cupula and the granules of the crista surface contained mainly acid glyconjugate. Thus, the cupula and the gelatinous substance in the subcupular space contained mainly sialoglycoprotein.

著者

藤崎 茂巳 谷口 武彦 野入 輝男 堀内 邦夫 王 経州 黒田 道弘 山内 静子

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.52, no.3, pp.399-406, 1959 (Released:2011-10-14)

著者

井上 功 山本 砧三 武嶋 寛剛 中小 路澄子 貞岡 達也 坂哲 郎 垣鍔 典也 坂倉 淳 牧本 一男 高橋 宏明 和田 公平 大森 研史 林 伊吹 藤田 隆夫 渡辺 猛世 藤澤 俊二 宇野 功 野中 隆三郎

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.87, no.7, pp.985-995, 1994-07-01 (Released:2011-11-04)

参考文献数

5

---

The effectiveness, safety and usefulness of ketotifen nasal spray were investigated in 163 patients with allergic rhinitis. Ketotifen nasal spray (0.05mg/puff) was given four times daily for 4 weeks or more. “Slight to high” improvement was recorded in 92.4% of patients and “moderate to high” improvement in 61.0%.Overall usefulness was very high for both perennial and seasonal allergic rhinitis. Side effects were noted in six patients (3.7%). Drowsiness was noted in five patients and nasal mucosal pain in only one.The results of this study suggest that ketotifen nasal spray is very useful in the treatment of allergic rhinitis.

著者

青木 秀哲 毛利 大介 島津 薫 城山 明宏 湊川 徹

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.100, no.7, pp.545-553, 2007-07-01 (Released:2011-10-07)

参考文献数

11

---

Taste disorders can be caused by various factors, including zinc deficiency, adverse drug reactions, cold and xerostomia, and the number of patients seeking medical assistance for such disorders is increasing. However, because taste disorders are often difficult to treat, some medical institutions will not treat these complaints.In the Department of Otolaryngology at Osaka Dental University Hospital, a clinic was opened on September 1, 2004, to treat patients with taste disorders.We treated 1 outpatient who lost one side of parotid gland due to malignancy, then lost the function of the remaining salivary gland due to Sjögren's syndrome.Subjects comprised 17 patients complaining of taste disorders with xerostomia without subjective symptoms of other otolaryngological diseases.In the present study, 4 patients were prescribed zinc by another physician, but only 2 patients actually displayed zinc deficiency. Zinc administration did not improve symptoms in any of the patients.According to the diagnostic criteria for xerostomia in our department, 17 patients had xerostomia, and 4 of these 17 patients were diagnosed with Sjögren's syndrome. These patients were instructed to gargle with cevimeline hydrochloride, and taste sensation improved in 12 patients.We have examined 17 patients to data and consider this number insufficient to draw definitive conclusions but the data we have currently suggests to the following conclusions:1. Latent Sjögren's syndrome should be suspected in patients presenting with taste disorder with xerostomia.2. In taste disorder patients with xerostomia, gargling with cevimeline hydrochloride appears very useful.3. One patient had lost a side of salivary gland, and Sjögren's syndrome caused loss of function of the remaining salivary gland. In this patient, favorable results were also obtained by gargling with cevimeline hydrochloride.

著者

藤崎 茂巳 野入 輝男 堀内 邦夫 王 経州 末松 薫 山内 静子

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.51, no.12, pp.1213-1219, 1958 (Released:2011-10-14)

参考文献数

9

著者

勝見 直樹 岩武 博也 富澤 秀雄 肥塚 泉 加藤 功

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.93, no.3, pp.223-228, 2000-03-01 (Released:2011-11-04)

参考文献数

19

被引用文献数

5 3

---

We describe the case of a 25-year-old man with pain on turning his head to either side attributable to a malformation of the hyoid bone. When the neck was turned further to the left, the greater cornu slipped over the tuberculum anterius of the processus transversus, and locked in front of the tuberculum posterius. At the same time the thyroid cartilage caused an upward movement and separated the locked greater cornu. At the moment of this separation, a clicking sound was produced. Diagnosis was established using 3-dimensional reconstruction of CT imaging. The greater cornu of the hyoid bone was noted to be elongated and malformed, and the left greater cornu was obviously blocked by the processus transversus of cervical vertebra V. Excision of both greater cornua relieved the symptoms.

