著者

小島 通宏

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.69, no.1, pp.51-66, 1976 (Released:2011-11-04)

参考文献数

22

被引用文献数

5

著者

森山 寛

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.88, no.8, pp.980-982, 1995-08-01

参考文献数

1

被引用文献数

1

著者

大村 咲 北村 守正 平野 滋 楯谷 一郎 嘉田 真平 古田 一郎 三浦 誠 伊藤 壽一

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.107, no.8, pp.639-643, 2014

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We report herein on a case of minocycline-induced black thyroid with papillary thyroid carcinoma. A 60-year-old female, who had taken oral minocycline intermittently for osteomyelitis of the mandible for two years, noticed a palpable thyroid nodule. Fine needle aspiration of the nodule revealed atypical cells and the serum thyroglobulin level was high. Under the diagnosis of suspected thyroid carcinoma, a hemithyroidectomy with central compartment neck dissection was performed. The color of the tumor, which was diagnosed as a papillary carcinoma, was white. On the other hand, the color of the normal thyroid gland was dark red to black with minocycline pigmentation. Minocycline therapy may induce headache, nausea, vomiting, liver dysfunction and dental hyperpigmentation in children. But a minocycline-induced black thyroid is uncommon. Recently, there have been some reports that the risk of malignancy in black thyroid glands is higher than in non-black thyroids.

著者

山崎 可夫

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.63, no.8, pp.813-815, 1970-08-01 (Released:2011-10-14)

著者

家根 旦有

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.96, no.6, pp.486-487, 2003-06-01 (Released:2011-10-07)

参考文献数

2

著者

稲垣 千果夫 沖田 容一 折田 洋造

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.76, no.6, pp.1603-1610, 1983

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新生仔ゴールデンハムスターにおける蓋膜辺縁のコルチ器表面との接続形態について, 特に marginal pillar (MP) をスチレン樹脂割断法を併用してSEMで観察し, 次のような結果を得た.<br>1) MPは生後4-6日目の下方回転より出現し, 生後10-14日目にも顕著となり, 生後16日目には消失していた.<br>2) MPの出現部位は Deiters 細胞第三列目の細胞表面であり, 蓋膜下面への付着部位は辺縁よりもやや内側 (蝸牛軸側) であった.<br>3) 生後5-10日目頃では, Deiters 細胞第一列目, 二列目の細胞表面にもMPと同様の構造物を認めた.<br>ハムスターでは, MPの消失するのは聴毛の形態が完成した直後であり, 他の動物による諸家の報告を考え合わせれば, MPはコルチ器が完成するまでの間, 蓋膜を固定, 保持する作用を持つことは間違いないものと思われ, MPの消失がコルチ器の発達完了を示す指標になるものと考えられた.

著者

加藤 寛 田中 佐代子 由端 敏秀

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.77, no.6, pp.1367-1373, 1984-06-01 (Released:2011-11-04)

参考文献数

8

---

その主な周波数領域が1/3オクターブバンド400Hzから4kHzの胎内音を152名の新生児に聴かせ, その鎮静効果を観察した. そのうちの69名にABRを実施し胎内音の反応と比較した.その結果, 胎内音の鎮静効果とABRの反応とはよく一致した. 胎内音に反応の認められない高度難聴児2名が発見された.これらのことから, 本法は, 新生児聴覚スクリーニング検査として有用であるという確信を深めた.

著者

神田 智子 高橋 晴雄 長谷部 誠司 船曳 和雄

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.92, no.3, pp.239-243, 1999-03-01

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A case with a primary mastoid cholesterol cyst accompanying massive bone destruction is reported. The patient was a 43-year-old male, who visited our clinic because of vertigo. Otoneurological examination revealed the patient' s hearing and vestibular function to be nearly normal. A temporal bone CT showed a soft tissue mass in the left mastoid with large bone defects in the posterior and middle cranial fossae, and fistulas in all of the semicircular canals. MRI revealed a huge mass in the mastoid cavity apparently compressing the temporal lobe of the brain. The patient refused surgical treatment, and during the subsequent 4 year follow-up period the mass developed further and a cholesterol cyst was suspected based on the results of another MRI. Surgery revealed a huge cholesterol cyst located in the mastoid cavity with large bone defects and an exposed dura. Histological examination showed cholesterol granuloma accompanied by inflammation and bleeding and surrounded by thick scar tissue.<br>Obstructive and persistent inflammation in the mastoid was considered to be related to development of the mastoid cholesterol cyst.

