著者
柴崎 浩一 渡辺 卓也 長谷川 勝彦 山脇 敏裕
出版者
日本歯科大学新潟短期大学
雑誌
基盤研究(C)
巻号頁・発行日
2009

H. pyloriの初感染時期を推測する目的で、園児とその両親を対象に唾液中のH. pylori DNAの検出を行った。園児のH. pylori DNA検出率は年齢とともに上昇する傾向がみられ、4歳児と5歳児の間で有意に上昇していた。H. pylori陽性であった園児の母親のH. pylori陽性率は陰性児の母親の陽性率に比し有意に高率であった。これらは園児における初感染は3歳未満で起こっており、4.5歳間でも感染の危険性が高いことを示している。さらに、H. pylori陽性児の母親の陽性率が高かったことは母親から園児への感染が最も重要であることを示している。
著者
藤木 暢也 内藤 泰 塩見 洋作 平野 滋 本庄 巖 長峯 隆 柴崎 浩
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.89, no.12, pp.1499-1506, 1996-12-01 (Released:2011-11-04)
参考文献数
15

Event-related magnetic fields (ERFs) were recorded in seven subjects when they were presented with a rectangle and Japanese Kanji characters, followed by vocalizations. The ERF averages for the Kanji characters were different from those for the rectangle at latencies of about 100ms over the occipital lobe and 150-500ms over the temporo-parieto-occipital region. This observation suggests that the first stage of visual word processing might arise in the occipital lobe.In some cases, difference between the ERFs for the Kanji characters and those for the rectangle were also seen in the frontal lobe at latencies greater than 250ms. This observation suggests that frontal lobe activity may be also involved in visual word processing.Three equivalent current dipoles were estimated on the bilateral precentral gyrus (motor area) and the posterior part of the superior frontal gyros (supplementary motor area) at a latency of about 500ms during vocalization.In some cases, early responses at latencies of less than 150ms were obtained in not only the occipital lobe but also the frontal and temporal lobes. This suggests that parallel processing might occur during visual word processing.
著者
髙田 晋史 柴崎 浩平 中塚 雅也
出版者
地域農林経済学会
雑誌
農林業問題研究 (ISSN:03888525)
巻号頁・発行日
vol.57, no.4, pp.152-158, 2021-12-25 (Released:2021-12-25)
参考文献数
11

In this study, the process of generational change and the support system for successors in a small-scale community-based farming corporation in a hilly and mountainous area are considered. For this purpose, several interviews were conducted with the successors and other people concerned. As a result of the analysis, the following points about generational change were revealed. First, in order to secure successors from within the community, it is necessary to provide them with opportunities to be involved in agriculture from an early age. Second, after securing successors, management resources should be concentrated to provide a friendly working environment for them. Third, generational change is usually accompanied by a long period of time for successors. However, more time is needed for tasks where experience is required. Therefore, support from former manager and executives is necessary to continue after a generational change.
著者
佐藤 英司 前田 裕伸 本田 一典 伊藤 高史 月岡 恵 柴崎 浩一 吉益 均 市田 文弘
出版者
一般社団法人 日本肝臓学会
雑誌
肝臓 (ISSN:04514203)
巻号頁・発行日
vol.25, no.5, pp.674-681, 1984-05-25 (Released:2009-07-09)
参考文献数
14
被引用文献数
4 3

内痔核治療の目的で,市販漢方製剤(金鵄丸)を服用し,薬剤性肝障害をきたした2症例について報告する.第1例は51歳,女性.ドック健診にてGOT, GPTの軽度上昇を指摘され,精査のため第1回目の入院.その後経過良好で勤務していたが,全身倦怠感とともに,再びGOT, GPTの上昇がみられ第2回目の入院.入院加療後順調に回復.その後3回目のGOT,GPTの上昇がみられ,その際患者自身より,上記薬剤の服用後,全身倦怠感と肝機能の異常を指摘されるとの申し出があった.LMTは陰性,LSTは弱陽性を示したが,チャレンジテストにて確診した.第2例は46歳,女性.全身倦怠感にて来院.肝機能障害がみられ,その際,上記薬剤を服用したとのことで,LMT, LSTを施行したが,共に陰性.チャレンジテストによって確診した.
著者
杉浦 宏樹 山口 晃 柴崎 浩一
出版者
特定非営利活動法人 日本口腔科学会
雑誌
日本口腔科学会雑誌 (ISSN:00290297)
巻号頁・発行日
vol.55, no.2, pp.108-112, 2006-03-10 (Released:2011-01-31)
参考文献数
31

Introduction: Helicobacter pylori (H. pylori) DNA has been detected at a high prevalence in saliva. The aim of this study was to clarify the prevalence and the risk of intrafamilial transmission of H. pylori infection by detecting H. pylori DNA in saliva of Japanese children and their parents.Materials & Methods: Saliva was collected from 92 children and their parents, and nested PCR and PCRRFLP were used to detect and analyze H. pylori DNA. Subtyping by PCR-RFLP is considered to be useful in order to clarify the mode of transmission.Results: The detection rate of H. pylori DNA in saliva was 12.0%(11/92) in Japanese children, however, all of the children aged less than 6 years old were negative. All of the H.pylori infected children had H.pylori positive parents (both or only one), and in 7 out of 11 cases, children and their parents were infected with the sam e strain. Especially, in 6 cases, the subtype of both the child and the mother was the same.Conclusion: H. pylori DNA in saliva was detected in 12.0%, and parents-to-child, especially mother-to-child, transmission is the most likely route of intrafamilial infection of H. pylori.