著者

石原 久司 牧原 靖一郎 宮武 智実 津村 宗近 假谷 伸

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.108, no.3, pp.243-247, 2015 (Released:2015-03-01)

参考文献数

20

被引用文献数

2 2

---

Longus colli calcific tendinitis is a secondary inflammation caused by the deposition of hydroxyapatite crystal in the longus colli tendon. It causes acute neck pain, limitations of neck movement and swallowing pain. The symptoms are usually resolved in 1 to 2 weeks when treated with analgesics and anti-inflammatory medications. A 45-year-old man visited our hospital with a complaint of severe neck pain and stiffness despite 3 days of therapy with loxoprofen prescribed by the first doctor he visited. Computed tomography (CT) imaging showed small calcification localized at the anterior C1-C2 level and a low density area in the retropharyngeal space without ring enhancement. A definitive diagnosis of longus colli calcific tendinitis was made. Cimetidine (100 mg twice daily) was added to his loxoprofen dosage. His neck pain improved remarkably in one day after commencing cimetidine treatment. And 3 days after starting the treatment his neck could be moved without limitation. On day 11 of the treatment, CT imaging showed reduction in the calcified deposit, and he was already completely asymptomatic. Cimetidine is an H2 receptor antagonist, and has been used for treatment of gastric ulcers. Furthermore, many studies have reported the treatment efficacy of cimetidine on calcific tendinitis of the shoulder. However, few studies have yet been reported on the longus colli tendon. Our report suggests that cimetidine may be effective against calcific tendinitis of the longus colli tendon as well as the shoulder. Because of the severe pain associated with this condition, patients often take large doses NSAIDs and need to be prescribed an anti-ulcer agent. In such a case, cimetidine may deserve consideration.

著者

古川 仭

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.86, no.3, pp.305-310, 1993-03-01 (Released:2011-11-04)

参考文献数

7

被引用文献数

3 1

---

Squamous cell carcinoma accounts for approximately 98 per cent of all malignant neoplasms that occur in the nasopharynx. The high incidence of nasopharyngeal carcinoma (NPC) is a characteristic of the Oriental races. Viral and environmental factors appear to have an etiologic impact on this disease. The most common sites are the lateral wall followed by the roof. NPC spreads primarily by local infiltration and regional metastases. Local infiltration of the eustachian tube is evidenced clinically when the patients presents with a unilateral conductive hearing loss secondary to the development of a secretory otitis media. Multiple cranial nerve deficits can develop. The maxillary and mandibular branches of the trigeminal complex (V2 and V3) are the most commonly involved cranial nerves and indicate extension of the tumor through the foramen rotundum and foramen ovale. Lateral rectus deficits cause the patient to complain of diplopia, especially on lateral gaze, indicating tumor involvement along the course of cranial nerve VI. More extensive internal and external ophthalmoplegias suggest orbital or cavernous sinus involvement. Lateral extension or spread into the pterygomaxillary fossa and the infratemporal fossa can easily affect the lower cranial nerves (IX, X, XI, XII), indicating that the tumor has progressed into the area of the jugular foramen. Lack of significant tumor bulk in the nasopharynx or parapharyngeal spaces with paralysis of the lower cranial nerves usually indicates involvement of adjacent lymph nodes surrounding the jugular foramen rather than direct extension from the primary tumor. Lymphatic spread from the nasopharynx may be either unilateral or bilateral. When the tumor has spread into the upper deep cervical lymph nodes, a cervical mass usually first becomes detectable clinically.