著者

梅田 裕生 船曳 和雄 高橋 晴雄 長谷部 誠司

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.92, no.1, pp.27-30, 1999-01-01

被引用文献数

4 5

---

A case with post-traumatic cholesteatoma of the external auditory meatus extending into the mastoid is reported. A 27-year-old male visited our clinic with complaints of left otorrhea and hearing impairment lasting six months. He had suffered ahead injury three years previously. The left external auditory meatus was filled with otorrhea and debris, and an audiogram revealed slight conductive hearing loss. Computed tomography revealed a fracture line on the bony external auditory meatus and bone resorption at the medial part of the fracture near the eardrum. A soft tissue density mass was observed from the site of bone resorption to the mastoid antrum. During surgery, we found a temporal bone fracture filled with scar tissue, to which the external auditory meatus adhered. At the posterior part of the external auditory meatus medial to the fracture, the epithelium of the external auditory meatus had intruded into the antrum to form a cholesteatoma, which had extended into the whole mastoid cavity. Constriction of scar tissue at the fracture site during healing and a loss of ventilation at the mastoid were suggested to be involved in the pathogenesis of this cholesteatoma.

著者

松岡 寿子 西岡 慶子 河北 賢哉 多田羅 尚登

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.90, no.12, pp.1329-1335, 1997-12-01 (Released:2011-11-04)

参考文献数

33

被引用文献数

1

---

A 70-year-old male complaining of dizziness and hearing disturbances had sudden onset of meningitis and DIC. Target CT scans revealed latent petrositis with no clinical symptoms for six years. CT scans and MRI were found to be very useful in the early diagnosis of petrositis and the prediction of intracranial complications. This case suggested that asymptomatic petrositis with a high risk of intracranial complications is not rare in the recent antibiotic era. Twenty-three cases of petrositis reported in Japan from 1985 to 1995 were reviewed, and diagnostic and therapeutic problems were discussed.

著者

平澤 一浩 大塚 康司 伊藤 博之 上田 百合 白井 杏湖 鈴木 衞 永井 義幸 加藤 紀和 櫻井 衛

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.107, no.7, pp.529-533, 2014 (Released:2014-07-01)

参考文献数

20

被引用文献数

3

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Intranasal steroids are widely used to treat olfactory disorder, and are known to have fewer side effects than systemic steroids. However, there are some reports that intranasal steroids have induced adrenal insufficiency, even when the steroid dosage is appropriate. We encountered a case of secondary adrenal insufficiency after using intranasal betamethasone for olfactory disorder within the usual dosage. In this case, we were not aware of instructing the patient not to swallow the steroid which had dripped into her pharynx. Thus, a large amount of steroids which had passed through her nasal cavity might have been absorbed in the oropharyngeal mucosa and also ingested. That is possibly the main cause of developing adrenal insufficiency. Recently, Toki-shakuyaku-san, a traditional Chinese medicine, has started to be used for olfactory disorder after a cold. Because of its minimum side effects, it may be safely used for patients with the risk associated with steroid use.

著者

亀倉 隆太 坪田 大 新谷 朋子 今井 良吉 関 伸彦 上村 正見 浜本 誠 氷見 徹夫

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.99, no.11, pp.919-927, 2006-11-01 (Released:2011-10-07)

参考文献数

44

被引用文献数

1 4

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Small cell carcinoma is relatively common in the lung, but very rare in the head and neck region. We describe our experience with two extremely rare cases of small cell carcinoma arising in the nasal cavity and paranasal sinus.(Case 1) The patient was a 54-year-old man who had complained of left eyelid swelling and diplopia. He had a mass in the left maxillary sinus. He was treated with irradiation and chemotherapy. However, during the treatment, distant metastasis appeared in the skin and he died 4 months after the initial treatment.(Case 2) The patient was a 47-year-old woman who had complained of left nasal obstruction. She had a mass in the left nasal cavity. Surgical resection and postoperative radiotherapy were performed. However, after the initial treatment, a metastatic swelling of the left cervical lymph node appeared. Left neck dissection was performed, and she underwent two courses of adjuvant chemotherapy. Following the initial treatment, no evidence of recurrence has been observed for 29 months.

著者

中西 豊 竹内 英二 北野 博也 矢沢 代四郎 北嶋 和智

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.89, no.4, pp.429-433, 1996-04-01

被引用文献数

3 1

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We treated a 20-year-old man with a blind bullet wound of the left temporal bone and perforating bullet wounds of the right temporal legion, the right upper arm and right femur.<br>Following physical examination, X-P, and CT, a bullet was detected in the left temporal bone. However, other wounds did not contain bullets. Emergency surgery was performed. The bullet was suspected to have entered through the posterior part of the mastoid tip, pass through the mastoid cavity and stopped at the tympanum. The facial canal was partially broken at the vertical portion, however the facial nerve was not damaged. The bullet was removed after resecting the posterior external auditory canal. Tympanoplasty type i combined with external canal wall drilling-down technique was performed.<br>The patient showed left facial palsy after surgery. However, this gradually improved. The postoperative course in his left ear was good without infection, although the patient was deaf in that ear.

著者

毛利 学 西尾 正寿 毛利 純 島津 薫

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.72, no.10, pp.1373-1377, 1979-10-01 (Released:2011-11-04)

参考文献数

21

被引用文献数

1

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In performing tonsillectomies, we observe the following precautions: (1) the operation is performed under general anesthesia with fluothane with nitrous oxide and oxygen. (2) local epinephrine injection for the control of postoperative hemorrhage is avoided as there is the risk of evoking postoperative bleeding from reactive vasodilatation after the peripheral vasoconstrictive effect of the drug has worn off. (3) hemostasis is accomplished by ligation of vessels encountered during extirpation.During the past nine years, a total of 284 tonsillectomies among patients ranging from three to thirty-eight years were performed, adhering to these three principles. Gratifying results were obtained in 282 cases. Postoperative hemorrhage occurred in 2 patients. Examination of the surgical wound by direct laryngoscopy revealed the cause of bleeding to be loosening of a ligature. Another complication was dislocation of a central incisor in one case.

著者

綿貫 幸三

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.64, no.10, pp.1091-1093, 1971 (Released:2011-10-14)

参考文献数

5

著者

矢部 はる奈 五島 史行 林 賢 國弘 幸伸 小川 郁

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.100, no.6, pp.491-495, 2007-06-01 (Released:2011-10-07)

参考文献数

15

被引用文献数

1 1

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It is not easy to treat patients with intractable Meniere's disease. Intratympanic injection of gentamicin or steroid is one option. The other is a surgical procedure like endolymphatic shunt surgery. Middle ear pressure treatment using the Meniett device, which has not been approved by the Japanese government is widely accepted in foreign countries. We had a chance to use this Meniett device under approval of the ethic's committee of Hino Municipal Hospital since September 2004. ‹Methods› Four patients with intractable Meniere's disease who suffered intensive vertigo attack for more than 5 months with conservative medical treatment were employed in the study. Ages ranged from 67 to 72, with 3 females and 1 male. After a ventilation tube was inserted under local anesthesia, treatment with the Meniett was performed 3 times a day at home. ‹Results› Two patients improved and 2 slightly improved concerning vertigo attacks. One showed no change, 1 experienced a worsening, and 2 showed slight improvement concerning the hearing level. ‹Conclusion› The Meniett device is less invasive and may be suitable for elderly patients who prefer conservative treatment. The mechanism involved in the reduction of vertigo attacks is not clear so far, but we speculate that middle ear pressure may suppress serum vasopressin (antidiuretic hormone) secretion and thereby reduce endolymphatic hydrops. It is necessary to accumulate treatment data with the Meniett in Japan to obtain official approval by the government.

著者

亀井 民雄 石井 英男 中山 杜人

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.71, no.10, pp.1245-1256, 1978-10-01 (Released:2011-11-04)