著者

山際 幹和 原田 輝彦 坂倉 康夫

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.84, no.6, pp.837-851, 1991-06-01 (Released:2011-11-04)

参考文献数

36

---

Without following the traditional diagnostic procedure based on oriental medicine, we administered an oral Kampo (traditional Chinese herbal) medicine, Tsumura Saiboku-to (7.5g/day), daily for 2 weeks to 108 patients with abnormal sensation in the throat, such as a lump or choking.After excluding 8 patients, 4 with unpleasant side effects and 4 who discontinued the medication, we evaluated the efficacy at the end of the first and second week of administration and one week after the termination of treatment in 38 males and 62 females. The medicine was considered to be very effective when the abnormal sensation improved subjectively by 80% or more, moderately effective if improvement was 50% to 80%, slightly effective if it was 30% to 50% and not effective if less than 300.The respective effectiveness rates were 22%, 32%, 11% and 35% at the end of the first week; and 35%, 33%, 12% and 20% at the end of the second weed; and 43%, 30%, 7% and 20% at the end of the third week. Further analysis of the data suggests that this medicine is more effective for females than males, for younger patients and those over 50, for non-drinking than habitually drinking patients, for those not previously treated, for those without cancer phobia, for those treated within one month after the start of abnormal sensation, for those with the sensation higher in the pharynx, and for those with lower neurotic scores on psychological tests.Side effects were reported by 6 (6%), 4 of whom stopped the medication: 4 had gastrointestinal symptoms and 2 had dry mouth and/or throat.From the point of view of western medicine, the effectiveness of Saiboku-to on abnormal sensation in the throat is good enough. It would probably be even better if administered after a selection based on diagnosis according to the concepts of oriental medicine.

著者

松永 信也 西園 浩文 平瀬 博之 岩下 睦郎

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.90, no.9, pp.1059-1062, 1997-09-01 (Released:2011-11-04)

参考文献数

13

---

A 76-year-old female was admitted to Izumi City Hospital with otalgia, a sore throat, dysphagia and dyspnea. A physical examination revealed ear and pharyngo-laryngeal herpetic lesions and a IX, X cranial nerve disorder. The patient underwent a tracheostomy on the second day of hospitalization because of laryngeal stenosis. Palsy involving the VII cranial nerve and auricular herpetic vesicles were recognized on the third hospital day. Otalgia, the sore throat and dysphagia were improved rapidly after acyclovir treatment. The W and K cranial nerve palsy was improved gradually, but the X cranial nerve disorder remain. Accordingly, physicians should be alert to the possibility of air way stenosis in cases of laryngeal herpes zoster.

著者

服部 浩

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.92, no.12, pp.1283-1290, 1999-12-01 (Released:2011-11-04)

参考文献数

20

---

The primary goal of this study was to verify the incidence and degree of hearing deterioration of JBSNDUE with a prospective long-term clinical follow-up.Of 173 JBSNDUE cases, 54 were followed up untill their ages reached 25-39 (average 30.7) years. In 23 cases (42.6%) hearing deterioration was confirmed. In 16 cases, discrimination scores for nonsense syllables were as low as 0%.The criteria of the “deterioration” of pure tones were irreversible average hearing level greater than 15dB at three adjoining frequencies between 0.25 and 4kHz.Except 25 of 173 cases, either binaural or monaural amplification was used. However, the incidence of hearing deterioration showed no significant difference between aided and unaided ears.The clinical features of JBSNDUE were summerized.The communication ability of those with deteriorated hearing was discussed.

著者

風間 保彦

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.69, no.6special, pp.743-755, 1976-06-20 (Released:2011-11-04)

参考文献数

35

著者

大野 覚 三浦 誠 市丸 和之

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.97, no.11, pp.983-986, 2004-11-01 (Released:2011-10-07)

参考文献数

11

被引用文献数

2 4

---

Two cases of denture foreign body in the esophagus were reported.A 74-year-old male with dementia due to Alzheimer's disease suddenly complained of dysphagia. A chest X-ray displayed a denture lodged in the esophagus, but the denture was not noticed at that time. Because he subsequently suffered from secondary aspiration pneumonia, he underwent tracheostomy and percutaneous endoscopic gastrostomy. After 3 years, by chance, the denture foreign body was detected by gastro-intestinal fiberscopy. His family did not consent to the removal of the foreign body.A 65-year-old male with mental retardation suddenly complained of dysphagia. A chest X-ray revealed a denture lodged in the esophagus the next day. The denture was removed under esophagoscopy with a Verda dilation laryngoscope without any complications.When the aged suddenly complain of dysphagia, presence of a foreign body in the esophagus should be ruled out, even if they are not aware of misswallowing foreign bodies.