参考文献数

34

被引用文献数

2 2

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Children with unilateral total deafness, indistinct in both etiology and time of onset, usually complain of only unilateral hearing loss. Nandate (1963) suggested terming this type of deafness “juvenile unilateral total deafness of unknown etiology”.On the other hand, our clinical experience has indicated that recurrent true vertigo develops preferentially in adolescence or early adulthood in such patients. The objective of this report was to introduce this new clinical aspect of this deafness.1. During the past 14 years, 89 patients with juvenile unilateral total deafness of unknown etiology were seen at the Gunma University Hospital. All patients conformed to the following criteria: i) Unilateral total deafness of unclear etiology and in which the onset of deafness could not be established to be other than very early in infancy; ii) Normal hearing in the other ear or, if deafness were present there also, normal hearing might be inferred to have existed in infancy; iii) Normal tympanic membranes; iv) Absence of central nervous symptoms. Of these patients, recurrent vertigo was the chief complaint of 27, or 30.3%. The age of onset of vertigo ranged from 9 to 60 years. However, in the majority of patients (19 cases: 70.4%), the onset was from 16 to 30 years. The vestibular symptoms were identical to vestibular symptoms seen in Ménière's disease.2. Among these 27 patients with recurrent vertigo of delayed onset, fluctuating sensory-neural auditory disturbances were evident in the originally non-deaf side in 3 (11.1%). These patients were diagnosed as having Ménière's disease.3. In contrast, vertigo attacks in the other 24 patients (88.9%) were never accompanied by cochlear symptoms. Such were considered to fit the delayed hydrops syndrome, a clinical entity newly postulated by Schuknecht (1976) and which is considered to occur as an aftermath of a labyrinthine injury of sufficient magnitude to destroy hearing but leaves the vestibular function intact.

著者

安田 宏一

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.69, no.11special, pp.1807-1810, 1976 (Released:2011-11-04)

参考文献数

12

被引用文献数

1

著者

森中 節子

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.79, no.Supplement1, pp.1-26, 1986-01-20 (Released:2011-11-04)

参考文献数

48

被引用文献数

2 2

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In order to clarify the role of the amygdaloid nucleus in equilibrium function, the following experiments were carried out: nine electric stimuli, 0.1 msec, 200Hz pulse waves at 3 volts during a 30-second period were applied daily to a rabbit's amygdaloid nucleus (medial or lateral area).Optokinetic nystagmus and the EEG in response to optic stimulation were measured before and after the nine electric stimuli.In addition, the blood pressure was measured in rabbits with repeated electric stimulation of the medial or lateral area of the same amygdaloid nucleus. Stimulation was with 0.1 msec, 200Hz pulse waves at 30 volts for about 23 seconds.(1) Rabbits with repeated electric stimulation of the medial area of the amygdaloid nucleus tended to show increased optokinetic nystagmus and increased EEG activity in response to optic stimulation. Furthermore, their blood pressure increased when the medial area was stimulated.(2) Rabbits with repeated electric stimulation of the lateral area of the amygdaloid nucleus tended to show reduced optokinetic nystagmus and EEG activity and a decrease in blood pressure.The following conclusions were drawn:(1) The amygdaloid nucleus correlates with the brain stem, particularly the ascending activating system, in the maintenance of equilibrium.(2) The medial area of the amygdaloid nucleus actively participates in the maintenance of equilibrium function, promoting activity of the brain stem. The lateral area of the amygdaloid nucleus has an opposite function and seems to inhibit overexcitement of the brain stem, resulting in smooth maintenance of body equilibrium.

著者

藤田 裕人 小泉 敏三 乾 洋史 伊藤 妙子 北原 糺

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.116, no.9, pp.851-857, 2023 (Released:2023-09-01)

参考文献数

21

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There have been many reports of endolymphatic hydrops (EH) in patients with Meniere’s disease (MD) since the first report by Hallpike and Yamakawa in 1938. Mental/physical stress and subsequent increase in release of the stress hormone arginine vasopressin (AVP) supposedly triggers MD. Recently, many lines of evidence have suggested the possibility that AVP is closely linked to the formation of EH in cases of MD. In the present study, we attempted to investigate the relationship between stress and EH in patients with unilateral Meniere’s disease (uMD).We enrolled 113 definite uMD patients from July 2014 to October 2019. All patients underwent 3-T magnetic resonance imaging (MRI) 4 hours after intravenous gadolinium injection. We adopted the criteria for evaluation of EH proposed by Nakashima et al. Stress was evaluated using the depressive self-rating scale (SDS), the psychological stress response scale (SRS), and the dizziness handicap inventory (DHI) modified by Nishiike et al. These stress scores and the blood AVP levels were compared in patients with EH.There was no significant correlation between EH and the stress scores on the affected side, but the anxiety score showed a significant correlation with EH on the sound side (p = 0.04). There was no significant correlation between the EH and AVP in either the affected side or the sound side. We suppose that the formation of EH involves a complex process of stresses.