著者

花田 武浩 鯵坂 孝二 今給黎 泰二郎 古田 茂 大山 勝

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.89, no.1, pp.11-19, 1996-01-01 (Released:2011-11-04)

参考文献数

21

---

Patients with sudden deafness who were treated either in our department or in our branch hospital between January 1984 and December 1994 were divided into two groups. Group A consisted of 69 patients who were treated with steroids, vasodilators, and stellate ganglion block but without hyperbaric oxygen therapy. Group B consisted of the other 85 patients who were treated with not only steroids, vasodilators, and stellate ganglion block but also with hyperbaric oxygen therapy. Patients in the two groups showed no significant difference in age, or number of patients with vertigo, but the initial audiogram was worse and time from onset to consultation were significantly greater in group B than those in group A. The prognoses of the two groups were analyzed by several issues, such as initial audiogram, time from onset to consult and there was no significant difference.

著者

金谷 浩一郎 今手 祐二 竹本 剛 蓮池 耕二 綿貫 浩一 守谷 啓司

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.95, no.2, pp.203-209, 2002-02-01 (Released:2011-11-04)

参考文献数

28

被引用文献数

1 2

---

PURPOSE: Tsumura Co.'s Bakumondo-to (TJ-29) is a Chinese herb medicine prescribed widely in Japan for bronchitis and laryngitis. It is well known that TJ-29 not only has a variety of effects including anti-inflammatory and antitussive properties, but also is capable of increasing salivary secretions. The purpose of this study is to examine whether TJ-29 can reduce mucosal toxicity caused by radiotherapy in patients with early laryngeal carcinoma.METHODS AND MATERIALS: Between 1993 and 1999, 20 patients with primary early laryngeal carcinoma were treated by radiotherapy at Nagato General Hospital. All patients were treated with 2 Gy per fraction daily, 5 days a week. Eight patients formed the control group (no TJ-29) and 12 patients received TJ-29 throughout the radiation therapy. The severity of daily subjective symptoms such as hoarseness, xerostomia or pharyngoxerosis, cough, and sore throat were graded O to 3 according to descriptions on the clinical charts.RESULTS: No statistically significant between-group differences were seen in subjective hoarseness, xerostomia or pharyngoxerosis, and cough. However the mean final grade of subjective sore throat was less severe in the TJ-29 group (p=0.023).CONCLUSION: Despite the limited number of patients, this study suggests that TJ-29 was able to reduce the severity of mucositis induced by radiotherapy. Further intensive research is needed.

著者

寺嶋 正治 加藤 太二 小林 仁和 宮国 泰明 田中 弘之

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.82, no.6, pp.805-817, 1989-06-01 (Released:2011-11-04)

参考文献数

22

---

Otteosynthesis using Champy's miniplates was performed in 8 patients with mid-face injuries. Since no patients complained of discomfort, we did not remove the miniplates which are thin and light. Miniplate osteosynthesis may be very useful in case of complicated fracture or old fracture of mid-face.

著者

藤木 暢也 内藤 泰 塩見 洋作 平野 滋 本庄 巖 長峯 隆 柴崎 浩

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.89, no.12, pp.1499-1506, 1996-12-01 (Released:2011-11-04)

参考文献数

15

---

Event-related magnetic fields (ERFs) were recorded in seven subjects when they were presented with a rectangle and Japanese Kanji characters, followed by vocalizations. The ERF averages for the Kanji characters were different from those for the rectangle at latencies of about 100ms over the occipital lobe and 150-500ms over the temporo-parieto-occipital region. This observation suggests that the first stage of visual word processing might arise in the occipital lobe.In some cases, difference between the ERFs for the Kanji characters and those for the rectangle were also seen in the frontal lobe at latencies greater than 250ms. This observation suggests that frontal lobe activity may be also involved in visual word processing.Three equivalent current dipoles were estimated on the bilateral precentral gyrus (motor area) and the posterior part of the superior frontal gyros (supplementary motor area) at a latency of about 500ms during vocalization.In some cases, early responses at latencies of less than 150ms were obtained in not only the occipital lobe but also the frontal and temporal lobes. This suggests that parallel processing might occur during visual word processing.